-
1
-
-
34250648038
-
Interleukin-21: an interleukin-2 dependent player in rejection processes
-
Baan, C.C., A.H. Balk, I.E. Dijke, S.S. Korevaar, A.M. Peeters, R.P. de Kuiper, M. Klepper, P.E. Zondervan, L.A. Maat, and W. Weimar. 2007. Interleukin-21: an interleukin-2 dependent player in rejection processes. Transplantation. 83:1485-1492. http://dx.doi.org/10.1097/01.tp.0000264998.23349.54
-
(2007)
Transplantation.
, vol.83
, pp. 1485-1492
-
-
Baan, C.C.1
Balk, A.H.2
Dijke, I.E.3
Korevaar, S.S.4
Peeters, A.M.5
de Kuiper, R.P.6
Klepper, M.7
Zondervan, P.E.8
Maat, L.A.9
Weimar, W.10
-
2
-
-
0027263342
-
Mouse strain differences in susceptibility to cerebral ischemia are related to cerebral vascular anatomy
-
Barone, F.C., D.J. Knudsen, A.H. Nelson, G.Z. Feuerstein, and R.N. Willette. 1993. Mouse strain differences in susceptibility to cerebral ischemia are related to cerebral vascular anatomy. J. Cereb. Blood Flow Metab. 13:683-692. http://dx.doi.org/10.1038/jcbfm.1993.87
-
(1993)
J. Cereb. Blood Flow Metab.
, vol.13
, pp. 683-692
-
-
Barone, F.C.1
Knudsen, D.J.2
Nelson, A.H.3
Feuerstein, G.Z.4
Willette, R.N.5
-
3
-
-
0030976856
-
Tumor necrosis factor-alpha. A mediator of focal ischemic brain injury.
-
Barone, F.C., B. Arvin, R.F. White, A. Miller, C.L. Webb, R.N. Willette, P.G. Lysko, and G.Z. Feuerstein. 1997. Tumor necrosis factor-alpha. A mediator of focal ischemic brain injury. Stroke. 28:1233-1244. http://dx.doi.org/10.1161/01.STR.28.6.1233
-
(1997)
Stroke.
, vol.28
, pp. 1233-1244
-
-
Barone, F.C.1
Arvin, B.2
White, R.F.3
Miller, A.4
Webb, C.L.5
Willette, R.N.6
Lysko, P.G.7
Feuerstein, G.Z.8
-
4
-
-
84876040340
-
Interleukin-21 (IL-21) synergizes with IL-2 to enhance T-cell receptor-induced human T-cell proliferation and counteracts IL-2/transforming growth factor-?-induced regulatory T-cell development
-
Battaglia, A., A. Buzzonetti, C. Baranello, M. Fanelli, M. Fossati, V. Catzola, G. Scambia, and A. Fattorossi. 2013. Interleukin-21 (IL-21) synergizes with IL-2 to enhance T-cell receptor-induced human T-cell proliferation and counteracts IL-2/transforming growth factor-?-induced regulatory T-cell development. Immunology. 139:109-120. http://dx.doi.org/10.1111/imm.12061
-
(2013)
Immunology.
, vol.139
, pp. 109-120
-
-
Battaglia, A.1
Buzzonetti, A.2
Baranello, C.3
Fanelli, M.4
Fossati, M.5
Catzola, V.6
Scambia, G.7
Fattorossi, A.8
-
5
-
-
65549130913
-
Temporal and spatial dynamics of cerebral immune cell accumulation in stroke
-
Gelderblom, M., F. Leypoldt, K. Steinbach, D. Behrens, C.U. Choe, D.A. Siler, T.V. Arumugam, E. Orthey, C. Gerloff, E. Tolosa, and T. Magnus. 2009. Temporal and spatial dynamics of cerebral immune cell accumulation in stroke. Stroke. 40:1849-1857. http://dx.doi.org/10.1161/STROKEAHA.108.534503
-
(2009)
Stroke.
, vol.40
, pp. 1849-1857
-
-
Gelderblom, M.1
Leypoldt, F.2
Steinbach, K.3
Behrens, D.4
Choe, C.U.5
Siler, D.A.6
Arumugam, T.V.7
Orthey, E.8
Gerloff, C.9
Tolosa, E.10
Magnus, T.11
-
6
-
-
84868602402
-
Neutralization of the IL-17 axis diminishes neutrophil invasion and protects from ischemic stroke
-
Gelderblom, M., A. Weymar, C. Bernreuther, J. Velden, P. Arunachalam, K. Steinbach, E. Orthey, T.V. Arumugam, F. Leypoldt, O. Simova, et al. 2012. Neutralization of the IL-17 axis diminishes neutrophil invasion and protects from ischemic stroke. Blood. 120:3793-3802. http://dx.doi.org/10.1182/blood-2012-02-412726
-
(2012)
Blood.
, vol.120
, pp. 3793-3802
-
-
Gelderblom, M.1
Weymar, A.2
Bernreuther, C.3
Velden, J.4
Arunachalam, P.5
Steinbach, K.6
Orthey, E.7
Arumugam, T.V.8
Leypoldt, F.9
Simova, O.10
-
7
-
-
58149503895
-
Expression of interleukin-21, interleukin-21 receptor alpha and related type I cytokines by intravascular graft leukocytes during acute renal allograft rejection
-
Hecker, A., A. Kaufmann, M. Hecker, W. Padberg, and V. Grau. 2009. Expression of interleukin-21, interleukin-21 receptor alpha and related type I cytokines by intravascular graft leukocytes during acute renal allograft rejection. Immunobiology. 214:41-49. http://dx.doi.org/10.1016/j.imbio.2008.04.004
-
(2009)
Immunobiology.
, vol.214
, pp. 41-49
-
-
Hecker, A.1
Kaufmann, A.2
Hecker, M.3
Padberg, W.4
Grau, V.5
-
8
-
-
0037101645
-
Interleukin-18 involvement in hypoxic-ischemic brain injury
-
Hedtjärn, M., A.L. Leverin, K. Eriksson, K. Blomgren, C. Mallard, and H. Hagberg. 2002. Interleukin-18 involvement in hypoxic-ischemic brain injury. J. Neurosci. 22:5910-5919.
-
(2002)
J. Neurosci.
, vol.22
, pp. 5910-5919
-
-
Hedtjärn, M.1
Leverin, A.L.2
Eriksson, K.3
Blomgren, K.4
Mallard, C.5
Hagberg, H.6
-
9
-
-
70449717532
-
TLR3 ligand polyinosinic:polycytidylic acid induces IL-17A and IL-21 synthesis in human Th cells
-
Holm, C.K., C.C. Petersen, M. Hvid, L. Petersen, S.R. Paludan, B. Deleuran, and M. Hokland. 2009. TLR3 ligand polyinosinic:polycytidylic acid induces IL-17A and IL-21 synthesis in human Th cells. J. Immunol. 183:4422-4431. http://dx.doi.org/10.4049/jimmunol.0804318
-
(2009)
J. Immunol.
, vol.183
, pp. 4422-4431
-
-
Holm, C.K.1
Petersen, C.C.2
Hvid, M.3
Petersen, L.4
Paludan, S.R.5
Deleuran, B.6
Hokland, M.7
-
10
-
-
65249180981
-
A positive feedback loop of IL-21 signaling provoked by homeostatic CD4+CD25-T cell expansion is essential for the development of arthritis in autoimmune K/BxN mice
-
Jang, E., S.H. Cho, H. Park, D.J. Paik, J.M. Kim, and J. Youn. 2009. A positive feedback loop of IL-21 signaling provoked by homeostatic CD4+CD25-T cell expansion is essential for the development of arthritis in autoimmune K/BxN mice. J. Immunol. 182:4649-4656. http://dx.doi.org/10.4049/jimmunol.0804350
-
(2009)
J. Immunol.
, vol.182
, pp. 4649-4656
-
-
Jang, E.1
Cho, S.H.2
Park, H.3
Paik, D.J.4
Kim, J.M.5
Youn, J.6
-
11
-
-
78049380676
-
Excessive Na+/H+ exchange in disruption of dendritic Na+ and Ca2+ homeostasis and mitochondrial dysfunction following in vitro ischemia
-
Kintner, D.B., X. Chen, J. Currie, V. Chanana, P. Ferrazzano, A. Baba, T. Matsuda, M. Cohen, J. Orlowski, S.Y. Chiu, et al. 2010. Excessive Na+/H+ exchange in disruption of dendritic Na+ and Ca2+ homeostasis and mitochondrial dysfunction following in vitro ischemia. J. Biol. Chem. 285:35155-35168. http://dx.doi.org/10.1074/jbc. M110.101212
-
(2010)
J. Biol. Chem.
, vol.285
, pp. 35155-35168
-
-
Kintner, D.B.1
Chen, X.2
Currie, J.3
Chanana, V.4
Ferrazzano, P.5
Baba, A.6
Matsuda, T.7
Cohen, M.8
Orlowski, J.9
Chiu, S.Y.10
-
12
-
-
77952557777
-
Early detrimental T-cell effects in experimental cerebral ischemia are neither related to adaptive immunity nor thrombus formation
-
Kleinschnitz, C., N. Schwab, P. Kraft, I. Hagedorn, A. Dreykluft, T. Schwarz, M. Austinat, B. Nieswandt, H. Wiendl, and G. Stoll. 2010. Early detrimental T-cell effects in experimental cerebral ischemia are neither related to adaptive immunity nor thrombus formation. Blood. 115:3835-3842. http://dx.doi.org/10.1182/blood-2009-10-249078
-
(2010)
Blood.
, vol.115
, pp. 3835-3842
-
-
Kleinschnitz, C.1
Schwab, N.2
Kraft, P.3
Hagedorn, I.4
Dreykluft, A.5
Schwarz, T.6
Austinat, M.7
Nieswandt, B.8
Wiendl, H.9
Stoll, G.10
-
13
-
-
84873019070
-
Regulatory T cells are strong promoters of acute ischemic stroke in mice by inducing dysfunction of the cerebral microvasculature
-
Kleinschnitz, C., P. Kraft, A. Dreykluft, I. Hagedorn, K. Göbel, M.K. Schuhmann, F. Langhauser, X. Helluy, T. Schwarz, S. Bittner, et al. 2013. Regulatory T cells are strong promoters of acute ischemic stroke in mice by inducing dysfunction of the cerebral microvasculature. Blood. 121:679-691. http://dx.doi.org/10.1182/blood-2012-04-426734
-
(2013)
Blood.
, vol.121
, pp. 679-691
-
-
Kleinschnitz, C.1
Kraft, P.2
Dreykluft, A.3
Hagedorn, I.4
Göbel, K.5
Schuhmann, M.K.6
Langhauser, F.7
Helluy, X.8
Schwarz, T.9
Bittner, S.10
-
14
-
-
34547232503
-
IL-21 initiates an alternative pathway to induce proinflammatory T(H)17 cells
-
Korn, T., E. Bettelli, W. Gao, A. Awasthi, A. Jäger, T.B. Strom, M. Oukka, and V.K. Kuchroo. 2007. IL-21 initiates an alternative pathway to induce proinflammatory T(H)17 cells. Nature. 448:484-487. http://dx.doi.org/10.1038/nature05970
-
(2007)
Nature.
, vol.448
, pp. 484-487
-
-
Korn, T.1
Bettelli, E.2
Gao, W.3
Awasthi, A.4
Jäger, A.5
Strom, T.B.6
Oukka, M.7
Kuchroo, V.K.8
-
15
-
-
59649123881
-
Regulatory T cells are key cerebroprotective immunomodulators in acute experimental stroke
-
Liesz, A., E. Suri-Payer, C. Veltkamp, H. Doerr, C. Sommer, S. Rivest, T. Giese, and R. Veltkamp. 2009. Regulatory T cells are key cerebroprotective immunomodulators in acute experimental stroke. Nat. Med. 15:192-199. http://dx.doi.org/10.1038/nm.1927
-
(2009)
Nat. Med.
, vol.15
, pp. 192-199
-
-
Liesz, A.1
Suri-Payer, E.2
Veltkamp, C.3
Doerr, H.4
Sommer, C.5
Rivest, S.6
Giese, T.7
Veltkamp, R.8
-
16
-
-
0024494427
-
Reversible middle cerebral artery occlusion without craniectomy in rats
-
Longa, E.Z., P.R. Weinstein, S. Carlson, and R. Cummins. 1989. Reversible middle cerebral artery occlusion without craniectomy in rats. Stroke. 20:84-91. http://dx.doi.org/10.1161/01.STR.20.1.84
-
(1989)
Stroke.
, vol.20
, pp. 84-91
-
-
Longa, E.Z.1
Weinstein, P.R.2
Carlson, S.3
Cummins, R.4
-
18
-
-
0033755358
-
Differences in vulnerability to permanent focal cerebral ischemia among 3 common mouse strains
-
Majid, A., Y.Y. He, J.M. Gidday, S.S. Kaplan, E.R. Gonzales, T.S. Park, J.D. Fenstermacher, L. Wei, D.W. Choi, and C.Y. Hsu. 2000. Differences in vulnerability to permanent focal cerebral ischemia among 3 common mouse strains. Stroke. 31:2707-2714. http://dx.doi.org/10.1161/01.STR.31.11.2707
-
(2000)
Stroke.
, vol.31
, pp. 2707-2714
-
-
Majid, A.1
He, Y.Y.2
Gidday, J.M.3
Kaplan, S.S.4
Gonzales, E.R.5
Park, T.S.6
Fenstermacher, J.D.7
Wei, L.8
Choi, D.W.9
Hsu, C.Y.10
-
19
-
-
79952403576
-
Interleukin-21 is critically required in autoimmune and allogeneic responses to islet tissue in murine models
-
McGuire, H.M., S. Walters, A. Vogelzang, C.M. Lee, K.E. Webster, J. Sprent, D. Christ, S. Grey, and C. King. 2011. Interleukin-21 is critically required in autoimmune and allogeneic responses to islet tissue in murine models. Diabetes. 60:867-875. http://dx.doi.org/10.2337/db10-1157
-
(2011)
Diabetes.
, vol.60
, pp. 867-875
-
-
McGuire, H.M.1
Walters, S.2
Vogelzang, A.3
Lee, C.M.4
Webster, K.E.5
Sprent, J.6
Christ, D.7
Grey, S.8
King, C.9
-
20
-
-
80052210855
-
Ischaemic stroke: a thrombo-inflammatory disease? J
-
Nieswandt, B., C. Kleinschnitz, and G. Stoll. 2011. Ischaemic stroke: a thrombo-inflammatory disease? J. Physiol. 589:4115-4123.
-
(2011)
Physiol.
, vol.589
, pp. 4115-4123
-
-
Nieswandt, B.1
Kleinschnitz, C.2
Stoll, G.3
-
21
-
-
33846196712
-
IL-21 counteracts the regulatory T cell-mediated suppression of human CD4+ T lymphocytes
-
Peluso, I., M.C. Fantini, D. Fina, R. Caruso, M. Boirivant, T.T. MacDonald, F. Pallone, and G. Monteleone. 2007. IL-21 counteracts the regulatory T cell-mediated suppression of human CD4+ T lymphocytes. J. Immunol. 178:732-739.
-
(2007)
J. Immunol.
, vol.178
, pp. 732-739
-
-
Peluso, I.1
Fantini, M.C.2
Fina, D.3
Caruso, R.4
Boirivant, M.5
MacDonald, T.T.6
Pallone, F.7
Monteleone, G.8
-
22
-
-
68349160698
-
Pivotal role of cerebral interleukin- 17-producing gammadeltaT cells in the delayed phase of ischemic brain injury
-
Shichita, T., Y. Sugiyama, H. Ooboshi, H. Sugimori, R. Nakagawa, I. Takada, T. Iwaki, Y. Okada, M. Iida, D.J. Cua, et al. 2009. Pivotal role of cerebral interleukin- 17-producing gammadeltaT cells in the delayed phase of ischemic brain injury. Nat. Med. 15:946-950. http://dx.doi.org/10.1038/nm.1999
-
(2009)
Nat. Med.
, vol.15
, pp. 946-950
-
-
Shichita, T.1
Sugiyama, Y.2
Ooboshi, H.3
Sugimori, H.4
Nakagawa, R.5
Takada, I.6
Iwaki, T.7
Okada, Y.8
Iida, M.9
Cua, D.J.10
-
23
-
-
84863133298
-
IL-21 promotes the pathologic immune response to pneumovirus infection
-
Spolski, R., L. Wang, C.K. Wan, C.A. Bonville, J.B. Domachowske, H.P. Kim, Z. Yu, and W.J. Leonard. 2012. IL-21 promotes the pathologic immune response to pneumovirus infection. J. Immunol. 188:1924-1932. http://dx.doi.org/10.4049/jimmunol.1100767
-
(2012)
J. Immunol.
, vol.188
, pp. 1924-1932
-
-
Spolski, R.1
Wang, L.2
Wan, C.K.3
Bonville, C.A.4
Domachowske, J.B.5
Kim, H.P.6
Yu, Z.7
Leonard, W.J.8
-
24
-
-
84871928577
-
Regulatory T cells accumulate and proliferate in the ischemic hemisphere for up to 30 days after MCAO
-
Stubbe, T., F. Ebner, D. Richter, O. Engel, J. Klehmet, G. Royl, A. Meisel, R. Nitsch, C. Meisel, and C. Brandt. 2013. Regulatory T cells accumulate and proliferate in the ischemic hemisphere for up to 30 days after MCAO. J. Cereb. Blood Flow Metab. 33:37-47. http://dx.doi.org/10.1038/jcbfm.2012.128
-
(2013)
J. Cereb. Blood Flow Metab.
, vol.33
, pp. 37-47
-
-
Stubbe, T.1
Ebner, F.2
Richter, D.3
Engel, O.4
Klehmet, J.5
Royl, G.6
Meisel, A.7
Nitsch, R.8
Meisel, C.9
Brandt, C.10
-
25
-
-
0025228733
-
A semiautomated method for measuring brain infarct volume
-
Swanson, R.A., M.T. Morton, G. Tsao-Wu, R.A. Savalos, C. Davidson, and F.R. Sharp. 1990. A semiautomated method for measuring brain infarct volume. J. Cereb. Blood Flow Metab. 10:290-293. http://dx.doi.org/10.1038/jcbfm.1990.47
-
(1990)
J. Cereb. Blood Flow Metab.
, vol.10
, pp. 290-293
-
-
Swanson, R.A.1
Morton, M.T.2
Tsao-Wu, G.3
Savalos, R.A.4
Davidson, C.5
Sharp, F.R.6
-
26
-
-
79951837408
-
IL-21 and IL-21 receptor expression in lymphocytes and neurons in multiple sclerosis brain
-
Tzartos, J.S., M.J. Craner, M.A. Friese, K.B. Jakobsen, J. Newcombe, M.M. Esiri, and L. Fugger. 2011. IL-21 and IL-21 receptor expression in lymphocytes and neurons in multiple sclerosis brain. Am. J. Pathol. 178:794-802. http://dx.doi.org/10.1016/j.ajpath.2010.10.043
-
(2011)
Am. J. Pathol.
, vol.178
, pp. 794-802
-
-
Tzartos, J.S.1
Craner, M.J.2
Friese, M.A.3
Jakobsen, K.B.4
Newcombe, J.5
Esiri, M.M.6
Fugger, L.7
-
27
-
-
84886082042
-
Increased production of interleukin-21, but not interleukin-17A, in the small intestine characterizes pediatric celiac disease
-
van Leeuwen, M.A., D.J. Lindenbergh-Kortleve, H.C. Raatgeep, L.F. de Ruiter, R.R. de Krijger, M. Groeneweg, J.C. Escher, and J.N. Samsom. 2013. Increased production of interleukin-21, but not interleukin-17A, in the small intestine characterizes pediatric celiac disease. Mucosal Immunol. 6:1202-1213. http://dx.doi.org/10.1038/mi.2013.19
-
(2013)
Mucosal Immunol.
, vol.6
, pp. 1202-1213
-
-
van Leeuwen, M.A.1
Lindenbergh-Kortleve, D.J.2
Raatgeep, H.C.3
de Ruiter, L.F.4
de Krijger, R.R.5
Groeneweg, M.6
Escher, J.C.7
Samsom, J.N.8
-
28
-
-
78649469085
-
Th17 promotes acute rejection following liver transplantation in rats
-
Xie, X.J., Y.F. Ye, L. Zhou, H.Y. Xie, G.P. Jiang, X.W. Feng, Y. He, Q.F. Xie, and S.S. Zheng. 2010. Th17 promotes acute rejection following liver transplantation in rats. J. Zhejiang Univ. Sci. B. 11:819-827. http://dx.doi.org/10.1631/jzus. B1000030
-
(2010)
J. Zhejiang Univ. Sci. B.
, vol.11
, pp. 819-827
-
-
Xie, X.J.1
Ye, Y.F.2
Zhou, L.3
Xie, H.Y.4
Jiang, G.P.5
Feng, X.W.6
He, Y.7
Xie, Q.F.8
Zheng, S.S.9
-
29
-
-
77954482190
-
Leukocyte recruitment and ischemic brain injury
-
Yilmaz, G., and D.N. Granger. 2010. Leukocyte recruitment and ischemic brain injury. Neuromolecular Med. 12:193-204. http://dx.doi.org/10.1007/s12017-009-8074-1
-
(2010)
Neuromolecular Med.
, vol.12
, pp. 193-204
-
-
Yilmaz, G.1
Granger, D.N.2
-
30
-
-
33646454450
-
Role of T lymphocytes and interferon-gamma in ischemic stroke
-
Yilmaz, G., T.V. Arumugam, K.Y. Stokes, and D.N. Granger. 2006. Role of T lymphocytes and interferon-gamma in ischemic stroke. Circulation. 113:2105-2112. http://dx.doi.org/10.1161/CIRCULATIONAHA.105.593046
-
(2006)
Circulation.
, vol.113
, pp. 2105-2112
-
-
Yilmaz, G.1
Arumugam, T.V.2
Stokes, K.Y.3
Granger, D.N.4
|