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Volumn 5, Issue MAR, 2014, Pages

DAMP-Mediated activation of NLRP3-Inflammasome in brain sterile inflammation: The fine line between healing and neurodegeneration

Author keywords

Glia; IL 1beta; Neurotoxicity; NLRP3 inflammasome; Stress

Indexed keywords

ADENOSINE TRIPHOSPHATE; CALCIUM ION; CELL PROTEIN; CRYOPYRIN; CXCL1 CHEMOKINE; DAMAGE ASSOCIATED MOLECULAR PATTERN MOLECULE; INFLAMMASOME; INTERLEUKIN 1BETA; INTERLEUKIN 6; PATTERN RECOGNITION RECEPTOR; POTASSIUM ION; PROTEINASE; REACTIVE OXYGEN METABOLITE; SODIUM ION; UNCLASSIFIED DRUG; URATE;

EID: 84897942258     PISSN: None     EISSN: 16643224     Source Type: Journal    
DOI: 10.3389/fimmu.2014.00099     Document Type: Note
Times cited : (45)

References (8)
  • 1
    • 77953620336 scopus 로고    scopus 로고
    • Inflammation and brain injury: acute cerebral ischaemia, peripheral, and central inflammation
    • doi:10.1016/j.bbi.2009.09.010
    • Denes A, Thornton P, Rothwell NJ, Allan SM. Inflammation and brain injury: acute cerebral ischaemia, peripheral, and central inflammation. Brain Behav Immun (2010) 24:708-23. doi:10.1016/j.bbi.2009.09.010
    • (2010) Brain Behav Immun , vol.24 , pp. 708-723
    • Denes, A.1    Thornton, P.2    Rothwell, N.J.3    Allan, S.M.4
  • 2
    • 84875928941 scopus 로고    scopus 로고
    • Microglia and monocyte-derived macrophages: functionally distinct populations that act in concert in CNS plasticità and repair
    • doi:10.3389/fncel.2013.00034
    • London A, Cohen M, Schwartz M. Microglia and monocyte-derived macrophages: functionally distinct populations that act in concert in CNS plasticità and repair. Front Cell Neurosci (2013) 7:34. doi:10.3389/fncel.2013.00034
    • (2013) Front Cell Neurosci , vol.7 , pp. 34
    • London, A.1    Cohen, M.2    Schwartz, M.3
  • 3
    • 84896702066 scopus 로고    scopus 로고
    • Activation and regulation of cellular inflammasomes: gaps in our knowledge for central nervous system injury
    • doi:10.1038/jcbfm.2013.227
    • de Rivero Vaccari JP, Dietrich WD, Keane RW. Activation and regulation of cellular inflammasomes: gaps in our knowledge for central nervous system injury. J Cereb Blood Flow Metab (2014) 8:1-7. doi:10.1038/jcbfm.2013.227
    • (2014) J Cereb Blood Flow Metab , vol.8 , pp. 1-7
    • de Rivero Vaccari, J.P.1    Dietrich, W.D.2    Keane, R.W.3
  • 4
    • 84874280618 scopus 로고    scopus 로고
    • NLRP3-inflammasome activating DAMPs stimulate an inflammatory response in glia in the absence of priming which contributes to brain inflammation after injury
    • doi:10.3389/fimmu.2012.00288
    • Savage CD, Lopez-Castejon G, Denes A, Brough D. NLRP3-inflammasome activating DAMPs stimulate an inflammatory response in glia in the absence of priming which contributes to brain inflammation after injury. Front Immunol (2012) 3:288. doi:10.3389/fimmu.2012.00288
    • (2012) Front Immunol , vol.3 , pp. 288
    • Savage, C.D.1    Lopez-Castejon, G.2    Denes, A.3    Brough, D.4
  • 5
    • 33845768784 scopus 로고    scopus 로고
    • Microglia-mediated neurotoxicity: uncovering the molecular mechanisms
    • doi:10.1038/nrn2038
    • Block ML, Zecca L, Hong J-S. Microglia-mediated neurotoxicity: uncovering the molecular mechanisms. Nat Rev Neurosci (2007) 8:57-69. doi:10.1038/nrn2038
    • (2007) Nat Rev Neurosci , vol.8 , pp. 57-69
    • Block, M.L.1    Zecca, L.2    Hong, J.-S.3
  • 6
    • 81355146675 scopus 로고    scopus 로고
    • Interplay between redox status and inflammasome activation
    • doi:10.1016/j.it.2011.08.005
    • Rubartelli A, Gattorno M, Netea MG, Dinarello CA. Interplay between redox status and inflammasome activation. Trends Immunol (2011) 32:559-66. doi:10.1016/j.it.2011.08.005
    • (2011) Trends Immunol , vol.32 , pp. 559-566
    • Rubartelli, A.1    Gattorno, M.2    Netea, M.G.3    Dinarello, C.A.4
  • 7
    • 34247880267 scopus 로고    scopus 로고
    • Stress induced morphological microglial activation in the rodent brain: involvement of interleukin-18
    • doi:10.1016/j.neuroscience.2007.02.043
    • Sugama S, Fujita M, Hashimoto M, Conti B. Stress induced morphological microglial activation in the rodent brain: involvement of interleukin-18. Neuroscience (2007) 146:1388-99. doi:10.1016/j.neuroscience.2007.02.043
    • (2007) Neuroscience , vol.146 , pp. 1388-1399
    • Sugama, S.1    Fujita, M.2    Hashimoto, M.3    Conti, B.4
  • 8
    • 0034618862 scopus 로고    scopus 로고
    • The role of the interleukin-1-receptor antagonist in blocking inflammation mediated by interleukin-1
    • doi:10.1056/NEJM200009073431011
    • Dinarello CA. The role of the interleukin-1-receptor antagonist in blocking inflammation mediated by interleukin-1. N Engl J Med (2000) 343:732-4. doi:10.1056/NEJM200009073431011
    • (2000) N Engl J Med , vol.343 , pp. 732-734
    • Dinarello, C.A.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.