The changes of neutrophil gelatinase-associated lipocalin in plasma and its expression in adipose tissue in pregnant women with gestational diabetes

Diabetes Research and Clinical Practice

Volumn 104, Issue 1, 2014, Pages 136-142

  Lou, Yanqin ^a   Wu, Chaoying ^a   Wu, Min ^a   Xie, Cui ^b   Ren, Lirong ^b  

^a HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

^b Birth Defects Prevention Research and Transformation Team   (China)

Author keywords

Adipose tissue; Gene expression; Gestational diabetes mellitus; Neutrophil gelatinase associated lipocalin; Tumor necrosis factor

Indexed keywords

C REACTIVE PROTEIN; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; INSULIN; LOW DENSITY LIPOPROTEIN CHOLESTEROL; MESSENGER RNA; NEUTROPHIL GELATINASE ASSOCIATED LIPOCALIN; TRIACYLGLYCEROL; TUMOR NECROSIS FACTOR ALPHA; ACUTE PHASE PROTEIN; LCN2 PROTEIN, HUMAN; LIPOCALIN; ONCOPROTEIN; RNA;

ADULT; ARTICLE; BIRTH WEIGHT; BODY MASS; CHINESE; CHOLESTEROL BLOOD LEVEL; COMPARATIVE STUDY; CONTROLLED STUDY; DISEASE ASSOCIATION; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; GLUCOSE BLOOD LEVEL; GLUCOSE HOMEOSTASIS; HUMAN; HUMAN TISSUE; INSULIN BLOOD LEVEL; INSULIN RESISTANCE; MAJOR CLINICAL STUDY; NEUTROPHIL; OBESITY; PREGNANCY DIABETES MELLITUS; PROTEIN BLOOD LEVEL; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; SUBCUTANEOUS FAT; TRIACYLGLYCEROL BLOOD LEVEL; WESTERN BLOTTING; ADIPOSE TISSUE; BLOOD; FOLLOW UP; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; PREGNANCY; RETROSPECTIVE STUDY;

ACUTE-PHASE PROTEINS; ADIPOSE TISSUE; ADULT; BLOTTING, WESTERN; BODY MASS INDEX; DIABETES, GESTATIONAL; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; FOLLOW-UP STUDIES; GENE EXPRESSION REGULATION; HUMANS; INSULIN RESISTANCE; LIPOCALINS; OBESITY; PREGNANCY; PROTO-ONCOGENE PROTEINS; REAL-TIME POLYMERASE CHAIN REACTION; RETROSPECTIVE STUDIES; RNA;

EID: 84898549356     PISSN: 01688227     EISSN: 18728227     Source Type: Journal    
DOI: 10.1016/j.diabres.2014.01.014     Document Type: Article

References (28)

1. Kershaw E.E., Flier J.S. Adipose tissue as an endocrine organ. J Clin Endocrinol Metab 2004, 89:2548-2556.
2. Badman M.K., Flier J.S. The adipocyte as an active participant in energy balance and metabolism. Gastroenterology 2007, 132:2103-2115.
3. Fruhbeck G., Gomez-Ambrosi J. Rationale for the existence of additional adipostatic hormones. FASEB J 2001, 15:1996-2006.
4. Fruhbeck G., Gomez-Ambrosi J. Control of body weight: a physiologic and transgenic perspective. Diabetologia 2003, 46:143-172.
5. Trayhurn P. Adipocyte biology. Obes Rev 2007, 8(Suppl 1):41-44.
6. Fernandez-Real J.M., Ricart W. Insulin resistance and chronic cardiovascular inflammatory syndrome. Endocr Rev 2003, 24:278-301.
7. Kjeldsen L., Bainton D.F., Sengelov H., Borregaard N. Identification of neutrophil gelatinase-associated lipocalin as a novel matrix protein of specific granules in human neutrophils. Blood 1994, 83:799-807.
8. Wang Y., Lam K.S., Kraegen E.W., Sweeney G., Zhang J., Tso A.W., et al. Lipocalin-2 is an inflammatory marker closely associated with obesity, insulin resistance, and hyperglycemia in humans. Clin Chem 2007, 53:34-41.
9. Kirwan J.P., Hauguel-De M.S., Lepercq J., Challier J.C., Huston-Presley L., Friedman J.E., et al. TNF-alpha is a predictor of insulin resistance in human pregnancy. Diabetes 2002, 51:2207-2213.
10. American Diabetes A. Diagnosis and classification of diabetes mellitus. Diabetes Care 2011, 34:S62-S69.
11. Moreno-Navarrete J.M., Manco M., Ibanez J., Garcia-Fuentes E., Ortega F., Gorostiaga E., et al. Metabolic endotoxemia and saturated fat contribute to circulating NGAL concentrations in subjects with insulin resistance. Int J Obes (Lond) 2010, 34:240-249.
12. Cemgil A.D., Ozkaya M., Adali E., Kilinc M., Coskun A., Ozer A., et al. Plasma lipocalin-2 levels in pregnant women with pre-eclampsia, and their relation with severity of disease. J Matern Fetal Neonatal Med 2011, 24:291-296.
13. Cakal E., Ozkaya M., Engin-Ustun Y., Ustun Y. Serum lipocalin-2 as an insulin resistance marker in patients with polycystic ovary syndrome. J Endocrinol Invest 2011, 34:97-100.
14. Daniels L.B., Barrett-Connor E., Clopton P., Laughlin G.A., Ix J.H., Maisel A.S. Plasma neutrophil gelatinase-associated lipocalin is independently associated with cardiovascular disease and mortality in community-dwelling older adults: The Rancho Bernardo Study. J Am Coll Cardiol 2012, 59:1101-1109.
15. Yan Q.W., Yang Q., Mody N., Graham T.E., Hsu C.H., Xu Z., et al. The adipokine lipocalin 2 is regulated by obesity and promotes insulin resistance. Diabetes 2007, 56:2533-2540.
16. Edelstam G., Lowbeer C., Kral G., Gustafsson S.A., Venge P. New reference values for routine blood samples and human neutrophilic lipocalin during third-trimester pregnancy. Scand J Clin Lab Invest 2001, 61:583-592.
17. D'Anna R., Baviera G., Corrado F., Giordano D., Recupero S., Di Benedetto A. First trimester serum neutrophil gelatinase-associated lipocalin in gestational diabetes. Diabet Med 2009, 26:1293-1295.
18. Tataranni P.A., Ortega E. A burning question: does an adipokine-induced activation of the immune system mediate the effect of overnutrition on type 2 diabetes?. Diabetes 2005, 54:917-927.
19. Xu H., Barnes G.T., Yang Q., Tan G., Yang D., Chou C.J., et al. Chronic inflammation in fat plays a crucial role in the development of obesity-related insulin resistance. J Clin Invest 2003, 112:1821-1830.
20. Skurk T., Alberti-Huber C., Herder C., Hauner H. Relationship between adipocyte size and adipokine expression and secretion. J Clin Endocrinol Metab 2007, 92:1023-1033.
21. Salmi A.A., Zaki N.M., Zakaria R., Nor A.A., Rasool A.H. Arterial stiffness, inflammatory and pro-atherogenic markers in gestational diabetes mellitus. Vasa 2012, 41:96-104.
22. Coughlan M.T., Oliva K., Georgiou H.M., Permezel J.M., Rice G.E. Glucose-induced release of tumour necrosis factor-alpha from human placental and adipose tissues in gestational diabetes mellitus. Diabet Med 2001, 18:921-927.
23. Catalan V., Gomez-Ambrosi J., Rodriguez A., Ramirez B., Silva C., Rotellar F., et al. Increased adipose tissue expression of lipocalin-2 in obesity is related to inflammation and matrix metalloproteinase-2 and metalloproteinase-9 activities in humans. J Mol Med (Berl) 2009, 87:803-813.
24. Auguet T., Quintero Y., Terra X., Martinez S., Lucas A., Pellitero S., et al. Upregulation of lipocalin 2 in adipose tissues of severely obese women: positive relationship with proinflammatory cytokines. Obesity (Silver Spring) 2011, 19:2295-2300.
25. Zhang J., Wu Y., Zhang Y., Leroith D., Bernlohr D.A., Chen X. The role of lipocalin 2 in the regulation of inflammation in adipocytes and macrophages. Mol Endocrinol 2008, 22:1416-1426.
26. Ivy K.M., Law A.X. Lipocalin-2 deficiency attenuates insulin resistance Associated with aging and obesity. Diabetes 2010.
27. Tan B.K., Adya R., Shan X., Syed F., Lewandowski K.C., O'Hare J.P., et al. Ex vivo and in vivo regulation of lipocalin-2, a novel adipokine, by insulin. Diabetes Care 2009, 32:129-131.
28. Guo H., Jin D., Zhang Y., Wright W., Bazuine M., Brockman D.A., et al. Lipocalin-2 deficiency impairs thermogenesis and potentiates diet-induced insulin resistance in mice. Diabetes 2010, 59:1376-1385.