Topical anti-inflammatory potential of standardized pomegranate rind extract and ellagic acid in contact dermatitis

Phytotherapy Research

Volumn 28, Issue 4, 2014, Pages 629-632

  Mo, Jiao ^a   Panichayupakaranant, Pharkphoom ^a   Kaewnopparat, Nattha ^a   Songkro, Sarunyoo ^a   Reanmongkol, Wantana ^a  

^a PRINCE OF SONGKLA UNIVERSITY   (Thailand)

Author keywords

contact dermatitis; ellagic acid; inflammation; Punica granatum; topical application

Indexed keywords

DICLOFENAC; ELLAGIC ACID; MYELOPEROXIDASE; PHENOL; POMEGRANATE EXTRACT; TRIAMCINOLONE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CONTACT DERMATITIS; CONTROLLED STUDY; CREAM; DOSE RESPONSE; EAR EDEMA; ENZYME ACTIVITY; GEL; MALE; MOUSE; NONHUMAN; TOPICAL TREATMENT;

LYTHRACEAE; PUNICA GRANATUM;

CONTACT DERMATITIS; ELLAGIC ACID; INFLAMMATION; PUNICA GRANATUM; TOPICAL APPLICATION;

ANIMALS; ANTI-INFLAMMATORY AGENTS; DERMATITIS, CONTACT; DISEASE MODELS, ANIMAL; EDEMA; ELLAGIC ACID; FRUIT; MALE; MICE; MICE, INBRED ICR; PEROXIDASE; PHENOLS; PLANT EXTRACTS; PUNICACEAE;

EID: 84897985653     PISSN: 0951418X     EISSN: 10991573     Source Type: Journal    
DOI: 10.1002/ptr.5039     Document Type: Article

References (21)

1. Adams LS, Seeram NP, Aggarwal BB, Takada Y, Sand D, Heber D,. 2006. Pomegranate juice, total pomegranate ellagitannins, and punicalagin suppress inflammatory cell signaling in colon cancer cells. J Agric Food Chem 54: 980-985.
2. Aviram M, Dornfeld L,. 2001. Pomegranate juice consumption inhibits serum angiotensin converting enzyme activity and reduces systolic blood pressure. Atherosclerosis 158: 195-198.
3. Bae J-Y, Choi J-S, Kang S-W, Lee Y-J, Park J, Kang Y-H,. 2009. Dietary compound ellagic acid alleviates skin wrinkle and inflammation induced by UV-B irradiation. Exp Dermatol 19: 182-190.
4. Bradley PP, Priebat DA, Christensen RD, Rothstein G,. 1982. Measurement of cutaneous inflammation: estimation of neutrophil content with an enzyme marker. J Invest Dermatol 78: 206-209.
5. Cabrini DA, Moresco HH, Imazu P, et al. 2011. Analysis of the potential topical anti-Inflammatory activity of Averrhoa carambola L. in mice. J Evid Based Complementary Altern Med 2011: 908059.
6. Corbett S, Daniel J, Drayton R, Field M, Steinhardt R, Garrett N,. 2010. Evaluation of the Anti-inflammatory Effects of Ellagic Acid. J Perianesth Nurs 25: 214-220.
7. De Young LM, Kheifets JB, Ballaron SJ, Young JM,. 1989. Edema and cell infiltration in the phorbol ester-treated mouse ear are temporally separate and can be differentially modulated by pharmacologic agents. Agents Actions 26: 335-241.
8. Ismail, T, Sestili, P, Akhtar, S,. 2012. Pomegranate peel and fruit extracts: A review of potential anti-inflammatory and anti-infective effects. J Ethnopharmacol 143: 397-405.
9. Jung KH, Kim MJ, Ha E, et al. 2006. Suppressive effect of Punica granatum on the production of tumor necrosis factor (Tnf) in BV2 microglial cells. Biol Pharm Bull 29: 1258-1261.
10. Lansky EP, Newman RA,. 2007. Punica granatum (pomegranate) and its potential for prevention and treatment of inflammation and cancer. J Ethnopharmacol 109: 177-206.
11. Lansky EP, Jiang W, Mo H, et al. 2005. Possible synergistic prostate cancer suppression by anatomically discrete pomegranate fractions. Invest New Drugs 23: 11-20.
12. Lim H, Park H, Kim HP,. 2004. Inhibition of contact dermatitis in animal models and suppression of proinflammatory gene expression by topically applied flavonoid, wogonin. Arch Pharmacal Res 27: 442-448.
13. Murray AR, Kisin E, Castranova V, Kommineni C, Gunther MR, Shvedova AA,. 2007 Phenol-induced in vivo oxidative stress in skin: Evidence for enhanced free radical generation, thiol oxidation, and antioxidant depletion. Chem Res Toxicol 20: 1769-1777.
14. Panichayupakaranant P, Issuriya A, Sirikatitham A, Wang W,. 2010a. Antioxidant assay-guided purification and LC determination of ellagic acid in pomegranate peel. J Chromatogr Sci 48: 456-459.
15. Panichayupakaranant P, Issuriya A, Sirikatitham A,. 2010b. Preparation method and stability of ellagic acid-rich pomegranate fruit peel extract. Pharm Biol 48: 201-205.
16. Panichayupakaranant P, Tewtrakul S, Yuenyongsawad S,. 2010c. Antibacterial, anti-inflammatory and anti-allergic activities of standardised pomegranate rind extract. Food Chem 123: 400-403.
17. Rogerio AP, Fontanari C, Melo MC, et al. 2006. Anti-inflammatory, analgesic and anti-oedematous effects of Lafoensia pacari extract and ellagic acid. J Pharm Pharmacol 58: 1265-1273.
18. Saraiva RA, Araruna MKA, Oliveira RC, et al. 2011. Topical anti-inflammatory effect of Caryocar coriaceum Wittm. (Caryocaraceae) fruit pulp fixed oil on mice ear edema induced by different irritant agents. J Ethnopharmacol 136: 504-510.
19. Schaerli P, Britschgi M, Keller M, et al. 2004. Characterization of human T cells that regulate neutrophilic skin inflammation. J Immunol 173: 2151-2158.
20. Schubert SY, Lansky EP, Neeman I,. 1999. Antioxidant and eicosanoid enzyme inhibition properties of pomegranate seed oil and fermented juice flavonoids. J Ethnopharmacol 66: 11-17.
21. Wilmer JL, Burleson FG, Kayama F, Kanno J, Luster MI,. 1994. Cytokine induction in human epidermal keratinocytes exposed to contact irritants and its relation to chemical-induced inflammation in mouse skin. J Invest Dermatol 102: 915-922.