Nucleotide-free MalK drives the transition of the maltose transporter to the inward-facing conformation

Journal of Biological Chemistry

Volumn 289, Issue 14, 2014, Pages 9844-9851

  Bao, Huan ^a   Duong, Franck ^a  

^a UNIVERSITY OF BRITISH COLUMBIA   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

FACINGS; HYDROLYSIS; MALTOSE; NUCLEOTIDES;

CYTOSOLS; INTERMEDIATE STATE; MALTOSE TRANSPORTERS; MEMBRANE DOMAIN; NANODISCS; PERIPLASM; PROTEOLIPOSOMES;

CONFORMATIONS;

ABC TRANSPORTER; ADENOSINE TRIPHOSPHATE; MALFGK2 PROTEIN; MALTOSE; UNCLASSIFIED DRUG;

AMINO TERMINAL SEQUENCE; ARTICLE; BILAYER MEMBRANE; CATALYSIS; CYTOPLASM; CYTOSOL; ESCHERICHIA COLI; NONHUMAN; PRIORITY JOURNAL; PROTEIN ASSEMBLY; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN DOMAIN; PROTEIN FUNCTION; PROTEIN HYDROLYSIS; PROTEIN MOTIF; PROTEIN PURIFICATION; PROTEIN TRANSPORT;

ABC TRANSPORTER; ATPASE; LIPIDS; MEMBRANE PROTEINS; NANODISCS; PROTEIN COMPLEXES; TRANSPORT;

ADENOSINE TRIPHOSPHATE; ATP-BINDING CASSETTE TRANSPORTERS; BIOLOGICAL TRANSPORT, ACTIVE; CATALYSIS; CYTOSOL; ESCHERICHIA COLI; ESCHERICHIA COLI PROTEINS; MONOSACCHARIDE TRANSPORT PROTEINS; MUTATION; PERIPLASM; PROTEIN STRUCTURE, QUATERNARY; PROTEIN STRUCTURE, TERTIARY;

EID: 84898078701     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M113.545525     Document Type: Article

References (25)

1. Higgins, C. F. (1992) ABC transporters: from microorganisms to man. Annu. Rev. Cell Biol. 8, 67-113
2. Hollenstein, K., Frei, D. C, and Locher, K. P. (2007) Structure of an ABC transporter in complex with its binding protein. Nature 446, 213-216
3. Rees, D. C, Johnson, E., and Lewinson, O. (2009) ABC transporters: the power to change. Nat. Rev. Mol. Cell Biol. 10, 218-227
4. Oldham, M. L., Khare, D., Quiocho, F. A., Davidson, A. L., and Chen, J. (2007) Crystal structure of a catalytic intermediate of the maltose transporter. Nature 450, 515-521
5. Khare, D., Oldham, M. L., Orelle, C, Davidson, A. L., and Chen, J. (2009) Alternating access in maltose transporter mediated by rigid-body rotations. Mol. Cell 33, 528-536
6. Daus, M. L., Landmesser, H., Schlosser, A., Müller, P., Herrmann, A., and Schneider, E. (2006) ATP induces conformational changes of periplasmic loop regions of the maltose ATP-binding cassette transporter. J. Biol. Chem. 281, 3856-3865
7. Daus, M. L., Grote, M., Müller, P., Doebber, M., Herrmann, A., Steinhoff H. J., Dassa, E., and Schneider, E. (2007) ATP-driven MalK dimer closure and reopening and conformational changes of the "EAA" motifs are crucial for function of the maltose ATP-binding cassette transporter (MalFGK2). J. Biol. Chem. 282, 22387-22396.
8. Orelle, C, Ayvaz, T., Everly, R. M., Klug, C. S., and Davidson, A. L. (2008) Both maltose-binding protein and ATP are required for nucleotide-bind-ing domain closure in the intact maltose ABC transporter. Proc. Natl. Acad. Sci. U.S.A. 105, 12837-12842
9. Bao, H., and Duong, F. (2013) ATP alone triggers the outward facing conformation of the maltose ATP-binding cassette transporter. J. Biol. Chem. 288, 3439-3448
10. Orelle, C, Alvarez, F. J., Oldham, M. L., Orelle, A., Wiley, T. E., Chen, J., and Davidson, A. L. (2010) Dynamics of a-helical subdomain rotation in the intact maltose ATP-binding cassette transporter. Proc. Natl. Acad. Sci. U.S.A. 107, 20293-20298
11. Oldham, M. L., and Chen, J. (2011) Crystal structure of the maltose transporter in a pretranslocation intermediate state. Science 332, 1202-1205
12. Bao, H., and Duong, F. (2012) Discovery of an auto-regulation mechanism for the maltose transporter MalFGK2. PLoS One 7, e34836
13. Sharma, S., Davis, J. A., Ayvaz, T., Traxler, B., and Davidson, A. L. (2005) Functional reassembly of the Escherichia coli maltose transporter following purification of a MalF-MalG subassembly. J. Bacteriol. 187, 2908-2911
14. Bao, H., Dalal, K., Wang, V., Rouiller, I., and Duong, F. (2013) The maltose ABC transporter: Action of membrane lipids on the transporter stability, coupling and ATPase activity. Biochim. Biophys. Acta 1828, 1723-1730
15. Mourez, M., Hofnung, M., and Dassa, E. (1997) Subunit interactions in ABC transporters: a conserved sequence in hydrophobic membrane proteins of periplasmic permeases defines an important site of interaction with the ATPase subunits. EMBO J. 16, 3066-3077
16. Dalal, K., and Duong, F. (2010) Reconstitution of the SecY translocon in nanodiscs. Methods Mol. Biol. 619, 145-156
17. Covitz, K. M., Panagiotidis, C. H., Hor, L. I., Reyes, M., Treptow, N. A., and Shuman, H. A. (1994) Mutations that alter the transmembrane signaling pathway in an Atp binding cassette (Abc) transporter. EMBO J. 13, 1752-1759
18. Wen, P. C., and Tajkhorshid, E. (2011) Conformational coupling of the nucleotide-binding and the transmembrane domains in ABC transporters. Biophys. J. 101, 680-690
19. Liu, P.Q., Liu, C. E., and Ames, G. F. (1999) Modulation ofATPase activity by physical disengagement of the ATP-binding domains of an ABC transporter, the histidine permease. J. Biol. Chem. 274, 18310-18318
20. DiBartolo, N., and Booth, P. J. (2011) Unravelling the folding and stability of an ABC (ATP-binding cassette) transporter. Biochem. Soc. Trans. 39, 751-760
21. Bao, H., and Duong, F. (2013) Phosphatidylglycerol directs binding and inhibitory action of EIIAGlc protein on the maltose transporter. J. Biol. Chem. 288, 23666-23674
22. Chen, S., Oldham, M. L., Davidson, A. L., and Chen, J. (2013) Carbon catabolite repression of the maltose transporter revealed by X-ray crystallography. Nature 499, 364-368
23. Panagiotidis, C. H., Reyes, M., Sievertsen, A., Boos, W., and Shuman, H. A. (1993) Characterization of the structural requirements for assembly and nucleotide binding of an ATP-binding cassette transporter. The maltose transport system of Escherichia coli. J. Biol. Chem. 268, 23685-23696
24. Fülöp, K., Barna, L., Symmons, O., Závodszky, P., and Váradi, A. (2009) Clustering ofdisease-causing mutationsonthe domain-domain interfaces of ABCC6. Biochem. Biophys. Res. Commun. 379, 706-709
25. Rabeh, W. M., Bossard, F., Xu, H., Okiyoneda, T., Bagdany, M., Mulvihill, C. M., Du, K., di Bernardo, S., Liu, Y., Konermann, L., Roldan, A., and Lukacs, G. L. (2012) Correction of both NBD1 energetics and domain interface is required to restore DeltaF508 CFTR folding and function. Cell 148, 150-163