Wnt/β-catenin signaling pathway and lipolysis enzymes participate in methylprednisolone induced fat differential distribution between subcutaneous and visceral adipose tissue

Steroids

Volumn 84, Issue , 2014, Pages 30-35

  Xiao, Xinhua ^a   Li, Han ^a   Yang, Jiaojiao ^a   Qi, Xiaoyan ^a   Zu, Xuyu ^b   Yang, Jing ^a   Zhong, Jing ^b   Cao, Renxian ^a   Liu, Jianghua ^a   Wen, Gebo ^a  

^a UNIVERSITY OF SOUTH CHINA   (China)

^b THE FIRST AFFILIATED HOSPITAL OF UNIVERSITY OF SOUTH CHINA   (China)

Author keywords

Adipogenesis; Lipolysis; Methylprednisolone; Subcutaneous adipose tissue; Visceral adipose tissue

Indexed keywords

ADIPOSE TRIGLYCERIDE LIPASE; BETA CATENIN; DICKKOPF 1 PROTEIN; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; HORMONE SENSITIVE LIPASE; LOW DENSITY LIPOPROTEIN CHOLESTEROL; METHYLPREDNISOLONE; TRIACYLGLYCEROL; TRIACYLGLYCEROL LIPASE; UNCLASSIFIED DRUG; WNT PROTEIN; PRIMER DNA;

ANIMAL TISSUE; ARTICLE; CHOLESTEROL BLOOD LEVEL; FEMALE; INTRAABDOMINAL FAT; LIPOLYSIS; NONHUMAN; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; RAT; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; SUBCUTANEOUS FAT; TRIACYLGLYCEROL BLOOD LEVEL; WESTERN BLOTTING; ANIMAL; DRUG EFFECTS; ENZYMOLOGY; METABOLISM; NUCLEOTIDE SEQUENCE; SPRAGUE DAWLEY RAT;

ANIMALS; BASE SEQUENCE; BETA CATENIN; DNA PRIMERS; FEMALE; INTRA-ABDOMINAL FAT; LIPASE; LIPOLYSIS; METHYLPREDNISOLONE; RATS; RATS, SPRAGUE-DAWLEY; REAL-TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; SUBCUTANEOUS FAT; WNT PROTEINS;

EID: 84898657670     PISSN: 0039128X     EISSN: 18785867     Source Type: Journal    
DOI: 10.1016/j.steroids.2014.03.004     Document Type: Article

References (32)

1. C. Grossmann, T. Scholz, and M. Rochel et al. Transactivation via the human glucocorticoid and mineralocorticoid receptor by therapeutically used steroids in CV-1 cells: a comparison of their glucocorticoid and mineralocor (Pubitemid 39307329)
2. P. Björntorp Hormonal control of regional fat distribution Hum Reprod 12 Suppl. 1 1997 21 25
3. K.A. Longo, W.S. Wright, and S. Kang et al. Wnt10b inhibits development of white and brown adipose tissues J Biol Chem 279 34 2004 35503 35509 (Pubitemid 39100550)
4. W.S. Wright, K.A. Longo, and V.W. Dolinsky et al. Wnt10b inhibits obesity in ob/ob and agouti mice Diabetes 56 2 2007 295 303
5. S. Gesta, M. Blüher, and Y. Yamamoto et al. Evidence for a role of developmental genes in the origin of obesity and body fat distribution Proc Natl Acad Sci USA 103 17 2006 6676 6681
6. C. Christodoulides, A. Scarda, and M. Granzotto et al. WNT10B mutations in human obesity Diabetologia 49 4 2006 678 684 (Pubitemid 43357541)
7. I.C. Kim, M.H. Cha, and D.M. Kim et al. A functional promoter polymorphism -607G > C of WNT10B is associated with abdominal fat in Korean female subjects J Nutr Biochem 22 3 2011 252 258
8. T.C. Prestwich, and O.A. Macdougald Wnt/beta-catenin signaling in adipogenesis and metabolism Curr Opin Cell Biol 19 6 2007 612 617
9. D.M. Kim, H.R. Choi, and A. Park et al. Retinoic acid inhibits adipogenesis via activation of Wnt signaling pathway in 3T3-L1 preadipocytes Biochem Biophys Res Commun 434 3 2013 455 459
10. H. Lee, S. Bae, and K. Kim et al. Shikonin inhibits adipogenesis by modulation of the WNT/β-catenin pathway Life Sci 88 7-8 2011 294 301
11. M. Naito, K. Omoteyama, and Y. Mikami et al. Inhibition of Wnt/β-catenin signaling by dexamethasone promotes adipocyte differentiation in mesenchymal progenitor cells, ROB-C26 Histochem Cell Biol 138 6 2012 833 845
12. M. Rebuffe-Scrive, M. Krotkiewski, and J. Elfverson et al. Muscle and adipose tissue morphology and metabolism in Cushing's syndrome J Clin Endocrinol Metab 67 6 1988 1122 1128 (Pubitemid 19012940)
13. M. Rebuffe-Scrive, U.A. Walsh, and B. McEwen et al. Effect of chronic stress and exogenous glucocorticoids on regional fat distribution and metabolism Physiol Behav 52 3 1992 583 590
14. J.E. Campbell, A.J. Peckett, and A.M. D'souza et al. Adipogenic and lipolytic effects of chronic glucocorticoid exposure Am J Physiol Cell Physiol 300 1 2011 C198 C209
15. C. Xu, J. He, and H. Jiang et al. Direct effect of glucocorticoids on lipolysis in adipocytes Mol Endocrinol 23 8 2009 1161 1170
16. B.G. Slavin, J.M. Ong, and P.A. Kern Hormonal regulation of hormone-sensitive lipase activity and mRNA levels in isolated rat adipocytes J Lipid Res 35 9 1994 1535 1541 (Pubitemid 24291214)
17. M. Ottosson, P. Lonnroth, and P. Bjorntorp et al. Effects of cortisol and growth hormone on lipolysis in human adipose tissue J Clin Endocrinol Metab 85 2 2000 799 803 (Pubitemid 32279603)
18. M. Di Girolamo, S. Mendlinger, and J.W. Fertig A simple method to determine fat cell size and number in four mammalian species Am J Physiol 221 3 1971 850 858
19. C. Rattarasarn, R. Leelawattana, and S. Soonthornpun et al. Relationships of body fat distribution, insulin sensitivity and cardiovascular risk factors in lean, healthy non-diabetic Thai men and women Diabetes Res Clin Pract 60 2 2003 87 94 (Pubitemid 36434259)
20. E. Arner, P.O. Westermark, and K.L. Spalding et al. Adipocyte turnover: relevance to human adipose tissue morphology Diabetes 59 1 2010 105 109
21. P. Bjorntorp, and R. Rosmond Obesity and cortisol Nutrition 16 10 2000 924 936
22. Z. Michailidou, M.D. Jensen, and D.A. Dumesic et al. Omental 11beta-hydroxysteroid dehydrogenase 1 correlates with fat cell size independently of obesity Obesity (Silver Spring) 15 5 2007 1155 1163 (Pubitemid 46932470)
23. P.M. Stewart, and J.W. Tomlinson Cortisol, 11 beta-hydroxysteroid dehydrogenase type 1 and central obesity Trends Endocrinol Metab 13 3 2002 94 96 (Pubitemid 36733994)
24. C.N. Bennett, S.E. Ross, and K.A. Longo et al. Regulation of Wnt signaling during adipogenesis J Biol Chem 277 34 2002 30998 31004 (Pubitemid 34970803)
25. H. Hauner, G. Entenmann, and M. Wabitsch et al. Promoting effect of glucocorticoids on the differentiation of human adipocyte precursor cells cultured in a chemically defined medium J Clin Invest 84 5 1989 1663 1670 (Pubitemid 19272257)
26. C. Pantoja, J.T. Huff, and K.R. Yamamoto Glucocorticoid signaling defines a novel commitment state during adipogenesis in vitro Mol Biol Cell 19 10 2008 4032 4041
27. S.E. Ross, N. Hemati, and K.A. Longo et al. Inhibition of adipogenesis by Wnt signaling Science 289 5481 2000 950 953 (Pubitemid 30659947)
28. V. Krishnan, H.U. Bryant, and O.A. Macdougald Regulation of bone mass by Wnt signaling J Clin Invest 116 5 2006 1202 1209
29. J.S. Samra, M.L. Clark, and S.M. Humphreys et al. Effects of physiological hypercortisolemia on the regulation of lipolysis in subcutaneous adipose tissue J Clin Endocrinol Metab 83 2 1998 626 631 (Pubitemid 28496549)
30. R.C. Andrews, O. Herlihy, and D.E. Livingstone et al. Abnormal cortisol metabolism and tissue sensitivity to cortisol in patients with glucose intolerance J Clin Endocrinol Metab 87 12 2002 5587 5593 (Pubitemid 36034364)
31. E.E. Kershaw, J.K. Hamm, and L.A. Verhagen et al. Adipose triglyceride lipase: function, regulation by insulin, and comparison with adiponutrin Diabetes 55 1 2006 148 157 (Pubitemid 43343310)
32. H. Masuzaki, J. Paterson, and H. Shinyama et al. A transgenic model of visceral obesity and the metabolic syndrome Science 294 5549 2001 2166 2170 (Pubitemid 33150673)