Next-generation genomic profiling of hepatocellular adenomas: A new era of individualized patient care

Cancer Cell

Volumn 25, Issue 4, 2014, Pages 409-411

  Marquardt, Jens U ^a,b   Thorgeirsson, Snorri S ^a  

^a NATIONAL CANCER INSTITUTE   (United States)

^b UNIVERSITY MEDICAL CENTER MAINZ   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

BETA CATENIN; HEPATOCYTE NUCLEAR FACTOR 1; HEPATOCYTE NUCLEAR FACTOR 1ALPHA; INTERLEUKIN 6; JANUS KINASE 1; STAT3 PROTEIN; TELOMERASE REVERSE TRANSCRIPTASE;

ADENOMA; BIOLOGICAL TRAIT; CHEMOPROPHYLAXIS; CHROMOSOMAL INSTABILITY; CHROMOSOME 12Q; CLINICAL DECISION MAKING; COPY NUMBER VARIATION; DNA METHYLATION; DOWN REGULATION; GENE MUTATION; GENOMICS; HEPATOCELLULAR ADENOMA; HETEROZYGOSITY LOSS; HUMAN; IMMUNOPHENOTYPING; IN VITRO STUDY; INFLAMMATION; LIPID METABOLISM; LIVER BIOPSY; LIVER CELL CARCINOMA; MALIGNANT TRANSFORMATION; ONCOGENE; PATIENT CARE; PRIORITY JOURNAL; SEQUENCE ANALYSIS; SHORT SURVEY; STEATOSIS;

ADENOMA, LIVER CELL; ANIMALS; CARCINOMA, HEPATOCELLULAR; CELL TRANSFORMATION, NEOPLASTIC; HUMANS; LIVER NEOPLASMS; NEOPLASM PROTEINS; PROTEIN-TYROSINE KINASES;

EID: 84898424150     PISSN: 15356108     EISSN: 18783686     Source Type: Journal    
DOI: 10.1016/j.ccr.2014.03.032     Document Type: Short Survey

References (11)

1. Bioulac-Sage P., Cubel G., Balabaud C., Zucman-Rossi J. Semin. Liver Dis. 2011, 31:91-103.
2. Bluteau O., Jeannot E., Bioulac-Sage P., Marqués J.M., Blanc J.F., Bui H., Beaudoin J.C., Franco D., Balabaud C., Laurent-Puig P., Zucman-Rossi J. Nat. Genet. 2002, 32:312-315.
3. Farges O., Ferreira N., Dokmak S., Belghiti J., Bedossa P., Paradis V. Gut 2011, 60:85-89.
4. Jones P.A., Baylin S.B. Cell 2007, 128:683-692.
5. Kan Z., Zheng H., Liu X., Li S., Barber T.D., Gong Z., Gao H., Hao K., Willard M.D., Xu J., et al. Genome Res. 2013, 23:1422-1433.
6. Nault J.C., Bioulac-Sage P., Zucman-Rossi J. Gastroenterology 2013, 144:888-902.
7. Nault J.C., Mallet M., Pilati C., Calderaro J., Bioulac-Sage P., Laurent C., Laurent A., Cherqui D., Balabaud C., Zucman-Rossi J. Nat. Commun. 2013, 4:2218.
8. Pilati C., Amessou M., Bihl M.P., Balabaud C., Nhieu J.T., Paradis V., Nault J.C., Izard T., Bioulac-Sage P., Couchy G., et al. J.Exp. Med. 2011, 208:1359-1366.
9. Pilati C., Letouzé E., Nault J.-C., Imbeaud S., Boulai A., Calderaro J., Poussin K., Franconi A., Couchy G., Morcrette G., et al. Cancer Cell 2014, 25:428-441. this issue.
10. Rebouissou S., Amessou M., Couchy G., Poussin K., Imbeaud S., Pilati C., Izard T., Balabaud C., Bioulac-Sage P., Zucman-Rossi J. Nature 2009, 457:200-204.
11. Vogelstein B., Papadopoulos N., Velculescu V.E., Zhou S., Diaz L.A., Kinzler K.W. Science 2013, 339:1546-1558.