Facile and rapid generation of 3D chemical gradients within hydrogels for high-throughput drug screening applications

Biosensors and Bioelectronics

Volumn 59, Issue , 2014, Pages 166-173

  Ahadian, Samad ^a   Ramón Azcón, Javier ^a   Estili, Mehdi ^b   Obregón, Raquel ^a   Shiku, Hitoshi ^a   Matsue, Tomokazu ^a  

^a TOHOKU UNIVERSITY   (Japan)

^b NATIONAL INSTITUTE FOR MATERIALS SCIENCE   (Japan)

Author keywords

Chemical gradients; Dielectrophoresis; Drug release; High throughput; Hydrogels

Indexed keywords

DEXTRAN; ELECTROPHORESIS; GOLD; HYDROGELS; NANOPARTICLES; BIOMIMETIC MATERIALS; BIOMIMETICS; COST EFFECTIVENESS; YARN;

6-HYDROXYDOPAMINE (6-OHDA); CHEMICAL GRADIENTS; DRUG RELEASE; FLUORESCEIN ISOTHIOCYANATE DEXTRANS; HIGH-THROUGHPUT; NOVEL APPLICATIONS; POLYSTYRENE BEADS; RAPID GENERATIONS; HIGH THROUGHPUT; MICRO AND NANO-PARTICLE; THREEDIMENSIONAL (3-D);

THREE DIMENSIONAL; THROUGHPUT;

CARBON NANOTUBE; FLUORESCEIN ISOTHIOCYANATE DEXTRAN; GELATIN; GOLD NANOPARTICLE; METHACRYLIC ACID; OXIDOPAMINE; POLYSTYRENE; ADRENERGIC RECEPTOR BLOCKING AGENT; DEXTRAN; FLUORESCEIN ISOTHIOCYANATE; HYDROGEL;

ANIMAL CELL; ARTICLE; CELL VIABILITY; DRUG RELEASE; ELECTROPHORESIS; HIGH THROUGHPUT SCREENING; HYDROGEL; IMMOBILIZATION; MYOBLAST; NONHUMAN; PARTICLE SIZE; THREE DIMENSIONAL IMAGING; ANALOGS AND DERIVATIVES; ANIMAL; CELL SURVIVAL; CHEMISTRY; DRUG EFFECTS; DRUG SCREENING; GENETIC PROCEDURES; MOUSE; PROCEDURES;

ANIMALS; BIOSENSING TECHNIQUES; CELL SURVIVAL; DEXTRANS; DRUG EVALUATION, PRECLINICAL; ELECTROPHORESIS; FLUORESCEIN-5-ISOTHIOCYANATE; HIGH-THROUGHPUT SCREENING ASSAYS; HYDROGELS; MICE; OXIDOPAMINE; SYMPATHOLYTICS;

EID: 84898485762     PISSN: 09565663     EISSN: 18734235     Source Type: Journal    
DOI: 10.1016/j.bios.2014.03.031     Document Type: Article

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