A scoring strategy combining statistics and functional genomics supports a possible role for common polygenic variation in autism

Frontiers in Genetics

Volumn 5, Issue FEB, 2014, Pages

  Carayol, Jérôme ^a   Schellenberg, Gerard D ^b   Dombroski, Beth ^b   Amiet, Claire ^a   Génin, Bérengère ^a   Fontaine, Karine ^a   Rousseau, Francis ^a   Vazart, Céline ^a   Cohen, David ^c   Frazier, Thomas W ^d   Hardan, Antonio Y ^e   Dawson, Geraldine ^f   Frio, Thomas Rio ^a  

^a Integragen   (France)

^b UNIVERSITY OF PENNSYLVANIA   (United States)

^c PITIÉ SALPÊTRIÈRE HOSPITAL   (France)

^d LERNER RESEARCH INSTITUTE   (United States)

^e STANFORD UNIVERSITY   (United States)

^f DUKE UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

Autism; Common variants; Functional genomics; Genetic score; Genetic variance; Polygenic model

Indexed keywords

PLASMINOGEN ACTIVATOR; UROKINASE RECEPTOR;

ALLELE; ARTICLE; AUTISM; CASE CONTROL STUDY; DOMINANT INHERITANCE; FEMALE; FUNCTIONAL GENOMICS; GENETIC RISK; GENETIC VARIABILITY; GENOTYPE; HUMAN; MALE; MULTIFACTORIAL INHERITANCE; NERVE CELL DIFFERENTIATION; NONHUMAN; PHENOTYPE; SCORING SYSTEM; SIBLING; SINGLE NUCLEOTIDE POLYMORPHISM;

EID: 84897728392     PISSN: None     EISSN: 16648021     Source Type: Journal    
DOI: 10.3389/fgene.2014.00033     Document Type: Article

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