A six-color flow cytometry assay for immunophenotyping classical Hodgkin lymphoma in lymph nodes

American Journal of Clinical Pathology

Volumn 141, Issue 3, 2014, Pages 388-396

  Fromm, Jonathan R ^a,b   Wood, Brent L ^a  

^a UNIVERSITY OF WASHINGTON   (United States)

^b UNIVERSITY OF WASHINGTON MEDICAL CENTER   (United States)

Author keywords

Antigen expression; Classical hodgkin lymphoma; Flow cytometry; Hodgkin disease

Indexed keywords

ADULT; AGED; CANCER DIAGNOSIS; CANCER TISSUE; CLASSICAL HODGKIN LYMPHOMA; COLOR; CONFERENCE PAPER; CRYOPRESERVATION; FEMALE; FLOW CYTOMETER; FLOW CYTOMETRY; HUMAN; HUMAN TISSUE; IMMUNOPHENOTYPING; LYMPH NODE; MAJOR CLINICAL STUDY; MALE; MIDDLE AGED; PRIORITY JOURNAL; SENSITIVITY AND SPECIFICITY; TISSUE SECTION; YOUNG ADULT; ADOLESCENT; ANTIGEN EXPRESSION; ARTICLE; HODGKIN DISEASE; IMMUNOLOGY; METHODOLOGY; PATHOLOGY;

ANTIGEN EXPRESSION; CLASSICAL HODGKIN LYMPHOMA; FLOW CYTOMETRY; HODGKIN DISEASE;

ADOLESCENT; ADULT; AGED; FEMALE; FLOW CYTOMETRY; HODGKIN DISEASE; HUMANS; IMMUNOPHENOTYPING; LYMPH NODES; MALE; MIDDLE AGED;

EID: 84897938001     PISSN: 00029173     EISSN: 19437722     Source Type: Journal    
DOI: 10.1309/AJCP0Q1SVOXBHMAM     Document Type: Conference Paper

References (28)

1. Chan WC. The Reed-Sternberg cell in classical Hodgkin's disease. Hematol Oncol. 2001;19:1-17.
2. Kuppers R. The biology of Hodgkin's lymphoma. Nat Rev Cancer. 2009;9:15-27.
3. Marafioti T, Hummel M, Foss HD, et al. Hodgkin and Reed-Sternberg cells represent an expansion of a single clone originating from a germinal center B-cell with functional immunoglobulin gene rearrangements but defective immunoglobulin transcription. Blood. 2000;95:1443-1450.
4. Stein H, Delsol G, Pileri SA, et al. Classical Hodgkin lymphoma, introduction. In: Swerdlow SH, Campos E, Harris NL, et al, eds. WHO Classification of Tumours of Haematopoietic and Lymphoid Tissues. Lyon, France: IARC; 2008:326-329.
5. Stein H, Hummel M. Cellular origin and clonality of classic Hodgkin's lymphoma: immunophenotypic and molecular studies. Semin Hematol. 1999;36:233-241.
6. Dorreen MS, Habeshaw JA, Stansfeld AG, et al. Characteristics of Sternberg-Reed, and related cells in Hodgkin's disease: an immunohistological study. Br J Cancer. 1984;49:465-476.
7. Fromm JR, Kussick SJ, Wood BL. Identification and purification of classical Hodgkin cells from lymph nodes by flow cytometry and flow cytometric cell sorting. Am J Clin Pathol. 2006;126:764-780.
8. Kadin ME, Newcom SR, Gold SB, et al. Origin of Hodgkin's cell [letter]. Lancet. 1974;2:167-168.
9. Payne SV, Jones DB, Wright DH. Reed-Sternberg-cell/ lymphocyte interaction. Lancet. 1977;2:768-769.
10. Payne SV, Newell DG, Jones DB, et al. The Reed-Sternberg cell/lymphocyte interaction: ultrastructure and characteristics of binding. Am J Pathol. 1980;100:7-24.
11. Sanders ME, Makgoba MW, Sussman EH, et al. Molecular pathways of adhesion in spontaneous rosetting of T-lymphocytes to the Hodgkin's cell line L428. Cancer Res. 1988;48:37-40.
12. Stuart AE, Williams AR, Habeshaw JA. Rosetting and other reactions of the Reed-Sternberg cell. J Pathol. 1977;122:81-90.
13. Harris NL. Hodgkin's disease: classification and differential diagnosis. Mod Pathol. 1999;12:159-175.
14. Schmitz R, Stanelle J, Hansmann ML, et al. Pathogenesis of classical and lymphocyte-predominant Hodgkin lymphoma. Annu Rev Pathol. 2009;4:151-174.
15. Craig FE, Foon KA. Flow cytometric immunophenotyping for hematologic neoplasms. Blood. 2008;111:3941-3967.
16. Wood BL, Borowitz MJ. The flow cytometric evaluation of hematopoietic neoplasia. In: McPherson RA, Pincus MR, eds. Henry's Clinical Diagnosis and Management by Laboratory Methods. Philadelphia, PA: Saunders Elsevier; 2011:656-673.
17. Fromm JR, Thomas A, Wood BL. Flow cytometry can diagnose classical Hodgkin lymphoma in lymph nodes with high sensitivity and specificity. Am J Clin Pathol. 2009;131:322-332.
18. Fromm JR, Wood BL. Strategies for immunophenotyping and purifying classical Hodgkin lymphoma cells from lymph nodes by flow cytometry and flow cytometric cell sorting. Methods. 2012;57:368-375.
19. Quintanilla-Martinez L, Fend F, Moguel LR, et al. Peripheral T-cell lymphoma with Reed-Sternberg-like cells of B-cell phenotype and genotype associated with Epstein-Barr virus infection. Am J Surg Pathol. 1999;23:1233-1240.
20. Momose H, Jaffe ES, Shin SS, et al. Chronic lymphocytic leukemia/small lymphocytic lymphoma with Reed-Sternberg-like cells and possible transformation to Hodgkin's disease: mediation by Epstein-Barr virus. Am J Surg Pathol. 1992;16:859-867.
21. Ohno T, Smir BN, Weisenburger DD, et al. Origin of the Hodgkin/Reed-Sternberg cells in chronic lymphocytic leukemia with "Hodgkin's transformation." Blood. 1998;91:1757-1761.
22. Poppema S, Delsol G, Pileri SA, et al. Nodular lymphocyte predominant Hodgkin lymphoma. In: Swerdlow SH, Campos E, Harris NL, et al, eds. WHO Classification of Tumours of Haematopoietic and Lymphoid Tissues. Lyon, France: IARC; 2008:323-325.
23. Carbone A, Gloghini A. The role of current and new discriminating markers in the immunodiagnosis of Hodgkin's disease and other phenotypically related lymphomas. Pathologica. 1996;88:169-174.
24. Carbone A, Gloghini A, Gattei V, et al. Expression of functional CD40 antigen on Reed-Sternberg cells and Hodgkin's disease cell lines. Blood. 1995;85:780-789.
25. Carbone A, Gloghini A, Pinto A. CD40: a sensitive marker of Reed-Sternberg cells. Blood. 1996;87:4918-4919.
26. Fromm JR, Thomas A, Wood BL. Increased expression of T cell antigens on T cells in classical Hodgkin lymphoma. Cytometry B Clin Cytom. 2010;78:387-388.
27. Seegmiller AC, Karandikar NJ, Kroft SH, et al. Overexpression of CD7 in classical Hodgkin lymphomainfiltrating T lymphocytes. Cytometry B Clin Cytom. 2009;76:169-174.
28. Fromm JR. Flow cytometric analysis of CD123 is useful for immunophenotyping classical Hodgkin lymphoma. Cytometry B Clin Cytom. 2011;80:91-99.