Increased parental history of bipolar disorder in the United States: Association with early age of onset

Acta Psychiatrica Scandinavica

Volumn 129, Issue 5, 2014, Pages 375-382

  Post, R M ^a,b   Leverich, G S ^a   Kupka, R ^c   Keck, Jr ^d,e   Mcelroy, S ^d,e   Altshuler, L ^f,g   Frye, M A ^h   Luckenbaugh, D A ⁱ   Rowe, M ^a   Grunze, H ^j   Suppes, T ^k,l   Nolen, W A ^m  

^a Bipolar Collaborative Network   (United States)

^b GEORGE WASHINGTON UNIVERSITY SCHOOL OF MEDICINE AND HEALTH SCIENCES   (United States)

^c VU UNIVERSITY MEDICAL CENTER   (Netherlands)

^d UNIVERSITY OF CINCINNATI COLLEGE OF MEDICINE   (United States)

^e LINDNER CENTER OF HOPE   (United States)

^f UNIVERSITY OF CALIFORNIA   (United States)

^g VA GREATER LOS ANGELES HEALTHCARE SYSTEM   (United States)

^h MAYO CLINIC   (United States)

ⁱ NATIONAL INSTITUTE OF MENTAL HEALTH   (United States)

^j NEWCASTLE UNIVERSITY   (United Kingdom)

^k STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

^l VA PALO ALTO HEALTH CARE SYSTEM   (United States)

^m UNIVERSITY MEDICAL CENTER GRONINGEN   (Netherlands)

more..

Author keywords

Assortative mating; Bipolar disorder; Childhood onset bipolar disorder; Genetics

Indexed keywords

ADULT; ARTICLE; BIPOLAR DEPRESSION; BIPOLAR DISORDER; FAMILY HISTORY; HUMAN; MAJOR CLINICAL STUDY; MAJOR DEPRESSION; MOOD DISORDER; ONSET AGE; PARENTAL HISTORY; PRIORITY JOURNAL; SELF REPORT; UNITED STATES; AFFECTIVE SYMPTOMS; CHILD; CULTURAL FACTOR; DEPRESSION; EPIDEMIOLOGY; ETHNOLOGY; FAMILY HEALTH; FEMALE; GERMANY; MALE; NETHERLANDS; PARENT; PREVALENCE; PROGNOSIS; PSYCHOLOGICAL RATING SCALE; PSYCHOLOGY; RISK FACTOR;

ADULT; AFFECTIVE SYMPTOMS; AGE OF ONSET; BIPOLAR DISORDER; CHILD OF IMPAIRED PARENTS; CROSS-CULTURAL COMPARISON; DEPRESSIVE DISORDER; FAMILY HEALTH; FEMALE; GERMANY; HUMANS; MALE; NETHERLANDS; PARENTS; PREVALENCE; PROGNOSIS; PSYCHIATRIC STATUS RATING SCALES; RISK FACTORS; SELF REPORT; UNITED STATES;

EID: 84897904956     PISSN: 0001690X     EISSN: 16000447     Source Type: Journal    
DOI: 10.1111/acps.12208     Document Type: Article

References (25)

1. Post RM, Leverich GS, Kupka RW et al. Early-onset bipolar disorder and treatment delay are risk factors for poor outcome in adulthood. J Clin Psychiatry 2010;71:864-872.
2. Post R, Leverich G, Altshuler L et al. Differential clinical characteristics, medication usage, and treatment response in the U.S. versus the Netherlands and Germany. Int Clin Psychopharmacol 2011;26:96-106.
3. Lapalme M, Hodgins S, Laroche C. Children of parents with bipolar disorder: a metaanalysis of risk for mental disorders. Can J Psychiatry 1997;42:623-631.
4. Gottesman II, Laursen TM, Bertelsen A, Mortensen PB. Severe mental disorders in offspring with 2 psychiatrically ill parents. Arch Gen Psychiatry 2010;67:252-257.
5. Post RM, Denicoff KD, Leverich GS et al. Morbidity in 258 bipolar outpatients followed for 1 year with daily prospective ratings on the NIMH life chart method. J Clin Psychiatry 2003;64:680-690; quiz 738-689.
6. Post RM, Altshuler LL, Frye MA et al. Complexity of pharmacologic treatment required for sustained improvement in outpatients with bipolar disorder. J Clin Psychiatry 2010;71:1176-1186; quiz 1252-1173.
7. Post RM, Leverich GS. Treatment of bipolar illness: a casebook for clinicians and patients. New York: W.W. Norton & Company, 2008. 665 p.
8. Kupka RW, Luckenbaugh DA, Post RM et al. Comparison of rapid-cycling and non-rapid-cycling bipolar disorder based on prospective mood ratings in 539 outpatients. Am J Psychiatry 2005;162:1273-1280.
9. Lin PI, McInnis MG, Potash JB et al. Clinical correlates and familial aggregation of age at onset in bipolar disorder. Am J Psychiatry 2006;163:240-246.
10. Bellivier F, Etain B, Malafosse A et al. Age at onset in bipolar I affective disorder in the USA and Europe. World J Biol Psychiatry [Internet]. 2011 Dec 21. Available from: http://www.ncbi.nlm.nih.gov/pubmed/22188366.
11. Etain B, Lajnef M, Bellivier F, Mathieu F, Raust A, Cochet B, et al. Clinical expression of bipolar disorder type I as a function of age and polarity at onset: convergent findings in samples from France and the United States. J Clin Psychiatry 2012;73:e561-e566.
12. Craddock N, Owen M. Molecular genetics and the Kraepelinian dichotomy: one disorder, two disorders, or do we need to start thinking afresh? Psychiatr Ann 2010;40:88-91.
13. Weissman MM, Pilowsky DJ, Wickramaratne PJ et al. Remissions in maternal depression and child psychopathology: a STAR*D-child report. JAMA 2006;295:1389-1398.
14. Wickramaratne P, Gameroff MJ, Pilowsky DJ et al. Children of depressed mothers 1 year after remission of maternal depression: findings from the STAR*D-Child study. Am J Psychiatry 2011;168:593-602.
15. Roth TL, Lubin FD, Funk AJ, Sweatt JD. Lasting epigenetic influence of early-life adversity on the BDNF gene. Biol Psychiatry 2009;65:760-769.
16. Krishnan V, Han MH, Graham DL et al. Molecular adaptations underlying susceptibility and resistance to social defeat in brain reward regions. Cell 2007;131:391-404.
17. Nestler EJ. Review. Transcriptional mechanisms of addiction: role of DeltaFosB. Philos Trans R Soc Lond 2008;363:3245-3255.
18. Post RM, Miklowitz D. The role of stress in the onset, course, and progression of bipolar illness and its comorbidites: implications for therapeutics. In: Miklowitz D, Cicchetti D, eds. Bipolar disorder: a developmental psychopathology approach. New York: Guilford Press, 2010: 370-416.
19. Post R, Kauer-Sant'anna M. An introduction to the neurobiology of bipolar illness onset, recurrence and progression. In: Yatham L, Maj M, eds. Bipolar disorder: clinical and neurobiological foundations. New York, NY: John WIley & Sons, 2010: 96-109.
20. Post RM, Kalivas P. Bipolar disorder and substance misuse: pathological and therapeutic implications of their comorbidity and cross-sensitisation. Br J Psychiatry 2013;202:172-176.
21. Nestler EJ, ed. New Targets for Depression Treatment from Gene and Chromatin Arrays. American College of Neuropsychopharmacology 48th Annual Meeting 2009; Hollywood, Florida.
22. Feinberg A, Irizarry R, eds. Stochastic epigenetic variation as a driving force of development, evolutionary adaptation, and disease. Proc Natl Acad Sci U S A 2010;107 (Suppl 1):1757-1764.
23. Lange KJ, McInnis MG. Studies of anticipation in bipolar affective disorder. CNS Spectr 2002;7:196-202.
24. Drancourt N, Etain B, Lajnef M, Henry C, Raust A, Cochet B, et al. Duration of untreated bipolar disorder: missed opportunities on the long road to optimal treatment. Acta Psychiatr Scand 2013;127:136-144.
25. Post RM, Chang K, Frye MA. Paradigm shift: preliminary clinical categorization of ultrahigh risk for childhood bipolar disorder to facilitate studies on prevention. J Clin Psychiatry 2013;74:167-169.