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Volumn 9, Issue 1, 2014, Pages

Tumor-specific hypermethylation of epigenetic biomarkers, including SFRP1, predicts for poorer survival in patients from the TCGA kidney renal clear cell carcinoma (KIRC) project

Author keywords

[No Author keywords available]

Indexed keywords

BASONUCLIN 1; BIOLOGICAL MARKER; FIBRILLIN 2; SECRETED FRIZZLED RELATED PROTEIN 1; UNCLASSIFIED DRUG; WNT PROTEIN;

EID: 84898629861     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0085621     Document Type: Article
Times cited : (53)

References (48)
  • 1
    • 33847638137 scopus 로고    scopus 로고
    • Estimates of the cancer incidence and mortality in Europe in 2006
    • DOI 10.1093/annonc/mdl498
    • Ferlay J, Autier P, Boniol M, Heanue M, Colombet M, et al. (2007) Estimates of the cancer incidence and mortality in Europe in 2006. Ann Oncol 18: 581-592 (Pubitemid 46359643)
    • (2007) Annals of Oncology , vol.18 , Issue.3 , pp. 581-592
    • Ferlay, J.1    Autier, P.2    Boniol, M.3    Heanue, M.4    Colombet, M.5    Boyle, P.6
  • 2
  • 3
    • 0028587585 scopus 로고
    • Somatic mutations of the von hippel-lindau disease tumour suppressor gene in nonfamilial clear cell renal carcinoma
    • Foster K, Prowse A, van den Berg A, Fleming S, Hulsbeek MMF, et al. (1994) Somatic mutations of the von hippel-lindau disease tumour suppressor gene in nonfamilial clear cell renal carcinoma. Hum Mol Genet 3: 2169-2173
    • (1994) Hum Mol Genet , vol.3 , pp. 2169-2173
    • Foster, K.1    Prowse, A.2    Van Den Berg, A.3    Fleming, S.4    Hulsbeek, M.M.F.5
  • 6
    • 84879890360 scopus 로고    scopus 로고
    • The cancer genome altas research network
    • Comprehensive molecular characterization of clear cell renal cell carcinoma
    • The Cancer Genome Altas Research Network (2013) Comprehensive molecular characterization of clear cell renal cell carcinoma. Nature 499: 43-49
    • (2013) Nature , vol.499 , pp. 43-49
  • 7
    • 79251635938 scopus 로고    scopus 로고
    • Exome sequencing identifies frequent mutation of the SWI/SNF complex gene PBRM1 in renal carcinoma
    • Varela I, Tarpey P, Raine K, Huang D, Ong CK, et al. (2011) Exome sequencing identifies frequent mutation of the SWI/SNF complex gene PBRM1 in renal carcinoma. Nature 469: 539-542
    • (2011) Nature , vol.469 , pp. 539-542
    • Varela, I.1    Tarpey, P.2    Raine, K.3    Huang, D.4    Ong, C.K.5
  • 8
    • 84655176646 scopus 로고    scopus 로고
    • Frequent mutations of genes encoding ubiquitin-mediated proteolysis pathway components in clear cell renal cell carcinoma
    • Guo G, Gui Y, Gao S, Tang A, Hu X, et al. (2012) Frequent mutations of genes encoding ubiquitin-mediated proteolysis pathway components in clear cell renal cell carcinoma. Nat Genet 44: 17-19
    • (2012) Nat Genet , vol.44 , pp. 17-19
    • Guo, G.1    Gui, Y.2    Gao, S.3    Tang, A.4    Hu, X.5
  • 9
    • 75149188170 scopus 로고    scopus 로고
    • Systematic sequencing of renal carcinoma reveals inactivation of histone modifying genes
    • Dalgliesh GL, Furge K, Greenman C, Chen L, Bignell G, et al. (2010) Systematic sequencing of renal carcinoma reveals inactivation of histone modifying genes. Nature 463: 360-363
    • (2010) Nature , vol.463 , pp. 360-363
    • Dalgliesh, G.L.1    Furge, K.2    Greenman, C.3    Chen, L.4    Bignell, G.5
  • 10
    • 84880967722 scopus 로고    scopus 로고
    • Integrated molecular analysis of clear-cell renal cell carcinoma
    • Sato Y, Yoshizato T, Shiraishi Y, Maekawa S, Okuno Y, et al. (2013) Integrated molecular analysis of clear-cell renal cell carcinoma. Nat Genet 45: 860-867
    • (2013) Nat Genet , vol.45 , pp. 860-867
    • Sato, Y.1    Yoshizato, T.2    Shiraishi, Y.3    Maekawa, S.4    Okuno, Y.5
  • 11
    • 78751681420 scopus 로고    scopus 로고
    • Epigenetics of renal cell carcinoma: The path towards new diagnostics and therapeutics
    • Morris MR, Maher ER (2010) Epigenetics of renal cell carcinoma: the path towards new diagnostics and therapeutics. Genome Med 2: 59
    • (2010) Genome Med , vol.2 , pp. 59
    • Morris, M.R.1    Maher, E.R.2
  • 12
    • 33644510421 scopus 로고    scopus 로고
    • Genetic and epigenetic analysis of von hippel-lindau (vhl) gene alterations and relationship with clinical variables in sporadic renal cancer
    • Banks RE, Tirukonda P, Taylor C, Hornigold N, Astuti D, et al. (2006) Genetic and epigenetic analysis of von Hippel-Lindau (VHL) gene alterations and relationship with clinical variables in sporadic renal cancer. Cancer Res 66: 2000-2011
    • (2006) Cancer Res , vol.66 , pp. 2000-2011
    • Banks, R.E.1    Tirukonda, P.2    Taylor, C.3    Hornigold, N.4    Astuti, D.5
  • 15
    • 36148946432 scopus 로고    scopus 로고
    • Evaluation of the 3p21.3 tumour-suppressor gene cluster
    • DOI 10.1038/sj.onc.1210547, PII 1210547
    • Hesson LB, Cooper WN, Latif F (2007) Evaluation of the 3p21.3 tumoursuppressor gene cluster. Oncogene 26: 7283-7301 (Pubitemid 350115980)
    • (2007) Oncogene , vol.26 , Issue.52 , pp. 7283-7301
    • Hesson, L.B.1    Cooper, W.N.2    Latif, F.3
  • 16
    • 77950859659 scopus 로고    scopus 로고
    • Identification of candidate tumour suppressor genes frequently methylated in renal cell carcinoma
    • Morris MR, Ricketts C, Gentle D, Abdulrahman M, Clarke N, et al. (2010) Identification of candidate tumour suppressor genes frequently methylated in renal cell carcinoma. Oncogene 29: 2104-2117
    • (2010) Oncogene , vol.29 , pp. 2104-2117
    • Morris, M.R.1    Ricketts, C.2    Gentle, D.3    Abdulrahman, M.4    Clarke, N.5
  • 17
    • 79953062931 scopus 로고    scopus 로고
    • Genomewide methylation analysis identifies epigenetically inactivated candidate tumour suppressor genes in renal cell carcinoma
    • Morris MR, Ricketts CJ, Gentle D, McRonald F, Carli N, et al. (2011) Genomewide methylation analysis identifies epigenetically inactivated candidate tumour suppressor genes in renal cell carcinoma. Oncogene 30: 1390-1401
    • (2011) Oncogene , vol.30 , pp. 1390-1401
    • Morris, M.R.1    Ricketts, C.J.2    Gentle, D.3    McRonald, F.4    Carli, N.5
  • 18
    • 67749113811 scopus 로고    scopus 로고
    • CpG methylation profiling in VHL related and VHL unrelated renal cell carcinoma
    • McRonald FE, Morris MR, Gentle D, Winchester L, Baban D, et al. (2009) CpG methylation profiling in VHL related and VHL unrelated renal cell carcinoma. Mol Cancer 8: 31
    • (2009) Mol Cancer , vol.8 , pp. 31
    • McRonald, F.E.1    Morris, M.R.2    Gentle, D.3    Winchester, L.4    Baban, D.5
  • 19
    • 84863409800 scopus 로고    scopus 로고
    • Genomewide cpg island methylation analysis implicates novel genes in the pathogenesis of renal cell carcinoma
    • Ricketts CJ, Morris MR, Gentle D, Brown M, Wake N, et al. (2012) Genomewide CpG island methylation analysis implicates novel genes in the pathogenesis of renal cell carcinoma. Epigenetics 7: 278-290
    • (2012) Epigenetics , vol.7 , pp. 278-290
    • Ricketts, C.J.1    Morris, M.R.2    Gentle, D.3    Brown, M.4    Wake, N.5
  • 20
    • 84879466482 scopus 로고    scopus 로고
    • Adverse outcomes in clear cell renal cell carcinoma with mutations of 3p21 epigenetic regulators bap1 and setd2: A report by mskcc and the kirc tcga research network
    • Hakimi AA, Ostrovnaya I, Reva B, Schultz N, Chen YB, et al. (2013) Adverse Outcomes in Clear Cell Renal Cell Carcinoma with Mutations of 3p21 Epigenetic Regulators BAP1 and SETD2: A Report by MSKCC and the KIRC TCGA Research Network. Clin Cancer Res 19: 3259-3267
    • (2013) Clin Cancer Res , vol.19 , pp. 3259-3267
    • Hakimi, A.A.1    Ostrovnaya, I.2    Reva, B.3    Schultz, N.4    Chen, Y.B.5
  • 21
    • 84869487977 scopus 로고    scopus 로고
    • Loss of PBRM1 expression is associated with renal cell carcinoma progression
    • Pawlowski R, Muhl SM, Sulser T, Krek W, Moch H, et al. (2013) Loss of PBRM1 expression is associated with renal cell carcinoma progression. Int J Cancer 132: E11-E17
    • (2013) Int J Cancer , vol.132
    • Pawlowski, R.1    Muhl, S.M.2    Sulser, T.3    Krek, W.4    Moch, H.5
  • 22
    • 69449084444 scopus 로고    scopus 로고
    • The relationship of DNA methylation with age, gender and genotype in twins and healthy controls
    • Boks MP, Derks EM, Weisenberger DJ, Strengman E, Janson E, et al. (2009) The relationship of DNA methylation with age, gender and genotype in twins and healthy controls. PLoS One 4: e6767
    • (2009) Plos One , vol.4
    • Boks, M.P.1    Derks, E.M.2    Weisenberger, D.J.3    Strengman, E.4    Janson, E.5
  • 23
    • 84860595187 scopus 로고    scopus 로고
    • Gata5 cpg island methylation in renal cell cancer: A potential biomarker for metastasis and disease progression
    • Peters I, Eggers H, Atschekzei F, Hennenlotter J, Waalkes S, et al. (2012) GATA5 CpG island methylation in renal cell cancer: a potential biomarker for metastasis and disease progression. BJU Int 110: E144-E152
    • (2012) Bju Int , vol.110
    • Peters, I.1    Eggers, H.2    Atschekzei, F.3    Hennenlotter, J.4    Waalkes, S.5
  • 24
    • 76149118805 scopus 로고    scopus 로고
    • Prognostic significance of gremlin1 (grem1) promoter cpg island hypermethylation in clear cell renal cell carcinoma
    • van Vlodrop IJ, Baldewijns MM, Smits KM, Schouten LJ, van Neste L, et al. (2010) Prognostic significance of Gremlin1 (GREM1) promoter CpG island hypermethylation in clear cell renal cell carcinoma. Am J Pathol 176: 575-584
    • (2010) Am J Pathol , vol.176 , pp. 575-584
    • Van Vlodrop, I.J.1    Baldewijns, M.M.2    Smits, K.M.3    Schouten, L.J.4    Van Neste, L.5
  • 26
    • 67449100578 scopus 로고    scopus 로고
    • Methylation of CLDN6, FBN2, RBP1, RBP4, TFPI2, and TMEFF2 in esophageal squamous cell carcinoma
    • Tsunoda S, Smith E, De Young NJ, Wang X, Tian ZQ, et al. (2009) Methylation of CLDN6, FBN2, RBP1, RBP4, TFPI2, and TMEFF2 in esophageal squamous cell carcinoma. Oncol Rep 21: 1067-1073
    • (2009) Oncol Rep , vol.21 , pp. 1067-1073
    • Tsunoda, S.1    Smith, E.2    De Young, N.J.3    Wang, X.4    Tian, Z.Q.5
  • 27
    • 84867813233 scopus 로고    scopus 로고
    • FBN2 methylation is detected in the serum of colorectal cancer patients with hepatic metastasis
    • Hibi K, Mizukami H, Saito M, Kigawa G, Nemoto H, et al. (2012) FBN2 methylation is detected in the serum of colorectal cancer patients with hepatic metastasis. Anticancer Res 32: 4371-4374
    • (2012) Anticancer Res , vol.32 , pp. 4371-4374
    • Hibi, K.1    Mizukami, H.2    Saito, M.3    Kigawa, G.4    Nemoto, H.5
  • 29
    • 77956525903 scopus 로고    scopus 로고
    • Genomewide DNA methylation analysis reveals novel targets for drug development in mantle cell lymphoma
    • Leshchenko VV, Kuo PY, Shaknovich R, Yang DT, Gellen T, et al. (2010) Genomewide DNA methylation analysis reveals novel targets for drug development in mantle cell lymphoma. Blood 116: 1025-1034
    • (2010) Blood , vol.116 , pp. 1025-1034
    • Leshchenko, V.V.1    Kuo, P.Y.2    Shaknovich, R.3    Yang, D.T.4    Gellen, T.5
  • 30
    • 49149121975 scopus 로고    scopus 로고
    • PCDH8, the human homolog of PAPC, is a candidate tumor suppressor of breast cancer
    • Yu JS, Koujak S, Nagase S, Li CM, Su T, et al. (2008) PCDH8, the human homolog of PAPC, is a candidate tumor suppressor of breast cancer. Oncogene 27: 4657-4665
    • (2008) Oncogene , vol.27 , pp. 4657-4665
    • Yu, J.S.1    Koujak, S.2    Nagase, S.3    Li, C.M.4    Su, T.5
  • 31
    • 84866450351 scopus 로고    scopus 로고
    • Frequent silencing of protocadherin 8 by promoter methylation, a candidate tumor suppressor for human gastric cancer
    • Zhang D, Zhao W, Liao X, Bi T, Li H, et al. (2012) Frequent silencing of protocadherin 8 by promoter methylation, a candidate tumor suppressor for human gastric cancer. Oncol Rep 28: 1785-1791
    • (2012) Oncol Rep , vol.28 , pp. 1785-1791
    • Zhang, D.1    Zhao, W.2    Liao, X.3    Bi, T.4    Li, H.5
  • 32
    • 56749176437 scopus 로고    scopus 로고
    • Cadherins and cancer: How does cadherin dysfunction promote tumor progression?
    • Jeanes A, Gottardi CJ, Yap AS (2008) Cadherins and cancer: how does cadherin dysfunction promote tumor progression? Oncogene 27: 6920-6929
    • (2008) Oncogene , vol.27 , pp. 6920-6929
    • Jeanes, A.1    Gottardi, C.J.2    Yap, A.S.3
  • 33
    • 77953947951 scopus 로고    scopus 로고
    • Frequent silencing of protocadherin 17, a candidate tumour suppressor for esophageal squamous cell carcinoma
    • Haruki S, Imoto I, Kozaki K, Matsui T, Kawachi H, et al. (2010) Frequent silencing of protocadherin 17, a candidate tumour suppressor for esophageal squamous cell carcinoma. Carcinogenesis 31: 1027-1036
    • (2010) Carcinogenesis , vol.31 , pp. 1027-1036
    • Haruki, S.1    Imoto, I.2    Kozaki, K.3    Matsui, T.4    Kawachi, H.5
  • 34
    • 33646422462 scopus 로고    scopus 로고
    • Frequent silencing of the candidate tumor suppressor PCDH20 by epigenetic mechanism in non-small-cell lung cancers
    • Imoto I, Izumi H, Yokoi S, Hosoda H, Shibata T, et al. (2006) Frequent silencing of the candidate tumor suppressor PCDH20 by epigenetic mechanism in non-small-cell lung cancers. Cancer Res 66: 4617-4626
    • (2006) Cancer Res , vol.66 , pp. 4617-4626
    • Imoto, I.1    Izumi, H.2    Yokoi, S.3    Hosoda, H.4    Shibata, T.5
  • 35
    • 33845926895 scopus 로고    scopus 로고
    • A genome-wide screen for promoter methylation in lung cancer identifies novel methylation markers for multiple malignancies
    • Shames DS, Girard L, Gao B, Sato M, Lewis CM, et al. (2006) A genome-wide screen for promoter methylation in lung cancer identifies novel methylation markers for multiple malignancies. PLoS Med 3: e486
    • (2006) Plos Med , vol.3
    • Shames, D.S.1    Girard, L.2    Gao, B.3    Sato, M.4    Lewis, C.M.5
  • 37
    • 77957370748 scopus 로고    scopus 로고
    • Genomewide DNA methylation profiling of chronic lymphocytic leukemia allows identification of epigenetically repressed molecular pathways with clinical impact
    • Tong WG, Wierda WG, Lin E, Kuang SQ, Bekele BN, et al. (2010) Genomewide DNA methylation profiling of chronic lymphocytic leukemia allows identification of epigenetically repressed molecular pathways with clinical impact. Epigenetics 5: 499-508
    • (2010) Epigenetics , vol.5 , pp. 499-508
    • Tong, W.G.1    Wierda, W.G.2    Lin, E.3    Kuang, S.Q.4    Bekele, B.N.5
  • 38
    • 84861335163 scopus 로고    scopus 로고
    • P63 transcriptionally regulates bnc1, a pol i and pol ii transcription factor that regulates ribosomal biogenesis and epithelial differentiation
    • Boldrup L, Coates PJ, Laurell G, Nylander K (2012) p63 Transcriptionally regulates BNC1, a Pol I and Pol II transcription factor that regulates ribosomal biogenesis and epithelial differentiation. Eur J Cancer 48: 1401-1406
    • (2012) Eur J Cancer , vol.48 , pp. 1401-1406
    • Boldrup, L.1    Coates, P.J.2    Laurell, G.3    Nylander, K.4
  • 41
    • 58149354782 scopus 로고    scopus 로고
    • Methylationassociated silencing of SFRP1 in renal cell carcinoma
    • Awakura Y, Nakamura E, Ito N, Kamoto T, Ogawa O (2008) Methylationassociated silencing of SFRP1 in renal cell carcinoma. Oncol Rep 20: 1257-1263
    • (2008) Oncol Rep , vol.20 , pp. 1257-1263
    • Awakura, Y.1    Nakamura, E.2    Ito, N.3    Kamoto, T.4    Ogawa, O.5
  • 42
    • 34547107319 scopus 로고    scopus 로고
    • WNT signaling pathway and stem cell signaling network
    • DOI 10.1158/1078-0432.CCR-06-2316
    • Katoh M, Katoh M (2007) WNT signaling pathway and stem cell signaling network. Clin Cancer Res 13: 4042-4045 (Pubitemid 47105963)
    • (2007) Clinical Cancer Research , vol.13 , Issue.14 , pp. 4042-4045
    • Katoh, M.1    Katoh, M.2
  • 43
    • 70349456794 scopus 로고    scopus 로고
    • Wnt antagonist gene DKK2 is epigenetically silenced and inhibits renal cancer progression through apoptotic and cell cycle pathways
    • Hirata H, Hinoda Y, Nakajima K, Kawamoto K, Kikuno N, et al. (2009) Wnt antagonist gene DKK2 is epigenetically silenced and inhibits renal cancer progression through apoptotic and cell cycle pathways. Clin Cancer Res 15: 5678-5687
    • (2009) Clin Cancer Res , vol.15 , pp. 5678-5687
    • Hirata, H.1    Hinoda, Y.2    Nakajima, K.3    Kawamoto, K.4    Kikuno, N.5
  • 45
    • 79951986031 scopus 로고    scopus 로고
    • Wnt antagonist DKK1 acts as a tumor suppressor gene that induces apoptosis and inhibits proliferation in human renal cell carcinoma
    • Hirata H, Hinoda Y, Nakajima K, Kawamoto K, Kikuno N, et al. (2011) Wnt antagonist DKK1 acts as a tumor suppressor gene that induces apoptosis and inhibits proliferation in human renal cell carcinoma. Int J Cancer 128: 1793- 1803.
    • (2011) Int J Cancer , vol.128 , pp. 1793-1803
    • Hirata, H.1    Hinoda, Y.2    Nakajima, K.3    Kawamoto, K.4    Kikuno, N.5
  • 46
    • 78649872309 scopus 로고    scopus 로고
    • Secreted frizzled-related protein-5 is epigenetically downregulated and functions as a tumor suppressor in kidney cancer
    • Kawakami K, Yamamura S, Hirata H, Ueno K, Saini S, et al. (2011) Secreted frizzled-related protein-5 is epigenetically downregulated and functions as a tumor suppressor in kidney cancer. Int J Cancer 128: 541-550
    • (2011) Int J Cancer , vol.128 , pp. 541-550
    • Kawakami, K.1    Yamamura, S.2    Hirata, H.3    Ueno, K.4    Saini, S.5
  • 47
    • 46049102805 scopus 로고    scopus 로고
    • DNA methylation and histone modifications cause silencing of Wnt antagonist gene in human renal cell carcinoma cell lines
    • DOI 10.1002/ijc.23514
    • Kawamoto K, Hirata H, Kikuno N, Tanaka Y, Nakagawa M, et al. (2008) DNA methylation and histone modifications cause silencing of Wnt antagonist gene in human renal cell carcinoma cell lines. Int J Cancer 123: 535-542 (Pubitemid 351898410)
    • (2008) International Journal of Cancer , vol.123 , Issue.3 , pp. 535-542
    • Kawamoto, K.1    Hirata, H.2    Kikuno, N.3    Tanaka, Y.4    Nakagawa, M.5    Dahiya, R.6
  • 48
    • 84867411516 scopus 로고    scopus 로고
    • Reexpression of tumor suppressor, sFRP1, leads to antitumor synergy of combined HDAC and methyltransferase inhibitors in chemoresistant cancers
    • Cooper SJ, von Roemeling CA, Kang KH, Marlow LA, Grebe SK, et al. (2012) Reexpression of tumor suppressor, sFRP1, leads to antitumor synergy of combined HDAC and methyltransferase inhibitors in chemoresistant cancers. Mol Cancer Ther 11: 2105-2115
    • (2012) Mol Cancer Ther , vol.11 , pp. 2105-2115
    • Cooper, S.J.1    Von Roemeling, C.A.2    Kang, K.H.3    Marlow, L.A.4    Grebe, S.K.5


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