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Volumn 33, Issue 3, 2014, Pages 225-234

Cox-2, EGFR, and ERBB-2 expression in cervical intraepithelial neoplasia and cervical cancer using an automated imaging system

Author keywords

Cervical intraepithelial neoplasia; Cyclooxygenase 2; EGFR; ERBB 2; Uterine cervical neoplasm

Indexed keywords

CYCLOOXYGENASE 2; EPIDERMAL GROWTH FACTOR RECEPTOR 2; VASCULOTROPIN; EGFR PROTEIN, HUMAN; EPIDERMAL GROWTH FACTOR RECEPTOR; PTGS2 PROTEIN, HUMAN; TUMOR MARKER;

EID: 84898597787     PISSN: 02771691     EISSN: 15387151     Source Type: Journal    
DOI: 10.1097/PGP.0b013e318290405a     Document Type: Article
Times cited : (27)

References (66)
  • 2
    • 78049528352 scopus 로고    scopus 로고
    • Human papillomavirus genotype attribution in invasive cervical cancer: A retrospective cross-sectional worldwide study
    • Retrospective International Survey and HPV Time Trends Study Group
    • de Sanjose S, Quint WG, Alemany L, et al. Retrospective International Survey and HPV Time Trends Study Group. Human papillomavirus genotype attribution in invasive cervical cancer: a retrospective cross-sectional worldwide study. Lancet Oncol 2010;11:1048-56.
    • (2010) Lancet Oncol , vol.11 , pp. 1048-1056
    • De Sanjose, S.1    Quint, W.G.2    Alemany, L.3
  • 3
    • 0032840918 scopus 로고    scopus 로고
    • Human papillomavirus is a necessary cause of invasive cervical cancer worldwide
    • Walboomers JM, Jacobs MV, Manos MM, et al. Human papillomavirus is a necessary cause of invasive cervical cancer worldwide. J Pathol 1999;189:12-9.
    • (1999) J Pathol , vol.189 , pp. 12-19
    • Walboomers, J.M.1    Jacobs, M.V.2    Manos, M.M.3
  • 4
    • 0037421589 scopus 로고    scopus 로고
    • Epidemiologic classification of human papillomavirus types associated with cervical cancer
    • Munoz N, Bosch FX, de Sanjose S, et al. Epidemiologic classification of human papillomavirus types associated with cervical cancer. N Engl J Med 2003;348:518-27.
    • (2003) N Engl J Med , vol.348 , pp. 518-527
    • Munoz, N.1    Bosch, F.X.2    De Sanjose, S.3
  • 6
    • 64849105830 scopus 로고    scopus 로고
    • A review of human carcinogens-part B: Biological agents
    • Bouvard V, Baan R, Straif K, et al. A review of human carcinogens-part B: biological agents. Lancet Oncol 2009; 10:321-22.
    • (2009) Lancet Oncol , vol.10 , pp. 321-322
    • Bouvard, V.1    Baan, R.2    Straif, K.3
  • 7
    • 0035956499 scopus 로고    scopus 로고
    • Persistent human papillomavirus infection as a predictor of cervical intra-epithelial neoplasia
    • Schlecht NF, Kulaga S, Robitaille J, et al. Persistent human papillomavirus infection as a predictor of cervical intra-epithelial neoplasia. JAMA 2001;286:3106-14.
    • (2001) JAMA , vol.286 , pp. 3106-3114
    • Schlecht, N.F.1    Kulaga, S.2    Robitaille, J.3
  • 10
    • 1842471336 scopus 로고    scopus 로고
    • Signaling through the epidermal growth factor receptor during the development of malignancy
    • Grandis JR, Sok JC. Signaling through the epidermal growth factor receptor during the development of malignancy. Pharmacol Ther 2004;102:37-46.
    • (2004) Pharmacol Ther , vol.102 , pp. 37-46
    • Grandis, J.R.1    Sok, J.C.2
  • 11
    • 0030817148 scopus 로고    scopus 로고
    • Expression of epidermal growth factor receptor and human papillomavirus E6/E7 proteins in cervical carcinoma cells
    • Hu G, Liu W, Mendelsohn J, et al. Expression of epidermal growth factor receptor and human papillomavirus E6/E7 proteins in cervical carcinoma cells. J Natl Cancer Inst 1997;89:1271-6.
    • (1997) J Natl Cancer Inst , vol.89 , pp. 1271-1276
    • Hu, G.1    Liu, W.2    Mendelsohn, J.3
  • 12
    • 0035328577 scopus 로고    scopus 로고
    • Human Papillomavirus type 16 E6 and E7 cooperate to increase epidermal growth factor receptor (EGFR) mRNA levels, overcoming mechanisms by which excessive EGFR signaling shortens the life span of normal human keratinocytes
    • Akerman GS, Tolleson WH, Brown KL, et al. Human Papillomavirus type 16 E6 and E7 cooperate to increase epidermal growth factor receptor (EGFR) mRNA levels, overcoming mechanisms by which excessive EGFR signaling shortens the life span of normal human keratinocytes. Cancer Res 2001;61:3837-43.
    • (2001) Cancer Res , vol.61 , pp. 3837-3843
    • Akerman, G.S.1    Tolleson, W.H.2    Brown, K.L.3
  • 13
    • 0034662650 scopus 로고    scopus 로고
    • Targeted disruption of the epidermal growth factor receptor inhibits development of papillomas and carcinomas from human papillomavirus-immortalized kerotinocytes
    • Woodworth CD, Gaiotti D, Michael E, et al. Targeted disruption of the epidermal growth factor receptor inhibits development of papillomas and carcinomas from human papillomavirus-immortalized kerotinocytes. Cancer Res 2000;60:4397-402.
    • (2000) Cancer Res , vol.60 , pp. 4397-4402
    • Woodworth, C.D.1    Gaiotti, D.2    Michael, E.3
  • 14
    • 34249883352 scopus 로고    scopus 로고
    • A critical role for D-type cyclins in cellular transformation induces by E6/E7 of human papillomavirus type 16 and E6/E7/ErbB-2 cooperation
    • Yasmeen A, Hosein AN, Yu Q, et al. A critical role for D-type cyclins in cellular transformation induces by E6/E7 of human papillomavirus type 16 and E6/E7/ErbB-2 cooperation. Cancer Sci 2007;1-5.
    • (2007) Cancer Sci , pp. 1-5
    • Yasmeen, A.1    Hosein, A.N.2    Yu, Q.3
  • 15
    • 34248393855 scopus 로고    scopus 로고
    • HPV16 E6-mediated stabilization of ErbB2 in neoplastic transformation of human cervical keratinocytes
    • Narisawa-Saito M, Handa K, Yugawa T, et al. HPV16 E6-mediated stabilization of ErbB2 in neoplastic transformation of human cervical keratinocytes. Oncogene 2007;26:2988-96.
    • (2007) Oncogene , vol.26 , pp. 2988-2996
    • Narisawa-Saito, M.1    Handa, K.2    Yugawa, T.3
  • 16
    • 34547854801 scopus 로고    scopus 로고
    • The oncogene HER2: It's signaling and transforming functions and its role in human cancer pathogenesis
    • Moasser MM. The oncogene HER2: it's signaling and transforming functions and its role in human cancer pathogenesis. Oncogene 2007;26:6469-87.
    • (2007) Oncogene , vol.26 , pp. 6469-6487
    • Moasser, M.M.1
  • 17
    • 13744254574 scopus 로고    scopus 로고
    • Cyclooxygenase-2 and epidermal growth factor receptor: Pharmacologic targets for chemoprevention
    • Dannenberg AJ, Lippman SM, Mann JR, et al. Cyclooxygenase-2 and epidermal growth factor receptor: pharmacologic targets for chemoprevention. J Clin Oncol 2005;23:254-64.
    • (2005) J Clin Oncol , vol.23 , pp. 254-264
    • Dannenberg, A.J.1    Lippman, S.M.2    Mann, J.R.3
  • 18
    • 68149183615 scopus 로고    scopus 로고
    • Biotin-free systems provide stronger immunohistochemical signal in oestrogen receptor evaluation of breast cancer
    • Rocha RM, Miller K, Soares F, et al. Biotin-free systems provide stronger immunohistochemical signal in oestrogen receptor evaluation of breast cancer. J Clin Pathol 2009; 62:699-704.
    • (2009) J Clin Pathol , vol.62 , pp. 699-704
    • Rocha, R.M.1    Miller, K.2    Soares, F.3
  • 20
    • 77955801655 scopus 로고    scopus 로고
    • Expression of Bcl-2 family proteins and association with clinicopathological characteristics of oral squamous cell carcinoma
    • Coutinho-Camillo CM, Lourenço SV, Nishimoto IN, et al. Expression of Bcl-2 family proteins and association with clinicopathological characteristics of oral squamous cell carcinoma. Histopathology 2010;57:304-16.
    • (2010) Histopathology , vol.57 , pp. 304-316
    • Coutinho-Camillo, C.M.1    Lourenço, S.V.2    Nishimoto, I.N.3
  • 21
    • 0033822690 scopus 로고    scopus 로고
    • Reliable and sensitive analysis of occult bone marrow metastases using automated cellular imaging
    • Bauer KD, de la Torre-Bueno J, Diel IJ, et al. Reliable and sensitive analysis of occult bone marrow metastases using automated cellular imaging. Clin Cancer Res 2000;6:3552-9.
    • (2000) Clin Cancer Res , vol.6 , pp. 3552-3559
    • Bauer, K.D.1    De La Torre-Bueno, J.2    Diel, I.J.3
  • 22
    • 2042432852 scopus 로고    scopus 로고
    • Enhanced accuracy and reliability of HER-2/neu immunohistochemical scoring using digital microscopy
    • Bloom K, Harrington D. Enhanced accuracy and reliability of HER-2/neu immunohistochemical scoring using digital microscopy. Am J Clin Pathol 2004;121:620-30.
    • (2004) Am J Clin Pathol , vol.121 , pp. 620-630
    • Bloom, K.1    Harrington, D.2
  • 23
    • 0036221471 scopus 로고    scopus 로고
    • The causal relation between human papillomavirus and cervical cancer
    • Bosch FX, Lorincz A, Munoz N, et al. The causal relation between human papillomavirus and cervical cancer. J Clin Pathol 2002;55:244-65.
    • (2002) J Clin Pathol , vol.55 , pp. 244-265
    • Bosch, F.X.1    Lorincz, A.2    Munoz, N.3
  • 24
    • 0026738776 scopus 로고
    • A cohort study of the risk of cervical intraepithelial neoplasia grade 2 or 3 in relation to papillomavirus infection
    • Koutsky LA, Holmes KK, Critchlow CW, et al. A cohort study of the risk of cervical intraepithelial neoplasia grade 2 or 3 in relation to papillomavirus infection. N Engl J Med 1992;327:1272-8.
    • (1992) N Engl J Med , vol.327 , pp. 1272-1278
    • Koutsky, L.A.1    Holmes, K.K.2    Critchlow, C.W.3
  • 25
    • 0037077876 scopus 로고    scopus 로고
    • Type specific persistence of high-risk human papillomavirus (HPV) as indicator of high grade cervical squamous intraepithelial lesions in young women: Population based prospective follow up study
    • Kjaer SK, van den Brule AJ, Paull G, et al. Type specific persistence of high-risk human papillomavirus (HPV) as indicator of high grade cervical squamous intraepithelial lesions in young women: population based prospective follow up study. BMJ 2002;325:572-8.
    • (2002) BMJ , vol.325 , pp. 572-578
    • Kjaer, S.K.1    Van Den Brule, A.J.2    Paull, G.3
  • 26
    • 0037385666 scopus 로고    scopus 로고
    • Low and high risk CIN1 and 2 lesions: Prospective value of grade, HPV and Ki67 immunoquantitative variables
    • Kruse AJ, Baak JP, Janssen EA, et al. Low and high risk CIN1 and 2 lesions: prospective value of grade, HPV and Ki67 immunoquantitative variables. J Pathol 2003;199:462-70.
    • (2003) J Pathol , vol.199 , pp. 462-470
    • Kruse, A.J.1    Baak, J.P.2    Janssen, E.A.3
  • 27
    • 0036850358 scopus 로고    scopus 로고
    • New markers for cervical dysplasia to visualise the genomic chaos created by aberrant oncogenic papillomavirus infections
    • von Knebel Doeberitz M. New markers for cervical dysplasia to visualise the genomic chaos created by aberrant oncogenic papillomavirus infections. Eur J Cancer 2002;38:2229-42.
    • (2002) Eur J Cancer , vol.38 , pp. 2229-2242
    • Von Knebel Doeberitz, M.1
  • 28
    • 1642353195 scopus 로고    scopus 로고
    • Molecular markers for the prediction of progression of CIN lesions
    • Gray LJ, Herington CS. Molecular markers for the prediction of progression of CIN lesions. Int J Gynecol Pathol 2004;23:95-6.
    • (2004) Int J Gynecol Pathol , vol.23 , pp. 95-96
    • Gray, L.J.1    Herington, C.S.2
  • 29
    • 14644396135 scopus 로고    scopus 로고
    • Immunohistochemistry in assessment of molecular pathogenesis of cervical carcinogenesis
    • Syrjanen KJ. Immunohistochemistry in assessment of molecular pathogenesis of cervical carcinogenesis. Eur J Gynaecol Oncol 2005;26:118-24.
    • (2005) Eur J Gynaecol Oncol , vol.26 , pp. 118-124
    • Syrjanen, K.J.1
  • 30
    • 4644304965 scopus 로고    scopus 로고
    • INK4A expression is related to grade of CIN and high-risk human papillomavirus but does not predict virus clearance after conization or disease outcome
    • INK4A expression is related to grade of CIN and high-risk human papillomavirus but does not predict virus clearance after conization or disease outcome. Int J Gynecol Pathol 2004;23:354-65.
    • (2004) Int J Gynecol Pathol , vol.23 , pp. 354-365
    • Branca, M.1    Ciotti, M.2    Santini, D.3
  • 31
    • 30444456078 scopus 로고    scopus 로고
    • Aberrant expression of vascular endothelial growth factor-C (VEGF-C) is related to grade of cervical intraepithelial neoplasia (CIN) and high-risk human papillomavirus (HPV), but does not predict virus clearance after treatment of CIN or prognosis of cervical cancer
    • Branca M, Giorgi C, Santini D, et al. Aberrant expression of vascular endothelial growth factor-C (VEGF-C) is related to grade of cervical intraepithelial neoplasia (CIN) and high-risk human papillomavirus (HPV), but does not predict virus clearance after treatment of CIN or prognosis of cervical cancer. J Clin Pathol 2006;59:40-7.
    • (2006) J Clin Pathol , vol.59 , pp. 40-47
    • Branca, M.1    Giorgi, C.2    Santini, D.3
  • 32
    • 33645835611 scopus 로고    scopus 로고
    • Down-regulation of nucleoside diphosphate (NDP) kinase nm23-H1 expression is unrelated to high-risk human papillomavirus (HPV) but associated with progression of CIN and unfavourable prognosis of cervical cancer
    • Branca M, Giorgi C, Ciotti M, et al. Down-regulation of nucleoside diphosphate (NDP) kinase nm23-H1 expression is unrelated to high-risk human papillomavirus (HPV) but associated with progression of CIN and unfavourable prognosis of cervical cancer. J Clin Pathol 2006;59:1044-51.
    • (2006) J Clin Pathol , vol.59 , pp. 1044-1051
    • Branca, M.1    Giorgi, C.2    Ciotti, M.3
  • 33
    • 33750466920 scopus 로고    scopus 로고
    • Over-expression of topoisomerase IIa is related to the grade of cervical intra-epithelial neoplasia (CIN) and high-risk human papillomavirus (HPV), but does not predict prognosis in cervical cancer or HPV clearance after cone treatment
    • Branca M, Giorgi C, Ciotti M, et al. Over-expression of topoisomerase IIa is related to the grade of cervical intra-epithelial neoplasia (CIN) and high-risk human papillomavirus (HPV), but does not predict prognosis in cervical cancer or HPV clearance after cone treatment. Int J Gynecol Pathol 2006;25:383-92.
    • (2006) Int J Gynecol Pathol , vol.25 , pp. 383-392
    • Branca, M.1    Giorgi, C.2    Ciotti, M.3
  • 34
    • 0034962509 scopus 로고    scopus 로고
    • INK4 are complimentary surrogate biomarkers for human papilloma virus-related cervical neoplasia
    • INK4 are complimentary surrogate biomarkers for human papilloma virus-related cervical neoplasia. Am J Surg Pathol 2001;25:884-91.
    • (2001) Am J Surg Pathol , vol.25 , pp. 884-891
    • Keating, J.T.1    Cviko, A.2    Riethdorf, S.3
  • 35
    • 1642297828 scopus 로고    scopus 로고
    • Quantitative molecular parameters to identify low-risk and high-risk early CIN lesions: Role of markers of proliferative activity and differentiation and Rb availability
    • Kruse AJ, Skaland I, Janssen EA, et al. Quantitative molecular parameters to identify low-risk and high-risk early CIN lesions: role of markers of proliferative activity and differentiation and Rb availability. Int J Gynecol Pathol 2004;23:100-9.
    • (2004) Int J Gynecol Pathol , vol.23 , pp. 100-109
    • Kruse, A.J.1    Skaland, I.2    Janssen, E.A.3
  • 36
    • 41349087575 scopus 로고    scopus 로고
    • Predicting high-risk human papillomavirus infection, progression of cervical intra-epithelial neoplasia, and prognosis of cervical cancer with a panel of 13 biomarkers tested in multivariate modeling
    • Branca M, Ciotti M, Giorgi C, et al. Predicting high-risk human papillomavirus infection, progression of cervical intra-epithelial neoplasia, and prognosis of cervical cancer with a panel of 13 biomarkers tested in multivariate modeling. Int J Gynecol Pathol 2008;27:265-73.
    • (2008) Int J Gynecol Pathol , vol.27 , pp. 265-273
    • Branca, M.1    Ciotti, M.2    Giorgi, C.3
  • 37
    • 34248578815 scopus 로고    scopus 로고
    • Cyclooxygenase-2 transcription in regulated by human papillomavirus 16 E6 and E7 oncoproteins: Evidence of a coexpressor/coactivator exchange
    • Subbaramaiah K, Dannenberg AJ. Cyclooxygenase-2 transcription in regulated by human papillomavirus 16 E6 and E7 oncoproteins: evidence of a coexpressor/coactivator exchange. Cancer Res 2007;67:3976-85.
    • (2007) Cancer Res , vol.67 , pp. 3976-3985
    • Subbaramaiah, K.1    Dannenberg, A.J.2
  • 38
    • 59449100165 scopus 로고    scopus 로고
    • High Expression of PGE2 enzymatic pathways in cervical (pre) neoplastic and functional consequences for antigen-presenting cells
    • Herfs M, Herman L, Hubert P, et al. High Expression of PGE2 enzymatic pathways in cervical (pre) neoplastic and functional consequences for antigen-presenting cells. Cancer Immunol Immunother 2009;58:603-14.
    • (2009) Cancer Immunol Immunother , vol.58 , pp. 603-614
    • Herfs, M.1    Herman, L.2    Hubert, P.3
  • 39
    • 0037386939 scopus 로고    scopus 로고
    • Combination of selective cyclooxygenase-2 inhibitor with epidermal growth factor receptor tyrosine kinase inhibitor ZD1839 and protein kinase a antisense causes cooperative antitumor and anti-angiogenic effect
    • Tortora G, Caputo R, Damiano V, et al. Combination of selective cyclooxygenase-2 inhibitor with epidermal growth factor receptor tyrosine kinase inhibitor ZD1839 and protein kinase a antisense causes cooperative antitumor and anti-angiogenic effect. Clin Cancer Res 2003;9:1566-72.
    • (2003) Clin Cancer Res , vol.9 , pp. 1566-1572
    • Tortora, G.1    Caputo, R.2    Damiano, V.3
  • 40
    • 19944432973 scopus 로고    scopus 로고
    • Levels of cyclo-oxygenase-2 are increased in oral mucosa of smokers: Evidence for the role of epidermal growth factor receptor and its ligands
    • Moraitis D, Du B, Lorenzo MS, et al. Levels of cyclo-oxygenase-2 are increased in oral mucosa of smokers: evidence for the role of epidermal growth factor receptor and its ligands. Cancer Res 2005;65:664-70.
    • (2005) Cancer Res , vol.65 , pp. 664-670
    • Moraitis, D.1    Du, B.2    Lorenzo, M.S.3
  • 41
    • 0842288955 scopus 로고    scopus 로고
    • Cyclooxygenase-2 expression predicts recurrence of cervical dysplasia following loop electrosurgical excision procedure
    • Farley J, Uyehara C, Hashiro G, et al. Cyclooxygenase-2 expression predicts recurrence of cervical dysplasia following loop electrosurgical excision procedure. Gynecol Oncol 2004;92:596-602.
    • (2004) Gynecol Oncol , vol.92 , pp. 596-602
    • Farley, J.1    Uyehara, C.2    Hashiro, G.3
  • 42
    • 33748462072 scopus 로고    scopus 로고
    • Expression of cyclooxigenase-2 (COX-2) and Ki67 as related to disease severity and HPV detection in squamous lesions of the cervix
    • Sarian LO, Derchain SF, Yoshida A, et al. Expression of cyclooxigenase-2 (COX-2) and Ki67 as related to disease severity and HPV detection in squamous lesions of the cervix. Gynecol Oncol 2006;102:537-541.
    • (2006) Gynecol Oncol , vol.102 , pp. 537-541
    • Sarian, L.O.1    Derchain, S.F.2    Yoshida, A.3
  • 43
    • 33846841081 scopus 로고    scopus 로고
    • Cyclooxygenase-2 expression in cervical intraepithelial neoplasia III and squ-amous cell cervical carcinoma, and its correlation with clinic pathologic variables
    • Dursun P, Yuce K, Usubutun A, et al. Cyclooxygenase-2 expression in cervical intraepithelial neoplasia III and squ-amous cell cervical carcinoma, and its correlation with clinic pathologic variables. Int Gynecol Cancer 2007;17:164-73.
    • (2007) Int Gynecol Cancer , vol.17 , pp. 164-173
    • Dursun, P.1    Yuce, K.2    Usubutun, A.3
  • 44
    • 18144426014 scopus 로고    scopus 로고
    • Cyclooxygenase-2 and c-erbB-2 expression in uterine cervical neoplasm assessed using tissue microarrays
    • Kim JY, Lim SJ, Park K, et al. Cyclooxygenase-2 and c-erbB-2 expression in uterine cervical neoplasm assessed using tissue microarrays. Gynecol Oncol 2005;97:337-41.
    • (2005) Gynecol Oncol , vol.97 , pp. 337-341
    • Kim, J.Y.1    Lim, S.J.2    Park, K.3
  • 45
    • 12144290754 scopus 로고    scopus 로고
    • Synchronous coexpression of epidermal growth factor receptor and cyclooxygenase-2 in carcinomas of the uterine cervix: A potential predictor of poor survival
    • Kim GE, Kim YB, Cho NH, et al. Synchronous coexpression of epidermal growth factor receptor and cyclooxygenase-2 in carcinomas of the uterine cervix: a potential predictor of poor survival. Clin Cancer Res 2004;10:1366-74.
    • (2004) Clin Cancer Res , vol.10 , pp. 1366-1374
    • Kim, G.E.1    Kim, Y.B.2    Cho, N.H.3
  • 46
    • 33745111782 scopus 로고    scopus 로고
    • COX-1 and COX-2 expression in stage i and II invasive cervical carcinoma: Relationship to disease relapse and long-term survival
    • Athavale R, Clooney K, O'Hagan J, et al. COX-1 and COX-2 expression in stage I and II invasive cervical carcinoma: relationship to disease relapse and long-term survival. Int J Gynecol Cancer 2006;16:1303-8.
    • (2006) Int J Gynecol Cancer , vol.16 , pp. 1303-1308
    • Athavale, R.1    Clooney, K.2    O'Hagan, J.3
  • 47
    • 31544462308 scopus 로고    scopus 로고
    • Expression of epidermal growth factors and their receptors in the bronchial of subjects with chronic obstructive pulmonary disease
    • Boer WI, Hau CH, Schadewijk A, et al. Expression of epidermal growth factors and their receptors in the bronchial of subjects with chronic obstructive pulmonary disease. Am J Clin Pathol 2006;125:184-92.
    • (2006) Am J Clin Pathol , vol.125 , pp. 184-192
    • Boer, W.I.1    Hau, C.H.2    Schadewijk, A.3
  • 48
    • 0026557152 scopus 로고
    • Immunohis-tochemical demonstration of elevated expression of epidermal growth factor receptor in neoplastic changes of cervical squamous epithelium
    • Maruo T, Yamasaki M, Ladines-Llave CA, et al. Immunohis-tochemical demonstration of elevated expression of epidermal growth factor receptor in neoplastic changes of cervical squamous epithelium. Cancer 1992;69:1182-7.
    • (1992) Cancer , vol.69 , pp. 1182-1187
    • Maruo, T.1    Yamasaki, M.2    Ladines-Llave, C.A.3
  • 49
    • 0034816985 scopus 로고    scopus 로고
    • Human papilloma virus (HPV)-E6/E7 and epidermal Growth factor receptor (EGF-R) protein levels in cervical cancer and cervical intraepithelial neoplasia (CIN)
    • Mathur SP, Mathur RS, Rust PF, et al. Human papilloma virus (HPV)-E6/E7 and epidermal Growth factor receptor (EGF-R) protein levels in cervical cancer and cervical intraepithelial neoplasia (CIN). Am J Reprod Immunol 2001;46:280-287.
    • (2001) Am J Reprod Immunol , vol.46 , pp. 280-287
    • Mathur, S.P.1    Mathur, R.S.2    Rust, P.F.3
  • 50
    • 0033042754 scopus 로고    scopus 로고
    • Oncogene alterations in carcinomas of the uterine cervix: Overexpression of the epidermal growth factor receptor is associated with poor prognosis
    • Kersemaekers AM, Fleuren GJ, Kenter GG, et al. Oncogene alterations in carcinomas of the uterine cervix: overexpression of the epidermal growth factor receptor is associated with poor prognosis. Clin Cancer Res 1999;5:577-586.
    • (1999) Clin Cancer Res , vol.5 , pp. 577-586
    • Kersemaekers, A.M.1    Fleuren, G.J.2    Kenter, G.G.3
  • 51
    • 0029954643 scopus 로고    scopus 로고
    • Evaluation of the prognostic significance of cathepsin D, epidermal growth factor receptor, and c-erbB-2 in early cervical squamous cell carcinoma
    • Kristensen GB, Holm R, Abele V, et al. Evaluation of the prognostic significance of cathepsin D, epidermal growth factor receptor, and c-erbB-2 in early cervical squamous cell carcinoma. An immunohistochemical study. Cancer 1996; 78:433-40.
    • (1996) An Immunohistochemical Study. Cancer , vol.78 , pp. 433-440
    • Kristensen, G.B.1    Holm, R.2    Abele, V.3
  • 52
    • 0031779550 scopus 로고    scopus 로고
    • Epidermal growth factor receptor expression in cervical intraepithelial neoplasia and its modulation during an a-difluoromethylornithine chemopreven-tion trial
    • Boiko IV, Mitchell MF, Hu W, et al. Epidermal growth factor receptor expression in cervical intraepithelial neoplasia and its modulation during an a-difluoromethylornithine chemopreven-tion trial. Clin Cancer Res 1998;4:1383-91.
    • (1998) Clin Cancer Res , vol.4 , pp. 1383-1391
    • Boiko, I.V.1    Mitchell, M.F.2    Hu, W.3
  • 53
    • 0025073536 scopus 로고
    • Expression of epidermal growth factor receptor and Her-2/Neu in normal and neoplastic cervix, vulva, and vagina
    • Berchuck A, Rodrigues G, Kamel A, et al. Expression of epidermal growth factor receptor and Her-2/Neu in normal and neoplastic cervix, vulva, and vagina. Obstet Gynecol 1990; 76:381-7.
    • (1990) Obstet Gynecol , vol.76 , pp. 381-387
    • Berchuck, A.1    Rodrigues, G.2    Kamel, A.3
  • 54
    • 33244463813 scopus 로고    scopus 로고
    • Complex networks orchestrate epithelial-mesenchymal transitions
    • Thiery JP, Sleeman JP. Complex networks orchestrate epithelial- mesenchymal transitions. Nat Mol Cell Biol 2006;7: 131-42.
    • (2006) Nat Mol Cell Biol , vol.7 , pp. 131-142
    • Thiery, J.P.1    Sleeman, J.P.2
  • 55
    • 50249141697 scopus 로고    scopus 로고
    • Molecular and pathological signatures of epithelial-mesenchymal transition at cancer invasion front
    • Wever O, Pauwels P, Craene B, et al. Molecular and pathological signatures of epithelial-mesenchymal transition at cancer invasion front. Histochem Cell Biol 2008;130:481-94.
    • (2008) Histochem Cell Biol , vol.130 , pp. 481-494
    • Wever, O.1    Pauwels, P.2    Craene, B.3
  • 56
    • 63049123066 scopus 로고    scopus 로고
    • Transitions between epithelial and mesenchymal states: Acquisition of malignant and stem cell traits
    • Polyak K, Weinberg RA. Transitions between epithelial and mesenchymal states: acquisition of malignant and stem cell traits. Nat Rev Cancer 2009;9:265-73.
    • (2009) Nat Rev Cancer , vol.9 , pp. 265-273
    • Polyak, K.1    Weinberg, R.A.2
  • 58
    • 24344462237 scopus 로고    scopus 로고
    • Combined targeting of the epidermal growth factor receptor and cyclo-oxygenase-2 pathways
    • Lippman SM, Gibson N, Subbaramaiah K, et al. Combined targeting of the epidermal growth factor receptor and cyclo-oxygenase-2 pathways. Clin Cancer Res 2005;11:6097-9.
    • (2005) Clin Cancer Res , vol.11 , pp. 6097-6099
    • Lippman, S.M.1    Gibson, N.2    Subbaramaiah, K.3
  • 59
    • 40049084003 scopus 로고    scopus 로고
    • Inflammation, epithelial to mesenchymal transition, and epidermal growth factor receptor tyrosine kinase inhibitor resistance
    • Krysan K, Lee JM, Dohadwala M, et al. Inflammation, epithelial to mesenchymal transition, and epidermal growth factor receptor tyrosine kinase inhibitor resistance. J Thorac Oncol 2008;3:107-10.
    • (2008) J Thorac Oncol , vol.3 , pp. 107-110
    • Krysan, K.1    Lee, J.M.2    Dohadwala, M.3
  • 60
    • 74549155020 scopus 로고    scopus 로고
    • Cyclooxygenase-2 expression is related to the epithelial-to-mesenchymal transition on human colon cancers
    • Jang TJ, Jeon KH, Jung KH. Cyclooxygenase-2 expression is related to the epithelial-to-mesenchymal transition on human colon cancers. Yonsei Med J 2009;50:818-24.
    • (2009) Yonsei Med J , vol.50 , pp. 818-824
    • Jang, T.J.1    Jeon, K.H.2    Jung, K.H.3
  • 61
    • 70349307488 scopus 로고    scopus 로고
    • HER2/neu (c-erbB-2) gene amplification and protein expression are rare in uterine cervical neoplasia: A tissue microarray study of 814 archival specimens
    • Lesnikova I, Lidang M, Hamilton-Dutoit S, et al. HER2/neu (c-erbB-2) gene amplification and protein expression are rare in uterine cervical neoplasia: a tissue microarray study of 814 archival specimens. APMIS 2009;117:737-45.
    • (2009) APMIS , vol.117 , pp. 737-745
    • Lesnikova, I.1    Lidang, M.2    Hamilton-Dutoit, S.3
  • 62
    • 0028369855 scopus 로고
    • C-erbB-2 Oncoprotein expression is associated with poor prognosis in squamous cell carcinoma of the cervix
    • Oka K, Nakano T, Arai T. c-erbB-2 Oncoprotein expression is associated with poor prognosis in squamous cell carcinoma of the cervix. Cancer 1994;73:664-71.
    • (1994) Cancer , vol.73 , pp. 664-671
    • Oka, K.1    Nakano, T.2    Arai, T.3
  • 63
    • 0035077048 scopus 로고    scopus 로고
    • Abnormal expression of epidermal growth factor receptor an erbB-2 in squamous cell carcinoma of the cervix: Correlation with human papillomavi-rus and prognosis
    • Ngan HY, Cheung AN, Liu SS, et al. Abnormal expression of epidermal growth factor receptor an erbB-2 in squamous cell carcinoma of the cervix: correlation with human papillomavi-rus and prognosis. Tumour Biol 2001;22:176-83.
    • (2001) Tumour Biol , vol.22 , pp. 176-183
    • Ngan, H.Y.1    Cheung, A.N.2    Liu, S.S.3
  • 64
    • 0141869054 scopus 로고    scopus 로고
    • Selection of HER-2/neu-positive tumor cell in early stage cervical cancer: Implications for Herceptin-mediated therapy
    • Bellone S, Palmieri M, Gokden M, et al. Selection of HER-2/neu-positive tumor cell in early stage cervical cancer: implications for Herceptin-mediated therapy. Gynecol Oncol 2003;91:231-40.
    • (2003) Gynecol Oncol , vol.91 , pp. 231-240
    • Bellone, S.1    Palmieri, M.2    Gokden, M.3
  • 65
    • 34848863620 scopus 로고    scopus 로고
    • Value of staining intensity in the interpretation of immunohistochemistry for tumor markers in colorectal cancer
    • Zlobec I, Terracciano L, Jass JR, et al. Value of staining intensity in the interpretation of immunohistochemistry for tumor markers in colorectal cancer. Virchows Arch 2007;451: 763-9.
    • (2007) Virchows Arch , vol.451 , pp. 763-769
    • Zlobec, I.1    Terracciano, L.2    Jass, J.R.3
  • 66
    • 33745950635 scopus 로고    scopus 로고
    • Immunohistochemical and quantitative analysis of protein expression
    • Cregger M, Berger AJ, Rimm DL. Immunohistochemical and quantitative analysis of protein expression. Arch Pathol Lab Med 2006;130:1026-30.
    • (2006) Arch Pathol Lab Med , vol.130 , pp. 1026-1030
    • Cregger, M.1    Berger, A.J.2    Rimm, D.L.3


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