An innovative three-dimensional model of normal human skin to study the proinflammatory psoriatic effects of tumor necrosis factor-alpha and interleukin-17

Cytokine

Volumn 68, Issue 1, 2014, Pages 1-8

  Donetti, E ^a   Cornaghi, L ^a   Gualerzi, A ^a   Baruffaldi Preis, F W ^b   Prignano, F ^c  

^a UNIVERSITY OF MILAN   (Italy)

^b IRCCS ISTITUTO ORTOPEDICO GALEAZZI   (Italy)

^c UNIVERSITY OF FLORENCE   (Italy)

Author keywords

Cell junctions; Keratin 10; Keratin 14; Keratinocyte proliferation; Psoriasis

Indexed keywords

CYTOKERATIN 10; CYTOKERATIN 14; EOSIN; HEMATOXYLIN; INTERLEUKIN 17; TUMOR NECROSIS FACTOR ALPHA; UVOMORULIN;

ADULT; ARTICLE; CELL ADHESION; CELL PROLIFERATION; CONTROLLED STUDY; DERMOEPIDERMAL JUNCTION; FEMALE; HUMAN; HUMAN TISSUE; IMMUNOFLUORESCENCE; KERATINOCYTE; MICROENVIRONMENT; NORMAL HUMAN; PRIORITY JOURNAL; PSORIASIS; QUANTITATIVE ANALYSIS; YOUNG ADULT; ANATOMY AND HISTOLOGY; AUDIOVISUAL EQUIPMENT; CYTOLOGY; FLUORESCENT ANTIBODY TECHNIQUE; PATHOLOGY; PATHOPHYSIOLOGY; PHYSIOLOGY; SKIN; TISSUE CULTURE TECHNIQUE;

ADULT; CELL ADHESION; CELL PROLIFERATION; FEMALE; FLUORESCENT ANTIBODY TECHNIQUE; HUMANS; INTERLEUKIN-17; MODELS, ANATOMIC; PSORIASIS; SKIN; TISSUE CULTURE TECHNIQUES; TUMOR NECROSIS FACTOR-ALPHA; YOUNG ADULT;

EID: 84897945122     PISSN: 10434666     EISSN: 10960023     Source Type: Journal    
DOI: 10.1016/j.cyto.2014.03.003     Document Type: Article

References (18)

1. Bonifati C., Ameglio F. Cytokine in psoriasis. Int J Dermatol 1999, 4:241-251.
2. Aggarwal B.B., Gupta S.C., Kim J.H. Historical perspectives on tumor necrosis factor and its superfamily: 25years later, a golden journey. Blood 2012, 119:651-665.
3. Mabuchi T., Chang T.W., Quinter S., Hwang S.T. Chemokine receptors in the pathogenesis and therapy of psoriasis. J Dermatol Sci 2012, 65:4-11.
4. Song X., Qian Y. The activation and regulation of IL-17 receptor mediated signaling. Cytokine 2013, 62:175-182.
5. Fitch E., Harper E., Skorcheva I., Kurtz S.E., Blauvelt A. Pathophysiology of psoriasis: recent advances on IL-23 and Th17 cytokines. Curr Rheumatol Rep 2007, 9:461-467.
6. vanRuissen F., deJongh G.J., vanErp E.J., Boezeman J.B.M., Schalkwijk J. Cell kinetic characterization of cultured human keratinocytes from normal and psoriatic individuals. J Cell Physiol 1996, 168:684-694.
7. Xia Y.P., Li B., Hylton D., Detmar M., Yancopoulos G.D., Rudge J.S. Transgenic delivery of VEGF to mouse skin leads to an inflammatory condition resembling human psoriasis. Blood 2003, 102:161-168.
8. Nestle F.O., Nickoloff B.J. From classical mouse models of psoriasis to a spontaneous xenograft model featuring use of AGR mice. Ernst Scher Res Found Workshop 2005, 203-212.
9. Mathers A.R., Janelsins B.M., Rubin J.P., Tkacheva O.A., Shufesky W.J., Watkins S.C., et al. Differential capability of human cutaneous dendritic cell subsets to initiate Th17 responses. J Immunol 2009, 182:921-933.
10. Bedoni M., Sforza C., Dolci C., Donetti E. Proliferation and differentiation biomarkers in normal human breast skin organotypic cultures. J Dermatol Sci 2007, 46:139-142.
11. Donetti E., Bedoni M., Boschini E., Bertelli A.A., Sforza C., Gagliano N. Early epidermal response after a single dose of gamma-rays in organotypic culture of human breast skin. Br J Dermatol 2005, 153:881-886.
12. Iizuka H., Takahashi H., Honma H., Ishida-Yamamoto A. Unique keratinization process in psoriasis: late differentiation markers are abolished because of the premature cell death. J Dermatol 2004, 31:271-276.
13. Fujiwara S., Nagai H., Oniki S., Yoshimoto T., Nishigori C. Interleukin (IL)-17 versus IL-27: opposite effects on tumor necrosis factor-α-mediated chemokine production in human keratinocytes. Exp Dermatol 2012, 21:70-82.
14. Kirschner N., Poetzl C., von den Driesch P., Wladykowski E., Moll I., Behne M.J., et al. Alteration of tight junction proteins is an early event in psoriasis: putative involvement of proinflammatory cytokines. Am J Pathol 2009, 175:1095-1106.
15. Gutowska-Owsiak D., Chan H.W., Schaupp A., Taylor S., Ogg G.S. IL-17 influences expression of genes associated with barrier function in keratinocytes. Br J Dermatol 2011, 164:104-110.
16. Donetti E., Gualerzi A., Bedoni M., Volpari T., Sciarabba M., Tartaglia G., et al. Desmoglein 3 and keratin 10 expressions are reduced by chronic exposure to cigarette smoke in human keratinised oral mucosa explants. Arch Oral Biol 2010, 55:815-823.
17. Parisi R., Symmons D.P., Griffiths C.E., Ashcroft D.M. Team IaMoPaACIp. J Invest Dermatol 2012, 133:377-385.
18. Reich K. The concept of psoriasis as a systemic inflammation: implications for disease management. J Eur Acad Dermatol Venereol 2012, 26:3-11.