Male infertility: Decreased levels of selenium, zinc and antioxidants

Journal of Trace Elements in Medicine and Biology

Volumn 28, Issue 2, 2014, Pages 179-185

  Türk, Silver ^a   Mändar, Reet ^a   Mahlapuu, Riina ^a   Viitak, Anu ^b   Punab, Margus ^c   Kullisaar, Tiiu ^a  

^a UNIVERSITY OF TARTU   (Estonia)

^b TALLINN UNIVERSITY OF TECHNOLOGY   (Estonia)

^c TARTU UNIVERSITY HOSPITAL   (Estonia)

Author keywords

Antioxidants; Infertility; Oligozoospermia; Selenium; Zinc

Indexed keywords

EID: 84898447816     PISSN: 0946672X     EISSN: 18783252     Source Type: Journal    
DOI: 10.1016/j.jtemb.2013.12.005     Document Type: Article

References (53)

1. Kullisaar T., Türk S., Punab M., Korrovits P., Kisand K., Rehema A., et al. Oxidative stress in leucocytospermic prostatitis patients: preliminary results. Andrologia 2008, 40(3):161-172.
2. Borovkova N., Korrovits P., Ausmees K., Türk S., Jõers K., Punab M., et al. Influence of sexual intercourse on genital tract microbiota in infertile couples. Anaerobe 2011, 17(December (6)):414-418.
3. Agarwal A., Sekhon L.H. The role of antioxidant therapy in the treatment of male infertility. Hum Fertil (Camb) 2010, 13(4):217-225.
4. Gharagozloo P., Aitken R.J. The role of sperm oxidative stress in male infertility and the significance of oral antioxidant therapy. Hum Reprod 2011, 26(7):1628-1640.
5. Lavranos G., Balla M., Tzortzopoulou A., Syriou V., Angelopoulou R. Investigating ROS sources in male infertility: a common end for numerous pathways. Reprod Toxicol 2012, 34(3):298-307.
6. Jungwirth A., Giwercman A., Tournaye H., Diemer T., Kopa Z., Dohle G., et al. European Association of Urology guidelines on male infertility: the 2012 update. Eur Urol 2012, 62(2):324-332.
7. Ross C., Morriss A., Khairy M., Khalaf Y., Braude P., Coomarasamy A., et al. A systematic review of the effect of oral antioxidants on male infertility. Reprod Biomed Online 2010, 20(6):711-723.
8. Agarwal A., Allamaneni S.S. Free radicals and male reproduction. J Indian Med Assoc 2011, 109(3):184-187.
9. Krieger J.N., Nyberg L., Nickel J.C. NIH consensus definition and classification of prostatitis. JAMA 1999, 282(3):236-237.
10. Punab M., Lõivukene K., Kermes K., Mändar R. The limit of leucocytospermia from the microbiological viewpoint. Acarologia 2003, 35(October (5)):271-278.
11. World Health Organization Laboratory manual for examination of human semen and sperm-cervical mucus interaction 1999, Cambridge University Press, New York. 4th ed.
12. Paglia D.E., Valentine W.N. Studies on the quantitative and qualitative characterization of erythrocyte glutathione peroxidase. J Lab Clin Med 1967, 70(1):158-169.
13. Rauhamaa P., Kantola M., Viitak A., Kaasik T., Mussalo-Rauhamaa H. Selenium levels of Estonians. Eur J Clin Nutr 2008, 62(9):1075-1078.
14. Kullisaar T., Türk S., Punab M., Mändar R., Andrologia Oxidative stress - cause or consequence of male genital tract disorders?. Prostate 2012, 72(9):977-983.
15. Türk S., Kullisaar T. Are prostatitis symptoms associated with an isoprostane-mediated vicious circle?. Med Hypotheses 2011, 77(5):837-840.
16. Crisol L., Matorras R., Aspichueta F., Expósito A., Hernández M.L., Ruiz-Larrea M.B., et al. Glutathione peroxidase activity in seminal plasma and its relationship to classical sperm parameters and in vitro fertilization-intracytoplasmic sperm injection outcome. Fertil Steril 2012, 97(4):852-857.
17. Pasqualotto F.F., Sharma R.K., Kobayashi H., Nelson D.R., Thomas A.J., Agarwal A. Oxidative stress in normospermic men undergoing infertility evaluation. J Androl 2001, 22(2):316-322.
18. Yeung C.H., Cooper T.G., De Geyter M., De Geyter C., Rolf C., Kamischke A., et al. Studies on the origin of redox enzymes in seminal plasma and their relationship with results of in-vitro fertilization. Mol Hum Reprod 1998, 4(9):835-839.
19. Noblanc A., Kocer A., Chabory E., Vernet P., Saez F., Cadet R., et al. Glutathione peroxidases at work on epididymal spermatozoa: an example of the dual effect of reactive oxygen species on mammalian male fertilizing ability. J Androl 2011, 32(6):641-650.
20. Wu D., Cederbaum A. Alcohol, oxidative stress and free radical damage. Alcohol Res Health 2003, 27:277-284.
21. Khalil A.A., Hussien H.M., Sarhan E.M. Oxidative stress induces idiopathic infertility in Egyptian males. Afr J Biotechnol 2012, 11(6):1516-1522.
22. Potts J.M., Pasqualotto F.F. Seminal oxidative stress in patients with chronic prostatitis. Andrologia 2003, 35(5):304-308.
23. Mändar R., Kullisaar T., Borovkova N., Punab M. Sexual intercourse with leukocytospermic men may be a possible booster of oxidative stress in female partners of infertile couples. Andrology 2013, 1(3):464-468.
24. Costello L.C., Franklin R.B. Novel role of zinc in the regulation of prostate citrate metabolism and its implications in prostate cancer. Prostate 1998, 35(4):285-296.
25. Gavella M., Lipovac V., Vucić M., Sverko V. In vitro inhibition of superoxide anion production and superoxide dismutase activity by zinc in human spermatozoa. Int J Androl 1999, 22(4):266-274.
26. Atig F., Raffa M., Habib B.A., Kerkeni A., Saad A., Ajina M. Impact of seminal trace element and glutathione levels on semen quality of Tunisian infertile men. BMC Urol 2012, March (12):6.
27. Fuse H., Kazama T., Ohta S., Fujiuchi Y. Relationship between zinc concentrations in seminal plasma and various sperm parameters. Int Urol Nephrol 1999, 31(3):401-408.
28. Chia S.E., Ong C.N., Chua L.H., Ho L.M., Tay S.K. Comparison of zinc concentrations in blood and seminal plasma and the various sperm parameters between fertile and infertile men. J Androl 2000, 21(1):53-57.
29. Lewis-Jones D.I., Aird I.A., Biljan M.M., Kingsland C.R. Effects of sperm activity on zinc and fructose concentrations in seminal plasma. Hum Reprod 1996, 11(11):2465-2467.
30. Lin Y.C., Chang T.C., Tseng Y.J., Lin Y.L., Huang F.J., Kung F.T., et al. Seminal plasma zinc levels and sperm motion characteristics in infertile samples. Chang Gung Med J 2000, 23(5):260-266.
31. Dissanayake D., Wijesinghe P., Ratnasooriya W., Wimalasena S. Relationship between seminal plasma zinc and semen quality in a subfertile population. J Hum Reprod Sci 2010, 3(September (3)):124-128.
32. La Vignera S., Condorelli R.A., Vicari E., D'Aagata R., Salemi M., Calogero A.E. Hyperviscosity of semen in patients with male accessory gland infection: direct measurement with quantitative viscosimeter. Andrologia 2012, 44(Suppl. 1):556-559.
33. Deng C.H., Zheng B., She S.F. A clinical study of biological zinc for the treatment of male infertility with chronic prostatitis. Zhonghua Nan Ke Xue 2005, 11(2):127-129.
34. Sivkov A.V., Oshchepkov V.N., Evdokimov V.V., Keshishev N.G., Skabko O.V. Selzink plus study in patients with chronic non-infectious prostatitis and abnormal fertility. Urologiia 2011, 5(27-28):30-33.
35. Edström A.M., Malm J., Frohm B., Martellini J.A., Giwercman A., Mörgelin M., et al. The major bactericidal activity of human seminal plasma is zinc-dependent and derived from fragmentation of the semenogelins. J Immunol 2008, 181(September (5)):3413-3421.
36. Zaichick V.Y., Sviridova T.V., Zaichick S.V. Zinc concentration in human prostatic fluid: normal, chronic prostatitis, adenoma and cancer. Int Urol Nephrol 1996, 28(5):687-694.
37. Fair W.R., Couch J., Wehner N. Prostatic antibacterial factor. Identity and significance. Urology 1976, 7(2):169-177.
38. Johnson A.R., Munoz A., Gottlieb J.L., Jarrard D.F. High dose zinc increases hospital admissions due to genitourinary complications. J Urol 2007, 177:639-643.
39. Weeks B.S., Hanna M.S., Cooperstein D. Dietary selenium and selenoprotein function. Med Sci Monit 2012, 18(8):RA127-RA132.
40. Sabé R., Rubio R., García-Beltrán L. Reference values of selenium in plasma in population from Barcelona. Comparison with several pathologies. J Trace Elem Med Biol 2002, 16(4):231-237.
41. Zhang B., Yang L., Wang W., Li Y., Li H. Environmental selenium in the Kaschin-Beck disease area, Tibetan Plateau, China. Environ Geochem Health 2011, 33(5):495-501.
42. Ursini F., Heim S., Kiess M., Maiorino M., Roveri A., Wissing J., et al. Dual function of the selenoprotein PHGPx during sperm maturation. Science 1999, 285:1393-1396.
43. Shalini S., Bansal M.P. Co-operative effect of glutathione depletion and selenium induced oxidative stress on API and NFkB expression in testicular cells in vitro: insights to regulation of spermatogenesis. Biol Res 2007, 40(3):307-317.
44. Zwolak I., Zaporowska H. Selenium interactions and toxicity: a review, Selenium interactions and toxicity. Cell Biol Toxicol 2012, 28(1):31-46.
45. Cabañero A.I., Madrid Y., Cámara C. Selenium long-term administration and its effect on mercury toxicity. J Agric Food Chem 2006, 54(June (12)):4461-4468.
46. Akinloye O., Arowojolu A.O., Shittu O.B., Adejuwon C.A., Osotimehin B. Selenium status of idiopathic infertile Nigerian males. Biol Trace Elem Res 2005, 104(1):9-18.
47. Bleau G., Lemarbre J., Faucher G., Roberts K.D., Chapdelaine A. Semen selenium and human fertility. Fertil Steril 1984, 42(6):890-894.
48. Hawkes W.C., Turek P.J. Effects of dietary selenium on sperm motility in healthy men. J Androl 2001, 22(5):764-772.
49. Scott R., MacPherson A., Yates R.W., Hussain B., Dixon J. The effect of oral selenium supplementation on human sperm motility. Br J Urol 1998, 82(1):76-80.
50. Keskes-Ammar L., Feki-Chakroun N., Rebai T., Sahnoun Z., Ghozzi H., Hammami S., et al. Sperm oxidative stress and the effect of an oral vitamin E and selenium supplement on semen quality in infertile men. Arch Androl 2003, 49(2):83-94.
51. Moslemi M.K., Tavanbakhsh S. Selenium-vitamin E supplementation in infertile men: effects on semen parameters and pregnancy rate. Int J Gen Med 2011, 4:99-104.
52. Erel O. A novel automated method to measure total antioxidant response against potent free radical reactions. Clin Biochem. 2004, 37(February (2)):112-119.
53. Pähkla R., Zilmer M., Kullisaar T., Rägo L. Comparison of the antioxidant activity of melatonin and pinoline in vitro. J Pineal Res. 1998, 24(March (2)):96-101.