The application of root mean square electrocardiography (RMS ECG) for the detection of acquired and congenital long QT syndrome

PLoS ONE

Volumn 9, Issue 1, 2014, Pages

  Lux, Robert L ^a   Sower, Christopher Todd ^a   Allen, Nancy ^a   Etheridge, Susan P ^a   Tristani Firouzi, Martin ^a   Saarel, Elizabeth V ^a  

^a UNIVERSITY OF UTAH SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

LEAD; MOXIFLOXACIN; PLACEBO;

ADOLESCENT; ADULT; AGED; ARTICLE; CHILD; CONGENITAL DISORDER; CONGENITAL LONG QT SYNDROME; CONTROLLED STUDY; CORRELATION COEFFICIENT; DIAGNOSTIC ACCURACY; DIAGNOSTIC TEST ACCURACY STUDY; DISEASE CLASSIFICATION; DRUG INDUCED DISEASE; DRUG INDUCED LONG QT SYNDROME; ELECTROCARDIOGRAPHY; FEMALE; HEART REPOLARIZATION; HOLTER MONITOR; HOLTER MONITORING; HUMAN; LONG QT SYNDROME; MAJOR CLINICAL STUDY; MALE; QT INTERVAL; RANDOMIZED CONTROLLED TRIAL; ROOT MEAN SQUARE ELECTROCARDIOGRAPHY; SCHOOL CHILD; SCINTISCANNING; SIGNAL NOISE RATIO; SINGLE DRUG DOSE; SPIKE WAVE; T WAVE; VERY ELDERLY;

ADOLESCENT; ADULT; CARDIOTONIC AGENTS; CASE-CONTROL STUDIES; CHILD; CHILD, PRESCHOOL; DATA INTERPRETATION, STATISTICAL; ELECTROCARDIOGRAPHY, AMBULATORY; FEMALE; FLUOROQUINOLONES; HEART RATE; HUMANS; LONG QT SYNDROME; MALE; MIDDLE AGED; RANDOMIZED CONTROLLED TRIALS AS TOPIC; YOUNG ADULT;

EID: 84898652694     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0085689     Document Type: Article

References (17)

1. Lux RL, Gettes LS, Mason JW (2006) Understanding proarrhythmic potential in therapeutic drug development: alternate strategies for measuring and tracking repolarization. Jour (Pubitemid 44465944)
2. Fuller MS, Sandor G, Punske B, Taccardi B, MacLeod RS, et al. (2000) Estimates of repolarization dispersion from electrocardiographic measurements. Circulation 102:685-691. (Pubitemid 30640670)
3. Fuller MS, Sandor G, Punske B, Taccardi B, MacLeod RS, et al. (2000) Estimates of repolarization and its dispersion from electrocardiographic measurements: direct epicardial assessment in the canine heart. J Electrocardiol 33:171-180. (Pubitemid 30257788)
4. Haws CW, Lux RL (1990) Correlation between in vivo transmembrane action potential durations and activation-recovery intervals from electrograms. Effects of interventions that alter repolarization time. Circulation 81:281-288. (Pubitemid 20031792)
5. Lux RL, Fuller MS, MacLeod RS, Ershler PR, Punske BB, et al. (1999) Noninvasive indices of repolarization and its dispersion. J Electrocardiol 32 Suppl: 153-157. (Pubitemid 30100121)
6. Couderc JP (2010) The telemetric and Holter ECG warehouse initiative (THEW): a data repository for the design, implementation and validation of ECG-related technologies. Conference proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society IEEE Engineering in Medicine and Biology Society Conference 2010:6252-6255.
7. Couderc JP, Garnett C, Li M, Handzel R, McNitt S, et al. (2011) Highly automated QT measurement techniques in 7 thorough QT studies implemented under ICH E14 guidelines. Annals of noninvasive electrocardiology: the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc 16:13-24.
8. Darpo B, Fossa AA, Couderc JP, Zhou M, Schreyer A, et al. (2011) Improving the precision of QT measurements. Cardiology journal 18:401-410.
9. Holzgrefe HH, Jr., Ferber G, Morrison R, Meyer O, Greiter-Wilke A, et al. (2011) Characterization of the Human QT Interval: Novel Distribution-Based Assessment of the Repolarization Effects of Moxifloxacin. Journal of clinical pharmacology.
10. Bland JM, Altman DG (1999) Measuring agreement in method comparison studies. Stat Methods Med Res 8:135-160. (Pubitemid 29425900)
11. Akoum NW, Wasmund SL, Lux RL, Hamdan MH (2010) Reverse electrical remodeling of the ventricles following successful restoration of sinus rhythm in patients with persistent atrial fibrillation. Pacing and clinical electrophysiology: PACE 33:1198-1202.
12. Segerson NM, Litwin SE, Daccarett M, Wall TS, Hamdan MH, et al. (2008) Scatter in repolarization timing predicts clinical events in post-myocardial infarction patients. Heart rhythm: the official journal of the Heart Rhythm Society 5:208-214.
13. Malik M, Farbom P, Batchvarov V, Hnatkova K, Camm AJ (2002) Relation between QT and RR intervals is highly individual among healthy subjects: implications for heart rate correction of the QT interval. Heart 87:220-228. (Pubitemid 34177674)
14. Malik M, Hnatkova K, Schmidt A, Smetana P (2009) Correction for QT/RR hysteresis in the assessment of drug-induced QTc changes-cardiac safety of gadobutrol. Annals of noninvasive electrocardiology: the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc 14:242-250.
15. Kang J, Wang L, Chen XL, Triggle DJ, Rampe D (2001) Interactions of a series of fluoroquinolone antibacterial drugs with the human cardiac K+ channel HERG. Molecular pharmacology 59:122-126. (Pubitemid 32043093)
16. Sanguinetti MC, Jiang C, Curran ME, Keating MT (1995) A mechanistic link between an inherited and an acquired cardiac arrhythmia: HERG encodes the IKr potassium channel. Cell 81:299-307.
17. Trudeau M, Warmke JW, Ganetzky B, Robertson GA (1995) HERG, A human inward rectifier in the voltage-gated potassium channel family. Science 269:92-95.