Genetic variants in nicotinic acetylcholine receptor genes jointly contribute to kidney function in American Indians: The Strong Heart Family Study

Journal of Hypertension

Volumn 32, Issue 5, 2014, Pages 1042-1049

  Zhu, Yun ^a   Yang, Jingyun ^b   Li, Shengxu ^a   Cole, Shelley A ^c   Haack, Karin ^c   Umans, Jason G ^d   Franceschini, Nora ^e   Howard, Barbara V ^d   Lee, Elisa T ^f   Zhao, Jinying ^a  

^a TULANE UNIVERSITY   (United States)

^b RUSH UNIVERSITY MEDICAL CENTER   (United States)

^c SOUTHWEST FOUNDATION FOR BIOMEDICAL RESEARCH   (United States)

^d MEDSTAR RESEARCH INSTITUTE   (United States)

^e UNIVERSITY OF NORTH CAROLINA   (United States)

^f UNIVERSITY OF OKLAHOMA HEALTH SCIENCES CENTER   (United States)

Author keywords

American Indians; cigarette smoking; genefamily analysis; joint associations; kidney function; nicotinic acetylcholine receptor genes

Indexed keywords

NICOTINIC RECEPTOR;

ADULT; ALBUMINURIA; ARTICLE; CHRONIC KIDNEY DISEASE; CONTROLLED STUDY; FEMALE; GENETIC VARIABILITY; GENOTYPE; GLOMERULUS FILTRATION RATE; HUMAN; KIDNEY FUNCTION; MAJOR CLINICAL STUDY; MALE; MICROALBUMINURIA; PRIORITY JOURNAL; RISK FACTOR; SINGLE NUCLEOTIDE POLYMORPHISM; SMOKING; AMERICAN INDIAN; GENETICS; KIDNEY FUNCTION TEST; MIDDLE AGED; PROSPECTIVE STUDY;

ADULT; FEMALE; GLOMERULAR FILTRATION RATE; HUMANS; INDIANS, NORTH AMERICAN; KIDNEY FUNCTION TESTS; MALE; MIDDLE AGED; POLYMORPHISM, SINGLE NUCLEOTIDE; PROSPECTIVE STUDIES; RECEPTORS, NICOTINIC; RISK FACTORS;

EID: 84898451799     PISSN: 02636352     EISSN: 14735598     Source Type: Journal    
DOI: 10.1097/HJH.0000000000000151     Document Type: Article

References (46)

1. Rao F, Wessel J, Wen G, Zhang L, Rana BK, Kennedy BP, et al. Renal albumin excretion: twin studies identify influences of heredity, environment, and adrenergic pathway polymorphism. Hypertension 2007; 49:1015-1031.
2. Chambers JC, Zhang W, Lord GM, van der Harst P, Lawlor DA, Sehmi JS, et al. Genetic loci influencing kidney function and chronic kidney disease. Nat Genet 2010; 42:373-375.
3. Kottgen A, Pattaro C, Boger CA, Fuchsberger C, Olden M, Glazer NL, et al. New loci associated with kidney function and chronic kidney disease. Nat Genet 2010; 42:376-384.
4. Kottgen A, Glazer NL, Dehghan A, Hwang SJ, Katz R, Li M, et al. Multiple loci associated with indices of renal function and chronic kidney disease. Nat Genet 2009; 41:712-717.
5. Pattaro C, Kottgen A, Teumer A, Garnaas M, Boger CA, Fuchsberger C, et al. Genome-wide association and functional follow-up reveals new loci for kidney function. PLoS Genet 2012; 8:e1002584.
6. Schadt EE. Molecular networks as sensors and drivers of common human diseases. Nature 2009; 461:218-223.
7. Halimi JM, Giraudeau B, Vol S, Caces E, Nivet H, Lebranchu Y, et al. Effects of current smoking and smoking discontinuation on renal function and proteinuria in the general population. Kidney Int 2000; 58:1285-1292.
8. Haroun MK, Jaar BG, Hoffman SC, Comstock GW, Klag MJ, Coresh J. Risk factors for chronic kidney disease: a prospective study of 23, 534 men and women in Washington County, Maryland. J Am Soc Nephrol 2003; 14:2934-2941.
9. Wesson DE. The relationship of cigarette smoking to end-stage renal disease. Semin Nephrol 2003; 23:317-322.
10. Daley CM, Greiner KA, Nazir N, Daley SM, Solomon CL, Braiuca SL, et al. All nations breath of life: using community-based participatory research to address health disparities in cigarette smoking among American Indians. Ethn Dis 2010; 20:334-338.
11. Narva AS, Sequist TD. Reducing health disparities in American Indians with chronic kidney disease. Semin Nephrol 2010; 30:19-25.
12. Hallan SI, Orth SR. Smoking is a risk factor in the progression to kidney failure. Kidney Int 2011; 80:516-523.
13. Briganti EM, Branley P, Chadban SJ, Shaw JE, McNeil JJ, Welborn TA, et al. Smoking is associated with renal impairment and proteinuria in the normal population: the Ausdiab Kidney Study. Am J Kidney Dis 2002; 40:704-712.
14. Ejerblad E, Fored CM, Lindblad P, Fryzek J, Dickman PW, Elinder CG, et al. Association between smoking and chronic renal failure in a nationwide population-based case-control study. J Am Soc Nephrol 2004; 15:2178-2185.
15. Orth SR. Smoking: a renal risk factor. Nephron 2000; 86:12-26.
16. Rossing P, Hougaard P, Parving HH. Risk factors for development of incipient and overt diabetic nephropathy in type 1 diabetic patients: a 10-year prospective observational study. Diabetes Care 2002; 25:859-864.
17. Bleyer AJ, Shemanski LR, Burke GL, Hansen KJ, Appel RG. Tobacco, hypertension, and vascular disease: risk factors for renal functional decline in an older population. Kidney Int 2000; 57:2072-2079.
18. Orth SR, Viedt C, Ritz E. Adverse effects of smoking in the renal patient. Tohoku J Exp Med 2001; 194:1-15.
19. Aronow WS. Heart rate and carbon monoxide level after smoking high- , low-, and nonnicotine cigarettes: a study in male patients with angina pectoris. Ann Intern Med 1971; 74:697-702.
20. Jaimes EA, Tian RX, Joshi MS, Raij L. Nicotine augments glomerular injury in a rat model of acute nephritis. Am J Nephrol 2009; 29:319-326.
21. Millar NS, Harkness PC. Assembly and trafficking of nicotinic acetylcholine receptors (review). Mol Membr Biol 2008; 25:279-292.
22. Rezonzew G, Chumley P, Feng W, Hua P, Siegal GP, Jaimes EA. Nicotine exposure and the progression of chronic kidney disease: role of the alpha7-nicotinic acetylcholine receptor. Am J Physiol Renal Physiol 2012; 303:F304-312.
23. Lee ET, Welty TK, Fabsitz R, Cowan LD, Le NA, Oopik AJ, et al. The Strong Heart Study. A study of cardiovascular disease in american indians: design and methods. Am J Epidemiol 1990; 132:1141-1155.
24. North KE, Howard BV, Welty TK, Best LG, Lee ET, Yeh JL, et al. Genetic and environmental contributions to cardiovascular disease risk in american indians: the Strong Heart Family Study. Am J Epidemiol 2003; 157:303-314.
25. Howard BV, Welty TK, Fabsitz RR, Cowan LD, Oopik AJ, Le NA, et al. Risk factors for coronary heart disease in diabetic and nondiabetic native americans. The Strong Heart Study. Diabetes 1992; 41 (Suppl 2):4-11.
26. Sosenko JM, Hu D, Welty T, Howard BV, Lee E, Robbins DC. Albuminuria in recent-onset type 2 diabetes: the Strong Heart Study. Diabetes Care 2002; 25:1078-1084.
27. Chasson AL, Grady HJ, Stanley MA. Determination of creatinine by means of automatic chemical analysis. Tech Bull Regist Med Technol 1960; 30:207-212.
28. Vasquez B, Flock EV, Savage PJ, Nagulesparan M, Bennion LJ, Baird HR, et al. Sustained reduction of proteinuria in type 2 (noninsulindependent) diabetes following diet-induced reduction of hyperglycaemia. Diabetologia 1984; 26:127-133.
29. Levey AS, Bosch JP, Lewis JB, Greene T, Rogers N, Roth D. A more accurate method to estimate glomerular filtration rate from serum creatinine: a new prediction equation. Modification of diet in renal disease study group. Ann Intern Med 1999; 130:461-470.
30. Levey AS, Coresh J, Balk E, Kausz AT, Levin A, Steffes MW, et al. National kidney foundation practice guidelines for chronic kidney disease: evaluation, classification, and stratification. Ann Intern Med 2003; 139:137-147.
31. Report of the expert committee on the diagnosis and classification of diabetes mellitus. Diabetes Care 2002; 25 (Suppl 1):s5-s20.
32. Barrett JC, Fry B, Maller J, Daly MJ. Haploview: analysis and visualization of ld and haplotype maps. Bioinformatics 2005; 21:263-265.
33. Laird NM, Horvath S, Xu X. Implementing a unified approach to familybased tests of association. Genet Epidemiol 2000; 19 (Suppl 1):S36-S42.
34. Storey JD, Tibshirani R. Statistical significance for genomewide studies. Proc Natl Acad Sci 2003; 100:9440-9445.
35. Zaykin DV, Zhivotovsky LA, Westfall PH, Weir BS. Truncated product method for combining p-values. Genet Epidemiol 2002; 22:170-185.
36. Yang J, Zhu Y, Cole SA, Haack K, Zhang Y, Beebe LA, et al. A genefamily analysis of 61 genetic variants in the nicotinic acetylcholine receptor genes for insulin resistance and type 2 diabetes in American Indians. Diabetes 2012; 61:1888-1894.
37. Gansevoort RT, Correa-Rotter R, Hemmelgarn BR, Jafar TH, Heerspink HJ, Mann JF, et al. Chronic kidney disease and cardiovascular risk: epidemiology, mechanisms, and prevention. Lancet 2013; 382:339-352.
38. Sarnak MJ, Levey AS, Schoolwerth AC, Coresh J, Culleton B, Hamm LL, et al. Kidney disease as a risk factor for development of cardiovascular disease: a statement from the American Heart Association councils on kidney in cardiovascular disease, high blood pressure research, clinical cardiology, and epidemiology and prevention. Circulation 2003; 108:2154-2169.
39. Narva AS. Reducing the burden of chronic kidney disease among american indians. Adv Chronic Kidney Dis 2008; 15:168-173.
40. Ravera M, Re M, Deferrari L, Vettoretti S, Deferrari G. Importance of blood pressure control in chronic kidney disease. J Am Soc Nephrol 2006; 17:S98-S103.
41. Low YL, Li Y, Humphreys K, Thalamuthu A, Darabi H, Wedren S, et al. Multivariant pathway association analysis reveals the importance of genetic determinants of estrogen metabolism in breast and endometrial cancer susceptibility. PLoS Genet 2010; 6:e1001012.
42. O'Seaghdha CM, Fox CS. Genome-wide association studies of chronic kidney disease: what have we learned? Nature reviews. Nephrology 2012; 8:89-99.
43. van der Vaart H, Postma DS, Timens W, ten Hacken NH. Acute effects of cigarette smoke on inflammation and oxidative stress: a review. Thorax 2004; 59:713-721.
44. Chen J, Muntner P, Hamm LL, Fonseca V, Batuman V, Whelton PK, et al. Insulin resistance and risk of chronic kidney disease in nondiabetic us adults. J Am Soc Nephrol 2003; 14:469-477.
45. DiBona GF. Neural control of the kidney: past, present, and future. Hypertension 2003; 41:621-624.
46. DiBona GF, Kopp UC. Neural control of renal function. Physiol Rev 1997; 77:75-197.