Lactating and non-lactating rats differ in sensitivity to HgCl2: Protective effect of ZnCl2

Journal of Trace Elements in Medicine and Biology

Volumn 28, Issue 2, 2014, Pages 240-246

  Oliveira, Vitor Antunes ^a   Oliveira, Cláudia Sirlene ^a   Ineu, Rafael Porto ^a   Moraes Silva, Lucélia ^a   de Siqueira, Lucieli Flores ^a   Pereira, Maria Ester ^a  

^a FEDERAL UNIVERSITY OF SANTA MARIA   (Brazil)

Author keywords

Lactating rats; Mercury; Non lactating rats; Zinc; Aminolevulinic acid dehydratase

Indexed keywords

ALANINE AMINOTRANSFERASE; ASCORBIC ACID; CATALASE; CREATININE; MERCURY CHLORIDE; PORPHOBILINOGEN SYNTHASE; THIOL; UREA; ZINC CHLORIDE; CHLORIDE; MERCURIC CHLORIDE; PROTECTIVE AGENT; THIOL DERIVATIVE; ZINC DERIVATIVE;

ADULT; ALANINE AMINOTRANSFERASE BLOOD LEVEL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BIOACCUMULATION; CONTROLLED STUDY; CREATININE BLOOD LEVEL; DISEASE MARKER; DRUG EFFECT; ENZYME ACTIVITY; ENZYME INHIBITION; FEMALE; LIVER TOXICITY; MERCURIALISM; NEPHROTOXICITY; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; RAT; SENSITIVITY ANALYSIS; DRUG MECHANISM; KIDNEY; LACTATION; LIVER; ANIMAL; ANTIBODY SPECIFICITY; BLOOD; DRUG EFFECTS; ENZYMOLOGY; METABOLISM; TOXICITY; WISTAR RAT;

RATTUS;

ALANINE TRANSAMINASE; ANIMALS; ASCORBIC ACID; CATALASE; CHLORIDES; CREATININE; FEMALE; KIDNEY; LACTATION; LIVER; MERCURIC CHLORIDE; ORGAN SPECIFICITY; PORPHOBILINOGEN SYNTHASE; PROTECTIVE AGENTS; RATS, WISTAR; SULFHYDRYL COMPOUNDS; UREA; ZINC COMPOUNDS;

EID: 84898040569     PISSN: 0946672X     EISSN: 18783252     Source Type: Journal    
DOI: 10.1016/j.jtemb.2014.01.005     Document Type: Article

References (49)

1. Li P., Feng X.B., Qiu G.L., Shang L.H., Li Z.G. Mercury pollution in Asia: a review of the contaminated sites. J Hazard Mater 2009, 168:591-601.
2. Moraes-Silva L., Bueno T.M., Franciscato C., Oliveira C.S., Peixoto N.C., Pereira M.E. Mercury chloride increases hepatic alanine aminotransferase and glucose 6-phosphatase activities in newborn rats in vivo. Cell Biol Int 2012, 36:561-566.
3. Peixoto N.C., Pereira M.E. Effectiveness of ZnCl2 in protecting against nephrotoxicity induced by HgCl2 in newborn rats. Ecotoxicol Environ Saf 2007, 66:441-446.
4. 2- δ-ALA-D inhibition and Hg levels in tissues of suckling rats. Toxicol Lett 2003, 146:17-25.
5. Rocha J.B., Pereira M.E., Emanuelli T., Christofari R.S., Souza D.O. Effect of treatment with mercury chloride and lead acetate during the second stage of rapid postnatal brain growth on delta-aminolevulinic acid dehydratase (ALA-D) activity in brain, liver, kidney and blood of suckling rats. Toxicology 1995, 100:27-37.
6. 2. Basic Clin Pharmacol Toxicol 2005, 96:302-308.
7. 2. Int J Dev Neurosci 2009, 27:459-468.
8. 2 on porphobilinogen-synthase (E.C.4.2.1.24) activity and on mercury levels in rats exposed during different precocious periods of postnatal life. Cell Biol Int 2007, 31:1057-1062.
9. Franco J.L., Braga H.C., Nunes A.K., Ribas C.M., Stringari J., Silva A.P., Garcia Pomblum S.C., Moro A.M., Bohrer D., Santos A.R., Dafre A.L., Farina M. Lactational exposure to inorganic mercury: evidence of neurotoxic effects. Neurotoxicol Teratol 2007, 29:360-367.
10. Magos L., Peristianis G.C., Clarkson T.W., Snowden R.T. The effect of lactation on methylmercury intoxication. Arch Toxicol 1980, 45:143-148.
11. Carvalho M.R., Tamez R.N. Amamentação: bases científicas para a prática profissional ed. Guanabara Koogan. Rio de Janeiro 2005, 278.
12. de Freitas A.S., Funck V.R., Rotta M.S., Bohrer D., Mörschbächer V., Puntel R.L., Nogueira C.W., Farina M., Aschner M., Rocha J.B. Diphenyl diselenide, a simple organoselenium compound, decreases methylmercury-induced cerebral, hepatic and renal oxidative stress and mercury deposition in adult mice. Brain Res Bull 2009, 79:77-84.
13. Solaiman D., Jonah M.M., Miyazaki W., Ho G., Bhattacharyya M.H. Increased metallothionein in mouse liver, kidneys, and duodenum during lactation. Toxicol Sci 2001, 60:184-192.
14. Greenwood M.R., Clarkson T.W., Doherty R.A., Gates A.H., Amin-Zaki L., Elhassani S., Majeed M.A. Blood clearance half-times in lactating and nonlactating members of a population exposed to methylmercury. Environ Res 1978, 16:48-54.
15. Sandstead H.H., Zinc W.Au. Handbook on the toxicology of metals 2007, 925-947. Elsevier, Amsterdam. 3rd ed. G.F. Nordberg, B.A. Fowler, M. Nordberg, L.T. Friberg (Eds.).
16. Rooney J.P. The role of thiols, dithiols, nutritional factors and interacting ligands in the toxicology of mercury. Toxicology 2007, 234:145-156.
17. Agarwal R., Goel S.K., Chandra R., Behari J.R. Role of vitamin E in preventing acute mercury toxicity in rat. Environ Toxicol Pharmacol 2010, 29:70-78.
18. Farina M., Soares F.A., Feoli A., Roehring C., Brusque A.M., Rotta L., Perry M.L., Souza D.O., Rocha J.B. In vitro effects of selenite and mercuric chloride on liver thiobarbituric acid-reactive substances and non-protein thiols from rats: influences of dietary cholesterol and polyunsaturated and saturated fatty acids. Nutrition 2003, 19:531-535.
19. Franciscato C., Moraes-Silva L., Duarte F.A., Oliveira C.S., Ineu R.P., Flores E.M., Dressler V.L., Peixoto N.C., Pereira M.E. Delayed biochemical changes induced by mercury intoxication are prevented by zinc pre-exposure. Ecotoxicol Environ Saf 2011, 74:480-486.
20. Peixoto N.C., Serafim M.A., Flores E.M., Bebianno M.J., Pereira Metallothionein M.E. zinc, and mercury levels in tissues of young rats exposed to zinc and subsequently to mercury. Life Sci 2007, 81:1264-1271.
21. Sandstead H.H., Au Zinc W. Handbook on the toxicology of metals 2007, 925-947. Elsevier, Amsterdam. 3rd ed. G.F. Nordberg, B.A. Fowler, M. Nordberg, L.T. Friberg (Eds.).
22. Crook M.A. Zinc deficiency. Nutrition 2011, 27:1085-1086.
23. Shah D. Magnitude of zinc deficiency and efficacy of zinc. Indian J Pediatr 2011, 78:1140-1141.
24. Messaoudi I., Hammouda F., El Heni J., Baati T., Saïd K., Kerkeni A. Reversal of cadmium-induced oxidative stress in rat erythrocytes by selenium, zinc or their combination. Exp Toxicol Pathol 2010, 62:281-288.
25. Modi M., Kaul R.K., Kannan G.M., Flora S.J. Co-administration of zinc and n-acetylcysteine prevents arsenic-induced tissue oxidative stress in male rats. J Trace Elem Med Biol 2006, 20:4-197.
26. Franco J.L., Teixeira A., Meotti F.C., Ribas C.M., Stringari J., Garcia Pomblum S.C., Moro A.M., Bohrer D., Bairros A.V., Dafre A.L., Santos A.R., Farina M. Cerebellar thiol status and motor deficit after lactational exposure to methylmercury. Environ Res 2006, 102:22-28.
27. Peixoto N.C., Rocha L.C., Moraes D.P., Bebianno M.J., Dressler V.L., Flores E.M., Pereira M.E. Changes in levels of essential elements in suckling rats exposed to zinc and mercury. Chemosphere 2008, 7:1327-1332.
28. Sassa S. Delta-aminolevulinic acid dehydratase assay. Enzyme 1982, 28:133-145.
29. Ellman G.L. Tissue sulfhydryl groups. Arch Biochem Biophys 1959, 82:70-77.
30. Aebi H. Catalase in vitro. Meth Enzymol 1984, 105:121-126.
31. Roe J.H. Chemical determination of ascorbic, dehydroascorbic, and diketogulonic acids. Meth Biochem Anal 1954, 1:115-139.
32. Thomas L. Alanine aminotransferase (ALT), aspartate aminotranferase (AST). Clinical laboratory diagnostics 1998, 55-65. TH-Books Verlangsgesellschaft, Frankfurt. 1st ed. L. Thomas (Ed.).
33. Ineu R.P., Oliveira C.S., Oliveira V.A., Moraes-Silva L., Luz S.C.A., Pereira M.E. Antioxidant effect of zinc chloride against ethanol-induced gastrointestinal lesions in rats. Food Chem Toxicol 2013, 58:522-559.
34. Bradford M.M. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem 1976, 72:248-254.
35. Clarkson T.W. The toxicology of mercury. Crit Ver Clin Lab Sci 1997, 34:3-369.
36. Holmes P., James K.A., Levy L.S. Is low-level environmental mercury exposure of concern to human health?. Sci Total Environ 2009, 408:171-182.
37. Prester L., Blanuša M., Kostial K. Half-time and distribution of inorganic mercury in lactating dams and their pups. Toxicol Lett 1994, 74:66-67.
38. 2 retention in rats: 2. Chelation therapy during lactation. J Trace Elem Exp Med 1997, 10:183-190.
39. Brandão R., Santos F.W., Farina M., Zeni G., Bohrer D., Rocha J.B., Nogueira C.W. Antioxidants and metallothionein levels in mercury-treated mice. Cell Biol Toxicol 2006, 22:429-438.
40. Bhasin P., Singla N., Dhawan D.K. Protective role of zinc during aluminum-induced hepatotoxicity. Environ Toxicol 2012, arxiv:/doi:10.1002/tox.21760.
41. Lange A., Ausseil O., Segner H. Alterations of tissue glutathione levels and metallothionein mRNA in rainbow trout during single and combined exposure to cadmium and zinc. Comp Biochem Physiol C Toxicol Pharmacol 2002, 131:231-243.
42. Koster J., Biemond P., Gswaak A. Intracellular and extracellular sulfhydryl levels in rheumatoid arthritis. Ann Rheum Dis 1986, 45:44-46.
43. Boujbiha M.A., Hamden K., Guermazi F., Bouslama A., Omezzine A., Kammoun A., El Feki A. Testicular toxicity in mercuric chloride treated rats: association with oxidative stress. Reprod Toxicol 2009, 28:81-89.
44. Pal M., Ghosh M. Studies on comparative efficacy of α-linolenic acid and α-eleostearic acid on prevention of organic mercury-induced oxidative stress in kidney and liver of rat. Food Chem Toxicol 2012, 50:1066-1072.
45. Rao M.V., Chhunchha B. Protective role of melatonin against the mercury induced oxidative stress in the rat thyroid. Food Chem Toxicol 2010, 48:7-10.
46. Grosicki A., Kossakowski S. Effect of mercuric chloride poisoning on iron distribution in rats. Pol Arch Weter 1990, 30:2-91.
47. Liu L., Zhong S., Yang R., Hu H., Yu D., Zhu D., Hua Z., Shuldiner A.R., Goldstein R., Reagan W.J., Gong D.W. Expression, purification, and initial characterization of human alanine aminotransferase (ALT) isoenzyme 1 and 2 in high-five insect cells. Protein Expr Purif 2008, 60:225-231.
48. Kumar M., Sharma K., Kumar A. Spirulina fusiformis: a food supplement against mercury induced hepatictoxicity. J Health Sci 2005, 51:424-430.
49. Vedavathi M., Girish K.S., Kumar M.K. Isolation and characterization of cytosolic alanine aminotransferase isoforms from starved rat liver. Mol Cell Biochem 2004, 267:13-23.