Serumendothelin-1 and NT-proBNP, but not ADMA, endoglin and TIMP-1 levels, reflect impaired right ventricular function in patients with systemic sclerosis

Clinical Rheumatology

Volumn 33, Issue 1, 2014, Pages 83-89

  Ciurzynski, Michal ^a   Bienias, Piotr ^a   Irzyk, Katarzyna ^a   Kostrubiec, Maciej ^a   Bartoszewicz, Zbigniew ^a,b   Siwicka, Maria ^a   Stelmaszczyk Emmel, Anna ^a   Górska, Elzbieta ^a   Demkow, Urszula ^a   Pruszczyk, Piotr ^a  

^a MEDICAL UNIVERSITY OF WARSAW   (Poland)

^b MOSSAKOWSKI MEDICAL RESEARCH CENTRE   (Poland)

Author keywords

Biomarkers; Echocardiography; Pulmonary hypertension; Systemic sclerosis

Indexed keywords

AMINO TERMINAL PRO BRAIN NATRIURETIC PEPTIDE; ENDOGLIN; ENDOTHELIN 1; N(G),N(G) DIMETHYLARGININE; TISSUE INHIBITOR OF METALLOPROTEINASE 1; ARGININE; BIOLOGICAL MARKER; BRAIN NATRIURETIC PEPTIDE; CELL SURFACE RECEPTOR; COLLAGEN; DRUG DERIVATIVE; ENG PROTEIN, HUMAN; LEUKOCYTE ANTIGEN; N,N DIMETHYLARGININE; N,N-DIMETHYLARGININE; PEPTIDE FRAGMENT; PRO BRAIN NATRIURETIC PEPTIDE (1 76); PRO-BRAIN NATRIURETIC PEPTIDE (1-76); TIMP1 PROTEIN, HUMAN;

ADULT; ARTICLE; CARDIOGRAPH; CARDIOVASCULAR PARAMETERS; COLLAGEN METABOLISM; CONTROLLED STUDY; DISEASE DURATION; DOPPLER ECHOCARDIOGRAPHY; ENDOTHELIUM; FEMALE; HEART RIGHT VENTRICLE FAILURE; HEART RIGHT VENTRICLE OVERLOAD; HUMAN; INFERIOR CAVA VEIN; MAJOR CLINICAL STUDY; MALE; MIDDLE AGED; PRESSURE GRADIENT; PRIORITY JOURNAL; PROSPECTIVE STUDY; PROTEIN BLOOD LEVEL; SYSTEMIC SCLEROSIS; TRANSTHORACIC ECHOCARDIOGRAPHY; TRICUSPID VALVE REGURGITATION; ULTRASOUND TRANSDUCER; VEIN DIAMETER; AGED; BLOOD; CASE CONTROL STUDY; CHEMISTRY; ECHOCARDIOGRAPHY; FIBROSIS; HEART RIGHT VENTRICLE FUNCTION; LUNG DISEASE; PATHOLOGY; PATHOPHYSIOLOGY; VASCULAR ENDOTHELIUM;

ADULT; AGED; ANTIGENS, CD; ARGININE; BIOLOGICAL MARKERS; CASE-CONTROL STUDIES; COLLAGEN; ECHOCARDIOGRAPHY; ECHOCARDIOGRAPHY, DOPPLER; ENDOTHELIN-1; ENDOTHELIUM, VASCULAR; FEMALE; FIBROSIS; HUMANS; LUNG DISEASES; MALE; MIDDLE AGED; NATRIURETIC PEPTIDE, BRAIN; PEPTIDE FRAGMENTS; PROSPECTIVE STUDIES; RECEPTORS, CELL SURFACE; SCLERODERMA, SYSTEMIC; TISSUE INHIBITOR OF METALLOPROTEINASE-1; VENTRICULAR FUNCTION, RIGHT;

EID: 84897641100     PISSN: 07703198     EISSN: 14349949     Source Type: Journal    
DOI: 10.1007/s10067-013-2354-8     Document Type: Article

References (32)

1. Steen V (2005) Advancements in diagnosis of pulmonary arterial hypertension in scleroderma. Arthritis Rheum 52(12):3698-700
2. Zuhur F, Zuhur SS, Zuhur C, Musellim B, Ongen G (2012) Survival in progressive systemic sclerosis with pulmonary involvement: a single-center experience in Istanbul, Turkey. Rheumatol Int 32: 1655-61
3. ElhaiM,Meune C, Avouac J, Kahan A, Allanore Y (2012) Trends in mortality in patients with systemic sclerosis over 40 years: a systematic review and meta-analysis of cohort studies. Rheumatology (Oxford) 51(6):1017-26
4. Komocsi A,Vorobcsuk A, Faludi R, Pinter T, Lenkey Z,KoltoG et al (2012) The impact of cardiopulmonary manifestations on the mortality of SSc: a systematic review and meta-analysis of observational studies. Rheumatol (Oxford) 51(6):1027-36
5. Dimitroulas T, Giannakoulas G, Papadopoulou K, Sfetsios T, Karvounis H, Dimitroula H et al (2010) Left atrial volume and N-terminal pro-B type natriuretic peptide are associated with elevated pulmonary artery pressure in patients with systemic sclerosis. Clin Rheumatol 29(9):957-64
6. Galie N, HoeperMM, HumbertM, Torbicki A, Vachiery JL, Barbera JA et al (2009) Guidelines for the diagnosis and treatment of pulmonary hypertension: the Task Force for the Diagnosis and Treatment of Pulmonary Hypertension of the European Society of Cardiology (ESC) and the European Respiratory Society (ERS), endorsed by the International Society of Heart and Lung Transplantation (ISHLT). Eur Heart J 30(20):2493-537
7. Coral-Alvarado P, Quintana G, Garces MF, Cepeda LA, Caminos JE, Rondon F et al (2009) Potential biomarkers for detecting pulmonary arterial hypertension in patients with systemic sclerosis. Rheumatol Int 29(9):1017-24
8. EmdinM,Marini C, Passino C (2011) Right ventricular overload and cardiovascular neuroendocrine derangement in systemic sclerosis. Eur Heart J 6(suppl F):F68-F73
9. Mukerjee D, Yap LB, Holmes AM, Nair D, Ayrton P, Black CM et al (2003) Significance of plasma N-terminal pro-brain natriuretic peptide in patients with systemic sclerosis-related pulmonary arterial hypertension. Respir Med 97(11):1230-6
10. Dimitroulas T, Giannakoulas G, Sfetsios T, Karvounis H, Dimitroula H, Koliakos G et al (2008) Asymmetrical dimethylarginine in systemic sclerosis-related pulmonary arterial hypertension. Rheumatol (Oxford) 47(11):1682-5
11. Wipff J, Avouac J, Borderie D, Zerkak D, Lemarechal H, Kahan A et al (2008) Disturbed angiogenesis in systemic sclerosis: high levels of soluble endoglin. Rheumatol (Oxford) 47(7):972-5
12. Blaise S,Maas R, Trocme C, Kom GD, RoustitM, Carpentier PH et al (2009) Correlation of biomarkers of endothelium dysfunction and matrix remodeling in patients with systemic sclerosis. J Rheumatol 36(5):984-8
13. No authors listed (1980) Preliminary criteria for the classification of systemic sclerosis (scleroderma). Subcommittee for scleroderma criteria of the American Rheumatism Association Diagnostic and Therapeutic Criteria Committee. Arthritis Rheum 23(5):581-90
14. Valentini G, Bencivelli W, Bombardieri S, D'Angelo S, Della RA, Silman AJ et al (2003) European Scleroderma Study Group to define disease activity criteria for systemic sclerosis III. Assessment of the construct validity of the preliminary activity criteria. Ann Rheum Dis 62(9):901-3
15. Tei C, Dujardin KS, Hodge DO, Bailey KR, McGoon MD, Tajik AJ et al (1996) Doppler echocardiographic index for assessment of global right ventricular function. J Am Soc Echocardiogr 9(6):838-47
16. Feigenbaum H, Armstrong WF, Ryan T (2005) Feigenbaum's echocardiography, 6th edn. Lippincott, Williams&Wilkins, Philadelphia
17. ATS Committee on Proficiency Standards for Clinical Pulmonary Function Laboratories (2002) ATS statement: guidelines for the sixminute walk test. Am J Respir Crit Care Med 166(1):111-117
18. Chung L, Liu J, Parsons L, Hassoun PM, McGoon M, Badesch DB et al (2010) Characterization of connective tissue disease-associated pulmonary arterial hypertension from REVEAL: identifying systemic sclerosis as a unique phenotype. Chest 138(6):1383-94
19. Trad S, Amoura Z, Beigelman C, Haroche J, Costedoat N, le Boutin TH et al (2006) Pulmonary arterial hypertension is a major mortality factor in diffuse systemic sclerosis, independent of interstitial lung disease. Arthritis Rheum 54(1):184-91
20. Rudski LG, Lai WW, Afilalo J, Hua L, Handschumacher MD, Chandrasekaran K et al (2010) Guidelines for the echocardiographic assessment of the right heart in adults: a report from the American Society of Echocardiography endorsed by the European Association of Echocardiography, a registered branch of the European Society of Cardiology, and the Canadian Society of Echocardiography. J Am Soc Echocardiogr 23(7):685-713
21. Yeo TC, Dujardin KS, Tei C, Mahoney DW, McGoon MD, Seward JB (1998) Value of a Doppler-derived index combining systolic and diastolic time intervals in predicting outcome in primary pulmonary hypertension. Am J Cardiol 81(9):1157-61
22. Sebbag I, Rudski LG, Therrien J, Hirsch A, Langleben D (2001) Effect of chronic infusion of epoprostenol on echocardiographic right ventricular myocardial performance index and its relation to clinical outcome in patients with primary pulmonary hypertension. Am J Cardiol 88(9):1060-3
23. Hsiao SH, Lee CY, Chang SM, Lin SK, Liu CP (2006) Right heart function in scleroderma: insights from myocardial Doppler tissue imaging. J Am Soc Echocardiogr 19(5):507-14
24. Mathai SC, Sibley CT, Forfia PR, Mudd JO, Fisher MR, Tedford RJ et al (2011) Tricuspid annular plane systolic excursion is a robust outcome measure in systemic sclerosis-associated pulmonary arterial hypertension. J Rheumatol 38(11):2410-8
25. Miyamoto S, Nagaya N, Satoh T, Kyotani S, Sakamaki F, Fujita M et al (2000) Clinical correlates and prognostic significance of sixminute walk test in patients with primary pulmonary hypertension. Comparison with cardiopulmonary exercise testing. AmJ Respir Crit Care Med 161(2 Pt 1):487-92
26. CiurzynskiM, Bienias P, Lichodziejewska B, Kurnicka K, Szewczyk A, Glinska-Wielochowska M et al (2008) Non-invasive diagnostic and functional evaluation of cardiac involvement in patients with systemic sclerosis. Clin Rheumatol 27(8):991-7
27. Huez S, Roufosse F, Vachiery JL, Pavelescu A, Derumeaux G, Wautrecht JC et al (2007) Isolated right ventricular dysfunction in systemic sclerosis: latent pulmonary hypertension? Eur Respir J 30(5):928-36
28. Williams MH, Handler CE, Akram R, Smith CJ, Das C, Smee J et al (2006) Role of N-terminal brain natriuretic peptide (N-TproBNP) in scleroderma- associated pulmonary arterial hypertension. Eur Heart J 27(12):1485-94
29. Coghlan JG, Denton CP, Grunig E, Bonderman D, Distler O, Khanna D, et al (2013) Evidence-based detection of pulmonary arterial hypertension in systemic sclerosis: the DETECT study. Ann Rheum Dis (in press)
30. Oravec RM, Bredemeier M, Laurino CC, Pinotti AF, Rohde LE, Brenol JC et al (2010) NT-proBNP levels in systemic sclerosis: association with clinical and laboratory abnormalities. Clin Biochem 43(9):745-9
31. Coral-Alvarado PX, Garces MF, Caminos JE, Iglesias-Gamarra A, Restrepo JF, Quintana G (2010) Serum endoglin levels in patients suffering from systemic sclerosis and elevated systolic pulmonary arterial pressure. Int J Rheumatol. doi:10.1155/2010/ 969383
32. Young-Min SA, Beeton C, Laughton R, Plumpton T, Bartram S, Murphy G et al (2001) Serum TIMP-1, TIMP-2, and MMP-1 in patients with systemic sclerosis, primary Raynaud's phenomenon, and in normal controls. Ann Rheum Dis 60(9):846-51