Longitudinal Effects of Medication Nonadherence on Glycemic Control

Annals of Pharmacotherapy

Volumn 48, Issue 5, 2014, Pages 562-570

  Egede, Leonard E ^a,b   Gebregziabher, Mulugeta ^b   Echols, Carrae ^c   Lynch, Cheryl P ^a,b  

^a RALPH H JOHNSON VA MEDICAL CENTER   (United States)

^b MEDICAL UNIVERSITY OF SOUTH CAROLINA   (United States)

^c United States Department of Labor   (United States)

Author keywords

databases; epidemiology; outcomes research analysis; type 2 diabetes

Indexed keywords

HEMOGLOBIN A1C; INSULIN; ORAL ANTIDIABETIC AGENT;

AGED; ARTICLE; COHORT ANALYSIS; COMORBIDITY; CONGESTIVE HEART FAILURE; DIVORCED PERSON; ETHNICITY; FEMALE; FOLLOW UP; GLYCEMIC CONTROL; HEMOGLOBIN BLOOD LEVEL; HUMAN; HYPERTENSION; ISCHEMIC HEART DISEASE; LONGITUDINAL STUDY; MAJOR CLINICAL STUDY; MALE; MARRIAGE; NON INSULIN DEPENDENT DIABETES MELLITUS; OUTCOME ASSESSMENT; POSTTRAUMATIC STRESS DISORDER; PRIORITY JOURNAL; PSYCHOSIS; RACE; SUBSTANCE ABUSE; TREATMENT REFUSAL; VETERAN; WIDOWED PERSON;

DATABASES; EPIDEMIOLOGY; OUTCOMES RESEARCH/ANALYSIS; TYPE 2 DIABETES;

AGED; DIABETES MELLITUS, TYPE 2; FEMALE; HEMOGLOBIN A, GLYCOSYLATED; HUMANS; HYPOGLYCEMIC AGENTS; LINEAR MODELS; MALE; MEDICATION ADHERENCE; MIDDLE AGED; VETERANS;

EID: 84898678920     PISSN: 10600280     EISSN: 15426270     Source Type: Journal    
DOI: 10.1177/1060028014526362     Document Type: Article

References (30)

1. Ho PM,Rumsfeld JS,Masoudi FA, et al.Effect of medication nonadherence on hospitalization and mortality among patients with diabetes mellitus.Arch Intern Med. 2006;166:1836-1841.
2. Adams AS,Trinacty CM,Zhang F, et al.Medication adherence and racial differences in A1C control.Diabetes Care. 2008;31:916-921.
3. Pladevall M,Williams LK,Potts LA,Divine G,Xi H,Lafata JE.Clinical outcomes and adherence to medications measured by claims data in patients with diabetes.Diabetes Care. 2004;27:2800-2805.
4. Bartels D.Adherence to oral therapy for type 2 diabetes: opportunities for enhancing glycemic control.J Am Acad Nurse Pract. 2004;16:8-16.
5. Nelson KM,McFarland L,Reiber G.Factors influencing disease self-management among veterans with diabetes and poor glycemic control.J Gen Intern Med. 2007;22:442-447.
6. Yang Y,Thumula V,Pace PF,Banahan BF,Wilkin NE,Lobb WB.Predictors of medication nonadherence among patients with diabetes in Medicare Part D programs: a retrospective cohort study.Clin Ther. 2009;31:2178-2188.
7. Schectman JM,Nadkarni MM,Voss JD.The association between diabetes metabolic control and drug adherence in an indigent population.Diabetes Care. 2002;25:1015-1021.
8. Shenolikar RA,Balkrishnan R,Camacho FT,Whitmire JT,Anderson RT.Race and medication adherence in Medicaid enrollees with type-2 diabetes.J Natl Med Assoc. 2006;98:1071-1077.
9. Heisler M,Faul JD,Hayward RA,Langa KM,Blaum C,Weir D.Mechanisms for racial and ethnic disparities in glycemic control in middle-aged and older Americans in the health and retirement study.Arch Intern Med. 2007;167:1853-1860.
10. Bezie Y,Molina M,Hernandez N,Batista R,Niang S,Huet D.Therapeutic compliance: a prospective analysis of various factors involved in the adherence rate in type 2 diabetes.Diabetes Metab. 2006;32:611-616.
11. Kalsekar ID,Madhavan SS,Amonkar MM, et al.Depression in patients with type 2 diabetes: impact on adherence to oral hypoglycemic agents.Ann Pharmacother. 2006;40:605-611.
12. Grant R,Adams AS,Trinacty CM, et al.Relationship between patient medication adherence and subsequent clinical inertia in type 2 diabetes glycemic management.Diabetes Care. 2007;30:807-812.
13. Hunt J,Rozenfeld Y,Shenolikar R.Effect of patient medication cost share on adherence and glycemic control.Manag Care. 2009;18:47-53.
14. Piette JD,Wagner TH,Potter MB,Schillinger D.Health insurance status, cost-related medication underuse, and outcomes among diabetes patients in three systems of care.Med Care. 2004;42:102-109.
15. Horswell RL,Wascom CK,Cerise FP,Besse JA,Johnson JK.Diabetes mellitus medication assistance program: relationship of effectiveness to adherence.J Health Care Poor Underserved. 2008;19:677-686.
16. Rustveld LO,Pavlik VN,Jibaja-Weiss ML,Kline KN,Gossey JT,Volk RJ.Adherence to diabetes self-care behaviors in English- and Spanish-speaking Hispanic men.Patient Prefer Adherence. 2009;3:123-130.
17. Vijan S,Hayward RA,Ronis DL,Hofer TP.Brief report: the burden of diabetes therapy: implications for the design of effective patient-centered treatment regimens.J Gen Intern Med. 2005;20:479-482.
18. Maynard C,Chapko MK.Data resources in the Department of Veterans Affairs.Diabetes Care. 2004;27:B22-B26.
19. Miller DR,Safford MM,Pogach LM.Who has diabetes? Best estimates of diabetes prevalence in the Department of Veterans Affairs based on computerized patient data.Diabetes Care. 2004;27:B10-B21.
20. Karve S,Cleves MA,Helm M,Hudson TJ,West DS,Martin BC.An empirical basis for standardizing adherence measures derived from administrative claims data among diabetic patients.Med Care. 2008;46:1125-1133.
21. Farmer KC.Methods for measuring and monitoring medication regimen adherence in clinical trials and clinical practice.Clin Ther. 1999;21:1074-1090.
22. Hess LM,Raebel MA,Conner DA,Malone DC.Measurement of adherence in pharmacy administrative databases: a proposal for standard definitions and preferred measures.Ann Pharmacother. 2006;40:1280-1287.
23. Cramer JA,Pugh MJ.The influence of insulin use on glycemic control: how well do adults follow prescriptions for insulin?.Diabetes Care. 2005;28:78-83.
24. Lau DT,Nau DP.Oral antihyperglycemic medication nonadherence and subsequent hospitalization among individuals with type 2 diabetes.Diabetes Care. 2004;27:2149-2153.
25. Quan H,Sundararajan V,Halfon P, et al.Coding algorithms for defining comorbidities in ICD-9-CM and ICD-10 administrative data.Med Care. 2005;43:1130-1139.
26. Diggle PJ,Heagerty P,Liang K-Y,Zeger SLAnalysis of Longitudinal Data. 2nd ed.Oxford, UK: Oxford University Press; 2002.Oxford, UK: Oxford University Press; 2002:.
27. Ibrahim JG,Molenberghs G.Missing data methods in longitudinal studies: a review.TEST. 2009;18:1-43.
28. Lee JK,Grace KA,Taylor AJ.Effect of a pharmacy care program on medication adherence and persistence, blood pressure, and low-density lipoprotein cholesterol: a randomized controlled trial.JAMA. 2006;296:2563-2571.
29. Lindenmeyer A,Hearnshaw H,Vermeire E,Van Royen P,Wens J,Biot Y.Interventions to improve adherence to medication in people with type 2 diabetes mellitus: a review of the literature on the role of pharmacists.J Clin Pharm Ther. 2006;31:409-419.
30. Conn VS,Hafdahl AR,Cooper PS,Ruppar TM,Mehr DR,Russell CL.Interventions to improve medication adherence among older adults: meta-analysis of adherence outcomes among randomized controlled trials.Gerontologist. 2009;49:447-462.