Comparative proteomic analysis of malignant pleural mesothelioma evidences an altered expression of nuclear lamin and filament-related proteins

Proteomics - Clinical Applications

Volumn 8, Issue 3-4, 2014, Pages 258-268

  Giusti, Laura ^a   Da Valle, Ylenia ^a   Bonotti, Alessandra ^b   Donadio, Elena ^a   Ciregia, Federica ^a   Ventroni, Tiziana ^a   Foddis, Rudy ^a   Giannaccini, Gino ^a   Guglielmi, Giovanni ^b   Cristaudo, Alfonso ^b   Lucacchini, Antonio ^a  

^a UNIVERSITY OF PISA   (Italy)

^b UNIVERSITY HOSPITAL OF PISA   (Italy)

Author keywords

Biomarkers; Lung; Mesothelioma; Prelamin A C

Indexed keywords

BIOLOGICAL MARKER; CALRETININ; DESMIN; FRUCTOSE BISPHOSPHATE ALDOLASE; ISOPROTEIN; LAMIN; MYOSIN LIGHT CHAIN; MYOSIN LIGHT CHAIN 3; MYOSIN LIGHT CHAIN 6B; MYOSIN REGULATORY LIGHT CHAIN 2; PRELAMIN A; PRELAMIN C; TUMOR MARKER; UNCLASSIFIED DRUG; VIMENTIN; ASBESTOS; LAMIN B; LAMIN B2; TUMOR PROTEIN;

ADULT; AGED; ARTICLE; BENIGN TUMOR; COMPARATIVE STUDY; COMPUTER PROGRAM; CONTROLLED STUDY; DIFFERENTIAL DIAGNOSIS; FEMALE; HUMAN; HUMAN TISSUE; LUNG CARCINOMA; MAJOR CLINICAL STUDY; MALE; MASS SPECTROMETRY; NUCLEOTIDE SEQUENCE; PLEURA MESOTHELIOMA; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEOMICS; SIGNAL TRANSDUCTION; THORACOSCOPY; TUMOR BIOPSY; TWO DIMENSIONAL GEL ELECTROPHORESIS; VALIDATION PROCESS; WESTERN BLOTTING; BIOSYNTHESIS; CHEMICALLY INDUCED; GENE EXPRESSION REGULATION; GENE REGULATORY NETWORK; GENETICS; LUNG TUMOR; MESOTHELIOMA; MIDDLE AGED; PATHOLOGY; PLEURA TUMOR; VERY ELDERLY;

ADULT; AGED; AGED, 80 AND OVER; ASBESTOS; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; GENE REGULATORY NETWORKS; HUMANS; LAMIN TYPE B; LUNG NEOPLASMS; MALE; MESOTHELIOMA; MIDDLE AGED; NEOPLASM PROTEINS; PLEURAL NEOPLASMS; PROTEOMICS; TUMOR MARKERS, BIOLOGICAL;

EID: 84898548580     PISSN: 18628346     EISSN: 18628354     Source Type: Journal    
DOI: 10.1002/prca.201300052     Document Type: Article

References (36)

1. Robinson, B. W., Lake, R. A., Advances in malignant mesothelioma. N. Engl. J. Med. 2005, 353, 1591-1603.
2. Cristaudo, A., Foddis, R., Vivaldi, A., Buselli, R. et al., SV40 enhances the risk of malignant mesothelioma among people exposed to asbestos: a molecular epidemiologic case-control study. Cancer Res. 2005, 65, 3049-3052.
3. Melaiu, O., Cristaudo, A., Melissari, E., Di Russo, M. et al., A review of transcriptome studies combined with data mining reveals novel potential markers of malignant pleural mesothelioma. Mutat. Res. 2012, 750, 132-140.
4. Cristaudo, A., Foddis, R., Vivaldi, A., Guglielmi, G. et al., Clinical significance of serum mesothelin in patients with mesothelioma and lung cancer. Clin. Cancer Res. 2007, 13, 5076-5081.
5. Robinson, B. W., Musk, A. W., Lake, R. A., Malignant mesothelioma. Lancet 2005, 366, 397-408.
6. Cristaudo, A., Bonotti, A., Simonini, S., Vivaldi, A. et al., Combined serum mesothelin and plasma osteopontin measurements in malignant pleural mesothelioma. J. Thorac. Oncol. 2011, 6, 1587-1593.
7. Hegmans, J. P., Veltman, J. D., Fung, E. T., Verch, T. et al., Protein profiling of pleural effusions to identify malignant pleural mesothelioma using SELDI-TOF MS. Technol. Cancer Res. Treat. 2009, 8, 323-332.
8. Hegmans, J. P., Bard, M. P., Hemmes, A., Luider, T. M. et al., Proteomic analysis of exosomes secreted by human mesothelioma cells. Am. J. Pathol. 2004, 164, 1807-1815.
9. Kuramitsu, Y., Miyamoto, H., Tanaka, T., Zhang, X. et al., Proteomic differential display analysis identified upregulated astrocytic phosphoprotein PEA-15 in human malignant pleural mesothelioma cell lines. Proteomics 2009, 9, 5078-5089.
10. Hosako, M., Muto, T., Nakamura, Y., Tsuta, K. et al., Proteomic study of malignant pleural mesothelioma by laser microdissection and two-dimensional difference gel electrophoresis identified cathepsin D as a novel candidate for a differential diagnosis biomarker. J. Proteomics 2012, 75, 833-844.
11. Giusti, L., Baldini, C., Bazzichi, L., Ciregia, F. et al., Proteome analysis of whole saliva: a new tool for rheumatic diseases-the example of Sjögren's syndrome. Proteomics 2007, 7, 1634-1643.
12. Giusti, L., Iacconi, P., Da Valle, Y., Ciregia, F. et al., A proteomic profile of washing fluid from the colorectal tract to search for potential biomarkers of colon cancer. Mol. Biosyst. 2012, 8, 1088-1099.
13. Aude-Garcia, C., Collin-Faure, V., Luche, S., Rabilloud, T., Improvements and simplifications in in-gel fluorescent detection of proteins using ruthenium II tris-(bathophenanthroline disulfonate): the poor man's fluorescent detection method. Proteomics 2011, 11, 324-328.
14. Scherl, A., Tsai, Y. S., Shaffer, S. A., Goodlett, D. R., Increasing information from shotgun proteomic data by accounting for misassigned precursor ion masses. Proteomics 2008, 8, 2791-2797.
15. Rascoe, P. A., Jupiter, D., Cao, X., Littlejohn, J. E., Smythe, W. R., Molecular pathogenesis of malignant mesothelioma. Expert Rev. Mol. Med. 2012, 14, e12.
16. Lee, A. Y., Raz, D. J., He, B., Jablons, D. M., Update on the molecular biology of malignant mesothelioma. Cancer 2007, 109, 1454-1461.
17. Cao, X., Littlejohn, J., Rodarte, C., Zhang, L. et al., Up-regulation of Bcl-xl by hepatocyte growth factor in human mesothelioma cells involves ETS transcription factors. Am. J. Pathol. 2009, 175, 2207-2216.
18. Ordóñez, N. G., Application of immunohistochemistry in the diagnosis of epithelioid mesothelioma: a review and update. Hum. Pathol. 2013, 44, 1-19.
19. Ziegler, A., Cerciello, F., Bigosch, C., Bausch-Fluck, D. et al., Proteomic surfaceome analysis of mesothelioma. Lung Cancer 2012, 75, 189-196.
20. Muchir, A., Worman, H. J., The nuclear envelope and human disease. Physiology (Bethesda) 2004, 19, 309-314.
21. Hutchison, C. J., Worman, H. J., A-type lamins: guardians of the soma? Nat. Cell Biol. 2004, 6, 1062-1067.
22. Young, S. G., Jung, H. J., Coffinier, C., Fong, L. G., Understanding the roles of nuclear A-and B-type lamins in brain development. J. Biol. Chem. 2012, 287, 16103-16110.
23. Liu, B., Zhou, Z., Lamin A/C, laminopathies and premature ageing. Histol. Histopathol. 2008, 23, 747-763.
24. Davies, B. S., Coffinier, C., Yang, S. H., Barnes, R. H., 2nd et al., Investigating the purpose of prelamin A processing. Nucleus 2011, 2, 4-9.
25. Edwards, J. G., Cox, G., Andi, A., Jones, J. L. et al., Angiogenesis is an independent prognostic factor in malignant mesothelioma. Br. J. Cancer 2001, 85, 863-868.
26. Ohta, Y., Shridhar, V., Bright, R. K., Kalemkerian, G. P. et al., VEGF and VEGF type C play an important role in angiogenesis and lymphangiogenesis in human malignant mesothelioma tumours. Brit. J. Cancer 1999, 8, 54-61.
27. Kumar-Singh, S., Weyler, J., Martin, K. J., Vermeulen, P. B., Van Marck, E., Angiogenic cytokines in mesothelioma: a study of VEGF, FGF-1 and -2, and TGF beta expression. J. Pathol. 1999, 189, 72-78.
28. Ceresoli, G. L., Zucali, P. A., Anti-angiogenic therapies for malignant pleural mesothelioma. Expert Opin. Investig. Drugs 2012, 21, 833-844.
29. Kelly, R. J., Sharon, E., Hassan, R., Chemotherapy and targeted therapies for unresectable malignant mesothelioma. Lung Cancer 2011, 73, 256-263.
30. Giusti, L., Cetani, F., Ciregia, F., Da Valle, Y. et al., A proteomic approach to study parathyroid glands. Mol. BioSyst. 2011, 7, 687-699.
31. Giusti, L., Iacconi, P., Ciregia, F., Giannaccini, G. et al., Fine-needle aspiration of thyroid nodules: proteomic analysis to identify cancer biomarkers. J. Proteome Res. 2008, 7, 4079-4088.
32. Musgrove, E. A., Caldon, C. E., Barraclough, J., Stone, A., Sutherland, R. L., Cyclin D as a therapeutic target in cancer. Nat. Rev. Cancer 2011, 11, 558-572.
33. Satelli, A., Li, S., Vimentin in cancer and its potential as a molecular target for cancer therapy. Cell. Mol. Life Sci. 2011, 68, 3033-3046.
34. Stewart, C. J., Crook, M. L., Little, L., Louwen, K., Correlation between invasive pattern and immunophenotypic alterations in endocervical adenocarcinoma. Histopathology 2011, 58, 720-728.
35. Chen, D., Zhang, Y., Zhang, X., Li, J. et al., Overexpression of integrin-linked kinase correlates with malignant phenotype in non-small cell lung cancer and promotes lung cancer cell invasion and migration via regulating epithelial-mesenchymal transition (EMT)-related genes. Acta Histochem. 2013, 115, 128-136.
36. Liu, W. F., Ji, S. R., Sun, J. J. et al., CD146 Expression correlates with epithelial-mesenchymal transition markers and a poor prognosis in gastric cancer. Int. J. Mol. Sci. 2012, 13, 6399-6406.