메뉴 건너뛰기




Volumn 13, Issue 6, 2014, Pages 1006-1014

Copper is a potent inhibitor of both the canonical and non-canonical NFκB pathways

Author keywords

Clioquinol; Copper; NF B; Reactive oxygen species

Indexed keywords

ACETYLCYSTEINE; CD30 ANTIGEN; CLIOQUINOL; COPPER; I KAPPA B ALPHA; IONOPHORE; PROTEIN P100; REACTIVE OXYGEN METABOLITE; X LINKED INHIBITOR OF APOPTOSIS;

EID: 84897996996     PISSN: 15384101     EISSN: 15514005     Source Type: Journal    
DOI: 10.4161/cc.27922     Document Type: Article
Times cited : (25)

References (39)
  • 1
    • 33846666110 scopus 로고    scopus 로고
    • Copper deficiency
    • PMID:17268249
    • Madsen E, Gitlin JD. Copper deficiency. Curr Opin Gastroenterol 2007; 23:187-92; PMID:17268249; http://dx.doi.org/10.1097/MOG.0b013e32801421bb
    • (2007) Curr Opin Gastroenterol , vol.23 , pp. 187-192
    • Madsen, E.1    Gitlin, J.D.2
  • 2
    • 39349112330 scopus 로고    scopus 로고
    • Mechanisms for copper acquisition, distribution and regulation
    • PMID:18277979
    • Kim BE, Nevitt T, Thiele DJ. Mechanisms for copper acquisition, distribution and regulation. Nat Chem Biol 2008; 4:176-85; PMID:18277979; http://dx.doi.org/10.1038/nchembio.72
    • (2008) Nat Chem Biol , vol.4 , pp. 176-185
    • Kim, B.E.1    Nevitt, T.2    Thiele, D.J.3
  • 3
    • 0033617578 scopus 로고    scopus 로고
    • Undetectable intracellular free copper: The requirement of a copper chaperone for superoxide dismutase
    • PMID:10221913
    • Rae TD, Schmidt PJ, Pufahl RA, Culotta VC, O'Halloran TV. Undetectable intracellular free copper: the requirement of a copper chaperone for superoxide dismutase. Science 1999; 284:805-8; PMID:10221913; http://dx.doi.org/10.1126/ science.284.5415.805
    • (1999) Science , vol.284 , pp. 805-808
    • Rae, T.D.1    Schmidt, P.J.2    Pufahl, R.A.3    Culotta, V.C.4    O'Halloran, T.V.5
  • 4
    • 77953841809 scopus 로고    scopus 로고
    • Copper in diseases and treatments, and copper-based anticancer strategies
    • PMID:19626597
    • Tisato F, Marzano C, Porchia M, Pellei M, Santini C. Copper in diseases and treatments, and copper-based anticancer strategies. Med Res Rev 2010; 30:708-49; PMID:19626597
    • (2010) Med Res Rev , vol.30 , pp. 708-749
    • Tisato, F.1    Marzano, C.2    Porchia, M.3    Pellei, M.4    Santini, C.5
  • 5
    • 58549089871 scopus 로고    scopus 로고
    • Elevated copper and oxidative stress in cancer cells as a target for cancer treatment
    • PMID:18774652
    • Gupte A, Mumper RJ. Elevated copper and oxidative stress in cancer cells as a target for cancer treatment. Cancer Treat Rev 2009; 35:32-46; PMID:18774652; http://dx.doi.org/10.1016/j.ctrv.2008.07.004
    • (2009) Cancer Treat Rev , vol.35 , pp. 32-46
    • Gupte, A.1    Mumper, R.J.2
  • 6
    • 0041928194 scopus 로고    scopus 로고
    • Tetrathiomolybdate inhibits angiogenesis and metastasis through suppression of the NFkappaB signaling cascade
    • PMID:12939395
    • Pan Q, Bao LW, Merajver SD. Tetrathiomolybdate inhibits angiogenesis and metastasis through suppression of the NFkappaB signaling cascade. Mol Cancer Res 2003; 1:701-6; PMID:12939395
    • (2003) Mol Cancer Res , vol.1 , pp. 701-706
    • Pan, Q.1    Bao, L.W.2    Merajver, S.D.3
  • 7
    • 3042680173 scopus 로고    scopus 로고
    • Copper deficiency as an anti-cancer strategy
    • PMID:15163301
    • Goodman VL, Brewer GJ, Merajver SD. Copper deficiency as an anti-cancer strategy. Endocr Relat Cancer 2004; 11:255-63; PMID:15163301; http://dx.doi.org/10.1677/erc.0.0110255
    • (2004) Endocr Relat Cancer , vol.11 , pp. 255-263
    • Goodman, V.L.1    Brewer, G.J.2    Merajver, S.D.3
  • 8
    • 84858718448 scopus 로고    scopus 로고
    • NF-κB and the link between inflammation and cancer
    • PMID:22435567
    • DiDonato JA, Mercurio F, Karin M. NF-κB and the link between inflammation and cancer. Immunol Rev 2012; 246:379-400; PMID:22435567; http://dx.doi.org/10.1111/j.1600-065X.2012.01099.x
    • (2012) Immunol Rev , vol.246 , pp. 379-400
    • DiDonato, J.A.1    Mercurio, F.2    Karin, M.3
  • 9
    • 84856213846 scopus 로고    scopus 로고
    • The diverse and complex roles of NF-κB subunits in cancer
    • PMID:22257950
    • Perkins ND. The diverse and complex roles of NF-κB subunits in cancer. Nat Rev Cancer 2012; 12:121-32; PMID:22257950
    • (2012) Nat Rev Cancer , vol.12 , pp. 121-132
    • Perkins, N.D.1
  • 10
    • 84858720357 scopus 로고    scopus 로고
    • Celebrating 25 years of NF-κ B research
    • PMID:22435544
    • Ghosh S, Hayden MS. Celebrating 25 years of NF-κ B research. Immunol Rev 2012; 246:5-13; PMID:22435544; http://dx.doi.org/10.1111/j.1600- 065X.2012.01111.x
    • (2012) Immunol Rev , vol.246 , pp. 5-13
    • Ghosh, S.1    Hayden, M.S.2
  • 11
    • 79960449149 scopus 로고    scopus 로고
    • Sam68 is required for both NF-κB activation and apoptosis signaling by the TNF receptor
    • PMID:21620750
    • Ramakrishnan P, Baltimore D. Sam68 is required for both NF-κB activation and apoptosis signaling by the TNF receptor. Mol Cell 2011; 43:167-79; PMID:21620750; http://dx.doi.org/10.1016/j.molcel.2011.05.007
    • (2011) Mol Cell , vol.43 , pp. 167-179
    • Ramakrishnan, P.1    Baltimore, D.2
  • 12
    • 0037457481 scopus 로고    scopus 로고
    • Disulfiram-mediated inhibition of NF-kappaB activity enhances cytotoxicity of 5-fluorouracil in human colorectal cancer cell lines
    • PMID:12584750
    • Wang W, McLeod HL, Cassidy J. Disulfiram-mediated inhibition of NF-kappaB activity enhances cytotoxicity of 5-fluorouracil in human colorectal cancer cell lines. Int J Cancer 2003; 104:504-11; PMID:12584750; http://dx.doi.org/10. 1002/ijc.10972
    • (2003) Int J Cancer , vol.104 , pp. 504-511
    • Wang, W.1    McLeod, H.L.2    Cassidy, J.3
  • 13
    • 77249117637 scopus 로고    scopus 로고
    • Disulfiram/copper complex inhibiting NFkappaB activity and potentiating cytotoxic effect of gemcitabine on colon and breast cancer cell lines
    • PMID:19782464
    • Guo X, Xu B, Pandey S, Goessl E, Brown J, Armesilla AL, Darling JL, Wang W. Disulfiram/copper complex inhibiting NFkappaB activity and potentiating cytotoxic effect of gemcitabine on colon and breast cancer cell lines. Cancer Lett 2010; 290:104-13; PMID:19782464; http://dx.doi.org/10.1016/j.canlet.2009. 09.002
    • (2010) Cancer Lett , vol.290 , pp. 104-113
    • Guo, X.1    Xu, B.2    Pandey, S.3    Goessl, E.4    Brown, J.5    Armesilla, A.L.6    Darling, J.L.7    Wang, W.8
  • 14
    • 33751285781 scopus 로고    scopus 로고
    • Disulfiram, a clinically used anti-alcoholism drug and copper-binding agent, induces apoptotic cell death in breast cancer cultures and xenografts via inhibition of the proteasome activity
    • PMID:17079463
    • Chen D, Cui QC, Yang H, Dou QP. Disulfiram, a clinically used anti-alcoholism drug and copper-binding agent, induces apoptotic cell death in breast cancer cultures and xenografts via inhibition of the proteasome activity. Cancer Res 2006; 66:10425-33; PMID:17079463; http://dx.doi.org/10.1158/0008- 5472.CAN-06-2126
    • (2006) Cancer Res , vol.66 , pp. 10425-10433
    • Chen, D.1    Cui, Q.C.2    Yang, H.3    Dou, Q.P.4
  • 15
    • 70350131071 scopus 로고    scopus 로고
    • Copper activation of NF-kappaB signaling in HepG2 cells
    • PMID:19747488
    • McElwee MK, Song MO, Freedman JH. Copper activation of NF-kappaB signaling in HepG2 cells. J Mol Biol 2009; 393:1013-21; PMID:19747488; http://dx.doi.org/10.1016/j.jmb.2009.08.077
    • (2009) J Mol Biol , vol.393 , pp. 1013-1021
    • McElwee, M.K.1    Song, M.O.2    Freedman, J.H.3
  • 16
    • 33745860362 scopus 로고    scopus 로고
    • Degradation of the Alzheimer disease amyloid beta-peptide by metal-dependent up-regulation of metalloprotease activity
    • PMID:16648635
    • White AR, Du T, Laughton KM, Volitakis I, Sharples RA, Xilinas ME, Hoke DE, Holsinger RM, Evin G, Cherny RA, et al. Degradation of the Alzheimer disease amyloid beta-peptide by metal-dependent up-regulation of metalloprotease activity. J Biol Chem 2006; 281:17670-80; PMID:16648635; http://dx.doi.org/10. 1074/jbc.M602487200
    • (2006) J Biol Chem , vol.281 , pp. 17670-17680
    • White, A.R.1    Du, T.2    Laughton, K.M.3    Volitakis, I.4    Sharples, R.A.5    Xilinas, M.E.6    Hoke, D.E.7    Holsinger, R.M.8    Evin, G.9    Cherny, R.A.10
  • 17
    • 45949131457 scopus 로고
    • Normal levels of trace elements in human blood or serum
    • Versieck J, Cornelis R. Normal levels of trace elements in human blood or serum. Anal Chim Acta 1980; 116:217-54; http://dx.doi.org/10.1016/S0003- 2670(01)95205-5
    • (1980) Anal Chim Acta , vol.116 , pp. 217-254
    • Versieck, J.1    Cornelis, R.2
  • 18
    • 0034672237 scopus 로고    scopus 로고
    • Differential effects of CD30 activation in anaplastic large cell lymphoma and Hodgkin disease cells
    • PMID:11110706
    • Mir SS, Richter BW, Duckett CS. Differential effects of CD30 activation in anaplastic large cell lymphoma and Hodgkin disease cells. Blood 2000; 96:4307-12; PMID:11110706
    • (2000) Blood , vol.96 , pp. 4307-4312
    • Mir, S.S.1    Richter, B.W.2    Duckett, C.S.3
  • 19
    • 34249848120 scopus 로고    scopus 로고
    • CD30 activates both the canonical and alternative NF-kappaB pathways in anaplastic large cell lymphoma cells
    • PMID:17261581
    • Wright CW, Rumble JM, Duckett CS. CD30 activates both the canonical and alternative NF-kappaB pathways in anaplastic large cell lymphoma cells. J Biol Chem 2007; 282:10252-62; PMID:17261581; http://dx.doi.org/10.1074/jbc.M608817200
    • (2007) J Biol Chem , vol.282 , pp. 10252-10262
    • Wright, C.W.1    Rumble, J.M.2    Duckett, C.S.3
  • 20
    • 0035960648 scopus 로고    scopus 로고
    • Glutathionylation of the p50 subunit of NF-kappaB: A mechanism for redox-induced inhibition of DNA binding
    • PMID:11714266
    • Pineda-Molina E, Klatt P, Vázquez J, Marina A, García de Lacoba M, Pérez-Sala D, Lamas S. Glutathionylation of the p50 subunit of NF-kappaB: a mechanism for redox-induced inhibition of DNA binding. Biochemistry 2001; 40:14134-42; PMID:11714266; http://dx.doi.org/10.1021/bi011459o
    • (2001) Biochemistry , vol.40 , pp. 14134-14142
    • Pineda-Molina, E.1    Klatt, P.2    Vázquez, J.3    Marina, A.4    García De Lacoba, M.5    Pérez-Sala, D.6    Lamas, S.7
  • 21
    • 38849199203 scopus 로고    scopus 로고
    • Shared principles in NF-kappaB signaling
    • PMID:18267068
    • Hayden MS, Ghosh S. Shared principles in NF-kappaB signaling. Cell 2008; 132:344-62; PMID:18267068; http://dx.doi.org/10.1016/j.cell.2008.01.020
    • (2008) Cell , vol.132 , pp. 344-362
    • Hayden, M.S.1    Ghosh, S.2
  • 23
    • 17144404213 scopus 로고    scopus 로고
    • Anticancer activity of the antibiotic clioquinol
    • PMID:15833873
    • Ding WQ, Liu B, Vaught JL, Yamauchi H, Lind SE. Anticancer activity of the antibiotic clioquinol. Cancer Res 2005; 65:3389-95; PMID:15833873
    • (2005) Cancer Res , vol.65 , pp. 3389-3395
    • Ding, W.Q.1    Liu, B.2    Vaught, J.L.3    Yamauchi, H.4    Lind, S.E.5
  • 24
    • 62549083952 scopus 로고    scopus 로고
    • Clioquinol inhibits the proteasome and displays preclinical activity in leukemia and myeloma
    • PMID:18754030
    • Mao X, Li X, Sprangers R, Wang X, Venugopal A, Wood T, Zhang Y, Kuntz DA, Coe E, Trudel S, et al. Clioquinol inhibits the proteasome and displays preclinical activity in leukemia and myeloma. Leukemia 2009; 23:585-90; PMID:18754030; http://dx.doi.org/10.1038/leu.2008.232
    • (2009) Leukemia , vol.23 , pp. 585-590
    • Mao, X.1    Li, X.2    Sprangers, R.3    Wang, X.4    Venugopal, A.5    Wood, T.6    Zhang, Y.7    Kuntz, D.A.8    Coe, E.9    Trudel, S.10
  • 25
    • 33847746963 scopus 로고    scopus 로고
    • Clioquinol, a therapeutic agent for Alzheimer's disease, has proteasome-inhibitory, androgen receptor-suppressing, apoptosis-inducing, and antitumor activities in human prostate cancer cells and xenografts
    • PMID:17308104
    • Chen D, Cui QC, Yang H, Barrea RA, Sarkar FH, Sheng S, Yan B, Reddy GP, Dou QP. Clioquinol, a therapeutic agent for Alzheimer's disease, has proteasome-inhibitory, androgen receptor-suppressing, apoptosis-inducing, and antitumor activities in human prostate cancer cells and xenografts. Cancer Res 2007; 67:1636-44; PMID:17308104; http://dx.doi.org/10.1158/0008-5472.CAN-06-3546
    • (2007) Cancer Res , vol.67 , pp. 1636-1644
    • Chen, D.1    Cui, Q.C.2    Yang, H.3    Barrea, R.A.4    Sarkar, F.H.5    Sheng, S.6    Yan, B.7    Reddy, G.P.8    Dou, Q.P.9
  • 26
    • 77949267166 scopus 로고    scopus 로고
    • Tumor cellular proteasome inhibition and growth suppression by 8-hydroxyquinoline and clioquinol requires their capabilities to bind copper and transport copper into cells
    • PMID:19809836
    • Zhai S, Yang L, Cui QC, Sun Y, Dou QP, Yan B. Tumor cellular proteasome inhibition and growth suppression by 8-hydroxyquinoline and clioquinol requires their capabilities to bind copper and transport copper into cells. J Biol Inorg Chem 2010; 15:259-69; PMID:19809836; http://dx.doi.org/10.1007/s00775-009-0594-5
    • (2010) J Biol Inorg Chem , vol.15 , pp. 259-269
    • Zhai, S.1    Yang, L.2    Cui, Q.C.3    Sun, Y.4    Dou, Q.P.5    Yan, B.6
  • 27
    • 84869482208 scopus 로고    scopus 로고
    • New applications of old metal-binding drugs in the treatment of human cancer
    • [Schol Ed]. (Schol Ed) PMID:22202066
    • Schmitt SM, Frezza M, Dou QP. New applications of old metal-binding drugs in the treatment of human cancer. [Schol Ed]. Front Biosci (Schol Ed) 2012; 4:375-91; PMID:22202066
    • (2012) Front Biosci , vol.4 , pp. 375-391
    • Schmitt, S.M.1    Frezza, M.2    Dou, Q.P.3
  • 28
    • 84901648175 scopus 로고    scopus 로고
    • Clioquinol and pyrrolidine dithiocarbamate complex with copper to form proteasome inhibitors and apoptosis inducers in human breast cancer cells
    • PMID:16280039
    • Daniel KG, Chen D, Orlu S, Cui QC, Miller FR, Dou QP. Clioquinol and pyrrolidine dithiocarbamate complex with copper to form proteasome inhibitors and apoptosis inducers in human breast cancer cells. Breast Cancer Res 2005; 7:R897-908; PMID:16280039; http://dx.doi.org/10.1186/bcr1322
    • (2005) Breast Cancer Res , vol.7
    • Daniel, K.G.1    Chen, D.2    Orlu, S.3    Cui, Q.C.4    Miller, F.R.5    Dou, Q.P.6
  • 29
    • 79960208716 scopus 로고    scopus 로고
    • Novel proteasome inhibitors to overcome bortezomib resistance
    • PMID:21606441
    • Ruschak AM, Slassi M, Kay LE, Schimmer AD. Novel proteasome inhibitors to overcome bortezomib resistance. J Natl Cancer Inst 2011; 103:1007-17; PMID:21606441; http://dx.doi.org/10.1093/jnci/djr160
    • (2011) J Natl Cancer Inst , vol.103 , pp. 1007-1017
    • Ruschak, A.M.1    Slassi, M.2    Kay, L.E.3    Schimmer, A.D.4
  • 30
    • 0028985190 scopus 로고
    • Phosphorylation of I kappa B alpha precedes but is not sufficient for its dissociation from NF-kappa B
    • PMID:7862124
    • DiDonato JA, Mercurio F, Karin M. Phosphorylation of I kappa B alpha precedes but is not sufficient for its dissociation from NF-kappa B. Mol Cell Biol 1995; 15:1302-11; PMID:7862124
    • (1995) Mol Cell Biol , vol.15 , pp. 1302-1311
    • DiDonato, J.A.1    Mercurio, F.2    Karin, M.3
  • 31
    • 0029033981 scopus 로고
    • Inhibition of proteasome activities and subunit-specific amino-terminal threonine modification by lactacystin
    • PMID:7732382
    • Fenteany G, Standaert RF, Lane WS, Choi S, Corey EJ, Schreiber SL. Inhibition of proteasome activities and subunit-specific amino-terminal threonine modification by lactacystin. Science 1995; 268:726-31; PMID:7732382; http://dx.doi.org/10.1126/science.7732382
    • (1995) Science , vol.268 , pp. 726-731
    • Fenteany, G.1    Standaert, R.F.2    Lane, W.S.3    Choi, S.4    Corey, E.J.5    Schreiber, S.L.6
  • 32
    • 79956032736 scopus 로고    scopus 로고
    • Clioquinol induces cytoplasmic clearance of the X-linked inhibitor of apoptosis protein (XIAP): Therapeutic indication for prostate cancer
    • PMID:21426304
    • Cater MA, Haupt Y. Clioquinol induces cytoplasmic clearance of the X-linked inhibitor of apoptosis protein (XIAP): therapeutic indication for prostate cancer. Biochem J 2011; 436:481-91; PMID:21426304; http://dx.doi.org/ 10.1042/BJ20110123
    • (2011) Biochem J , vol.436 , pp. 481-491
    • Cater, M.A.1    Haupt, Y.2
  • 34
    • 77957374335 scopus 로고    scopus 로고
    • ATM- and NEMO-dependent ELKS ubiquitination coordinates TAK1-mediated IKK activation in response to genotoxic stress
    • PMID:20932476
    • Wu ZH, Wong ET, Shi Y, Niu J, Chen Z, Miyamoto S, Tergaonkar V. ATM- and NEMO-dependent ELKS ubiquitination coordinates TAK1-mediated IKK activation in response to genotoxic stress. Mol Cell 2010; 40:75-86; PMID:20932476; http://dx.doi.org/10.1016/j.molcel.2010.09.010
    • (2010) Mol Cell , vol.40 , pp. 75-86
    • Wu, Z.H.1    Wong, E.T.2    Shi, Y.3    Niu, J.4    Chen, Z.5    Miyamoto, S.6    Tergaonkar, V.7
  • 35
    • 84867902828 scopus 로고    scopus 로고
    • Modulation of immune signalling by inhibitors of apoptosis
    • PMID:22836014
    • Beug ST, Cheung HH, LaCasse EC, Korneluk RG. Modulation of immune signalling by inhibitors of apoptosis. Trends Immunol 2012; 33:535-45; PMID:22836014; http://dx.doi.org/10.1016/j.it.2012.06.004
    • (2012) Trends Immunol , vol.33 , pp. 535-545
    • Beug, S.T.1    Cheung, H.H.2    LaCasse, E.C.3    Korneluk, R.G.4
  • 36
    • 84878190233 scopus 로고    scopus 로고
    • The effect of zinc and the role of p53 in copper-induced cellular stress responses
    • PMID:23401182
    • Formigari A, Gregianin E, Irato P. The effect of zinc and the role of p53 in copper-induced cellular stress responses. J Appl Toxicol 2013; 33:527-36; PMID:23401182; http://dx.doi.org/10.1002/jat.2854
    • (2013) J Appl Toxicol , vol.33 , pp. 527-536
    • Formigari, A.1    Gregianin, E.2    Irato, P.3
  • 37
    • 0034456918 scopus 로고    scopus 로고
    • Copper-dependent oxidative stress and neurodegeneration
    • PMID:11327325
    • Rotilio G, Carrì MT, Rossi L, Ciriolo MR. Copper-dependent oxidative stress and neurodegeneration. IUBMB Life 2000; 50:309-14; PMID:11327325; http://dx.doi.org/10.1080/15216540051081074
    • (2000) IUBMB Life , vol.50 , pp. 309-314
    • Rotilio, G.1    Carrì, M.T.2    Rossi, L.3    Ciriolo, M.R.4
  • 38
    • 67649610311 scopus 로고    scopus 로고
    • Copper chelation in cancer therapy using tetrathiomolybdate: An evolving paradigm
    • PMID:19335282
    • Khan G, Merajver S. Copper chelation in cancer therapy using tetrathiomolybdate: an evolving paradigm. Expert Opin Investig Drugs 2009; 18:541-8; PMID:19335282; http://dx.doi.org/10.1517/13543780902845622
    • (2009) Expert Opin Investig Drugs , vol.18 , pp. 541-548
    • Khan, G.1    Merajver, S.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.