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Volumn 8, Issue , 2014, Pages 107-114

Biologics: The role of delivery systems in improved therapy

Author keywords

Biologics; Drug delivery systems; Medical devices

Indexed keywords

BILOSOME; BIOLOGICAL PRODUCT; DRUG CARRIER; LIPOSOME; MICROSPHERE; NANOPARTICLE; POLYGLACTIN; POLYLACTIC ACID; SOLID LIPID MICROPARTICLE; UNCLASSIFIED DRUG;

EID: 84897854012     PISSN: 11775475     EISSN: 11775491     Source Type: Journal    
DOI: 10.2147/BTT.S38387     Document Type: Review
Times cited : (86)

References (51)
  • 1
    • 84856720002 scopus 로고    scopus 로고
    • Fresh from the biotech pipeline - 2011
    • Kling J. Fresh from the biotech pipeline - 2011. Nat Biotechnol. 2012;30(2):128-131.
    • (2012) Nat Biotechnol , vol.30 , Issue.2 , pp. 128-131
    • Kling, J.1
  • 2
    • 77957361348 scopus 로고    scopus 로고
    • Development trends for human monoclonal antibody therapeutics
    • Nelson AL, Dhimolea E, Reichert JM. Development trends for human monoclonal antibody therapeutics. Nat Rev Drug Discov. 2010;9(10): 767-774.
    • (2010) Nat Rev Drug Discov , vol.9 , Issue.10 , pp. 767-774
    • Nelson, A.L.1    Dhimolea, E.2    Reichert, J.M.3
  • 3
    • 84881025893 scopus 로고    scopus 로고
    • Pharmacokinetic studies of protein drugs: Past, present and future
    • Ezan E. Pharmacokinetic studies of protein drugs: past, present and future. Adv Drug Deliv Rev. 2013;65(8):1065-1073.
    • (2013) Adv Drug Deliv Rev , vol.65 , Issue.8 , pp. 1065-1073
    • Ezan, E.1
  • 4
    • 84889082081 scopus 로고    scopus 로고
    • Cell-specifc delivery of biologicals: Problems, pitfalls and possibilities of antifbrotic compounds in the liver
    • Poelstra K, Beljaars L, Melgert BN. Cell-specifc delivery of biologicals: problems, pitfalls and possibilities of antifbrotic compounds in the liver. Drug Discov Today. 2013;18(23-24):1237-1242.
    • (2013) Drug Discov Today , vol.18 , Issue.23-24 , pp. 1237-1242
    • Poelstra, K.1    Beljaars, L.2    Melgert, B.N.3
  • 5
    • 84861805671 scopus 로고    scopus 로고
    • Strategies for non-invasive delivery of biologics
    • Chung S W, Hil-lal TA, Byun Y. Strategies for non-invasive delivery of biologics. J Drug Target. 2012;20(6):481-501.
    • (2012) J Drug Target , vol.20 , Issue.6 , pp. 481-501
    • Chung, S.W.1    Hil-Lal, T.A.2    Byun, Y.3
  • 6
    • 37749004225 scopus 로고    scopus 로고
    • Protein therapeutics: A summary and pharmacological classifcation
    • Leader B, Baca QJ, Golan DE. Protein therapeutics: a summary and pharmacological classifcation. Nat Rev Drug Discov. 2008;7(1):21-39.
    • (2008) Nat Rev Drug Discov , vol.7 , Issue.1 , pp. 21-39
    • Leader, B.1    Baca, Q.J.2    Golan, D.E.3
  • 7
    • 84869115847 scopus 로고    scopus 로고
    • Challenges and opportunities in absorption, distribution, metabolism and excretion studies of therapeutic biologicals
    • Xu X, Vugmeyster Y. Challenges and opportunities in absorption, distribution, metabolism and excretion studies of therapeutic biologicals. AAPS J. 2012;14(4):781-791.
    • (2012) AAPS J , vol.14 , Issue.4 , pp. 781-791
    • Xu, X.1    Vugmeyster, Y.2
  • 8
    • 79958811141 scopus 로고    scopus 로고
    • A new roadmap for biopharmaceutical drug product development: Integrating development, validation and quality by design
    • Martin-Moe S, Lim FJ, Wong RL, Sreedhara A, Sundaram J, Sane SU. A new roadmap for biopharmaceutical drug product development: integrating development, validation and quality by design. J Pharm Sci. 2011;100(8):3031-3043.
    • (2011) J Pharm Sci , vol.100 , Issue.8 , pp. 3031-3043
    • Martin-Moe, S.1    Lim, F.J.2    Wong, R.L.3    Sreedhara, A.4    Sundaram, J.5    Sane, S.U.6
  • 9
    • 84877793934 scopus 로고    scopus 로고
    • Parenteral biologics delivery: Recent progresses, key challenges and perspectives
    • Richard J. Parenteral biologics delivery: recent progresses, key challenges and perspectives. European Journal of Parenteral and Pharmaceutical Sciences. 2012;17(3):94-109.
    • (2012) European Journal of Parenteral and Pharmaceutical Sciences , vol.17 , Issue.3 , pp. 94-109
    • Richard, J.1
  • 10
    • 81855170441 scopus 로고    scopus 로고
    • Nanomedicine(s) under the microscope
    • Duncan R, Gaspar R. Nanomedicine(s) under the microscope. Mol Pharm. 2011;8(6):2101-2141.
    • (2011) Mol Pharm , vol.8 , Issue.6 , pp. 2101-2141
    • Duncan, R.1    Gaspar, R.2
  • 11
    • 84856389509 scopus 로고    scopus 로고
    • RNA-based therapeutics: Current progress and future prospects
    • Burnett JC, Rossi JJ. RNA-based therapeutics: current progress and future prospects. Chem Biol. 2012;19(1):60-71.
    • (2012) Chem Biol , vol.19 , Issue.1 , pp. 60-71
    • Burnett, J.C.1    Rossi, J.J.2
  • 12
    • 84889080018 scopus 로고    scopus 로고
    • Current challenges and opportunities in nonclinical safety testing of biologics
    • Kronenberg S, Baumann A, de Haan L, et al. Current challenges and opportunities in nonclinical safety testing of biologics. Drug Discov Today. 2013;18(23-24):1138-1143.
    • (2013) Drug Discov Today , vol.18 , Issue.23-24 , pp. 1138-1143
    • Kronenberg, S.1    Baumann, A.2    de Haan, L.3
  • 13
    • 84864762825 scopus 로고    scopus 로고
    • Optimizing drug delivery for modern biologics
    • Burgess BE. Optimizing drug delivery for modern biologics. BioPharm International. 2012;25(5):30-32.
    • (2012) BioPharm International , vol.25 , Issue.5 , pp. 30-32
    • Burgess, B.E.1
  • 14
    • 79955840998 scopus 로고    scopus 로고
    • Human growth hormone: New delivery systems, alternative routes of administration, and their pharmacological relevance
    • Cázares-Delgadillo J, Ganem-Rondero A, Kalia YN. Human growth hormone: new delivery systems, alternative routes of administration, and their pharmacological relevance. Eur J Pharm Biopharm. 2011;78(2): 278-288.
    • (2011) Eur J Pharm Biopharm , vol.78 , Issue.2 , pp. 278-288
    • Cázares-Delgadillo, J.1    Ganem-Rondero, A.2    Kalia, Y.N.3
  • 15
    • 0035850227 scopus 로고    scopus 로고
    • Lipid microparticles as a parenteral controlled release device for peptides
    • Reithmeier H, Hermann J, Gopferich A. Lipid microparticles as a parenteral controlled release device for peptides. J Control Release. 2001;73(2-3):339-350.
    • (2001) J Control Release , vol.73 , Issue.2-3 , pp. 339-350
    • Reithmeier, H.1    Hermann, J.2    Gopferich, A.3
  • 16
    • 24044485078 scopus 로고    scopus 로고
    • Novel long-acting formulation of human growth hormone
    • Govardhan C, Khalaf N, Jung C W, et al. Novel long-acting formulation of human growth hormone. Pharm Res. 2005;22(9):1461-1470.
    • (2005) Pharm Res , vol.22 , Issue.9 , pp. 1461-1470
    • Govardhan, C.1    Khalaf, N.2    Jung, C.W.3
  • 17
    • 3042771832 scopus 로고    scopus 로고
    • Oral delivery of macromolecules using intestinal patches: Applications for insulin delivery
    • Whitehead K, Shen Z, Mitragotri S. Oral delivery of macromolecules using intestinal patches: applications for insulin delivery. J Control Release. 2004;98(1):37-45.
    • (2004) J Control Release , vol.98 , Issue.1 , pp. 37-45
    • Whitehead, K.1    Shen, Z.2    Mitragotri, S.3
  • 18
    • 84859720244 scopus 로고    scopus 로고
    • Oral biodrug delivery using cell-penetrating peptide
    • El Khafagy S, Morishita M. Oral biodrug delivery using cell-penetrating peptide. Adv Drug Del Rev. 2012;64(6):531-539.
    • (2012) Adv Drug Del Rev , vol.64 , Issue.6 , pp. 531-539
    • El Khafagy, S.1    Morishita, M.2
  • 19
    • 77956434412 scopus 로고    scopus 로고
    • Nanotechnology in drug delivery and tissue engineering: From discovery to applications
    • Shi J, Votruba AR, Farokhzad OC, Langer R. Nanotechnology in drug delivery and tissue engineering: from discovery to applications. Nano Lett. 2010;10(9):3223-3230.
    • (2010) Nano Lett , vol.10 , Issue.9 , pp. 3223-3230
    • Shi, J.1    Votruba, A.R.2    Farokhzad, O.C.3    Langer, R.4
  • 20
    • 60849130683 scopus 로고    scopus 로고
    • In vivo evaluation of safety and effcacy of self-assembled nanoparticles for oral insulin delivery
    • Sonaje K, Lin YH, Juang JH, Wey S P, Chen CT, Sung H W. In vivo evaluation of safety and effcacy of self-assembled nanoparticles for oral insulin delivery. Biomaterials. 2009;30(12):2329-2339.
    • (2009) Biomaterials , vol.30 , Issue.12 , pp. 2329-2339
    • Sonaje, K.1    Lin, Y.H.2    Juang, J.H.3    Wey, S.P.4    Chen, C.T.5    Sung, H.W.6
  • 21
    • 84865580901 scopus 로고    scopus 로고
    • Nanomedicine for treatment of diabetes in an aging population: State-of-the-art and future developments
    • Krol S, Ellis-Behke R, Marchetti P. Nanomedicine for treatment of diabetes in an aging population: state-of-the-art and future developments. Nanomedicine. 2012;8(Suppl 1):S69-S76.
    • (2012) Nanomedicine , vol.8 , Issue.SUPPL. 1
    • Krol, S.1    Ellis-Behke, R.2    Marchetti, P.3
  • 22
    • 60149089459 scopus 로고    scopus 로고
    • Barrier properties of mucus
    • Cone RA. Barrier properties of mucus. Adv Drug Deliv Rev. 2009;61(2): 75-85.
    • (2009) Adv Drug Deliv Rev , vol.61 , Issue.2 , pp. 75-85
    • Cone, R.A.1
  • 23
    • 67349139863 scopus 로고    scopus 로고
    • The complexation between novel comb shaped amphiphilic polyallylamine and insulin: Towards oral insulin delivery
    • Thompson CJ, Tetley L, Uchegbu IF, Cheng W P. The complexation between novel comb shaped amphiphilic polyallylamine and insulin: towards oral insulin delivery. Int J Pharm. 2009;376(1-2):46-55.
    • (2009) Int J Pharm , vol.376 , Issue.1-2 , pp. 46-55
    • Thompson, C.J.1    Tetley, L.2    Uchegbu, I.F.3    Cheng, W.P.4
  • 24
    • 72449211710 scopus 로고    scopus 로고
    • M-cell targeted delivery of recombinant hepatitis B surface antigen using cholera toxin B subunit conjugated bilosomes
    • Shukla A, Katare O P, Singh B, Vyas S P. M-cell targeted delivery of recombinant hepatitis B surface antigen using cholera toxin B subunit conjugated bilosomes. Int J Pharm. 2010;385(1-2):47-52.
    • (2010) Int J Pharm , vol.385 , Issue.1-2 , pp. 47-52
    • Shukla, A.1    Katare, O.P.2    Singh, B.3    Vyas, S.P.4
  • 25
    • 84862833264 scopus 로고    scopus 로고
    • Liposomes containing glycocholate as potential oral insulin delivery systems: Preparation, in vitro characterization, and improved protection against enzymatic degradation
    • Niu M, Lu Y, Hovgaard L, Wu W. Liposomes containing glycocholate as potential oral insulin delivery systems: preparation, in vitro characterization, and improved protection against enzymatic degradation. Int J Nanomedicine. 2011;6:1155-1166.
    • (2011) Int J Nanomedicine , vol.6 , pp. 1155-1166
    • Niu, M.1    Lu, Y.2    Hovgaard, L.3    Wu, W.4
  • 26
    • 16244422972 scopus 로고    scopus 로고
    • Investigation of lectin-modifed insulin liposomes as carriers for oral administration
    • Zhang N, Ping QN, Huang GH, Xu WF. Investigation of lectin-modifed insulin liposomes as carriers for oral administration. Int J Pharm. 2005;294(1-2):247-259.
    • (2005) Int J Pharm , vol.294 , Issue.1-2 , pp. 247-259
    • Zhang, N.1    Ping, Q.N.2    Huang, G.H.3    Xu, W.F.4
  • 27
    • 38349112036 scopus 로고    scopus 로고
    • Improved intestinal absorption of calcitonin by mucoadhesive delivery of novel pectin-liposome nanocomplexes
    • Thirawong N, Thongborisute J, Takeuchi H, Sriamornsak P. Improved intestinal absorption of calcitonin by mucoadhesive delivery of novel pectin-liposome nanocomplexes. J Control Release. 2008;125(3):236-245.
    • (2008) J Control Release , vol.125 , Issue.3 , pp. 236-245
    • Thirawong, N.1    Thongborisute, J.2    Takeuchi, H.3    Sriamornsak, P.4
  • 28
    • 26644454810 scopus 로고    scopus 로고
    • The basics and underlying mechanisms of mucoadhesion
    • Smart JD. The basics and underlying mechanisms of mucoadhesion. Adv Drug Deliv Rev. 2005;57(11):1556-1568.
    • (2005) Adv Drug Deliv Rev , vol.57 , Issue.11 , pp. 1556-1568
    • Smart, J.D.1
  • 31
    • 33746474818 scopus 로고    scopus 로고
    • Polyionic hydrocolloids for the intestinal delivery of protein drugs: Alginate and chitosan - a review
    • George M, Abraham TE. Polyionic hydrocolloids for the intestinal delivery of protein drugs: alginate and chitosan - a review. J Control Release. 2006;114(1):1-14.
    • (2006) J Control Release , vol.114 , Issue.1 , pp. 1-14
    • George, M.1    Abraham, T.E.2
  • 32
    • 82455219467 scopus 로고    scopus 로고
    • A review of the efficacy and safety of nanoparticle-based oral insulin delivery systems
    • Card J W, Magnuson BA. A review of the efficacy and safety of nanoparticle-based oral insulin delivery systems. Am J Physiol Gastrointest Liver Physiol. 2011;301(6):G956-G967.
    • (2011) Am J Physiol Gastrointest Liver Physiol , vol.301 , Issue.6
    • Card, J.W.1    Magnuson, B.A.2
  • 33
    • 0037459005 scopus 로고    scopus 로고
    • Nasal drug delivery - possibilities, problems and solutions
    • Illum L. Nasal drug delivery - possibilities, problems and solutions. J Control Release. 2003;87(1-3):187-198.
    • (2003) J Control Release , vol.87 , Issue.1-3 , pp. 187-198
    • Illum, L.1
  • 35
    • 78650388990 scopus 로고    scopus 로고
    • Nasal delivery of recombinant human growth hormone: In vivo evaluation with Pheroid technology and N- trimethyl chitosan chloride
    • Steyn D, Du Plessis L, Kotzé A. Nasal delivery of recombinant human growth hormone: in vivo evaluation with Pheroid technology and N- trimethyl chitosan chloride. J Pharm Pharm Sci. 2010;13(2): 263-273.
    • (2010) J Pharm Pharm Sci , vol.13 , Issue.2 , pp. 263-273
    • Steyn, D.1    Du Plessis, L.2    Kotzé, A.3
  • 36
    • 72149107329 scopus 로고    scopus 로고
    • Enhancement of nasal and intestinal calcitonin delivery by the novel Pheroid fatty acid based delivery system, and by N-trimethyl chitosan chloride
    • Du Plessis LH, Lubbe J, Strauss T, Kotzé AF. Enhancement of nasal and intestinal calcitonin delivery by the novel Pheroid fatty acid based delivery system, and by N-trimethyl chitosan chloride. Int J Pharm. 2010;385(1-2):181-186.
    • (2010) Int J Pharm , vol.385 , Issue.1-2 , pp. 181-186
    • du Plessis, L.H.1    Lubbe, J.2    Strauss, T.3    Kotzé, A.F.4
  • 37
    • 77949833508 scopus 로고    scopus 로고
    • Intranasal delivery to the central nervous system: Mechanism and experimental considerations
    • Dhuria S V, Hanson LR, Frey WH. Intranasal delivery to the central nervous system: mechanism and experimental considerations. J Pharm Sci. 2010;93(4):1654-1673.
    • (2010) J Pharm Sci , vol.93 , Issue.4 , pp. 1654-1673
    • Dhuria, S.V.1    Hanson, L.R.2    Frey, W.H.3
  • 38
    • 84860193946 scopus 로고    scopus 로고
    • Intranasal delivery of biologics to the central nervous system
    • Lochhead JJ, Thorne RG. Intranasal delivery of biologics to the central nervous system. Adv Drug Del Rev. 2012;64(7):614-628.
    • (2012) Adv Drug Del Rev , vol.64 , Issue.7 , pp. 614-628
    • Lochhead, J.J.1    Thorne, R.G.2
  • 39
    • 0035719828 scopus 로고    scopus 로고
    • The lung as a route for systemic delivery of therapeutic proteins and peptides
    • Agu RU, Ugwoke MI, Armand M, Kinget R, Verbeke N. The lung as a route for systemic delivery of therapeutic proteins and peptides. Respir Res. 2001;2(4):198-209.
    • (2001) Respir Res , vol.2 , Issue.4 , pp. 198-209
    • Agu, R.U.1    Ugwoke, M.I.2    Armand, M.3    Kinget, R.4    Verbeke, N.5
  • 40
    • 28044473874 scopus 로고    scopus 로고
    • Emerging strategies for the transdermal delivery of peptide and protein drugs
    • Schuetz YB, Naik A, Guy RH, Kalia YN. Emerging strategies for the transdermal delivery of peptide and protein drugs. Expert Opin Drug Deliv. 2005;2(3):533-548.
    • (2005) Expert Opin Drug Deliv , vol.2 , Issue.3 , pp. 533-548
    • Schuetz, Y.B.1    Naik, A.2    Guy, R.H.3    Kalia, Y.N.4
  • 41
    • 84859586554 scopus 로고    scopus 로고
    • Enhanced percutaneous delivery of recombinant human epidermal growth factor employing nano-liposome system
    • Jeon SO, Hwang HJ, Oh DH, et al. Enhanced percutaneous delivery of recombinant human epidermal growth factor employing nano-liposome system. J Microencapsul. 2012;29(3):234-241.
    • (2012) J Microencapsul , vol.29 , Issue.3 , pp. 234-241
    • Jeon, S.O.1    Hwang, H.J.2    Oh, D.H.3
  • 42
    • 84865414923 scopus 로고    scopus 로고
    • Novel lyophilized hydrogel patches for convenient and effective administration of microneedle-mediated insulin delivery
    • Qiu Y, Qin G, Zhang S, Wu Y, Xu B, Gao Y. Novel lyophilized hydrogel patches for convenient and effective administration of microneedle-mediated insulin delivery. Int J Pharm. 2012;437(1-2):51-56.
    • (2012) Int J Pharm , vol.437 , Issue.1-2 , pp. 51-56
    • Qiu, Y.1    Qin, G.2    Zhang, S.3    Wu, Y.4    Xu, B.5    Gao, Y.6
  • 43
    • 84883812844 scopus 로고    scopus 로고
    • Nanopharmaceuticals for improved topical vaginal therapy: Can they deliver?
    • Vanić Z, Škalko-Basnet N. Nanopharmaceuticals for improved topical vaginal therapy: can they deliver? Eur J Pharm Sci. 2013;50(1): 29-41.
    • (2013) Eur J Pharm Sci , vol.50 , Issue.1 , pp. 29-41
    • Vanić, Z.1    Škalko-Basnet, N.2
  • 44
    • 40649101153 scopus 로고    scopus 로고
    • Thermo-sensitive and biodegradable hydrogels based on stereocomplexed Pluronic multi-block copoly-mers for controlled protein delivery
    • Chung HJ, Lee Y, Park TG. Thermo-sensitive and biodegradable hydrogels based on stereocomplexed Pluronic multi-block copoly-mers for controlled protein delivery. J Control Release. 2008;127(1): 22-30.
    • (2008) J Control Release , vol.127 , Issue.1 , pp. 22-30
    • Chung, H.J.1    Lee, Y.2    Park, T.G.3
  • 45
    • 41349105238 scopus 로고    scopus 로고
    • In situ gelling hydrogels for pharmaceutical and biomedical applications
    • Van Tomme SR, Storm G, Hennink WE. In situ gelling hydrogels for pharmaceutical and biomedical applications. Int J Pharm. 2008;355(1-2):1-18.
    • (2008) Int J Pharm , vol.355 , Issue.1-2 , pp. 1-18
    • van Tomme, S.R.1    Storm, G.2    Hennink, W.E.3
  • 46
    • 72149125853 scopus 로고    scopus 로고
    • Sustained release hGH microsphere formulation produced by a novel supercritical fuid technology: In vivo studies
    • Jordan F, Naylor A, Kelly CA, Howdle SM, Lewis A, Illum L. Sustained release hGH microsphere formulation produced by a novel supercritical fuid technology: in vivo studies. J Control Release. 2010;141(1): 153-160.
    • (2010) J Control Release , vol.141 , Issue.1 , pp. 153-160
    • Jordan, F.1    Naylor, A.2    Kelly, C.A.3    Howdle, S.M.4    Lewis, A.5    Illum, L.6
  • 47
    • 0036888513 scopus 로고    scopus 로고
    • Biocompatibility and degradation of poly(ether-ester) microspheres: In vitro and in vivo evaluation
    • van Dijkhuizen-Radersma R, Hesseling SC, Kaim PE, De Groot K, Bezemer JM. Biocompatibility and degradation of poly(ether-ester) microspheres: in vitro and in vivo evaluation. Biomaterials. 2002;23(24):4719-4729.
    • (2002) Biomaterials , vol.23 , Issue.24 , pp. 4719-4729
    • van Dijkhuizen-Radersma, R.1    Hesseling, S.C.2    Kaim, P.E.3    de Groot, K.4    Bezemer, J.M.5
  • 48
    • 33845945504 scopus 로고    scopus 로고
    • Development of a spray congealing process for the preparation of insulin-loaded lipid microparticles and characterization thereof
    • Maschke A, Becker C, Eyrich D, Kiermaier J, Blunk T, Göpferich A. Development of a spray congealing process for the preparation of insulin-loaded lipid microparticles and characterization thereof. Eur J Pharm Biopharm. 2007;65(2):175-187.
    • (2007) Eur J Pharm Biopharm , vol.65 , Issue.2 , pp. 175-187
    • Maschke, A.1    Becker, C.2    Eyrich, D.3    Kiermaier, J.4    Blunk, T.5    Göpferich, A.6
  • 49
    • 34547908177 scopus 로고    scopus 로고
    • Review on Medusa®: A polymer-based sustained release technology for protein and peptide drugs
    • Chan Y P, Meyruiex R, Kravtzoff R, Nicolas F, Lundstrom K. Review on Medusa®: a polymer-based sustained release technology for protein and peptide drugs. Expert Opin Drug Deliv. 2007;4(4):441-451.
    • (2007) Expert Opin Drug Deliv , vol.4 , Issue.4 , pp. 441-451
    • Chan, Y.P.1    Meyruiex, R.2    Kravtzoff, R.3    Nicolas, F.4    Lundstrom, K.5
  • 50
    • 84856806928 scopus 로고    scopus 로고
    • Three-year effcacy and safety of LB03002, a once-weekly sustained-release growth hormone (GH) preparation, in prepubertal children with GH defciency (GHD)
    • Peter F, Bidlingmaier M, Savoy C, Ji HJ, Saenger PH. Three-year effcacy and safety of LB03002, a once-weekly sustained-release growth hormone (GH) preparation, in prepubertal children with GH defciency (GHD). J Clin Endocrinol Metab. 2012;97(2):400-407.
    • (2012) J Clin Endocrinol Metab , vol.97 , Issue.2 , pp. 400-407
    • Peter, F.1    Bidlingmaier, M.2    Savoy, C.3    Ji, H.J.4    Saenger, P.H.5
  • 51


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