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Volumn 119, Issue 3, 2012, Pages 651-665

Historical perspectives on tumor necrosis factor and its superfamily: 25 years later, a golden journey

Author keywords

[No Author keywords available]

Indexed keywords

B CELL ACTIVATING FACTOR RECEPTOR; CASPASE 3; CASPASE 9; CD27 ANTIGEN; CD30 ANTIGEN; CD40 LIGAND; FAS ANTIGEN; FAS ASSOCIATED DEATH DOMAIN PROTEIN; HLA DR3 ANTIGEN; I KAPPA B KINASE ALPHA; I KAPPA B KINASE BETA; LYMPHOTOXIN; OX40 LIGAND; RECEPTOR ACTIVATOR OF NUCLEAR FACTOR KAPPA B; TUMOR NECROSIS FACTOR; TUMOR NECROSIS FACTOR ALPHA; TUMOR NECROSIS FACTOR INHIBITOR; TUMOR NECROSIS FACTOR RECEPTOR ASSOCIATED DEATH DOMAIN PROTEIN; TUMOR NECROSIS FACTOR RECEPTOR ASSOCIATED FACTOR 1; TUMOR NECROSIS FACTOR RECEPTOR ASSOCIATED FACTOR 2; TUMOR NECROSIS FACTOR RECEPTOR ASSOCIATED FACTOR 3; TUMOR NECROSIS FACTOR RECEPTOR ASSOCIATED FACTOR 5; TUMOR NECROSIS FACTOR RELATED APOPTOSIS INDUCING LIGAND;

EID: 84862962823     PISSN: 00064971     EISSN: 15280020     Source Type: Journal    
DOI: 10.1182/blood-2011-04-325225     Document Type: Review
Times cited : (658)

References (144)
  • 1
    • 0041330433 scopus 로고    scopus 로고
    • Receptor-mediated choreography of life and death
    • DOI 10.1023/A:1025319031417
    • Bhardwaj A, Aggarwal BB. Receptor-mediated choreography of life and death. J Clin Immunol. 2003;23(5):317-332. (Pubitemid 37083187)
    • (2003) Journal of Clinical Immunology , vol.23 , Issue.5 , pp. 317-332
    • Bhardwaj, A.1    Aggarwal, B.B.2
  • 2
    • 0642283970 scopus 로고    scopus 로고
    • Regulation of proliferation, survival and apoptosis by members of the TNF superfamily
    • DOI 10.1016/S0006-2952(03)00490-8, PII S0006295203004908
    • Gaur U, Aggarwal BB. Regulation of proliferation, survival and apoptosis by members of the TNF superfamily. Biochem Pharmacol. 2003;66(8): 1403-1408. (Pubitemid 38373326)
    • (2003) Biochemical Pharmacology , vol.66 , Issue.8 , pp. 1403-1408
    • Gaur, U.1    Aggarwal, B.B.2
  • 3
    • 85047692516 scopus 로고    scopus 로고
    • Signalling pathways of the TNF superfamily: A double-edged sword
    • DOI 10.1038/nril184
    • Aggarwal BB. Signalling pathways of the TNF superfamily: a double-edged sword. Nat Rev Immunol. 2003;3(9):745-756. (Pubitemid 41070815)
    • (2003) Nature Reviews Immunology , vol.3 , Issue.9 , pp. 745-756
    • Aggarwal, B.B.1
  • 4
    • 0001206816 scopus 로고
    • Action of bacterial polysaccharide on tumors: II. Damage of Sarcoma 37 by serum of mice treated with Serratia marcescens polysaccharide, and induced tolerance
    • O'Malley. Action of bacterial polysaccharide on tumors: II. Damage of Sarcoma 37 by serum of mice treated with Serratia marcescens polysaccharide, and induced tolerance. J Natl Cancer Inst. 1962;29:1169-1175.
    • (1962) J Natl Cancer Inst , vol.29 , pp. 1169-1175
    • O'Malley1
  • 6
    • 0021344360 scopus 로고
    • Human lymphotoxin. Production by a lymphoblastoid cell line, purification, and initial characterization
    • Aggarwal BB, Moffat B, Harkins RN. Human lymphotoxin: production by a lymphoblastoid cell line, purification, and initial characterization. J Biol Chem. 1984;259(1):686-691. (Pubitemid 14177684)
    • (1984) Journal of Biological Chemistry , vol.259 , Issue.1 , pp. 686-691
    • Aggarwal, B.B.1    Moffat, B.2    Harkins, R.N.3
  • 7
    • 0021917069 scopus 로고
    • Primary structure of human lymphotoxin derived from 1788 lymphoblastoid cell line
    • Aggarwal BB, Henzel WJ, Moffat B, Kohr WJ, Harkins RN. Primary structure of human lymphotoxin derived from 1788 lymphoblastoid cell line. J Biol Chem. 1985;260(4):2334-2344. (Pubitemid 15104838)
    • (1985) Journal of Biological Chemistry , vol.260 , Issue.4 , pp. 2334-2344
    • Aggarwal, B.B.1    Henzel, W.J.2    Moffat, B.3
  • 8
    • 0021923645 scopus 로고
    • Human tumor necrosis factor: Production, purification, and characterization
    • Aggarwal BB, Kohr WJ, Hass PE, et al. Human tumor necrosis factor: production, purification, and characterization. J Biol Chem. 1985;260(4): 2345-2354. (Pubitemid 15104839)
    • (1985) Journal of Biological Chemistry , vol.260 , Issue.4 , pp. 2345-2354
    • Aggarwal, B.B.1    Kohr, W.J.2    Hass, P.E.3
  • 9
    • 0023639193 scopus 로고
    • Monoclonal antibodies to human tumor necrosis factors alpha and beta: application for affinity purification, immunoassays, and as structural probes
    • Bringman TS, Aggarwal BB. Monoclonal antibodies to human tumor necrosis factors alpha and beta: application for affinity purification, immunoassays, and as structural probes. Hybridoma. 1987;6(5):489-507. (Pubitemid 17168068)
    • (1987) Hybridoma , vol.6 , Issue.5 , pp. 489-507
    • Bringman, T.S.1    Aggarwal, B.B.2
  • 10
    • 0021866477 scopus 로고
    • Characterization of human tumor necrosis factor produced by peripheral blood monocytes and its separation from lymphotoxin
    • DOI 10.1002/ijc.2910360112
    • Kelker HC, Oppenheim JD, Stone-Wolff D, et al. Characterization of human tumor necrosis factor produced by peripheral blood monocytes and its separation from lymphotoxin. Int J Cancer. 1985; 36(1):69-73. (Pubitemid 15028617)
    • (1985) International Journal of Cancer , vol.36 , Issue.1 , pp. 69-73
    • Kelker, H.C.1    Oppenhaim, J.D.2    Stone-Wolff, D.3
  • 11
    • 0021681058 scopus 로고
    • Human tumour necrosis factor: Precursor structure, expression and homology to lymphotoxin
    • DOI 10.1038/312724a0
    • Pennica D, Nedwin GE, Hayflick JS, et al. Human tumour necrosis factor: precursor structure, expression and homology to lymphotoxin. Nature. 1984;312(5996):724-729. (Pubitemid 15195918)
    • (1984) Nature , vol.312 , Issue.5996 , pp. 724-729
    • Pennica, D.1    Nedwin, G.E.2    Hayflick, J.S.3
  • 12
    • 0021751122 scopus 로고
    • Cloning and expression of cDNA for human lymphotoxin, a lymphokine with tumour necrosis activity
    • DOI 10.1038/312721a0
    • Gray PW, Aggarwal BB, Benton CV, et al. Cloning and expression of cDNA for human lymphotoxin, a lymphokine with tumour necrosis activity. Nature. 1984;312(5996):721-724. (Pubitemid 15195917)
    • (1984) Nature , vol.312 , Issue.5996 , pp. 721-724
    • Gray, P.W.1    Aggarwal, B.B.2    Benton, C.V.3
  • 13
    • 0022377333 scopus 로고
    • Characterization of receptors for human tumour necrosis factor and their regulation by gamma-interferon
    • DOI 10.1038/318665a0
    • Aggarwal BB, Eessalu TE, Hass PE. Characterization of receptors for human tumour necrosis factor and their regulation by gamma-interferon. Nature. 1985;318(6047):665-667. (Pubitemid 16172416)
    • (1985) Nature , vol.318 , Issue.6047 , pp. 665-667
    • Aggarwal, B.B.1    Eessalu, T.E.2    Hass, P.E.3
  • 14
    • 0022371461 scopus 로고
    • Identity of tumour necrosis factor and the macrophage-secreted factor cachectin
    • DOI 10.1038/316552a0
    • Beutler B, Greenwald D, Hulmes JD, et al. Identity of tumour necrosis factor and the macrophage- secreted factor cachectin. Nature. 1985; 316(6028):552-554. (Pubitemid 16239366)
    • (1985) Nature , vol.316 , Issue.6028 , pp. 552-554
    • Beutler, B.1    Greenwald, D.2    Hulmes, J.D.3
  • 15
    • 78650185999 scopus 로고    scopus 로고
    • The value of failure: The discovery of TNF and its natural inhibitor erythropoietin
    • Cerami A. The value of failure: the discovery of TNF and its natural inhibitor erythropoietin. J Intern Med. 2011;269(1):8-15.
    • (2011) J Intern Med. , vol.269 , Issue.1 , pp. 8-15
    • Cerami, A.1
  • 18
    • 33845524008 scopus 로고    scopus 로고
    • TNF-alpha in promotion and progression of cancer
    • Balkwill F. TNF-alpha in promotion and progression of cancer. Cancer Metastasis Rev. 2006; 25(3):409-416.
    • (2006) Cancer Metastasis Rev. , vol.25 , Issue.3 , pp. 409-416
    • Balkwill, F.1
  • 19
    • 80054760660 scopus 로고    scopus 로고
    • Long-term results of tumor necrosis factor α- And melphalan-based isolated limb perfusion in locally advanced extremity soft tissue sarcomas
    • Deroose JP, Eggermont AM, van Geel AN, et al. Long-term results of tumor necrosis factor α- and melphalan-based isolated limb perfusion in locally advanced extremity soft tissue sarcomas. J Clin Oncol. 2011;29(30):4036-4044.
    • (2011) J Clin Oncol. , vol.29 , Issue.30 , pp. 4036-4044
    • Deroose, J.P.1    Eggermont, A.M.2    Van Geel, A.N.3
  • 20
    • 84856676019 scopus 로고    scopus 로고
    • 20 years experience of TNF-based isolated limb perfusion for in-transit melanoma metastases: TNF dose matters
    • published online ahead of print August 31, 2011 doi:10.1245/s10434-011- 2030-7
    • Deroose JP, Eggermont AM, van Geel AN, de Wilt JH, Burger JW, Verhoef C. 20 years experience of TNF-based isolated limb perfusion for in-transit melanoma metastases: TNF dose matters [published online ahead of print August 31, 2011]. Ann Surg Oncol. doi:10.1245/s10434-011-2030-7.
    • Ann Surg Oncol
    • Deroose, J.P.1    Eggermont, A.M.2    Van Geel, A.N.3    De Wilt, J.H.4    Burger, J.W.5    Verhoef, C.6
  • 21
    • 62249181618 scopus 로고    scopus 로고
    • Isolated limb perfusion with TNF-alpha and melphalan in locally advanced soft tissue sarcomas of the extremities
    • Grunhagen DJ, de Wilt JH, van Geel AN, Verhoef C, Eggermont AM. Isolated limb perfusion with TNF-alpha and melphalan in locally advanced soft tissue sarcomas of the extremities. Recent Results Cancer Res. 2009;179:257-270.
    • (2009) Recent Results Cancer Res. , vol.179 , pp. 257-270
    • Grunhagen, D.J.1    De Wilt, J.H.2    Van Geel, A.N.3    Verhoef, C.4    Eggermont, A.M.5
  • 22
    • 3042743700 scopus 로고    scopus 로고
    • Regulation of TRAIL-Induced Apoptosis by Ectopic Expression of Antiapoptotic Factors
    • DOI 10.1016/S0083-6729(04)67023-3, PII S0083672904670233, TRAIL (TNF-Related Apoptosis-Inducing Ligand)
    • Aggarwal BB, Bhardwaj U, Takada Y. Regulation of TRAIL-induced apoptosis by ectopic expression of antiapoptotic factors. Vitam Horm. 2004; 67:453-483. (Pubitemid 39753674)
    • (2004) Vitamins and Hormones , vol.67 , pp. 453-483
    • Aggarwal, B.B.1    Bhardwaj, U.2    Takada, Y.3
  • 23
    • 60549089207 scopus 로고    scopus 로고
    • APP binds DR6 to trigger axon pruning and neuron death via distinct caspases
    • Nikolaev A, McLaughlin T, O'Leary DD, Tessier-Lavigne M. APP binds DR6 to trigger axon pruning and neuron death via distinct caspases. Nature. 2009;457(7232):981-989.
    • (2009) Nature. , vol.457 , Issue.7232 , pp. 981-989
    • Nikolaev, A.1    McLaughlin, T.2    O'Leary, D.D.3    Tessier-Lavigne, M.4
  • 24
    • 0033560764 scopus 로고    scopus 로고
    • A casein kinase I motif present in the cytoplasmic domain of members of the tumour necrosis factor ligand family is implicated in 'reverse signalling'
    • .Watts AD, Hunt NH, Wanigasekara Y, et al. A casein kinase I motif present in the cytoplasmic domain of members of the tumour necrosis factor ligand family is implicated in "reverse signalling."EMBO J. 1999;18(8):2119-2126. (Pubitemid 29179169)
    • (1999) EMBO Journal , vol.18 , Issue.8 , pp. 2119-2126
    • Watts, A.D.1    Hunt, N.H.2    Wanigasekara, Y.3    Bloomfield, G.4    Wallach, D.5    Roufogalis, B.D.6    Chaudhri, G.7
  • 27
    • 0029007855 scopus 로고
    • The TNF receptor 1-associated protein TRADD signals cell death and NF-kappa B activation
    • Hsu H, Xiong J, Goeddel DV. The TNF receptor 1-associated protein TRADD signals cell death and NF-kappa B activation. Cell. 1995;81(4):495-504.
    • (1995) Cell , vol.81 , Issue.4 , pp. 495-504
    • Hsu, H.1    Xiong, J.2    Goeddel, D.V.3
  • 28
    • 0030032106 scopus 로고    scopus 로고
    • TRADD-TRAF2 and TRADD-FADD interactions define two distinct TNF receptor 1 signal transduction pathways
    • DOI 10.1016/S0092-8674(00)80984-8
    • Hsu H, Shu HB, Pan MG, Goeddel DV. TRADD-TRAF2 and TRADD-FADD interactions define two distinct TNF receptor 1 signal transduction pathways. Cell. 1996;84(2):299-308. (Pubitemid 26042835)
    • (1996) Cell , vol.84 , Issue.2 , pp. 299-308
    • Hsu, H.1    Shu, H.-B.2    Pan, M.-G.3    Goeddel, D.V.4
  • 29
    • 77955035878 scopus 로고    scopus 로고
    • Reactive oxygen species in TNFalpha-induced signaling and cell death
    • Morgan MJ, Liu ZG. Reactive oxygen species in TNFalpha-induced signaling and cell death. Mol Cells. 2010;30(1):1-12.
    • (2010) Mol Cells. , vol.30 , Issue.1 , pp. 1-12
    • Morgan, M.J.1    Liu, Z.G.2
  • 30
    • 4544342570 scopus 로고    scopus 로고
    • Nuclear factor-kappaB: The enemy within
    • Aggarwal BB. Nuclear factor-kappaB: the enemy within. Cancer Cell. 2004;6(3):203-208.
    • (2004) Cancer Cell. , vol.6 , Issue.3 , pp. 203-208
    • Aggarwal, B.B.1
  • 31
    • 0033725155 scopus 로고    scopus 로고
    • The distinct roles of TRAF2 and RIP in IKK activation by TNF-R1: TRAF2 recruits IKK to TNF-R1 while RIP mediates IKK activation
    • Devin A, Cook A, Lin Y, Rodriguez Y, Kelliher M, Liu Z. The distinct roles of TRAF2 and RIP in IKK activation by TNF-R1: TRAF2 recruits IKK to TNF-R1 while RIP mediates IKK activation. Immunity. 2000;12(4):419-429.
    • (2000) Immunity. , vol.12 , Issue.4 , pp. 419-429
    • Devin, A.1    Cook, A.2    Lin, Y.3    Rodriguez, Y.4    Kelliher, M.5    Liu, Z.6
  • 32
    • 0030666194 scopus 로고    scopus 로고
    • Tumor necrosis factor (TNF) receptor 1 signaling downstream of TNF receptor-associated factor 2. Nuclear factor kappaB (NFkappaB)-inducing kinase requirement for activation of activating protein 1 and NFkappaB but not of c- Jun N-terminal kinase/stress-activated protein kinase
    • DOI 10.1074/jbc.272.42.26079
    • Natoli G, Costanzo A, Moretti F, Fulco M, Balsano C, Levrero M. Tumor necrosis factor (TNF) receptor 1 signaling downstream of TNF receptor-associated factor 2: nuclear factor kappaB (NFkappaB)- inducing kinase requirement for activation of activating protein 1 and NFkappaB but not of c-Jun N-terminal kinase/stress-activated protein kinase. J Biol Chem. 1997;272(42):26079-26082. (Pubitemid 27458811)
    • (1997) Journal of Biological Chemistry , vol.272 , Issue.42 , pp. 26079-26082
    • Natoli, G.1    Costanzo, A.2    Moretti, F.3    Fulco, M.4    Balsano, C.5    Levrero, M.6
  • 33
    • 50049125047 scopus 로고    scopus 로고
    • Function of TRADD in tumor necrosis factor receptor 1 signaling and in TRIF-dependent inflammatory responses
    • Ermolaeva MA, Michallet MC, Papadopoulou N, et al. Function of TRADD in tumor necrosis factor receptor 1 signaling and in TRIF-dependent inflammatory responses. Nat Immunol. 2008;9(9): 1037-1046.
    • (2008) Nat Immunol. , vol.9 , Issue.9 , pp. 1037-1046
    • Ermolaeva, M.A.1    Michallet, M.C.2    Papadopoulou, N.3
  • 34
    • 0025299488 scopus 로고
    • Tumor necrosis factor-alpha exhibits greater proinflammatory activity than lymphotoxin in vitro
    • Desch CE, Dobrina A, Aggarwal BB, Harlan JM. Tumor necrosis factor-alpha exhibits greater proinflammatory activity than lymphotoxin in vitro. Blood. 1990;75(10):2030-2034. (Pubitemid 20180293)
    • (1990) Blood , vol.75 , Issue.10 , pp. 2030-2034
    • Desch, C.E.1    Dobrina, A.2    Aggarwal, B.B.3    Harlan, J.M.4
  • 35
    • 0022382737 scopus 로고
    • Recombinant human tumor necrosis factor-alpha: Effects on proliferation of normal and transformed cells in vitro
    • Sugarman BJ, Aggarwal BB, Hass PE, Figari IS, Palladino MA Jr, Shepard HM. Recombinant human tumor necrosis factor-alpha: effects on proliferation of normal and transformed cells in vitro. Science. 1985;230(4728):943-945. (Pubitemid 16193990)
    • (1985) Science , vol.230 , Issue.4728 , pp. 943-945
    • Sugarman, B.J.1    Aggarwal, B.B.2    Hass, P.E.3
  • 36
    • 67349162130 scopus 로고    scopus 로고
    • Tumour necrosis factor and cancer
    • Balkwill F. Tumour necrosis factor and cancer. Nat Rev Cancer. 2009;9(5):361-371.
    • (2009) Nat Rev Cancer , vol.9 , Issue.5 , pp. 361-371
    • Balkwill, F.1
  • 37
    • 33750497844 scopus 로고    scopus 로고
    • Inflammation and cancer: How hot is the link?
    • DOI 10.1016/j.bcp.2006.06.029, PII S0006295206003893, Cell Signalling, Transcription and Translation as Therapeutic Tergets
    • Aggarwal BB, Shishodia S, Sandur SK, Pandey MK, Sethi G. Inflammation and cancer: how hot is the link? Biochem Pharmacol. 2006;72(11):1605-1621. (Pubitemid 44666739)
    • (2006) Biochemical Pharmacology , vol.72 , Issue.11 , pp. 1605-1621
    • Aggarwal, B.B.1    Shishodia, S.2    Sandur, S.K.3    Pandey, M.K.4    Sethi, G.5
  • 39
    • 75849155537 scopus 로고    scopus 로고
    • A meta-analysis of cytokines in major depression
    • Dowlati Y, Herrmann N, Swardfager W, et al. A meta-analysis of cytokines in major depression. Biol Psychiatry. 2010;67(5):446-457.
    • (2010) Biol Psychiatry. , vol.67 , Issue.5 , pp. 446-457
    • Dowlati, Y.1    Herrmann, N.2    Swardfager, W.3
  • 41
    • 77953433252 scopus 로고    scopus 로고
    • Role of cytokines during epileptogenesis and in the transition from the interictal to the ictal state in the epileptic mutant EL mouse
    • Murashima YL, Suzuki J, Yoshii M. Role of cytokines during epileptogenesis and in the transition from the interictal to the ictal state in the epileptic mutant EL mouse. Gene Regul Syst Bio. 2008;2: 267-274.
    • (2008) Gene Regul Syst Bio , vol.2 , pp. 267-274
    • Murashima, Y.L.1    Suzuki, J.2    Yoshii, M.3
  • 43
    • 14744296610 scopus 로고    scopus 로고
    • Inflammatory process in Parkinson's disease: Role for cytokines
    • DOI 10.2174/1381612053381620
    • Nagatsu T, Sawada M. Inflammatory process in Parkinson's disease: role for cytokines. Curr Pharm Des. 2005;11(8):999-1016. (Pubitemid 40331301)
    • (2005) Current Pharmaceutical Design , vol.11 , Issue.8 , pp. 999-1016
    • Nagatsu, T.1    Sawada, M.2
  • 44
    • 77953639372 scopus 로고    scopus 로고
    • Meningeal mast cells affect early T cell central nervous system infiltration and blood-brain barrier integrity through TNF: A role for neutrophil recruitment?
    • Sayed BA, Christy AL, Walker ME, Brown MA. Meningeal mast cells affect early T cell central nervous system infiltration and blood-brain barrier integrity through TNF: a role for neutrophil recruitment? J Immunol. 2010;184(12):6891-6900.
    • (2010) J Immunol. , vol.184 , Issue.12 , pp. 6891-6900
    • Sayed, B.A.1    Christy, A.L.2    Walker, M.E.3    Brown, M.A.4
  • 45
    • 0036201312 scopus 로고    scopus 로고
    • Fas engagement increases expression of interleukin-6 in human glioma cells
    • DOI 10.1023/A:1014467626314
    • Choi C, Gillespie GY, Van Wagoner NJ, Benveniste EN. Fas engagement increases expression of interleukin-6 in human glioma cells. J Neuro-oncol. 2002;56(1):13-19. (Pubitemid 34256613)
    • (2002) Journal of Neuro-Oncology , vol.56 , Issue.1 , pp. 13-19
    • Choi, C.1    Gillespie, G.Y.2    Van Wagoner, N.J.3    Benveniste, E.N.4
  • 46
    • 0028982826 scopus 로고
    • Tumor necrosis factor-alpha gene and protein expression in adult feline myocardium after endotoxin administration
    • Kapadia S, Lee J, Torre-Amione G, Birdsall HH, Ma TS, Mann DL. Tumor necrosis factor-alpha gene and protein expression in adult feline myocardium after endotoxin administration. J Clin Invest. 1995;96(2):1042-1052.
    • (1995) J Clin Invest. , vol.96 , Issue.2 , pp. 1042-1052
    • Kapadia, S.1    Lee, J.2    Torre-Amione, G.3    Birdsall, H.H.4    Ma, T.S.5    Mann, D.L.6
  • 47
    • 0025286817 scopus 로고
    • Elevated circulating levels of tumor necrosis factor in severe chronic heart failure
    • Levine B, Kalman J, Mayer L, Fillit HM, Packer M. Elevated circulating levels of tumor necrosis factor in severe chronic heart failure. N Engl J Med. 1990;323(4):236-241. (Pubitemid 20225044)
    • (1990) New England Journal of Medicine , vol.323 , Issue.4 , pp. 236-241
    • Levine, B.1    Kalman, J.2    Mayer, L.3    Fillit, H.M.4    Packer, M.5
  • 49
    • 0037333873 scopus 로고    scopus 로고
    • Inflammatory mediators and the failing heart: A translational approach
    • DOI 10.2174/1566524033361537
    • Diwan A, Tran T, Misra A, Mann DL. Inflammatory mediators and the failing heart: a translational approach. Curr Mol Med. 2003;3(2):161-182. (Pubitemid 36285104)
    • (2003) Current Molecular Medicine , vol.3 , Issue.2 , pp. 161-182
    • Diwan, A.1    Tran, T.2    Misra, A.3    Mann, D.L.4
  • 50
    • 69249222895 scopus 로고    scopus 로고
    • Role for TNF in atherosclerosis? Lessons from autoimmune disease
    • McKellar GE, McCarey DW, Sattar N, McInnes IB. Role for TNF in atherosclerosis? Lessons from autoimmune disease. Nat Rev Cardiol. 2009;6(6):410-417.
    • (2009) Nat Rev Cardiol , vol.6 , Issue.6 , pp. 410-417
    • McKellar, G.E.1    McCarey, D.W.2    Sattar, N.3    McInnes, I.B.4
  • 51
    • 57149096904 scopus 로고    scopus 로고
    • Risk of cardiovascular mortality in patients with rheumatoid arthritis: A meta-analysis of observational studies
    • Avina-Zubieta JA, Choi HK, Sadatsafavi M, Etminan M, Esdaile JM, Lacaille D. Risk of cardiovascular mortality in patients with rheumatoid arthritis: a meta-analysis of observational studies. Arthritis Rheum. 2008;59(12):1690-1697.
    • (2008) Arthritis Rheum. , vol.59 , Issue.12 , pp. 1690-1697
    • Avina-Zubieta, J.A.1    Choi, H.K.2    Sadatsafavi, M.3    Etminan, M.4    Esdaile, J.M.5    Lacaille, D.6
  • 52
    • 75749095929 scopus 로고    scopus 로고
    • TNF-alpha inhibitors in asthma and COPD: We must not throw the baby out with the bath water
    • Matera MG, Calzetta L, Cazzola M. TNF-alpha inhibitors in asthma and COPD: we must not throw the baby out with the bath water. Pulm Pharmacol Ther. 2010;23(2):121-128.
    • (2010) Pulm Pharmacol Ther. , vol.23 , Issue.2 , pp. 121-128
    • Matera, M.G.1    Calzetta, L.2    Cazzola, M.3
  • 55
    • 70449491806 scopus 로고    scopus 로고
    • Emerging role of tumour necrosis factor-related apoptosis-inducing ligand (TRAIL) as a key regulator of inflammatory responses
    • Collison A, Foster PS, Mattes J. Emerging role of tumour necrosis factor-related apoptosis-inducing ligand (TRAIL) as a key regulator of inflammatory responses. Clin Exp Pharmacol Physiol. 2009; 36(11):1049-1053.
    • (2009) Clin Exp Pharmacol Physiol. , vol.36 , Issue.11 , pp. 1049-1053
    • Collison, A.1    Foster, P.S.2    Mattes, J.3
  • 56
    • 77957828102 scopus 로고    scopus 로고
    • Therapeutic Treg expansion in mice by TNFRSF25 prevents allergic lung inflammation
    • Schreiber TH, Wolf D, Tsai MS, et al. Therapeutic Treg expansion in mice by TNFRSF25 prevents allergic lung inflammation. J Clin Invest. 2010; 120(10):3629-3640.
    • (2010) J Clin Invest. , vol.120 , Issue.10 , pp. 3629-3640
    • Schreiber, T.H.1    Wolf, D.2    Tsai, M.S.3
  • 57
    • 0027459878 scopus 로고
    • Adipose expression of tumor necrosis factor-alpha: Direct role in obesity-linked insulin resistance
    • Hotamisligil GS, Shargill NS, Spiegelman BM. Adipose expression of tumor necrosis factor-alpha: direct role in obesity-linked insulin resistance. Science. 1993;259(5091):87-91. (Pubitemid 23036092)
    • (1993) Science , vol.259 , Issue.5091 , pp. 87-91
    • Hotamisligil, G.S.1    Shargill, N.S.2    Spiegelman, B.M.3
  • 59
    • 0348222671 scopus 로고    scopus 로고
    • Inflammation: The link between insulin resistance, obesity and diabetes
    • DOI 10.1016/j.it.2003.10.013
    • Dandona P, Aljada A, Bandyopadhyay A. Inflammation: the link between insulin resistance, obesity and diabetes. Trends Immunol. 2004;25(1): 4-7. (Pubitemid 38032801)
    • (2004) Trends in Immunology , vol.25 , Issue.1 , pp. 4-7
    • Dandona, P.1    Aljada, A.2    Bandyopadhyay, A.3
  • 60
    • 79953770639 scopus 로고    scopus 로고
    • The tumour necrosis factor/ TNF receptor superfamily: Therapeutic targets in autoimmune diseases
    • Vinay DS, Kwon BS. The tumour necrosis factor/ TNF receptor superfamily: therapeutic targets in autoimmune diseases. Clin Exp Immunol. 2011; 164:145-157.
    • (2011) Clin Exp Immunol. , vol.164 , pp. 145-157
    • Vinay, D.S.1    Kwon, B.S.2
  • 61
    • 0028979065 scopus 로고
    • Lymphotoxin- Alpha-deficient mice: Effects on secondary lymphoid organ development and humoral immune responsiveness
    • Banks TA, Rouse BT, Kerley MK, et al. Lymphotoxin- alpha-deficient mice: effects on secondary lymphoid organ development and humoral immune responsiveness. J Immunol. 1995;155(4): 1685-1693.
    • (1995) J Immunol. , vol.155 , Issue.4 , pp. 1685-1693
    • Banks, T.A.1    Rouse, B.T.2    Kerley, M.K.3
  • 62
    • 0029989339 scopus 로고    scopus 로고
    • Immune and inflammatory responses in TNF alpha-deficient mice: A critical requirement for TNFalpha in the formation of primary B cell follicles, follicular dendritic cell networks and germinal centers, and in the maturation of the humoral immune response
    • DOI 10.1084/jem.184.4.1397
    • Pasparakis M, Alexopoulou L, Episkopou V, Kollias G. Immune and inflammatory responses in TNF alpha-deficient mice: a critical requirement for TNF alpha in the formation of primary B cell follicles, follicular dendritic cell networks and germinal centers, and in the maturation of the humoral immune response. J Exp Med. 1996; 184(4):1397-1411. (Pubitemid 26354696)
    • (1996) Journal of Experimental Medicine , vol.184 , Issue.4 , pp. 1397-1411
    • Pasparakis, M.1    Alexopoulou, L.2    Episkopou, V.3    Kollias, G.4
  • 64
    • 73549121069 scopus 로고    scopus 로고
    • TRAIL-deficient mice exhibit delayed regression of retinal neovascularization
    • Hubert KE, Davies MH, Stempel AJ, Griffith TS, Powers MR. TRAIL-deficient mice exhibit delayed regression of retinal neovascularization. Am J Pathol. 2009;175(6):2697-2708.
    • (2009) Am J Pathol. , vol.175 , Issue.6 , pp. 2697-2708
    • Hubert, K.E.1    Davies, M.H.2    Stempel, A.J.3    Griffith, T.S.4    Powers, M.R.5
  • 67
    • 5444276447 scopus 로고    scopus 로고
    • A novel mutation (T61I) in the gene encoding tumour necrosis factor receptor superfamily 1A (TNFRSF1A) in a Japanese patient with tumour necrosis factor receptor-associated periodic syndrome (TRAPS) associated with systemic lupus erythematosus
    • DOI 10.1093/rheumatology/keh320
    • Ida H, Kawasaki E, Miyashita T, et al. A novel mutation (T61I) in the gene encoding tumour necrosis factor receptor superfamily 1A (TNFRSF1A) in a Japanese patient with tumour necrosis factor receptor-associated periodic syndrome (TRAPS) associated with systemic lupus erythematosus. Rheumatology (Oxford). 2004;43(10):1292-1299. (Pubitemid 39359307)
    • (2004) Rheumatology , vol.43 , Issue.10 , pp. 1292-1299
    • Ida, H.1    Kawasaki, E.2    Miyashita, T.3    Tanaka, F.4    Kamachi, M.5    Izumi, Y.6    Huang, M.7    Tamai, M.8    Origuchi, T.9    Kawakami, A.10    Migita, K.11    Motomura, M.12    Yoshimura, T.13    Eguchi, K.14
  • 68
    • 0242552818 scopus 로고    scopus 로고
    • TNF-alpha and TNF-beta gene polymorphisms in cerebral infarction
    • Um JY, An NH, Kim HM. TNF-alpha and TNF-beta gene polymorphisms in cerebral infarction. J Mol Neurosci. 2003;21(2):167-171.
    • (2003) J Mol Neurosci. , vol.21 , Issue.2 , pp. 167-171
    • Um, J.Y.1    An, N.H.2    Kim, H.M.3
  • 69
    • 78650589350 scopus 로고    scopus 로고
    • Golimumab: Review of the efficacy and tolerability of a recently approved tumor necrosis factor-alpha inhibitor
    • Boyce EG, Halilovic J, Stan-Ugbene O. Golimumab: review of the efficacy and tolerability of a recently approved tumor necrosis factor-alpha inhibitor. Clin Ther. 2010;32(10):1681-1703.
    • (2010) Clin Ther. , vol.32 , Issue.10 , pp. 1681-1703
    • Boyce, E.G.1    Halilovic, J.2    Stan-Ugbene, O.3
  • 71
    • 77954950402 scopus 로고    scopus 로고
    • Atacicept: Targeting B cells in multiple sclerosis
    • Hartung HP, Kieseier BC. Atacicept: targeting B cells in multiple sclerosis. Ther Adv Neurol Disord. 2010;3(4):205-216.
    • (2010) Ther Adv Neurol Disord , vol.3 , Issue.4 , pp. 205-216
    • Hartung, H.P.1    Kieseier, B.C.2
  • 72
    • 79959832697 scopus 로고    scopus 로고
    • Atacicept in patients with rheumatoid arthritis and an inadequate response to tumor necrosis factor antagonist therapy: Results of a phase II, randomized, placebo-controlled, dose-finding trial
    • Genovese MC, Kinnman N, de La Bourdonnaye G, Pena Rossi C, Tak PP. Atacicept in patients with rheumatoid arthritis and an inadequate response to tumor necrosis factor antagonist therapy: results of a phase II, randomized, placebo-controlled, dose-finding trial. Arthritis Rheum. 2011;63(7):1793-1803.
    • (2011) Arthritis Rheum. , vol.63 , Issue.7 , pp. 1793-1803
    • Genovese, M.C.1    Kinnman, N.2    De La Bourdonnaye, G.3    Pena Rossi, C.4    Tak, P.P.5
  • 73
    • 79959856423 scopus 로고    scopus 로고
    • Atacicept in patients with rheumatoid arthritis and an inadequate response to methotrexate: Results of a phase II, randomized, placebo- Controlled trial
    • van Vollenhoven RF, Kinnman N, Vincent E, Wax S, Bathon J. Atacicept in patients with rheumatoid arthritis and an inadequate response to methotrexate: results of a phase II, randomized, placebo- controlled trial. Arthritis Rheum. 2011;63(7): 1782-1792.
    • (2011) Arthritis Rheum. , vol.63 , Issue.7 , pp. 1782-1792
    • Van Vollenhoven, R.F.1    Kinnman, N.2    Vincent, E.3    Wax, S.4    Bathon, J.5
  • 74
    • 0028867742 scopus 로고
    • Activation of transcription factor NF-kappa B is suppressed by curcumin (diferuloylmethane)
    • corrected
    • Singh S, Aggarwal BB. Activation of transcription factor NF-kappa B is suppressed by curcumin (diferuloylmethane) [corrected]. J Biol Chem. 1995;270(42):24995-25000.
    • (1995) J Biol Chem , vol.270 , Issue.42 , pp. 24995-25000
    • Singh, S.1    Aggarwal, B.B.2
  • 75
    • 0029047933 scopus 로고
    • Inhibition of tumor necrosis factor by curcumin, a phytochemical
    • Chan MM. Inhibition of tumor necrosis factor by curcumin, a phytochemical. Biochem Pharmacol. 1995;49(11):1551-1556.
    • (1995) Biochem Pharmacol. , vol.49 , Issue.11 , pp. 1551-1556
    • Chan, M.M.1
  • 76
    • 81355142057 scopus 로고    scopus 로고
    • Multitargeting by curcumin as revealed by molecular interaction studies
    • Gupta SC, Prasad S, Kim JH, et al. Multitargeting by curcumin as revealed by molecular interaction studies Nat Prod Rep. 2011;28(12):1937-1955.
    • (2011) Nat Prod Rep. , vol.28 , Issue.12 , pp. 1937-1955
    • Gupta, S.C.1    Prasad, S.2    Kim, J.H.3
  • 77
    • 81355129834 scopus 로고    scopus 로고
    • Docking prediction for tumor necrosis factor-α and five herbal inhibitors
    • .Wua ST, Suna JC, Leeb KJ, Sunc YM. Docking prediction for tumor necrosis factor-α and five herbal inhibitors. Intl J Eng Sci Technol. 2010;2: 4263-4277.
    • (2010) Intl J Eng Sci Technol , vol.2 , pp. 4263-4277
    • Wua, S.T.1    Suna, J.C.2    Leeb, K.J.3    Sunc, Y.M.4
  • 78
    • 42649124339 scopus 로고    scopus 로고
    • TNF: A master switch for inflammation to cancer
    • DOI 10.2741/3066
    • Sethi G, Sung B, Aggarwal BB. TNF: a master switch for inflammation to cancer. Front Biosci. 2008;13:5094-5107. (Pubitemid 351599660)
    • (2008) Frontiers in Bioscience , vol.13 , Issue.13 , pp. 5094-5107
    • Sethi, G.1    Sung, B.2    Aggarwal, B.B.3
  • 79
    • 12644272789 scopus 로고    scopus 로고
    • Tumor necrosis factor (TNF)-mediated kinase cascades: Bifurcation of nuclear factor-kappaB and c-jun N-terminal kinase (JNK/SAPK) pathways at TNF receptor-associated factor 2
    • DOI 10.1073/pnas.94.18.9792
    • Song HY, Regnier CH, Kirschning CJ, Goeddel DV, Rothe M. Tumor necrosis factor (TNF)-mediated kinase cascades: bifurcation of nuclear factor-kappaB and c-jun N-terminal kinase (JNK/SAPK) pathways at TNF receptor-associated factor 2. Proc Natl Acad Sci U S A. 1997;94(18): 9792-9796. (Pubitemid 27408143)
    • (1997) Proceedings of the National Academy of Sciences of the United States of America , vol.94 , Issue.18 , pp. 9792-9796
    • Song, H.Y.1    Regnier, C.H.2    Kirschning, C.J.3    Goeddel, D.V.4    Rothe, M.5
  • 80
    • 0032575591 scopus 로고    scopus 로고
    • 2-terminal kinase (JNK) and p38. Germinal center kinase couples TRAF2 to mitogen-activated protein kinase/ERK kinase kinase 1 and SAPK while receptor interacting protein associates with a mitogen-activated protein kinase kinase kinase upstream of MKK6 and p38
    • DOI 10.1074/jbc.273.35.22681
    • Yuasa T, Ohno S, Kehrl JH, Kyriakis JM. Tumor necrosis factor signaling to stress-activated protein kinase (SAPK)/Jun NH2-terminal kinase (JNK) and p38: germinal center kinase couples TRAF2 to mitogen-activated protein kinase/ERK kinase kinase 1 and SAPK while receptor interacting protein associates with a mitogen-activated protein kinase kinase kinase upstream of MKK6 and p38. J Biol Chem. 1998;273(35): 22681-22692. (Pubitemid 28399839)
    • (1998) Journal of Biological Chemistry , vol.273 , Issue.35 , pp. 22681-22692
    • Yuasa, T.1    Ohno, S.2    Kehrl, J.H.3    Kyriakis, J.M.4
  • 81
    • 0030741389 scopus 로고    scopus 로고
    • Abnormal development of secondary lymphoid tissues in lymphotoxin beta-deficient mice
    • Alimzhanov MB, Kuprash DV, Kosco-Vilbois MH, et al. Abnormal development of secondary lymphoid tissues in lymphotoxin beta-deficient mice. Proc Natl Acad Sci U S A. 1997;94(17):9302-9307.
    • (1997) Proc Natl Acad Sci U S A. , vol.94 , Issue.17 , pp. 9302-9307
    • Alimzhanov, M.B.1    Kuprash, D.V.2    Kosco-Vilbois, M.H.3
  • 82
    • 0035936797 scopus 로고    scopus 로고
    • The TNF and TNF receptor superfamilies: Integrating mammalian biology
    • DOI 10.1016/S0092-8674(01)00237-9
    • Locksley RM, Killeen N, Lenardo MJ. The TNF and TNF receptor superfamilies: integrating mammalian biology. Cell. 2001;104(4):487-501. (Pubitemid 32201945)
    • (2001) Cell , vol.104 , Issue.4 , pp. 487-501
    • Locksley, R.M.1    Killeen, N.2    Lenardo, M.J.3
  • 83
    • 0034718609 scopus 로고    scopus 로고
    • Diverse roles of the tumor necrosis factor family member TRANCE in skeletal physiology revealed by TRANCE deficiency and partial rescue by a lymphocyte-expressed TRANCE transgene
    • Kim N, Odgren PR, Kim DK, Marks SC Jr, Choi Y. Diverse roles of the tumor necrosis factor family member TRANCE in skeletal physiology revealed by TRANCE deficiency and partial rescue by a lymphocyte-expressed TRANCE transgene. Proc Natl Acad Sci U S A. 2000;97(20):10905-10910.
    • (2000) Proc Natl Acad Sci U S A. , vol.97 , Issue.20 , pp. 10905-10910
    • Kim, N.1    Odgren, P.R.2    Kim, D.K.3    Marks Jr., S.C.4    Choi, Y.5
  • 88
    • 0032231350 scopus 로고    scopus 로고
    • Identification of a new splice form of the EDA1 gene permits detection of nearly all X-linked hypohidrotic ectodermal dysplasia mutations
    • DOI 10.1086/301984
    • Monreal AW, Zonana J, Ferguson B. Identification of a new splice form of the EDA1 gene permits detection of nearly all X-linked hypohidrotic ectodermal dysplasia mutations. Am J Hum Genet. 1998;63(2):380-389. (Pubitemid 30418619)
    • (1998) American Journal of Human Genetics , vol.63 , Issue.2 , pp. 380-389
    • Monreal, A.W.1    Zonana, J.2    Ferguson, B.3
  • 89
    • 0035379554 scopus 로고    scopus 로고
    • Mutations leading to X-linked hypohidrotic ectodermal dysplasia affect three major functional domains in the tumor necrosis factor family member ectodysplasin-A
    • Schneider P, Street SL, Gaide O, et al. Mutations leading to X-linked hypohidrotic ectodermal dysplasia affect three major functional domains in the tumor necrosis factor family member ectodysplasin-A. J Biol Chem. 2001;276(22):18819-18827.
    • (2001) J Biol Chem. , vol.276 , Issue.22 , pp. 18819-18827
    • Schneider, P.1    Street, S.L.2    Gaide, O.3
  • 90
    • 0842282549 scopus 로고    scopus 로고
    • Myodegeneration in EDA-A2 Transgenic Mice Is Prevented by XEDAR Deficiency
    • DOI 10.1128/MCB.24.4.1608-1613.2004
    • Newton K, French DM, Yan M, Frantz GD, Dixit VM. Myodegeneration in EDA-A2 transgenic mice is prevented by XEDAR deficiency. Mol Cell Biol. 2004;24(4):1608-1613. (Pubitemid 38167082)
    • (2004) Molecular and Cellular Biology , vol.24 , Issue.4 , pp. 1608-1613
    • Newton, K.1    French, D.M.2    Yan, M.3    Frantz, G.D.4    Dixit, V.M.5
  • 93
    • 0029006893 scopus 로고
    • Mutations in Fas associated with human lymphoproliferative syndrome and autoimmunity
    • Rieux-Laucat F, Le Deist F, Hivroz C, et al. Mutations in Fas associated with human lymphoproliferative syndrome and autoimmunity. Science. 1995;268(5215):1347-1349.
    • (1995) Science. , vol.268 , Issue.5215 , pp. 1347-1349
    • Rieux-Laucat, F.1    Le Deist, F.2    Hivroz, C.3
  • 94
    • 0028789148 scopus 로고
    • Anatomy of autoantibody production: Dominant localization of antibody-producing cells to T cell zones in Fasdeficient mice
    • Jacobson BA, Panka DJ, Nguyen KA, Erikson J, Abbas AK, Marshak-Rothstein A. Anatomy of autoantibody production: dominant localization of antibody-producing cells to T cell zones in Fasdeficient mice. Immunity. 1995;3(4):509-519.
    • (1995) Immunity , vol.3 , Issue.4 , pp. 509-519
    • Jacobson, B.A.1    Panka, D.J.2    Nguyen, K.A.3    Erikson, J.4    Abbas, A.K.5    Marshak-Rothstein, A.6
  • 95
    • 0028485743 scopus 로고
    • The fas antigen is involved in peripheral but not thymic deletion of T lymphocytes in T cell receptor transgenic mice
    • Singer GG, Abbas AK. The fas antigen is involved in peripheral but not thymic deletion of T lymphocytes in T cell receptor transgenic mice. Immunity. 1994;1(5):365-371.
    • (1994) Immunity , vol.1 , Issue.5 , pp. 365-371
    • Singer, G.G.1    Abbas, A.K.2
  • 96
    • 15444378040 scopus 로고    scopus 로고
    • Mice deficient in OX40 and CD30 signals lack memory antibody responses because of deficient CD4 T cell memory
    • Gaspal FM, Kim MY, McConnell FM, Raykundalia C, Bekiaris V, Lane PJ. Mice deficient in OX40 and CD30 signals lack memory antibody responses because of deficient CD4 T cell memory. J Immunol. 2005;174(7):3891-3896. (Pubitemid 40395961)
    • (2005) Journal of Immunology , vol.174 , Issue.7 , pp. 3891-3896
    • Gaspal, F.M.C.1    Kim, M.-Y.2    McConnell, F.M.3    Raykundalia, C.4    Bekiaris, V.5    Lane, P.J.L.6
  • 98
    • 4644245852 scopus 로고    scopus 로고
    • CD137-deficient mice have reduced NK/NKT cell numbers and function, are resistant to lipopolysaccharide-induced shock syndromes, and have lower IL-4 responses
    • Vinay DS, Choi BK, Bae JS, Kim WY, Gebhardt BM, Kwon BS. CD137-deficient mice have reduced NK/NKT cell numbers and function, are resistant to lipopolysaccharide-induced shock syndromes, and have lower IL-4 responses. J Immunol. 2004;173(6):4218-4229. (Pubitemid 39280788)
    • (2004) Journal of Immunology , vol.173 , Issue.6 , pp. 4218-4229
    • Vinay, D.S.1    Choi, B.K.2    Bae, J.S.3    Kim, W.Y.4    Gebhardt, B.M.5    Kwon, B.S.6
  • 99
    • 47849100724 scopus 로고    scopus 로고
    • Identification of regulatory functions for 4-1BB and 4-1BBL in myelopoiesis and the development of dendritic cells
    • Lee SW, Park Y, So T, et al. Identification of regulatory functions for 4-1BB and 4-1BBL in myelopoiesis and the development of dendritic cells. Nat Immunol. 2008;9(8):917-926.
    • (2008) Nat Immunol. , vol.9 , Issue.8 , pp. 917-926
    • Lee, S.W.1    Park, Y.2    So, T.3
  • 100
    • 77949352851 scopus 로고    scopus 로고
    • CD137 (4-1BB) deficiency reduces atherosclerosis in hyperlipidemic mice
    • Jeon HJ, Choi JH, Jung IH, et al. CD137 (4-1BB) deficiency reduces atherosclerosis in hyperlipidemic mice. Circulation. 2010;121(9):1124-1133.
    • (2010) Circulation. , vol.121 , Issue.9 , pp. 1124-1133
    • Jeon, H.J.1    Choi, J.H.2    Jung, I.H.3
  • 103
    • 77954227963 scopus 로고    scopus 로고
    • Tumor necrosis factor-like weak inducer of apoptosis is a mitogen for liver progenitor cells
    • Tirnitz-Parker JE, Viebahn CS, Jakubowski A, et al. Tumor necrosis factor-like weak inducer of apoptosis is a mitogen for liver progenitor cells. Hepatology. 2010;52(1):291-302.
    • (2010) Hepatology. , vol.52 , Issue.1 , pp. 291-302
    • Tirnitz-Parker, J.E.1    Viebahn, C.S.2    Jakubowski, A.3
  • 105
    • 0035797908 scopus 로고    scopus 로고
    • Identification of a novel receptor for B lymphocyte stimulator that is mutated in a mouse strain with severe B cell deficiency
    • DOI 10.1016/S0960-9822(01)00481-X
    • Yan M, Brady JR, Chan B, et al. Identification of a novel receptor for B lymphocyte stimulator that is mutated in a mouse strain with severe B cell deficiency. Curr Biol. 2001;11(19):1547-1552. (Pubitemid 32931019)
    • (2001) Current Biology , vol.11 , Issue.19 , pp. 1547-1552
    • Yan, M.1    Brady, J.R.2    Chan, B.3    Lee, W.P.4    Hsu, B.5    Harless, S.6    Cancro, M.7    Grewal, I.S.8    Dixit, V.M.9
  • 108
    • 54449097840 scopus 로고    scopus 로고
    • Edar and Troy signalling pathways act redundantly to regulate initiation of hair follicle development
    • Pispa J, Pummila M, Barker PA, Thesleff I, Mikkola ML. Edar and Troy signalling pathways act redundantly to regulate initiation of hair follicle development. Hum Mol Genet. 2008;17(21): 3380-3391.
    • (2008) Hum Mol Genet , vol.17 , Issue.21 , pp. 3380-3391
    • Pispa, J.1    Pummila, M.2    Barker, P.A.3    Thesleff, I.4    Mikkola, M.L.5
  • 110
    • 0035914945 scopus 로고    scopus 로고
    • Impaired c-Jun amino terminal kinase activity and T cell differentiation in death receptor 6-deficient mice
    • DOI 10.1084/jem.194.10.1441
    • Zhao H, Yan M, Wang H, Erickson S, Grewal IS, Dixit VM. Impaired c-Jun amino terminal kinase activity and T cell differentiation in death receptor 6-deficient mice. J Exp Med. 2001;194(10):1441-1448. (Pubitemid 33081519)
    • (2001) Journal of Experimental Medicine , vol.194 , Issue.10 , pp. 1441-1448
    • Zhao, H.1    Yan, M.2    Wang, H.3    Erickson, S.4    Grewal, I.S.5    Dixit, V.M.6
  • 111
    • 0034903664 scopus 로고    scopus 로고
    • + T cell proliferation and Th2 cytokine production in DR6-deficient mice
    • DOI 10.1016/S1074-7613(01)00162-5, PII S1074761301001625
    • Liu J, Na S, Glasebrook A, et al. Enhanced CD4+T cell proliferation and Th2 cytokine production in DR6-deficient mice. Immunity. 2001;15(1):23-34. (Pubitemid 32728317)
    • (2001) Immunity , vol.15 , Issue.1 , pp. 23-34
    • Liu, J.1    Na, S.2    Glasebrook, A.3    Fox, N.4    Solenberg, P.J.5    Zhang, Q.6    Song, H.Y.7    Yang, D.D.8
  • 112
    • 0026747063 scopus 로고
    • Targeted mutation of the gene encoding the low affinity NGF receptor p75 leads to deficits in the peripheral sensory nervous system
    • Lee KF, Li E, Huber LJ, et al. Targeted mutation of the gene encoding the low affinity NGF receptor p75 leads to deficits in the peripheral sensory nervous system. Cell. 1992;69(5):737-749.
    • (1992) Cell. , vol.69 , Issue.5 , pp. 737-749
    • Lee, K.F.1    Li, E.2    Huber, L.J.3
  • 113
    • 0034752285 scopus 로고    scopus 로고
    • TRAF1 is a negative regulator of TNF signaling: Enhanced TNF signaling in TRAF1-deficient mice
    • DOI 10.1016/S1074-7613(01)00207-2
    • Tsitsikov EN, Laouini D, Dunn IF, et al. TRAF1 is a negative regulator of TNF signaling. enhanced TNF signaling in TRAF1-deficient mice. Immunity. 2001;15(4):647-657. (Pubitemid 33016449)
    • (2001) Immunity , vol.15 , Issue.4 , pp. 647-657
    • Tsitsikov, E.N.1    Laouini, D.2    Dunn, I.F.3    Sannikova, T.Y.4    Davidson, L.5    Alt, F.W.6    Geha, R.S.7
  • 114
    • 77952239190 scopus 로고    scopus 로고
    • Tumor necrosis factor receptor-associated factor 1 (TRAF1) deficiency attenuates atherosclerosis in mice by impairing monocyte recruitment to the vessel wall
    • Missiou A, Kostlin N, Varo N, et al. Tumor necrosis factor receptor-associated factor 1 (TRAF1) deficiency attenuates atherosclerosis in mice by impairing monocyte recruitment to the vessel wall. Circulation. 2010;121(18):2033-2044.
    • (2010) Circulation. , vol.121 , Issue.18 , pp. 2033-2044
    • Missiou, A.1    Kostlin, N.2    Varo, N.3
  • 116
    • 0030292777 scopus 로고    scopus 로고
    • Targeted disruption of TRAF3 leads to postnatal lethality and defective T-dependent immune responses
    • DOI 10.1016/S1074-7613(00)80497-5
    • Xu Y, Cheng G, Baltimore D. Targeted disruption of TRAF3 leads to postnatal lethality and defective T-dependent immune responses. Immunity. 1996;5(5):407-415. (Pubitemid 26423469)
    • (1996) Immunity , vol.5 , Issue.5 , pp. 407-415
    • Xu, Y.1    Cheng, G.2    Baltimore, D.3
  • 120
    • 0032798623 scopus 로고    scopus 로고
    • Signal transduction by tumor necrosis factor: The Parker B. Francis lectureship
    • DOI 10.1378/chest.116.suppl-1.69S
    • Goeddel DV. Signal transduction by tumor necrosis factor: the Parker B. Francis Lectureship. Chest. 1999;116(1 suppl):69S-73S. (Pubitemid 29340217)
    • (1999) Chest , vol.116 , Issue.SUPPL.
    • Goeddel, D.V.1
  • 124
    • 0032033132 scopus 로고    scopus 로고
    • The death domain kinase RIP mediates the TNF-induced NF-kappaB signal
    • DOI 10.1016/S1074-7613(00)80535-X
    • Kelliher MA, Grimm S, Ishida Y, Kuo F, Stanger BZ, Leder P. The death domain kinase RIP mediates the TNF-induced NF-kappaB signal. Immunity. 1998;8(3):297-303. (Pubitemid 28188890)
    • (1998) Immunity , vol.8 , Issue.3 , pp. 297-303
    • Kelliher, M.A.1    Grimm, S.2    Ishida, Y.3    Kuo, F.4    Stanger, B.Z.5    Leder, P.6
  • 125
    • 0033537767 scopus 로고    scopus 로고
    • Abnormal morphogenesis but intact IKK activation in mice lacking the IKKalpha subunit of IkappaB kinase
    • Hu Y, Baud V, Delhase M, et al. Abnormal morphogenesis but intact IKK activation in mice lacking the IKKalpha subunit of IkappaB kinase. Science. 1999;284(5412):316-320.
    • (1999) Science. , vol.284 , Issue.5412 , pp. 316-320
    • Hu, Y.1    Baud, V.2    Delhase, M.3
  • 131
    • 38849094491 scopus 로고    scopus 로고
    • Act1 modulates autoimmunity through its dual functions in CD40L/BAFF and IL-17 signaling
    • DOI 10.1016/j.cyto.2007.09.015, PII S1043466607004140
    • Li X. Act1 modulates autoimmunity through its dual functions in CD40L/BAFF and IL-17 signaling. Cytokine. 2008;41(2):105-113. (Pubitemid 351192331)
    • (2008) Cytokine , vol.41 , Issue.2 , pp. 105-113
    • Li, X.1
  • 133
    • 0028223847 scopus 로고
    • Generalized lymphoproliferative disease in mice, caused by a point mutation in the Fas ligand
    • DOI 10.1016/0092-8674(94)90375-1
    • Takahashi T, Tanaka M, Brannan CI, et al. Generalized lymphoproliferative disease in mice, caused by a point mutation in the Fas ligand. Cell. 1994;76(6):969-976. (Pubitemid 24106378)
    • (1994) Cell , vol.76 , Issue.6 , pp. 969-976
    • Takahashi, T.1    Tanaka, M.2    Brannan, C.I.3    Jenkins, N.A.4    Copeland, N.G.5    Suda, T.6    Nagata, S.7
  • 134
    • 24644503547 scopus 로고    scopus 로고
    • Mutation identification in a canine model of X-linked ectodermal dysplasia
    • DOI 10.1007/s00335-004-2463-4
    • Casal ML, Scheidt JL, Rhodes JL, Henthorn PS, Werner P. Mutation identification in a canine model of X-linked ectodermal dysplasia. Mamm Genome. 2005;16(7):524-531. (Pubitemid 41278429)
    • (2005) Mammalian Genome , vol.16 , Issue.7 , pp. 524-531
    • Casal, M.L.1    Scheidt, J.L.2    Rhodes, J.L.3    Henthorn, P.S.4    Werner, P.5
  • 137
    • 78650948664 scopus 로고    scopus 로고
    • Onset of autoimmune lymphoproliferative syndrome (ALPS) in humans as a consequence of genetic defect accumulation
    • Magerus-Chatinet A, Neven B, Stolzenberg MC, et al. Onset of autoimmune lymphoproliferative syndrome (ALPS) in humans as a consequence of genetic defect accumulation. J Clin Invest. 2011;121(1):106-112.
    • (2011) J Clin Invest. , vol.121 , Issue.1 , pp. 106-112
    • Magerus-Chatinet, A.1    Neven, B.2    Stolzenberg, M.C.3
  • 140
    • 33644537916 scopus 로고    scopus 로고
    • Deletion of aspartate 182 in OPG causes juvenile Paget's disease by impairing both protein secretion and binding to RANKL
    • Middleton-Hardie C, Zhu Q, Cundy H, et al. Deletion of aspartate 182 in OPG causes juvenile Paget's disease by impairing both protein secretion and binding to RANKL. J Bone Miner Res. 2006;21(3):438-445.
    • (2006) J Bone Miner Res. , vol.21 , Issue.3 , pp. 438-445
    • Middleton-Hardie, C.1    Zhu, Q.2    Cundy, H.3
  • 142
    • 42249095669 scopus 로고    scopus 로고
    • Systemic autoimmunity in BAFF-R-mutant A/WySnJ strain mice
    • Mayne CG, Amanna IJ, Nashold FE, Hayes CE. Systemic autoimmunity in BAFF-R-mutant A/WySnJ strain mice. Eur J Immunol. 2008;38(2): 587-598.
    • (2008) Eur J Immunol. , vol.38 , Issue.2 , pp. 587-598
    • Mayne, C.G.1    Amanna, I.J.2    Nashold, F.E.3    Hayes, C.E.4
  • 143
    • 4644360646 scopus 로고    scopus 로고
    • A rare case of hypohidrotic ectodermal dysplasia caused by compound heterozygous mutations in the EDAR gene
    • DOI 10.1111/j.0022-202X.2004.23405.x
    • Shimomura Y, Sato N, Miyashita A, Hashimoto T, Ito M, Kuwano R. A rare case of hypohidrotic ectodermal dysplasia caused by compound heterozygous mutations in the EDAR gene. J Invest Dermatol. 2004;123(4):649-655. (Pubitemid 39281604)
    • (2004) Journal of Investigative Dermatology , vol.123 , Issue.4 , pp. 649-655
    • Shimomura, Y.1    Sato, N.2    Miyashita, A.3    Hashimoto, T.4    Ito, M.5    Kuwano, R.6
  • 144
    • 77957018085 scopus 로고    scopus 로고
    • Human TRAF3 adaptor molecule deficiency leads to impaired Toll-like receptor 3 response and susceptibility to herpes simplex encephalitis
    • Perez de Diego R, Sancho-Shimizu V, Lorenzo L, et al. Human TRAF3 adaptor molecule deficiency leads to impaired Toll-like receptor 3 response and susceptibility to herpes simplex encephalitis. Immunity. 2010;33(3):400-411.
    • (2010) Immunity. , vol.33 , Issue.3 , pp. 400-411
    • Perez De Diego, R.1    Sancho-Shimizu, V.2    Lorenzo, L.3


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