Fetal cannabinoid receptors and the "dis-joint-ed" brain

EMBO Journal

Volumn 33, Issue 7, 2014, Pages 665-667

  Cristino, Luigia ^a   Di Marzo, Vincenzo ^a  

^a CNR   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

BINDING PROTEIN; CANNABINOID 1 RECEPTOR; CANNABINOID RECEPTOR; CANNABIS; ENDOCANNABINOID; PROTEIN; SCG10 PROTEIN; STATHMIN; STATHMIN 2; TETRAHYDROCANNABINOL; UNCLASSIFIED DRUG; DRONABINOL; PSYCHOTROPIC AGENT; SIGNAL PEPTIDE; STMN2 PROTEIN, MOUSE;

ARTICLE; BRAIN REGION; CANNABIS ADDICTION; CANNABIS SMOKING; CELL MIGRATION; DEVELOPMENTAL STAGE; FETUS DEVELOPMENT; MICROTUBULE; NERVE CELL; NERVE FIBER GROWTH; NONHUMAN; PREGNANCY; PRENATAL EXPOSURE; PRIORITY JOURNAL; PROGENY; PROTEIN PHOSPHORYLATION; SUBSTANCE ABUSE; ANIMAL; BRAIN CORTEX; DRUG EFFECTS; FEMALE; HIPPOCAMPUS; HUMAN; MALE; METABOLISM;

ANIMALS; CEREBRAL CORTEX; DRONABINOL; FEMALE; HIPPOCAMPUS; HUMANS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MALE; PREGNANCY; PSYCHOTROPIC DRUGS; RECEPTOR, CANNABINOID, CB1;

EID: 84898661855     PISSN: 02614189     EISSN: 14602075     Source Type: Journal    
DOI: 10.1002/embj.201488086     Document Type: Article

References (14)

1. Berghuis P, Rajnicek AM, Morozov YM, Ross RA, Mulder J, Urbán GM, Monory K, Marsicano G, Matteoli M, Canty A, Irving AJ, Katona I, Yanagawa Y, Rakic P, Lutz B, Mackie K, Harkany T, (2007) Hardwiring the brain: endocannabinoids shape neuronal connectivity. Science 316: 1212-6 (Pubitemid 46880959)
2. Berrendero F, Sepe N, Ramos JA, Di Marzo V, Fernández-Ruiz JJ, (1999) Analysis of cannabinoid receptor binding and mRNA expression and endogenous cannabinoid contents in the developing rat brain during late gestation and early postnatal period. Synapse 33: 181-91 (Pubitemid 29372845)
3. Fried P, Watkinson B, James D, Gray R, (2002) Current and former marijuana use: preliminary findings of a longitudinal study of effects on IQ in young adults. CMAJ 166: 887-91 (Pubitemid 34275508)
4. Grenningloh G, Soehrman S, Bondallaz P, Ruchti E, Cadas H, (2004) Role of the microtubule destabilizing proteins SCG10 and stathmin in neuronal growth. J Neurobiol 58: 60-9 (Pubitemid 37543338)
5. Huizink AC, Mulder EJ, (2006) Maternal smoking, drinking or cannabis use during pregnancy and neurobehavioral and cognitive functioning in human offspring. Neurosci Biobehav Rev 30: 24-41 (Pubitemid 41779405)
6. Hutchings DE, Hutchings DE, Martin BR, Gamagaris Z, Miller N, Fico T, (1989) Plasma concentrations of Δ9-tetrahydrocannabinol in dams and fetuses following acute or multiple prenatal dosing in rats. Life Sci 44: 697-701 (Pubitemid 19065969)
7. Kostovic I, Judaš M, (2010) The development of the subplate and thalamocortical connections in the human foetal brain. Acta Paediatr 99: 1119-1127
8. Passey ME, Sanson-Fisher RW, D'Este CA, Stirling JM, (2014) Tobacco, alcohol and cannabis use during pregnancy: clustering of risks. Drug Alcohol Depend 134: 44-50
9. Pijlman FT, Rigter SM, Hoek J, Goldschmidt HM, Niesink RJ, (2005) Strong increase in total delta-THC in cannabis preparations sold in Dutch coffee shops. Addict Biol 10: 171-80 (Pubitemid 40976387)
10. Porter BE, Jacobson C, (2013) Report of a parent survey of cannabidiol-enriched cannabis use in pediatric treatment-resistant epilepsy. Epilepsy Behav 29: 574-7
11. Substance Abuse and Mental Health Services Administration (2012) Mental Health, United States, 2010. HHS Publication No. (SMA) 12-4681. Rockville, MD: Substance Abuse and Mental Health Services Administration.
12. Shabani M, Mahnam A, Sheibani V, Janahmadi M, (2014) Alterations in the intrinsic burst activity of Purkinje neurons in offspring maternally exposed to the CB1 Cannabinoid agonist WIN 55212-2. J Membr Biol 247: 63-72
13. Shin JE, Miller BR, Babetto E, Cho Y, Sasaki Y, Qayum S, Russler EV, Cavalli V, Milbrandt J, DiAntonio A, (2012) SCG10 is a JNK target in the axonal degeneration pathway. Proc Natl Acad Sci USA 109: E3696-705
14. Tortoriello G, Morris CV, Alpar A, Fuzik J, Shirran SL, Calvigioni D, Keimpema E, Botting CH, Reinecke K, Herdegen T, Courtney M, Hurd YL, Harkany T, (2014) Miswiring the brain: Δ9-tetrahydrocannabinol disrupts cortical development by inducing an SCG10/stathmin-2 degradation pathway. EMBO J DOI 10.1002/embj.201386035