The regulation of 2,3-butanediol synthesis in Klebsiella pneumoniae as revealed by gene over-expressions and metabolic flux analysis

Bioprocess and Biosystems Engineering

Volumn 37, Issue 3, 2014, Pages 343-353

  Lu, Mingshou ^a   Park, Changhun ^a   Lee, Soojin ^a   Kim, Borim ^a   Oh, Min Kyu ^b   Um, Youngsoon ^c   Kim, Jungwook ^a   Lee, Jinwon ^a  

^a Sogang University   (South Korea)

^b Korea University   (South Korea)

^c Korea Institute of Science and Technology   (South Korea)

Author keywords

2,3 butanediol; Acetolactate decarboxylase; Acetolactate synthase; Butantediol dehydrogenase; Metabolic flux analysis

Indexed keywords

AMINO ACIDS; BACTERIA; CELL GROWTH; ENZYMES; GENE EXPRESSION; GROWTH KINETICS; METABOLISM; PHYSIOLOGY;

2 ,3-BUTANEDIOL; ACETOLACTATE SYNTHASE; BUTANTEDIOL DEHYDROGENASE; DECARBOXYLASES; METABOLIC FLUX ANALYSIS;

GENE EXPRESSION REGULATION;

2,3 BUTANEDIOL; ACETOIN; ACETOLACTATE DECARBOXYLASE; ACETOLACTATE SYNTHASE; BRANCHED CHAIN AMINO ACID; BUTANEDIOL DEHYDROGENASE; CARBON; CARBOXYLYASE; NICOTINAMIDE ADENINE DINUCLEOTIDE; OXIDOREDUCTASE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE; UNCLASSIFIED DRUG; 2,3-BUTYLENE GLYCOL; BUTANEDIOL;

ARTICLE; BACTERIAL CELL; BACTERIAL GENE; BACTERIAL STRAIN; BACTERIUM MUTANT; BIOSYNTHESIS; BUDA GENE; BUDB GENE; BUDC GENE; CARBON METABOLISM; CELL GROWTH; CONTINUOUS CULTURE; CONTROLLED STUDY; ENZYME ANALYSIS; ENZYME MECHANISM; GENE OVEREXPRESSION; KLEBSIELLA PNEUMONIAE; METABOLIC FLUX ANALYSIS; MOLECULAR INTERACTION; NONHUMAN; PRIORITY JOURNAL; REGULATORY MECHANISM; STEADY STATE; WILD TYPE; BIOMASS; GENE EXPRESSION; GENETICS; METABOLISM;

BIOMASS; BUTYLENE GLYCOLS; GENE EXPRESSION; GENES, BACTERIAL; KLEBSIELLA PNEUMONIAE;

EID: 84898542991     PISSN: 16157591     EISSN: 16157605     Source Type: Journal    
DOI: 10.1007/s00449-013-0999-y     Document Type: Article

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