Exogenous L-arginine attenuates the effects of angiotensin II on renal hemodynamics and the pressure natriuresis-diuresis relationship

Clinical and Experimental Pharmacology and Physiology

Volumn 41, Issue 4, 2014, Pages 270-278

  Das, Satarupa ^a   Mattson, David L ^a  

^a MEDICAL COLLEGE OF WISCONSIN   (United States)

Author keywords

Blood pressure; L arginine; Nitric oxide; Rats

Indexed keywords

AMINO ACID; ANGIOTENSIN II; ARGININE; ENDOTHELIAL NITRIC OXIDE SYNTHASE; NITRIC OXIDE SYNTHASE; NITRIC OXIDE SYNTHASE INHIBITOR; PHENYLEPHRINE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DIURESIS; FORCE; GLOMERULUS FILTRATION RATE; HYPERTENSION; KIDNEY BLOOD FLOW; KIDNEY DISEASE; KIDNEY PERFUSION; MALE; MICTURITION; NATRIURESIS; NONHUMAN; PERFUSION PRESSURE; RAT; SODIUM EXCRETION; SUPPLEMENTATION; VASCULAR RING; VASCULARIZATION; VASOCONSTRICTION;

BLOOD PRESSURE; L-ARGININE; NITRIC OXIDE; RATS;

ANGIOTENSIN II; ANIMALS; ARGININE; DIURESIS; GLOMERULAR FILTRATION RATE; HEMODYNAMICS; KIDNEY; NATRIURESIS; RATS; RENAL CIRCULATION;

EID: 84897911251     PISSN: 03051870     EISSN: 14401681     Source Type: Journal    
DOI: 10.1111/1440-1681.12212     Document Type: Article

References (37)

1. Chen PY, Sanders PW. Role of nitric oxide synthesis in salt sensitive hypertension in Dahl/Rapp rats. Hypertension 1993; 22: 812-8.
2. Gokce N. L-arginine and hypertension. J. Nutr. 2004; 134: 2807S-11S.
3. Hu L, Manning RD Jr. Role of nitric oxide in regulation of long-term pressure-natriuresis relationship in Dahl rats. Am. J. Physiol. 1995; 268: H2375-83.
4. Miyata N, Zou AP, Mattson DL, Cowley AW Jr. Renal medullary interstitial infusion of L-arginine prevents hypertension in Dahl salt-sensitive rats. Am. J. Physiol. 1998; 275: R1667-73.
5. Patel AR, Granger JP, Kirchner KA. L-Arginine improves transmission of perfusion pressure to the renal interstitium in Dahl salt-sensitive rats. Am. J. Physiol. 1994; 266: R1730-5.
6. Siani A, Pagano E, Iacone R, Iacoviello L, Scopacasa F, Strazzullo P. Blood pressure and metabolic changes during dietary L-arginine supplementation in humans. Am. J. Hypertens. 2000; 13: 547-51.
7. Chen PY, Sanders PW. L-arginine abrogates salt-sensitive hypertension in Dahl/Rapp rats. J. Clin. Invest. 1991; 88: 1559-67.
8. Higashi Y, Oshima T, Ozono R, Wantanabe M, Matsuura H, Kajiyama G. Effects of L-arginine infusion on renal hemodynamics in patients with mild essential hypertension. Hypertension 1995; 25: 898-902.
9. Pagnotta P, Germano G, Grutter G, Leonardo F, Rosano G, Chierchia S. Oral L-arginine supplementation improves essential arterial hypertension. Circulation 1997; 96 (Suppl.): I-538 (Abstract).
10. Mattson DL, Raff H, Roman RJ. Influence of Ang II on pressure natriuresis and renal hemodynamics on volume expanded rats. Am. J. Physiol. 1991; 260: R1200-9.
11. Van der Mark J, Kline RL. Altered pressure natriuresis in chronic Angiotensin II hypertension in rats. Am. J. Physiol. 1994; 266: F739-48.
12. Navar LG, Ichihara A, Chin SY, Imig JD. Nitric oxide-angiotensin II interactions in angiotensin II-dependent hypertension. Acta Physiol. Scand. 2000; 168: 139-47.
13. Rajapakse N, Das S, De Miguel C, Lund H, Mattson DL. Exogenous L-arginine ameliorates angiotensin II-induced hypertension and renal damage in rats. Hypertension 2008; 52: 1086-90.
14. Reckelhoff JF, Romero JC. Role of oxidative stress in angiotensin-induced hypertension. Am. J. Physiol. 2003; 284: R893-912.
15. Kakoki M, Kim H-S, Edgell C-JS, Maeda N, Smithies O, Mattson DL. Amino acids as modulators of endothelium-derived nitric oxide. Am. J. Physiol. 2006; 291: F297-304.
16. Pechman KR, De Miguel C, Lund H, Leonard EC, Basile DP, Mattson DL. Recovery from renal ischemia reperfusion injury is associated with altered renal hemodynamics, blunted pressure natriuresis, and sodium sensitive hypertension. Am. J. Physiol. 2009; 297: R1358-63.
17. Cholewa BC, Meister CJ, Mattson DL. Importance of the renin-angiotensin system in the regulation of arterial blood pressure in conscious mice and rats. Acta Physiol. Scand. 2005; 183: 309-20.
18. Rajapakse N, Mattson DL. Role of L-arginine uptake mechanisms in renal blood flow responses to angiotensin II in rats. Acta Physiol. 2011; 203: 391-400.
19. Kilberg MS, Stevens BR, Novak DA. Recent advances in mammalian amino acid transport. Annu. Rev. Nutr. 1993; 13: 137-65.
20. Sala R, Rotoli BM, Colla E et al. Two-way arginine transport in human endothelial cells: TNF-alpha stimulation is restricted to system y(+). Am. J. Physiol. 2002; 282: C134-43.
21. Simon A, Plies L, Habermeier A, Martiné U, Reining M, Closs EI. Role of neutral amino acid transport and protein breakdown for substrate supply of nitric oxide synthase in human endothelial cells. Circ. Res. 2003; 93: 813-20.
22. Wu F, Cholewa BC, Mattson DL. Characterization of L-arginine transporters in rat renal inner medullary collecting ducts. Am. J. Physiol. 2000; 278: R1506-12.
23. Patel A, Layne S, Watts D, Kirchner KA. L Arg administration normalizes pressure natriuresis in hypertensive Dahl rats. Hypertension 1993; 22: 863-9.
24. Miyata N, Cowley AW Jr. Renal intramedullary infusion of L-Arg prevents reduction in medullary blood flow and hypertension in Dahl salt-sensitive rats. Hypertension 1999; 33: 446-50.
25. Baydoun AR, Emery PW, Pearson JD, Mann GE. Substrate-dependent regulation of intracellular amino acid concentrations in cultured bovine aortic endothelial cells. Biochem. Biophys. Res. Commun. 1990; 173: 940-8.
26. Pollock JS, Förstermann U, Mitchell JA et al. Purification and characterization of particulate endothelium-derived relaxing factor synthase from cultured and native bovine aortic endothelial cells. Proc. Natl Acad. Sci. 1990; 87: 8612-6.
27. Radermacher J, Klanke B, Kastner S et al. Effect of Arg depletion on glomerular and tubular kidney function: Studies in isolated perfused rat kidneys. Am. J. Physiol. 1991; 261: F779-86.
28. Kakoki M, Kim H-S, Arendshorst W, Mattson DL. L-arginine uptake affects nitric oxide production and blood flow in the renal medulla. Am. J. Physiol. 2004; 287: R1478-85.
29. Kakoki M, Wang W, Mattson DL. Cationic amino acid transport in the renal medulla and blood pressure regulation. Hypertension 2002; 39: 287-92.
30. Mattson DL, Meister CJ. Renal cortical and medullary blood flow responses to L-NAME and angiotensin II in wild-type, nNOS null mutant, and eNOS null mutant mice. Am. J. Physiol. 2005; 289: R991-7.
31. Dickhout JG, Mori T, Cowley AW Jr. Buffering of Angiotensin II-induced medullary vasoconstriction. Circ. Res. 2002; 91: 487-93.
32. O'Connor PM, Cowley AW Jr. Medullary thick ascending limb buffer vasoconstriction of renal outer-medullary vasa recta in salt-resistant but not salt-sensitive rats. Hypertension 2012; 60: 965-72.
33. Evans RG, Head GA, Eppel GA, Burke SL, Rajapakse NW. Angiotensin II and neurohumoral control of the renal medullary circulation. Clin. Exp. Pharmacol. Physiol. 2010; 37: e58-69.
34. Sadowski J, Badzynska B. Specific features and roles of renal circulation: Angiotensin II revisited. J. Physiol. Pharmacol. 2006; 57: 169-78.
35. Ballermann BJ, Onuigbo MAC. Angiotensins. In: Fray JCS (ed.). Handbook of Physiology: Section 7, The Endocrine System, Vol III. Endocrine Regulation of Water and Electrolyte Balance. Oxford University Press, New York, NY. 2000; 104-55.
36. Mamanko M, Zaika O, Prieto MC et al. Chronic angiotensin II infusion drives extensive aldosterone-independent epithelial Na+ channel activation. Hypertension 2013; 62: 1111-22.
37. Plato CF, Stoos BA, Wang D, Garvin JL. Endogenous nitric oxide inhibits chloride transport in the thick ascending limb. Am. J. Physiol. 1999; 276: F159-63.