Orthotopic models of pediatric brain tumors in zebrafish

Oncogene

Volumn 34, Issue 13, 2015, Pages 1736-1742

  Eden, C J ^a   Ju, B ^a   Murugesan, M ^a   Phoenix, T N ^a   Nimmervoll, B ^a   Tong, Y ^a   Ellison, D W ^a   Finkelstein, D ^a   Wright, K ^a   Boulos, N ^a   Dapper, J ^a   Thiruvenkatam, R ^a   Lessman, C A ^b   Taylor, M R ^a   Gilbertson, R J ^a  

^a ST JUDE CHILDREN S RESEARCH HOSPITAL   (United States)

^b University of Memphis   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

TRANSCRIPTOME;

ANIMAL; BRAIN TUMOR; CANCER TRANSPLANTATION; CHILD; DISEASE MODEL; DRUG DEVELOPMENT; GLIOMA; HIGH THROUGHPUT SCREENING; HUMAN; MOUSE; PATHOLOGY; XENOGRAFT; ZEBRA FISH;

ANIMALS; BRAIN NEOPLASMS; CHILD; DISEASE MODELS, ANIMAL; DRUG DISCOVERY; GLIOMA; HIGH-THROUGHPUT SCREENING ASSAYS; HUMANS; MICE; NEOPLASM TRANSPLANTATION; TRANSCRIPTOME; TRANSPLANTATION, HETEROLOGOUS; ZEBRAFISH;

EID: 84898520210     PISSN: 09509232     EISSN: 14765594     Source Type: Journal    
DOI: 10.1038/onc.2014.107     Document Type: Article

References (30)

1. Smith MA, Seibel NL, Altekruse SF, Ries LA, Melbert DL, O'Leary M, et al. Outcomes for children and adolescents with cancer: challenges for the twenty-first century. J Clin Oncol 2010; 28: 2625-2634.
2. Kawauchi D, Robinson G, Uziel T, Gibson P, Rehg J, Gao C, et al. A mouse model of the most aggressive subgroup of human medulloblastoma. Cancer Cell 2012; 21: 168-180.
3. Gibson P, Tong Y, Robinson G, Thompson MC, Currle DS, Eden C, et al. Subtypes of medulloblastoma have distinct developmental origins. Nature 2010; 468: 1095-1099.
4. Pei Y, Moore Colin E, Wang J, Tewari Alok K, Eroshkin A, Cho Y-J, et al. An Animal Model of MYC-Driven Medulloblastoma. Cancer Cell 2012; 21: 155-167.
5. Swartling FJ, Grimmer MR, Hackett CS, Northcott PA, Fan Q-W, Goldenberg DD, et al. Pleiotropic role for MYCN in medulloblastoma. Genes Dev 2010; 24: 1059-1072.
6. Chow Lionel ML, Endersby R, Zhu X, Rankin S, Qu C, Zhang J, et al. Cooperativity within and among Pten, p53, and Rb pathways induces high-grade astrocytoma in adult brain. Cancer Cell 2011; 19: 305-316.
7. Johnson RA, Wright KD, Poppleton H, Mohankumar KM, Finkelstein D, Pounds SB, et al. Cross-species genomics matches driver mutations and cell compartments to model ependymoma. Nature 2010; 466: 632-636.
8. Romer JT, Kimura H, Magdaleno S, Sasai K, Fuller C, Baines H, et al. Suppression of the Shh pathway using a small molecule inhibitor eliminates medulloblastoma in Ptc1()p53(-/-) mice. Cancer Cell 2004; 6: 229-240.
9. Atkinson Jennifer M, Shelat Anang A, Carcaboso Angel M, Kranenburg Tanya A, Arnold LA, Boulos N, et al. An integrated in vitro and in vivo high-throughput screen identifies treatment leads for ependymoma. Cancer Cell 2011; 20: 384-399.
10. Caponigro G, Sellers WR. Advances in the preclinical testing of cancer therapeutic hypotheses. Nat Rev Drug Discov 2011; 10: 179-187.
11. Macarron R, Banks MN, Bojanic D, Burns DJ, Cirovic DA, Garyantes T, et al. Impact of high-throughput screening in biomedical research. Nat Rev Drug Discov 2011; 10: 188-195.
12. White R, Rose K, Zon L. Zebrafish cancer: the state of the art and the path forward. Nat Rev Cancer 2013; 13: 624-636.
13. Stoletov K, Klemke R. Catch of the day: zebrafish as a human cancer model. Oncogene 2008; 27: 4509-4520.
14. Herbert J, Cavallaro T, Dwork AJ. A marker for primary choroid plexus neoplasms. Am J Pathol 1990; 136: 1317-1325.
15. Hanahan D, Weinberg Robert A. Hallmarks of cancer: the next generation. Cell 2011; 144: 646-674.
16. Lawson ND, Weinstein BM. In vivo imaging of embryonic vascular development using transgenic zebrafish. Dev Biol 2002; 248: 307-318.
17. Stoletov K, Montel V, Lester RD, Gonias SL, Klemke R. High-resolution imaging of the dynamic tumor cell-vascular interface in transparent zebrafish. Proc Natl Acad Sci USA 2007; 104: 17406-17411.
18. Pounds S, Gao CL, Johnson RA, Wright KD, Poppleton H, Finkelstein D, et al. A procedure to statistically evaluate agreement of differential expression for crossspecies genomics. Bioinformatics 2011; 27: 2098-2103.
19. Walbert T, Gilbert M, Groves M, Puduvalli V, Alfred Yung WK, Conrad C, et al. Combination of 6-thioguanine, capecitabine, and celecoxib with temozolomide or lomustine for recurrent high-grade glioma. J Neurooncol 2011; 102: 273-280.
20. Prados MD, Lamborn KR, Chang S, Burton E, Butowski N, Malec M, et al. Phase 1 study of erlotinib HCl alone and combined with temozolomide in patients with stable or recurrent malignant glioma. Neuro Oncol 2006; 8: 67-78.
21. TCGA. Comprehensive genomic characterization defines human glioblastoma genes and core pathways. Nature 2008; 455: 1061-1068.
22. Collymore C, Rasmussen S, Tolwani RJ. Gavaging adult zebrafish. J Vis Exp 2013; 11: e50691.
23. Hernan R, Fasheh R, Calabrese C, Frank AJ, Maclean KH, Allard D, et al. ERBB2 upregulates S100A4 and several other prometastatic genes in medulloblastoma. Cancer Res 2003; 63: 140-148.
24. Lacy J, Saadati H, Yu JB. Complications of brain tumors and their treatment. Hematol Oncol Clin North Am 2012; 26: 779-796.
25. Lin NU, Wefel JS, Lee EQ, Schiff D, van den Bent MJ, Soffietti R, et al. Challenges relating to solid tumour brain metastases in clinical trials, part 2: neurocognitive, neurological, and quality-of-life outcomes. A report from the RANO group. Lancet Oncol 2013; 14: e407-e416.
26. White RM, Cech J, Ratanasirintrawoot S, Lin CY, Rahl PB, Burke CJ, et al. DHODH modulates transcriptional elongation in the neural crest and melanoma. Nature 2011; 471: 518-522.
27. Hong S-K, Tsang M, Dawid IB. The mych gene is required for neural crest survival during zebrafish development. PLoS One 2008; 3: e2029.
28. Ridges S, Heaton WL, Joshi D, Choi H, Eiring A, Batchelor L, et al. Zebrafish screen identifies novel compound with selective toxicity against leukemia. Blood 2012; 119: 5621-5631.
29. Wienholds E, Schulte-Merker S, Walderich B, Plasterk RH. Target-selected inactivation of the zebrafish rag1 gene. Science 2002; 297: 99-102.
30. White RM, Sessa A, Burke C, Bowman T, LeBlanc J, Ceol C, et al. Transparent adult zebrafish as a tool for in vivo transplantation analysis. Cell Stem Cell 2008; 2: 183-189.