High content image analysis identifies novel regulators of synaptogenesis in a high-throughput RNAi screen of primary neurons

PLoS ONE

Volumn 9, Issue 3, 2014, Pages

  Nieland, Thomas J F ^a   Logan, David J ^a   Saulnier, Jessica ^b   Lam, Daniel ^a   Johnson, Caroline ^b   Root, David E ^a   Carpenter, Anne E ^a   Sabatini, Bernardo L ^b  

^a BROAD INSTITUTE OF MIT AND HARVARD   (United States)

^b HOWARD HUGHES MEDICAL INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

RNA; SHORT HAIRPIN RNA; SMALL INTERFERING RNA;

ALZHEIMER DISEASE; ANIMAL TISSUE; ARTICLE; AUTISM; BRAIN CELL CULTURE; COGNITION; DENDRITE; DEVELOPMENTAL DISORDER; ELECTROPORATION; GENE EXPRESSION; HIGH THROUGHPUT SCREENING; HUMAN; IMAGE ANALYSIS; INTELLECTUAL IMPAIRMENT; LENTIVIRINAE; MOUSE; NEUROLOGIC DISEASE; NONHUMAN; REPRODUCIBILITY; RNA INTERFERENCE; SYNAPSE; SYNAPTOGENESIS; ALGORITHM; ANIMAL; FLUORESCENCE MICROSCOPY; GENE EXPRESSION REGULATION; GENETICS; LABORATORY AUTOMATION; METABOLISM; NERVE CELL;

ALGORITHMS; ANIMALS; AUTOMATION, LABORATORY; GENE EXPRESSION REGULATION; HIGH-THROUGHPUT SCREENING ASSAYS; MICE; MICROSCOPY, FLUORESCENCE; NEURONS; RNA INTERFERENCE; RNA, SMALL INTERFERING; SYNAPSES;

EID: 84897973093     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0091744     Document Type: Article

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