Dimethyl sulfoxide suppresses mouse 4T1 breast cancer growth by modulating tumor-associated macrophage differentiation

Journal of Breast Cancer

Volumn 17, Issue 1, 2014, Pages 25-32

  Deng, Rui ^a   Wang, Shi Min ^a   Yin, Tao ^a   Ye, Ting Hong ^a   Shen, Guo Bo ^a   Li, Ling ^a   Zhao, Jing Yi ^a   Sang, Ya Xiong ^a   Duan, Xiao Gang ^a   Wei, Yu Quan ^a  

^a SICHUAN UNIVERSITY   (China)

Author keywords

Breast neoplasms; Dimethyl sulfoxide; Macrophage

Indexed keywords

DIMETHYL SULFOXIDE; INTERLEUKIN 10; INTERLEUKIN 12;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BREAST CANCER; CANCER GROWTH; CANCER IMMUNOTHERAPY; CELL DIFFERENTIATION; CELL VIABILITY; CONTROLLED STUDY; CYTOTOXICITY; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; FLOW CYTOMETRY; MOUSE; NONHUMAN; PROTEIN EXPRESSION; TUMOR ASSOCIATED LEUKOCYTE; TUMOR GROWTH; TUMOR MICROENVIRONMENT;

EID: 84898453167     PISSN: 17386756     EISSN: None     Source Type: Journal    
DOI: 10.4048/jbc.2014.17.1.25     Document Type: Article

References (25)

1. Huberman E, Heckman C, Langenbach R. Stimulation of differentiated functions in human melanoma cells by tumor-promoting agents and dimethyl sulfoxide. Cancer Res 1979;39(7 Pt 1):2618-3624.
2. Breitman TR, He RY. Combinations of retinoic acid with either sodium butyrate, dimethyl sulfoxide, or hexamethylene bisacetamide synergis-tically induce diferentiation of the human myeloid leukemia cell line HL60. Cancer Res 1990;50:6268-6273.
3. Levy J, Terada M, Rifind RA, Marks PA. Induction of erythroid differentiation by dimethylsulfoxide in cells infected with Friend virus: relationship to the cell cycle. Proc Natl Acad Sci U S A 1975;72:28-32.
4. Collins SJ, Ruscetti F W, Gallagher RE, Gallo RC. Terminal differentiation of human promyelocytic leukemia cells induced by dimethyl sulf-oxide and other polar compounds. Proc Natl Acad Sci U S A 1978;75: 2458-2462.
5. Ferrero D, Tarella C, Gallo E, Ruscetti FW, Breitman TR. Terminal differentiation of the human promyelocytic leukemia cell line, HL-60, in the absence of cell proliferation. Cancer Res 1982;42:4421-4426.
6. Takasaki S, Leive L. Induction by dimethyl sulfoxide of Fc fragment-mediated phagocytosis in the mouse macrophage-like cell line P388D1. Proc Natl Acad Sci U S A 1982;79:4980-4984.
7. Takenaga K. Enhanced metastatic potential of cloned low-metastatic Lewis lung carcinoma cells treated in vitro with dimethyl sulfoxide. Cancer Res 1984;44:1122-1127.
8. Fujiu K, Manabe I, Nagai R. Renal collecting duct epithelial cells regulate inflammation in tubulointerstitial damage in mice. J Clin Invest 2011;121:3425-3441.
9. Solinas G, Schiarea S, Liguori M, Fabbri M, Pesce S, Zammataro L, et al. Tumor-conditioned macrophages secrete migration-stimulating factor: a new marker for M2-polarization, influencing tumor cell motility. J Immunol 2010;185:642-652.
10. Mantovani A, Sozzani S, Locati M, Allavena P, Sica A. Macrophage polarization: tumor-associated macrophages as a paradigm for polarized M2 mononuclear phagocytes. Trends Immunol 2002;23:549-555.
11. Sica A, Schioppa T, Mantovani A, Allavena P. Tumour-associated mac-rophages are a distinct M2 polarised population promoting tumour progression: potential targets of anti-cancer therapy. Eur J Cancer 2006; 42:717-727.
12. Chen J, Ya o Y, Gong C, Yu F, Su S, Chen J, et al. CCL18 from tumor-associated macrophages promotes breast cancer metastasis via PITPNM3. Cancer Cell 2011;19:541-555.
13. Ivanović Matić S, Dinić S, Mihailović M, Grigorov I, Bogojević D, Poznanović G. Acute-phase protein expression in DMSO-intoxicated rats. Toxicol Lett 2004;147:153-159.
14. Caras I, Tucureanu C, Lerescu L, Pitica R, Melinceanu L, Neagu S, et al. Influence of tumor cell culture supernatants on macrophage functional polarization: in vitro models of macrophage-tumor environment interaction. Tumori 2011;97:647-654.
15. Wang CC, Lin SY, Lai YH, Liu YJ, Hsu YL, Chen JJ. Dimethyl sulfoxide promotes the multiple functions of the tumor suppressor HLJ1 through activator protein-1 activation in NSCLC cells. PLoS One 2012;7: e33772.
16. Pommier RF, Woltering EA, Milo G, Fletcher WS. Synergistic cytotox-icity between dimethyl sulfoxide and antineoplastic agents against ovarian cancer in vitro. Am J Obstet Gynecol 1988;159:848-852.
17. Koiri RK, Trigun SK. Dimethyl sulfoxide activates tumor necrosis factorα-p53 mediated apoptosis and down regulates D-fructose-6-phosphate-2-kinase and lactate dehydrogenase-5 in Dalton's lympho-ma in vivo. Leuk Res 2011;35:950-956.
18. Hoang BX, Tran DM, Tran HQ, Nguyen PT, Pham TD, Dang H V, et al. Dimethyl sulfoxide and sodium bicarbonate in the treatment of refractory cancer pain. J Pain Palliat Care Pharmacother 2011;25:19-24.
19. Zylber-Katz E, Glazer RI. Phospholipid- and Ca2+-dependent protein kinase activity and protein phosphorylation patterns in the differentiation of human promyelocytic leukemia cell line HL-60. Cancer Res 1985;45:5159-5164.
20. Morley P, Whitfeld J F. The differentiation inducer, dimethyl sulfoxide, transiently increases the intracellular calcium ion concentration in various cell types. J Cell Physiol 1993;156:219-225.
21. Tsao D, Morita A, Bella A Jr, Luu P, Kim YS. Differential effects of sodium butyrate, dimethyl sulfoxide, and retinoic acid on membrane-associated antigen, enzymes, and glycoproteins of human rectal adenocarci-noma cells. Cancer Res 1982;42:1052-1058.
22. Scher BM, Scher W, Robinson A, Waxman S. DNA ligase and DNase activities in mouse erythroleukemia cells during dimethyl sulfoxide-in-duced diferentiation. Cancer Res 1982;42:1300-1306.
23. Hollebeeck S, Raas T, Piront N, Schneider YJ, Toussaint O, Larondelle Y, et al. Dimethyl sulfoxide (DMSO) attenuates the inflammatory response in the in vitro intestinal Caco-2 cell model. Toxicol Lett 2011; 206:268-275.
24. Kelly KA, Hill MR, Youkhana K, Wanker F, Gimble JM. Dimethyl sulf-oxide modulates NF-kappa B and cytokine activation in lipopolysac-charide-treated murine macrophages. Infect Immun 1994;62:3122-3128.
25. Wang YC, He F, Feng F, Liu X W, Dong G Y, Qin H Y, et al. Notch signaling determines the M1 versus M2 polarization of macrophages in anti-tumor immune responses. Cancer Res 2010;70:4840-4849.