Seminal plasma insemination during ovum-pickup--a method to increase pregnancy rate in IVF/ICSI procedure. A pilot randomized trial.

Journal of assisted reproduction and genetics

Volumn 30, Issue 4, 2013, Pages 569-574

  Chicea, Radu ^a   Ispasoiu, Florin ^b   Focsa, Mircea ^b  

^a Romania   (Romania)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; CONTROLLED STUDY; EMBRYO TRANSFER; FEMALE; FERTILITY; HUMAN; INTRACYTOPLASMIC SPERM INJECTION; PILOT STUDY; PREGNANCY; PREGNANCY RATE; PROCEDURES; RANDOMIZED CONTROLLED TRIAL; SPERM;

ADULT; EMBRYO TRANSFER; FEMALE; HUMANS; PILOT PROJECTS; PREGNANCY; PREGNANCY RATE; SEMEN; SPERM INJECTIONS, INTRACYTOPLASMIC; SPERM-OVUM INTERACTIONS;

EID: 84898018264     PISSN: None     EISSN: 15737330     Source Type: Journal    
DOI: 10.1007/s10815-013-9955-7     Document Type: Article

References (21)

1. 1. BS Bellinge CM Copeland TD Thomas RE Mazzucchelli G O’Neil MJ Cohen 1986 The influence of patient insemination on the implantation rate in an in vitro fertilization and embryo transfer program Fertil Steril 46 25 26 Bellinge BS, Copeland CM, Thomas TD, Mazzucchelli RE, O’Neil G, Cohen MJ. The influence of patient insemination on the implantation rate in an in vitro fertilization and embryo transfer program. Fertil Steril. 1986;46:25–6.
2. 2. CM Boomsma A Kavelaars MJC Eijkemans EG Lentjes BCJM Fauser CJ Heijnen 2009 Endometrial secretion analysis identifies a cytokine profile predictive of pregnancy in IVF Hum Reprod 24 6 1427 1435 19228761 1:CAS:528:DC%2BD1MXmtlKqu7w%3D 10.1093/humrep/dep011 Boomsma CM, Kavelaars A, Eijkemans MJC, Lentjes EG, Fauser BCJM, Heijnen CJ, et al. Endometrial secretion analysis identifies a cytokine profile predictive of pregnancy in IVF. Hum Reprod. 2009;24(6):1427–35.
3. 3. E Cicinelli D Ziegler de 1999 Transvaginal progesterone: evidence for a new functional “portal system” flowing from the vagina to the uterus Hum Reprod Updat 5 365 372 1:CAS:528:DyaK1MXlvVKjur8%3D 10.1093/humupd/5.4.365 Cicinelli E, de Ziegler D. Transvaginal progesterone: evidence for a new functional “portal system” flowing from the vagina to the uterus. Hum Reprod Updat. 1999;5:365–72.
4. 4. CB Coulam JJ Stern 1995 Effect of seminal plasma on implantation rates Early Pregnancy 1 33 36 9363233 1:STN:280:DyaK1c%2FivFGktw%3D%3D Coulam CB, Stern JJ. Effect of seminal plasma on implantation rates. Early Pregnancy. 1995;1:33–6.
5. 5. N Einer-Jensen R Hunter 2005 Counter-current transfer in reproductive biology Reproduction 129 9 18 15615894 1:CAS:528:DC%2BD2MXht1eltb4%3D 10.1530/rep.1.00278 Einer-Jensen N, Hunter R. Counter-current transfer in reproductive biology. Reproduction. 2005;129:9–18.
6. 6. S Fishel J Webster P Jackson B Faratian 1989 Evaluation of high vaginal insemination at oocyte recovery in patients undergoing in vitro fertilization Fertil Steril 51 135 138 2910708 1:STN:280:DyaL1M%2FptFCltg%3D%3D Fishel S, Webster J, Jackson P, Faratian B. Evaluation of high vaginal insemination at oocyte recovery in patients undergoing in vitro fertilization. Fertil Steril. 1989;51:135–8.
7. 7. WL Flowers KL Esbenshade 1993 Optimizing management of natural and artificial matings in swine J Reprod Fertil Suppl 48 217 228 8145206 1:STN:280:DyaK2c7psVClug%3D%3D Flowers WL, Esbenshade KL. Optimizing management of natural and artificial matings in swine. J Reprod Fertil Suppl. 1993;48:217–28.
8. 8. DK Gardner WB Schoolcraft 1999 Towards reproductive certainty R Jansen D Mortimer Fertility and genetics beyond Parthenon Publishing Carnforth 378 388 Gardner DK, Schoolcraft WB. Towards reproductive certainty. In: Jansen R, Mortimer D, editors. Fertility and genetics beyond. Carnforth: Parthenon Publishing; 1999. p. 378–88.
9. 9. LR Guerin JR Prins SA Robertson 2009 Regulatory T-cells and immune tolerance in pregnancy: a new target for infertility treatment? Hum Reprod 15 517 535 1:CAS:528:DC%2BD1MXhtVals7nK 10.1093/humupd/dmp004 Guerin LR, Prins JR, Robertson SA. Regulatory T-cells and immune tolerance in pregnancy: a new target for infertility treatment? Hum Reprod. 2009;15:517–35.
10. 10. S Gutsche M Wolff von T Strowitzki CJ Thaler 2003 Seminal plasma induces mRNA expression of IL-1beta, IL-6 and LIF in endometrial epithelial cells in vitro Mol Hum Reprod 9 785 791 14614040 1:CAS:528:DC%2BD3sXpvVelt7s%3D 10.1093/molehr/gag095 Gutsche S, von Wolff M, Strowitzki T, Thaler CJ. Seminal plasma induces mRNA expression of IL-1beta, IL-6 and LIF in endometrial epithelial cells in vitro. Mol Hum Reprod. 2003;9:785–91.
11. 11. M Johansson JJ Bromfield MJ Jasper SA Robertson 2004 Semen activates the female immune response during early pregnancy in mice Immunology 112 290 300 15147572 1:CAS:528:DC%2BD2cXks12hsLo%3D 10.1111/j.1365-2567.2004.01876.x Johansson M, Bromfield JJ, Jasper MJ, Robertson SA. Semen activates the female immune response during early pregnancy in mice. Immunology. 2004;112:290–300.
12. 12. RW Kelly GC Carr HO Critchley 1997 A cytokine switch induced by human seminal plasma: an immunemodulation with implications for sexually transmitted disease Hum Reprod 12 677 681 9159423 1:CAS:528:DyaK2sXjsF2hurw%3D 10.1093/humrep/12.4.677 Kelly RW, Carr GC, Critchley HO. A cytokine switch induced by human seminal plasma: an immunemodulation with implications for sexually transmitted disease. Hum Reprod. 1997;12:677–81.
13. 13. EM Kolibianakis C Bourgain P Platteau C Albano AC Steirteghem Van P Devroey 2003 Abnormal endometrial development occurs during the luteal phase of nonsupplemented donor cycles treated with recombinant follicle-stimulating hormone and gonadotropin-releasing hormone antagonists Fertil Steril 80 464 466 12909519 10.1016/S0015-0282(03)00663-0 Kolibianakis EM, Bourgain C, Platteau P, Albano C, Van Steirteghem AC, Devroey P. Abnormal endometrial development occurs during the luteal phase of nonsupplemented donor cycles treated with recombinant follicle-stimulating hormone and gonadotropin-releasing hormone antagonists. Fertil Steril. 2003;80:464–6.
14. 14. WG Ma H Song SK Das BC Paria SK Dey 2003 Estrogen is a critical determinant that specifies the duration of the window of uterine receptivity for implantation Proc Natl Acad Sci U S A 100 2963 2968 12601161 1:CAS:528:DC%2BD3sXitVaiu7w%3D 10.1073/pnas.0530162100 Ma WG, Song H, Das SK, Paria BC, Dey SK. Estrogen is a critical determinant that specifies the duration of the window of uterine receptivity for implantation. Proc Natl Acad Sci U S A. 2003;100:2963–8.
15. 15. SM Qasim A Trias M Karacan R Shelden E Kemmann 1996 Does the absence or presence of seminal fluid matter in patients undergoing ovulation induction with intrauterine insemination? Hum Reprod 11 5 1008 1010 8671379 1:STN:280:DyaK28zisVGrsw%3D%3D 10.1093/oxfordjournals.humrep.a019285 Qasim SM, Trias A, Karacan M, Shelden R, Kemmann E. Does the absence or presence of seminal fluid matter in patients undergoing ovulation induction with intrauterine insemination? Hum Reprod. 1996;11(5):1008–10.
16. 16. SA Robertson WV Ingman S O’Leary DJ Sharkey KP Tremellen 2002 Transforming growth factor beta—a mediator of immune deviation in seminal plasma J Reprod Immunol 57 109 128 12385837 1:CAS:528:DC%2BD38XnvVOmsr8%3D 10.1016/S0165-0378(02)00015-3 Robertson SA, Ingman WV, O’Leary S, Sharkey DJ, Tremellen KP. Transforming growth factor beta—a mediator of immune deviation in seminal plasma. J Reprod Immunol. 2002;57:109–28.
17. 17. SA Robertson LR Guerin M Moldenhauer JD Hayball 2009 Activating T regulatory cells for tolerance in early pregnancy-the contribution of seminal fluid J Reprod Immunol 83 109 116 19875178 1:CAS:528:DC%2BD1MXhsVynsbbJ 10.1016/j.jri.2009.08.003 Robertson SA, Guerin LR, Moldenhauer M, Hayball JD. Activating T regulatory cells for tolerance in early pregnancy-the contribution of seminal fluid. J Reprod Immunol. 2009;83:109–16.
18. 18. DJ Sharkey AM Macpherson KP Tremellen SA Robertson 2007 Seminal plasma differentially regulates inflammatory cytokine gene expression in human cervical and vaginal epithelial cells Mol Hum Reprod 13 491 501 17483528 1:CAS:528:DC%2BD2sXotl2qurY%3D 10.1093/molehr/gam028 Sharkey DJ, Macpherson AM, Tremellen KP, Robertson SA. Seminal plasma differentially regulates inflammatory cytokine gene expression in human cervical and vaginal epithelial cells. Mol Hum Reprod. 2007;13:491–501.
19. 19. KP Tremellen D Valbuena J Landeras 2000 The effect of intercourse on pregnancy rates during assisted human reproduction Hum Reprod 15 2653 2658 11098040 1:STN:280:DC%2BD3M%2FoslWlsw%3D%3D 10.1093/humrep/15.12.2653 Tremellen KP, Valbuena D, Landeras J, et al. The effect of intercourse on pregnancy rates during assisted human reproduction. Hum Reprod. 2000;15:2653–8.
20. 20. J Trowsdale AG Betz 2006 Mother’s little helpers: mechanisms of maternal-fetal tolerance Nat Immunol 7 241 246 16482172 1:CAS:528:DC%2BD28XhsVSrs7g%3D 10.1038/ni1317 Trowsdale J, Betz AG. Mother’s little helpers: mechanisms of maternal-fetal tolerance. Nat Immunol. 2006;7:241–6.
21. 21. M Wolff Von S Rosner C Thone RM Pinheiro J Jauckus T Bruckner 2009 Intravaginal and intracervical application of seminal plasma in in vitro fertilization or intracytoplasmic sperm injection treatment cycles—a double-blind, placebo-controlled, randomized pilot study Fertil Steril 91 1 167 172 10.1016/j.fertnstert.2007.11.036 Von Wolff M, Rosner S, Thone C, Pinheiro RM, Jauckus J, Bruckner T, et al. Intravaginal and intracervical application of seminal plasma in in vitro fertilization or intracytoplasmic sperm injection treatment cycles—a double-blind, placebo-controlled, randomized pilot study. Fertil Steril. 2009;91(1):167–72.