A new diterpene from Clinopodium chinense

Natural Product Research

Volumn 28, Issue 7, 2014, Pages 467-472

  Zhong, Mingliang ^a   Wu, Haifeng ^a   Zhang, Xiaopo ^a   Sun, Guangli ^b   Sun, Guibo ^a   Yu, Shichun ^c   Xu, Xudong ^a  

^a PEKING UNION MEDICAL COLLEGE   (China)

^b HEBEI UNITED UNIVERSITY   (China)

^c Beijing Hong Tai Chi Chung Medical Technology Co Ltd   (China)

Author keywords

3 hydroxy 12 O D glucopyranosyl 8 11 13 abietatrien 7 one; Cardioprotective activity; Clinopodium chinense; Cytotoxicity

Indexed keywords

3BETA HYDROXY 12 O BETA DEXTRO GLUCOPYRANOSYL 8,11,13 ABIETATRIEN 7 ONE; DITERPENE; HESPERITIN 7 O BETA DEXTRO GLUCOPYRANOSIDE; HOMOERIODICTYOL; HYDROGEN PEROXIDE; KAEMPFEROL 3 RHAMNOPYRANOSIDE; PACLITAXEL; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER CELL CULTURE; CHEMICAL STRUCTURE; CHINESE MEDICINE; CLINOPODIUM CHINENSE; CONTROLLED STUDY; CYTOTOXICITY; DRUG ISOLATION; ELECTROSPRAY MASS SPECTROMETRY; HEART PROTECTION; HUMAN; HUMAN CELL; MEDICINAL PLANT; NONHUMAN; NUCLEAR OVERHAUSER EFFECT; PHYTOCHEMISTRY; PROTON NUCLEAR MAGNETIC RESONANCE; STEREOCHEMISTRY; TRADITIONAL MEDICINE;

CLINOPODIUM;

ANTINEOPLASTIC AGENTS, PHYTOGENIC; CARDIOTONIC AGENTS; CELL SURVIVAL; DITERPENES, ABIETANE; DRUG SCREENING ASSAYS, ANTITUMOR; DRUGS, CHINESE HERBAL; FLAVONOIDS; GLUCOSIDES; HEP G2 CELLS; HUMANS; HYDROGEN PEROXIDE; LAMIACEAE; MOLECULAR STRUCTURE; NUCLEAR MAGNETIC RESONANCE, BIOMOLECULAR;

EID: 84898057588     PISSN: 14786419     EISSN: 14786427     Source Type: Journal    
DOI: 10.1080/14786419.2013.879132     Document Type: Article

References (13)

1. Carlos A, Jaime AR, Ivan R, Tania Y, Cristina T, Guillemo SH. 2007. Gastroprotective and cytotoxic effect of semisynthetic ferruginol derivatives. J Pharm Pharmacol. 59: 289-300.
2. Chi HD, Lu JC. 2007. Advances in studies on medicinal plants in Clinopodium. J Shenyang Pharm Univ. 6: 100-110.
3. Gohar A, Gedara SR, Baraka HN. 2009. New acylated flavonol glycoside from Ceratonia siliqua L. seeds. J Med Plants Res. 3: 424-428.
4. Lewinsohn E, Berman E, Mazury Y, Gressel J. 1986. Glucosylation of exogenous flavanones by grapefruit (Citrus paradisi) cell cultures. Phytochemistry. 25: 2531-2535.
5. 20-norabietane diterpenes from the stem bark of Fraxinus sieboldiana and their biological activities. J Nat Prod. 73: 1914-1921.
6. Ma GX, Xu XD, Cao L, Yuan JQ, Yang JS, Ma LY. 2012. Cassane-type diterpenes from the seeds of Caesalpinia minax with their antineoplastic activity. Planta Med. 78: 1363-1369.
7. Nakano H, Kawada N, Yoshida M, Ono H, Iwaura R, Tonooka T. 2011. Isolation and identification of flavonoids from accumulated in proanthocyanidin-free barely. J Agric Food Chem. 59: 9581-9587.
8. 13C NMR spectral data for a novel diterpenoid from Semiaquilegia adoxoides. Magn Reson Chem. 44: 724-726.
9. Sun GB, Sun X, Wang M, Ye JX, Si JY, Xu HB, Meng XB, Qin M, Sun Y, Wang HW, Sun XB. 2012. Oxidative stress suppression by luteolin-induced heme oxygenase-1 expression. Toxicol Appl Pharmacol. 265: 229-240.
10. Sun GL, Zhang XP, Xu XD, Yang JS, Zhong ML, Yuan JQ. 2012. A new triterpene from Uncaria macrophylla and its antitumor activity. Molecules. 17: 1883-1889.
11. 2-induced apoptosis in H9c2 cardiomyoblasts. J Cell Biochem. 112: 2019-2029.
12. Yousuf S, Sudha N, Murugesan G, Enoch IVMV. 2013. Isolation of pruning from the fruit shell of Bixa orellana and the effect of β-cyclodextrin on its binding with calf thymus DNA. Carbohydr Res. 365: 46-51.
13. Zhong ML, Xu XD, Yu SC, Sun GL. 2012. Advances in studies on medicinal plants in Clinopodium Linn. Chin Tradit Herb Drugs. 43: 820-828.