High prevalence of human metapneumovirus subtype B in cases presenting as severe acute respiratory illness: An experience at tertiary care hospital

Clinical Respiratory Journal

Volumn 8, Issue 2, 2014, Pages 225-233

  Jain, Bhawana ^a   Singh, Ajay Kr ^a   Dangi, Tanushree ^a   Agarwal, Anjali ^a   Verma, Anil Kumar ^a   Dwivedi, Mukesh ^a   Singh, Kaleshwar P ^a   Jain, Amita ^a  

^a KING GEORGE'S MEDICAL UNIVERSITY   (India)

Author keywords

Epidemiology; Human metapneumovirus; Nasopharyngeal aspirate; Respiratory syncytial virus; Severe acute respiratory illness

Indexed keywords

ADENOVIRUS; ADULT; ARTICLE; BOCAVIRUS; BRONCHIOLITIS; CHILD; CHRONIC OBSTRUCTIVE LUNG DISEASE; CONTROLLED STUDY; COUGHING; HOSPITAL ADMISSION; HUMAN; HUMAN METAPNEUMOVIRUS; HUMAN METAPNEUMOVIRUS INFECTION; HUMAN METAPNEUMOVIRUS SUBTYPE A; HUMAN METAPNEUMOVIRUS SUBTYPE B; INFANT; INFECTION RISK; INFLUENZA VIRUS A; INFLUENZA VIRUS B; MAJOR CLINICAL STUDY; MEASLES VIRUS; MEDICAL HISTORY; NASOPHARYNGEAL ASPIRATION; NUCLEOTIDE SEQUENCE; PARAINFLUENZA VIRUS 1; PARAINFLUENZA VIRUS 2; PARAINFLUENZA VIRUS 3; PARAINFLUENZA VIRUS 4; PREVALENCE; PRIORITY JOURNAL; REAL TIME POLYMERASE CHAIN REACTION; RESPIRATORY SYNCYTIAL PNEUMOVIRUS; RESPIRATORY SYNCYTIAL VIRUS INFECTION; SEASONAL VARIATION; SEIZURE; SEVERE ACUTE RESPIRATORY SYNDROME; TERTIARY CARE CENTER; WINTER; ADOLESCENT; EPIDEMIOLOGY; FEMALE; FOLLOW UP; GENETICS; INDIA; MALE; METAPNEUMOVIRUS; MIDDLE AGED; PARAMYXOVIRIDAE INFECTIONS; PRESCHOOL CHILD; RESPIRATORY TRACT INFECTIONS; RETROSPECTIVE STUDY; SEVERITY OF ILLNESS INDEX; STATISTICS AND NUMERICAL DATA; VIROLOGY; YOUNG ADULT;

VIRUS RNA;

ADOLESCENT; ADULT; CHILD; CHILD, PRESCHOOL; FEMALE; FOLLOW-UP STUDIES; HUMANS; INDIA; INFANT; MALE; METAPNEUMOVIRUS; MIDDLE AGED; PARAMYXOVIRIDAE INFECTIONS; PREVALENCE; REAL-TIME POLYMERASE CHAIN REACTION; RESPIRATORY TRACT INFECTIONS; RETROSPECTIVE STUDIES; RNA, VIRAL; SEVERITY OF ILLNESS INDEX; TERTIARY CARE CENTERS; YOUNG ADULT;

EID: 84898597597     PISSN: 17526981     EISSN: 1752699X     Source Type: Journal    
DOI: 10.1111/crj.12064     Document Type: Article

References (49)

1. Alto WA. Human metapneumovirus: a newly described respiratory tract pathogen. J Am Board Fam Pract. 2004;17: 466-469.
2. Kahn JS. Epidemiology of human metapneumovirus. Clin Microbiol Rev. 2006;19: 546-557.
3. Van den Hoogen BG, De Jong JC, Groen J, Kuiken T, de Groot R, Fouchier RA, Osterhaus AD. A newly discovered human pneumovirus isolated from young children with respiratory tract disease. Nat Med. 2001;7: 719-724.
4. Lamb RA, Collins PL, Kolakofsky D, Melero JA, Nagai Y, Oldstone MBA, Pringle CR, Rima BK. Family paramyxoviridae. In: Van Regenmortel MHV, Fauquet CM, Bishop DHL, etal., editors. Virus Taxonomy. San Diego, CA, Academic Press, 2000: 549-561.
5. Mufson MA, Orvell C, Rafnar B, Norrby E. Two distinct subtypes of human respiratory syncytial virus. J Gen Virol. 1985;66(10): 2111-2124.
6. Agrawal AS, Roy T, Ghosh S, Chawla-Sarkar M. Genetic variability of attachment (G) and Fusion (F) protein genes of human metapneumovirus strains circulating during 2006-2009 in Kolkata, Eastern India. Virol J. 2011;8: 67. doi: 10.1186/1743-422X-8-67.
7. Anderson LJ, Hierholzer JC, Tsou C, Hendry RM, Fernie BF, Stone Y, McIntosh K. Antigenic characterization of respiratory syncytial virus strains with monoclonal antibodies. J Infect Dis. 1985;151: 626-633.
8. Agapov E, Sumino KC, Keener MG, Storch GA, Holtzman MJ. Genetic variability of human metapneumovirus infection: evidence of a shift in viral genotype without a change in illness. J Infect Dis. 2006;193: 396-403.
9. Williams JV, Edwards KM, Weinberg GA, etal. Population-based incidence of human metapneumovirus infection among hospitalized children. J Infect Dis. 2010;201(12): 1890-1898.
10. Spaeder MC, Custer JW, Bembea MM, Aganga DO, Song X, Scafidi S. A multicenter outcomes analysis of children with severe viral respiratory infection due to human metapneumovirus. Pediatr Crit Care Med. 2013;14: 268-272.
11. Banerjee S, Sullender WM, Choudekar A, John C, Tyagi V, Fowler K, Lefkowitz EJ, Broor S. Detection and genetic diversity of human metapneumovirus in hospitalized children with acute respiratory infections in India. J Med Virol. 2011;83(10): 1799-1810. doi: 10.1002/jmv.22176.
12. Williams JV, Harris PA, Tollefson SJ, Halburnt-Rush LL, Pingster-haus JM, Edwards KM, Wright PF, Crowe JE Jr. Human metapneumovirus and lower respiratory tract disease in otherwise healthy infants and children. N Engl J Med. 2004;350: 443-450.
13. Boivin G, Abed Y, Pelletier G, Ruel L, Moisan D, Côté S, Peret TC, Erdman DD, Anderson LJ. Virological features and clinical manifestations associated with human metapneumovirus: a new paramyxovirus responsible for acute respiratory-tract infections in all age groups. J Infect Dis. 2002;186: 1330-1334.
14. van den Hoogen BG, Herfst S, Sprong L, Aganga DO, Song X, Scafidi S. Antigenic and genetic variability of human metapneumoviruses. Emerg Infect Dis. 2004;10: 658-666.
15. Falsey AR, Erdman D, Anderson LJ, Walsh EE. Human metapneumovirus infections in young and elderly adults. J Infect Dis. 2003;187: 785-790.
16. Peiris JS, Tang WH, Chan KH, Khong PL, Guan Y, Lau YL, Chiu SS. Children with respiratory disease associated with metapneumovirus in Hong Kong. Emerg Infect Dis. 2003;9: 628-633.
17. Van Den Hoogen BG, Van Doornum GJ, Fockens JC, Cornelissen JJ, Beyer WEP, de Groot R, Osterhaus ADME, Fouchier RAM. Prevalence and clinical symptoms of human metapneumovirus infection in hospitalized patients. J Infect Dis. 2003;188: 1571-1577.
18. Viazov S, Ratjen F, Scheidhauer R, Fiedler M, Roggendorf M. High prevalence of human metapneumovirus infection in young children and genetic heterogeneity of the viral isolates. J Clin Microbiol. 2003;41: 3043-3045.
19. Vicente D, Montes M, Cilla G, Perez-Yarza EG, Perez-Trallero E. Differences in clinical severity between genotype A and genotype B human metapneumovirus infection in children. Clin Infect Dis. 2006;42: e111-113.
20. Pitoiset C, Darniot M, Huet F, Aho SL, Pothier P, Manoha C. Human metapnuemovirus genotypes and severity of disease in young children (n=100) during a 7-year study in Dijon Hospital, France. J Med Virol. 2010;82: 1782-1789.
21. WHO guidance for the surveillance of human infection with new influenza A (H1N1) virus posted on WHO website on 29 April 2009. Based on Global surveillance during an influenza pandemic. Updated December 30, 2011. Available at: http://www.who.int/csr/resources/publications/swineflu/surveillance/en/index.html (accessed 15 May 2013).
22. World Health Organization. Human infection with pandemic (H1N1) 2009 virus: updated interim WHO guidance on global surveillance. Available at: http://www.who.int/csr/disease/swineflu/WHO_case_definition_swine_flu_2009_04_29.pdf (accessed 15 May 2013).
23. World Health Organization. Technical Bases for the WHO Recommendations on the Management of Pneumonia in Children at Firstlevel Health Facilities. Geneva, World Health Organization, 1991.
24. World Health Organization. Programme for the Control of Acute Respiratory Infections. Acute Respiratory Infections in Children: Case Management in Small Hospitals in Developing Countries. A Manual for Doctors and Other Senior Health Workers. Geneva, World Health Organization, 1990.
25. Lakhanpaul M, Armon K, Eccleston P, MacFaul R, Smith S, Vyas H, Werneke U, Williams L, Stephenson T. An Evidence Based Guideline for the Management of Children Presenting with Acute Breathing Difficulty. Nottingham, University of Nottingham, 2002. Available at: http://www.nottingham.ac.uk/paediatric-guideline/breathingguideline.pdf (accessed 22 August 2006).
26. Albert RH. Diagnosis and treatment of acute bronchitis. Am Fam Physician. 2010;82(11): 1345-1350.
27. Isenberg HD. Clinical microbiology procedures handbook. Specimen collection and processing. 2nd edn updates. 2007; Pg 10.4.4.
28. Potdar VA, Chadha MS, Jadhav SM, Mullick J, Cherian SS, Mishra AC. Genetic characterization of the influenza A pandemic (H1N1) 2009 virus isolates from India. PLoS ONE. 2010;5: e9693.
29. Hubschen MJ, Kremer JR, Landtsheer SD, Muller CP. A multiplex TaqMan PCR assay for the detection of measles and rubella virus. J Virol Methods. 2008;149: 246-250.
30. Jothikumar N, Cromeans TL, Hill VR, Lu X, Sobsey MD, Erdman DD. Quantitative real-time PCR assays for detection of human adenoviruses and identification of serotypes 40 and 41. Appl Environ Microbiol. 2005;71: 3131-3136.
31. Lu X, Chittaganpitch M, Olsen SJ, Mackay IM, Sloots TP, Fry AM, Erdman DD. Real-time PCR assays for detection of bocavirus in human specimens. J Clin Microbiol. 2006;44: 3231-3235.
32. Templeton KE, Scheltinga SA, Beersma MF, Kroes AC, Claas EC. Rapid and sensitive method using multiplex real-time PCR for diagnosis of infections by influenza A and influenza B viruses, respiratory syncytial virus, and parainfluenza viruses 1, 2, 3, and 4. J Clin Microbiol. 2004;42: 1564-1569.
33. Peret TC, Hall CB, Schnabel KC, Golub JA, Anderson LJ. Circulation patterns of genetically distinct group A and B strains of human respiratory syncytial virus in a community. J Gen Virol. 1998;79: 2221-2229.
34. Peret TCT, Hall CB, Hammond GW, Piedra PA, Storch GA, Sullender WM, Tsou C, Anderson LJ. Circulation patterns of group A and B human respiratory syncytial virus genotypes in 5 com-munities in North America. J Infect Dis. 2000;181: 1891-1896.
35. Zlateva KT, Lemey P, Moes E, Vandamme AM, Van Ranst M. Genetic variability and molecular evolution of the human respiratory syncytial virus subgroup B attachment G protein. J Virol. 2005;79(14): 9157-9167.
36. Ludewick HP, Abed Y, van Niekerk N, Boivin G, Klugman KP, Madhi SA. Human metapneumovirus genetic variability, South Africa. Emerg Infect Dis. 2005;11(7): 1074-1078.
37. Tillmann RL, Simon A, Müller A, Schildgen O. Sensitive commercial NASBA assay for the detection of respiratory syncytial virus in clinical specimen. PLoS ONE. 2007;2(12): e1357. doi:10.1371/journal.pone.0001357.
38. Kumar S, Tamura K, Nei M. MEGA3: Integrated software for Molecular Evolutionary Genetics Analysis and sequence alignment. Brief Bioinform. 2004;5: 150-163.
39. Rafiefard F, Yun Z, Orvell C. Epidemiologic characteristics and seasonal distribution of human metapneumovirus infections in five epidemic seasons in stockholm, sweden, 2002-2006. J Med Virol. 2008;80: 1631-1638.
40. Banerjee S, Bharaj P, Sullender W, Kabra SK, Broor S. Human metapneumovirus infections among children with acute respiratory infections seen in a large referral hospital in India. J Clin Virol. 2007;38(1): 70-72.
41. Broor S, Parveen S, Bharaj P, Prasad VS, Srinivasulu KN, Sumanth KM, Kapoor SK, Fowler K, Sullender WM. A prospective three-year cohort study of the epidemiology and virology of acute respiratory infections of children in rural India. PLoS ONE. 2007;2: e491.
42. Agrawal AS, Sarkar M, Chakrabarti S, Rajendran K, Kaur H, Mishra AC, Chatterjee MK, Naik TN, Chadha MS, Chawla-Sarkar M. Comparative evaluation of real-time PCR and conventional RT-PCR during a 2 year surveillance for influenza and respiratory syncytial virus among children with acute respiratory infections in Kolkata, India, reveals a distinct seasonality of infection. J Med Microbiol. 2009;58: 1616-1622.
43. Kim YK, Kim JW, Wee YS, Yoo EG, Han MY. Clinical features of human metapneumovirus and respiratory syncytial virus infection in hospitalized children. Pediatr Allergy Respir Dis. 2009;19: 12-19.
44. Kim CK, Choi J, Callaway Z, Kim HB, Chung JY, Koh YY, Shin BM. Clinical and epidemiological comparison of human metapneumovirus and respiratory syncytial virus in Seoul, Korea, 2003-2008. J Korean Med Sci. 2010;25: 342-347.
45. Hamelin ME, Cote S, Laforge J, Lampron N, Bourbeau J, Weiss K, Gilca R, DeSerres G, Boivin G. Human metapneumovirus infection in adults with community-acquired pneumonia and exacerbation of chronic obstructive pulmonary disease. Clin Infect Dis. 2005;41: 498-502.
46. Williams JV, Crowe JE Jr, Enriquez R, Minton P, Peebles RS Jr, Hamilton RG, Higgins S, Griffin M, Hartert TV. Human metapneumovirus infection plays an etiologic role in acute asthma exacerbations requiring hospitalization in adults. J Infect Dis. 2005;192: 1149-1153.
47. Jokela P, Piiparinen H, Luiro K, Lappalainen M. Detection of human metapneumovirus and respiratory syncytial virus by duplex real-time RT-PCR assay in comparison with direct fluorescent assay. Clin Microbiol Infect. 2010;16: 1568-1573.
48. Hu A, Colella M, Tam JS, Rappaport R, Cheng SM. Simultaneous detection, subgrouping, and quantitation of respiratory syncytial virus A and B by real-time PCR. J Clin Microbiol. 2003;41: 149-154.
49. Okayama Y. Cellular and humoral immunity of virus-induced asthma. Front Microbiol. 2013;4: 252.