메뉴 건너뛰기




Volumn 2, Issue 3, 2002, Pages 163-179

Mechanism of leflunomide-induced proliferation of mitochondria in mammalian cells

Author keywords

Acetylated tubulin; Culture cells; Dihydroorotate dehydrogenase; Flow cytometry; Leflunomide; Microtubules; Mitochondrial biogenesis; Oxidative stress

Indexed keywords


EID: 84897585077     PISSN: 15677249     EISSN: 18728278     Source Type: Journal    
DOI: 10.1016/S1567-7249(02)00045-4     Document Type: Article
Times cited : (30)

References (81)
  • 1
    • 0023664272 scopus 로고
    • Genistein, a specific inhibitor of tyrosin-specific protein kinases
    • Akiyama, T., Ishida, J., Nakagawa, S., et al., 1987. Genistein, a specific inhibitor of tyrosin-specific protein kinases. J. Biol. Chem. 262, 5592-5595
    • (1987) J. Biol. Chem. , vol.262 , pp. 5592-5595
    • Akiyama, T.1    Ishida, J.2    Nakagawa, S.3
  • 2
    • 0039064824 scopus 로고
    • Mitochondria are associated with microtubules and not with intermediate filaments in cultured fibroblasts
    • Ball, E.H., Singer, S.J., 1982. Mitochondria are associated with microtubules and not with intermediate filaments in cultured fibroblasts. Proc. Natl Acad. Sci. USA 79, 123-126
    • (1982) Proc. Natl Acad. Sci. USA , vol.79 , pp. 123-126
    • Ball, E.H.1    Singer, S.J.2
  • 3
    • 0025980747 scopus 로고
    • Leflunomide (HWA 486), a novel immunomodulating compound for the treatment of autoimmune disorders and reactions leading to transplantation reaction
    • Bartlett, R.R., Dimitrijevic, M., Matter, T., et al., 1991. Leflunomide (HWA 486), a novel immunomodulating compound for the treatment of autoimmune disorders and reactions leading to transplantation reaction. Agents Actions 32, 10-21
    • (1991) Agents Actions , vol.32 , pp. 10-21
    • Bartlett, R.R.1    Dimitrijevic, M.2    Matter, T.3
  • 4
    • 0029852104 scopus 로고    scopus 로고
    • Leflunomide, an immunostoring drug for the therapy of autoimmune disorders, especially rheumatoid arthritis
    • Bartlett, R.R., Brendel, S., Zielinski, T., Schorlemmer, H.-U., 1996. Leflunomide, an immunostoring drug for the therapy of autoimmune disorders, especially rheumatoid arthritis. Transpl. Proc. 28, 3074-3078
    • (1996) Transpl. Proc. , vol.28 , pp. 3074-3078
    • Bartlett, R.R.1    Brendel, S.2    Zielinski, T.3    Schorlemmer, H.-U.4
  • 5
    • 0024951774 scopus 로고
    • Compared flow cytometric analysis of mito-chondria using 10-n-nonyl acridine orange and rhodamine 123
    • Benel, L., Ronot, X., Ronot, X., Mounolou, J.C., Gaudemer, F., Adolphe, M., 1989. Compared flow cytometric analysis of mito-chondria using 10-n-nonyl acridine orange and rhodamine 123. Basic Appl. Histochem. 33, 71-80
    • (1989) Basic Appl. Histochem. , vol.33 , pp. 71-80
    • Benel, L.1    Ronot, X.2    Ronot, X.3    Mounolou, J.C.4    Gaudemer, F.5    Adolphe, M.6
  • 6
    • 0025036216 scopus 로고
    • Behavior of mitochondria in the living cell
    • Bereiter-Hahn, J., 1990. Behavior of mitochondria in the living cell. Int. Rev. Cytol. 122, 1-63
    • (1990) Int. Rev. Cytol. , vol.122 , pp. 1-63
    • Bereiter-Hahn, J.1
  • 7
    • 0014682211 scopus 로고
    • Replication of nuclear satellite and mitochondrial DNA in the mitotic cycle of Physarium
    • Braun, R., Evans, T.E., 1969. Replication of nuclear satellite and mitochondrial DNA in the mitotic cycle of Physarium. Biochim. Biophys. Acta 182, 511-522
    • (1969) Biochim. Biophys. Acta , vol.182 , pp. 511-522
    • Braun, R.1    Evans, T.E.2
  • 8
    • 0031869931 scopus 로고    scopus 로고
    • Distinct alterations in mitochondrial mass and function characterize different modes of apoptosis
    • Camilleri-Broet, S., Vanderwerff, H., Caldwell, E., Hockenbery, D., 1998. Distinct alterations in mitochondrial mass and function characterize different modes of apoptosis. Exp. Cell Res. 239, 277-292
    • (1998) Exp. Cell Res. , vol.239 , pp. 277-292
    • Camilleri-Broet, S.1    Vanderwerff, H.2    Caldwell, E.3    Hockenbery, D.4
  • 10
    • 0029670034 scopus 로고    scopus 로고
    • p185erbB2 binds to GRP94 in vivo Dissociation of the p185erbB2/GRP94 heterocomplex by benzoquinone ansamycins precedes depletion of p185erbB2
    • Chavany, C., Mimnaugh, E., Miller, P., et al., 1996. p185erbB2 binds to GRP94 in vivo. Dissociation of the p185erbB2/GRP94 heterocomplex by benzoquinone ansamycins precedes depletion of p185erbB2. J. Biol. Chem. 271, 4974-4977
    • (1996) J. Biol. Chem. , vol.271 , pp. 4974-4977
    • Chavany, C.1    Mimnaugh, E.2    Miller, P.3
  • 11
    • 0017134372 scopus 로고
    • The cellular location of dihydroorotate dehydrogenase: relation to de novo biosynthesis of pyrimidines
    • Chen, J.J., Jones, M.E., 1976. The cellular location of dihydroorotate dehydrogenase: relation to de novo biosynthesis of pyrimidines. Arch. Biochem. Biophys. 176, 82-90
    • (1976) Arch. Biochem. Biophys. , vol.176 , pp. 82-90
    • Chen, J.J.1    Jones, M.E.2
  • 12
    • 0024483266 scopus 로고
    • Fluorescent labeling of mitochondria
    • Chen, L.B., 1989. Fluorescent labeling of mitochondria. Methods Cell Biol. 29, 103-123
    • (1989) Methods Cell Biol , vol.29 , pp. 103-123
    • Chen, L.B.1
  • 13
    • 0028985102 scopus 로고
    • The immunosuppressant leflunomide inhibits lymphocyte progression through cell cycle by a novel mechanism
    • Cherwinski, H.M., McCarley, D., Schatzman, R., Devens, B., Ransom, J.T., 1995a. The immunosuppressant leflunomide inhibits lymphocyte progression through cell cycle by a novel mechanism. J. Pharmacol. Exp. Ther. 272, 460-468
    • (1995) J. Pharmacol. Exp. Ther. , vol.272 , pp. 460-468
    • Cherwinski, H.M.1    McCarley, D.2    Schatzman, R.3    Devens, B.4    Ransom, J.T.5
  • 14
    • 0029591467 scopus 로고
    • The immunosuppressant leflunomide inhibits lymphocyte proliferation by inhibiting pyrimidine biosynthesis
    • Cherwinski, H.M., Cohn, R.G., Cheung, P., et al., 1995b. The immunosuppressant leflunomide inhibits lymphocyte proliferation by inhibiting pyrimidine biosynthesis. J. Pharmacol. Exp. Ther. 275, 1043-1049
    • (1995) J. Pharmacol. Exp. Ther. , vol.275 , pp. 1043-1049
    • Cherwinski, H.M.1    Cohn, R.G.2    Cheung, P.3
  • 15
    • 0027279125 scopus 로고
    • Leflunomide, a novel immunosuppressive agent The mechanism of inhibition of T cell proliferation
    • Chong, A.S., Finnegan, A., Jiang, X., et al., 1993. Leflunomide, a novel immunosuppressive agent. The mechanism of inhibition of T cell proliferation. Transplantation 55, 1361-1366
    • (1993) Transplantation , vol.55 , pp. 1361-1366
    • Chong, A.S.1    Finnegan, A.2    Jiang, X.3
  • 16
    • 0027931215 scopus 로고
    • Mitochondrial modifications during rat thymocyte apoptosis: a study at the single cell level
    • Cossarizza, A., Kalashnikova, G., Grassilli, E., et al., 1994. Mitochondrial modifications during rat thymocyte apoptosis: a study at the single cell level. Exp. Cell Res. 214, 323-330
    • (1994) Exp. Cell Res. , vol.214 , pp. 323-330
    • Cossarizza, A.1    Kalashnikova, G.2    Grassilli, E.3
  • 17
    • 0014942251 scopus 로고
    • Evidence of mitochondrial synchrony in synchronous cell cultures of yeast
    • Cottrell, S.F., Avers, C.J., 1970. Evidence of mitochondrial synchrony in synchronous cell cultures of yeast. Biochem. Biophys. Res. Commun. 38, 973-980
    • (1970) Biochem. Biophys. Res. Commun. , vol.38 , pp. 973-980
    • Cottrell, S.F.1    Avers, C.J.2
  • 18
    • 0029069122 scopus 로고
    • Early features of zidobudine-associated myopathy: histopathological findings and clinical correlations
    • Cupler, E.J., Danon, M.J., Jay, C., Hench, K., Rapka, M., Dalakos, M.C., 1995. Early features of zidobudine-associated myopathy: histopathological findings and clinical correlations. Acta Neuropathol. 90, 1-6
    • (1995) Acta Neuropathol , vol.90 , pp. 1-6
    • Cupler, E.J.1    Danon, M.J.2    Jay, C.3    Hench, K.4    Rapka, M.5    Dalakos, M.C.6
  • 19
    • 0029803242 scopus 로고    scopus 로고
    • In situ localization of mitochondrial DNA replication in intact mammalian cells
    • Davis, A.F., Clayton, D.A., 1996. In situ localization of mitochondrial DNA replication in intact mammalian cells. J. Cell Biol. 135, 883-893
    • (1996) J. Cell Biol. , vol.135 , pp. 883-893
    • Davis, A.F.1    Clayton, D.A.2
  • 20
    • 0020384216 scopus 로고
    • A stable propidium iodide staining procedure for flow cytometry
    • Deitch, A.D., Law, H., deVere White, R., 1982. A stable propidium iodide staining procedure for flow cytometry. J. Histochem. Cytochem. 30, 967-972
    • (1982) J. Histochem. Cytochem. , vol.30 , pp. 967-972
    • Deitch, A.D.1    Law, H.2    deVere White, R.3
  • 21
    • 0027765526 scopus 로고
    • Actin structure and function: roles in mitochondrial organization and morphogenesis in budding yeast and identification of the phalloidinbinding site
    • Drubin, D.G., Jones, H.D., Wertman, K.F., 1993. Actin structure and function: roles in mitochondrial organization and morphogenesis in budding yeast and identification of the phalloidinbinding site. Mol. Biol. Cell 4, 1277-1294
    • (1993) Mol. Biol. Cell , vol.4 , pp. 1277-1294
    • Drubin, D.G.1    Jones, H.D.2    Wertman, K.F.3
  • 22
    • 0014024710 scopus 로고
    • Synthesis of a cytoplasmic DNA during the G2 interphase of Physarum polycephalum
    • Evans, T.E., 1966. Synthesis of a cytoplasmic DNA during the G2 interphase of Physarum polycephalum. Biochem. Biophys. Res. Commun. 22, 678-683
    • (1966) Biochem. Biophys. Res. Commun. , vol.22 , pp. 678-683
    • Evans, T.E.1
  • 23
    • 0029585361 scopus 로고
    • Importance of ribonucleotide availability to proliferating T-lymphocytes from healthy humans Disproportionate expansion of pyrimidine pools and contrasting effects of de novo synthesis inhibitors
    • Fairbanks, L.D., Bofill, M., Ruckermann, K., Simmonds, H.A., 1995. Importance of ribonucleotide availability to proliferating T-lymphocytes from healthy humans. Disproportionate expansion of pyrimidine pools and contrasting effects of de novo synthesis inhibitors. J. Biol. Chem. 270, 29682-29689
    • (1995) J. Biol. Chem. , vol.270 , pp. 29682-29689
    • Fairbanks, L.D.1    Bofill, M.2    Ruckermann, K.3    Simmonds, H.A.4
  • 24
    • 0024416087 scopus 로고
    • Pervanadate [peroxide(s) of vanadate] mimics insulin action in rat adipocytes via activation of the insulin receptor tyrosine kinase
    • Fantus, I.G., Kadota, S., Deragon, G., Foster, B., Posner, B.I., 1989. Pervanadate [peroxide(s) of vanadate] mimics insulin action in rat adipocytes via activation of the insulin receptor tyrosine kinase. Biochemistry 28, 8864-8871
    • (1989) Biochemistry , vol.28 , pp. 8864-8871
    • Fantus, I.G.1    Kadota, S.2    Deragon, G.3    Foster, B.4    Posner, B.I.5
  • 25
    • 0017293045 scopus 로고
    • Dihydrogenase-dependent superoxide production in rat brain and liver
    • Forman, H.J., Kennedy, J., 1976. Dihydrogenase-dependent superoxide production in rat brain and liver. Arch. Biochem. Biophys. 173, 219-224
    • (1976) Arch. Biochem. Biophys. , vol.173 , pp. 219-224
    • Forman, H.J.1    Kennedy, J.2
  • 26
    • 0018069247 scopus 로고
    • Mammalian dihydroorotate dehydrogenase: physical and catalytic properties of the primary enzyme
    • Forman, H.J., Kennedy, J., 1978. Mammalian dihydroorotate dehydrogenase: physical and catalytic properties of the primary enzyme. Arch. Biochem Biophys. 191, 23-31
    • (1978) Arch. Biochem Biophys. , vol.191 , pp. 23-31
    • Forman, H.J.1    Kennedy, J.2
  • 27
    • 0032804664 scopus 로고    scopus 로고
    • Mechanism of action of leflunomide in rheumatoid arthritis
    • Fox, R.I., Hermann, M.L., Frangou, C.G., et al., 1999. Mechanism of action of leflunomide in rheumatoid arthritis. Clin. Immunol. 93, 198-208
    • (1999) Clin. Immunol. , vol.93 , pp. 198-208
    • Fox, R.I.1    Hermann, M.L.2    Frangou, C.G.3
  • 28
  • 29
    • 0025193521 scopus 로고
    • 2 and vanadate stimulate protein tyrosine phosphorylation in intact cells
    • 2 and vanadate stimulate protein tyrosine phosphorylation in intact cells. J. Biol. Chem. 26, 2896-2902
    • (1990) J. Biol. Chem. , vol.26 , pp. 2896-2902
    • Heffetz, D.1    Buskin, I.2    Dror, R.3    Zick, Y.4
  • 30
    • 0017691122 scopus 로고
    • Intracellular distribution of mechanochemical proteins in cultured fibroblasts
    • Heggenes, M.H., Wang, K., Singer, S.J., 1977. Intracellular distribution of mechanochemical proteins in cultured fibroblasts. Proc. Natl Acad. Sci. USA 74, 3883-3887
    • (1977) Proc. Natl Acad. Sci. USA , vol.74 , pp. 3883-3887
    • Heggenes, M.H.1    Wang, K.2    Singer, S.J.3
  • 31
    • 0008688565 scopus 로고
    • Association of mitochondria with mictotubules in cultured cells
    • Heggenes, M.H., Simon, M., Singer, S.J., 1978. Association of mitochondria with mictotubules in cultured cells. Proc. Natl Acad. Sci. USA 75, 3863-3866
    • (1978) Proc. Natl Acad. Sci. USA , vol.75 , pp. 3863-3866
    • Heggenes, M.H.1    Simon, M.2    Singer, S.J.3
  • 32
    • 0023009615 scopus 로고
    • Purification and properties of the bovine liver mitochondrial dihydroorotate dehydrogenase
    • Hines, V., Keys, L.D., Johnson, M., 1986. Purification and properties of the bovine liver mitochondrial dihydroorotate dehydrogenase. J. Biol. Chem. 261, 11386-11392
    • (1986) J. Biol. Chem. , vol.261 , pp. 11386-11392
    • Hines, V.1    Keys, L.D.2    Johnson, M.3
  • 33
    • 0014468131 scopus 로고
    • Minor components of the DNA of Physarum polycephalum Cellular location and metabolism
    • Holt, C.E., Gurney, E.G., 1969. Minor components of the DNA of Physarum polycephalum. Cellular location and metabolism. J. Cell Biol. 40, 484-496
    • (1969) J. Cell Biol. , vol.40 , pp. 484-496
    • Holt, C.E.1    Gurney, E.G.2
  • 34
    • 0032951918 scopus 로고    scopus 로고
    • Free radical-induced megamitochondria formation and apoptosis
    • Karbowski, M., Kurono, C., Wozniak, M., et al., 1999a. Free radical-induced megamitochondria formation and apoptosis. Free Radic. Biol. Med. 26, 396-409
    • (1999) Free Radic. Biol. Med. , vol.26 , pp. 396-409
    • Karbowski, M.1    Kurono, C.2    Wozniak, M.3
  • 35
    • 0032992922 scopus 로고    scopus 로고
    • Cychloheximide and 4-OH-TEMPO suppress chloramphenicol-induced apoptosis in RL-34 cells via the suppression of the formation of megamitochondria
    • Karbowski,M., Kurono, C., Wozniak, M., et al., 1999b. Cychloheximide and 4-OH-TEMPO suppress chloramphenicol-induced apoptosis in RL-34 cells via the suppression of the formation of megamitochondria. Biochim. Biophys. Acta 1449, 25-40
    • (1999) Biochim. Biophys. Acta , vol.1449 , pp. 25-40
    • Karbowski, M.1    Kurono, C.2    Wozniak, M.3
  • 36
    • 0035127509 scopus 로고    scopus 로고
    • Opposite effects of micritubule-stabilizing and microtubule-destabilizing drugs on biogenesis of mitochondria in mammalian cells
    • Karbowski, M., Spodnik, J.H., Teranishi, M., et al., 2001. Opposite effects of micritubule-stabilizing and microtubule-destabilizing drugs on biogenesis of mitochondria in mammalian cells. J. Cell Sci. 114, 281-291
    • (2001) J. Cell Sci. , vol.114 , pp. 281-291
    • Karbowski, M.1    Spodnik, J.H.2    Teranishi, M.3
  • 37
    • 0016695005 scopus 로고
    • Mitochondrial proliferation in synchronized cells of Tetrahymena pyriformis A morphometric study by electron microscopy on the biogenesis of mitochondria during cell cycle
    • Kolb-Bachofen, V., Vogell, W., 1975. Mitochondrial proliferation in synchronized cells of Tetrahymena pyriformis. A morphometric study by electron microscopy on the biogenesis of mitochondria during cell cycle. Exp. cell Res. 94, 95-105
    • (1975) Exp. cell Res. , vol.94 , pp. 95-105
    • Kolb-Bachofen, V.1    Vogell, W.2
  • 38
    • 0029922167 scopus 로고    scopus 로고
    • Isolation of human cell lines lacking mitochondrial DNA
    • King, M.P., Attardi, G., 1996. Isolation of human cell lines lacking mitochondrial DNA. Methods Enzymol. 264, 304-313
    • (1996) Methods Enzymol , vol.264 , pp. 304-313
    • King, M.P.1    Attardi, G.2
  • 39
    • 0025990299 scopus 로고
    • Malarial dihydroorotate dehydrogenase mediates superoxide radical production
    • Krungkrai, J., 1991. Malarial dihydroorotate dehydrogenase mediates superoxide radical production. Biochem. Int. 24, 833-839
    • (1991) Biochem. Int. , vol.24 , pp. 833-839
    • Krungkrai, J.1
  • 40
    • 0028048692 scopus 로고
    • Yeast mitochondria contain ATP-sensitive, reversible actin-binding activity
    • Lazzarino, D., Boldogh, I., Smith, M.G., Rosand, J., Pon, L.A., 1994. Yeast mitochondria contain ATP-sensitive, reversible actin-binding activity. Mol. Biol. Cell 5, 807-818
    • (1994) Mol. Biol. Cell , vol.5 , pp. 807-818
    • Lazzarino, D.1    Boldogh, I.2    Smith, M.G.3    Rosand, J.4    Pon, L.A.5
  • 41
    • 0034214103 scopus 로고    scopus 로고
    • Increase of mitochondrial DNA in response to oxidative stress in human cells
    • Lee, H.C., Yin, P.-H., Lu, C.-Y., Chi, C.-W., Wei, Y.-H., 2000. Increase of mitochondrial DNA in response to oxidative stress in human cells. Biochem. J. 348, 425-432
    • (2000) Biochem. J. , vol.348 , pp. 425-432
    • Lee, H.C.1    Yin, P.-H.2    Lu, C.-Y.3    Chi, C.-W.4    Wei, Y.-H.5
  • 42
    • 0025117489 scopus 로고
    • Use of Nonyl Acridine Orange and Rhodamine 123 to follow biosynthesis and functional assembly of mitochondrial membrane during L1210 cell cycle
    • Leprat, P., Ratinaud, M.H., Maftah, A., Petit, J.M., Julien, R., 1990. Use of Nonyl Acridine Orange and Rhodamine 123 to follow biosynthesis and functional assembly of mitochondrial membrane during L1210 cell cycle. Exp. Cell Res. 186, 130-137
    • (1990) Exp. Cell Res. , vol.186 , pp. 130-137
    • Leprat, P.1    Ratinaud, M.H.2    Maftah, A.3    Petit, J.M.4    Julien, R.5
  • 43
    • 0028107194 scopus 로고
    • Interactions between brain mitochondria and cytoskeleton: evidence for specialized outer membrane domains involved in the association of cytoskeleton-associated proteins to mitochondria in situ and in vivo
    • Leterrier, J.F., Rusakov, D.A., Nelson, B.D., Linden, M., 1994. Interactions between brain mitochondria and cytoskeleton: evidence for specialized outer membrane domains involved in the association of cytoskeleton-associated proteins to mitochondria in situ and in vivo. Microsc. Res. Technique 27, 233- 236
    • (1994) Microsc. Res. Technique , vol.27 , pp. 233-236
    • Leterrier, J.F.1    Rusakov, D.A.2    Nelson, B.D.3    Linden, M.4
  • 44
    • 0027968951 scopus 로고
    • Evidence for involvement of tyrosine phosphorylation in taxol-induced apoptosis in a human ovarian tumor cell line
    • Liu, Y., Bhalla, K., Hill, C., Priest, D.G., 1994. Evidence for involvement of tyrosine phosphorylation in taxol-induced apoptosis in a human ovarian tumor cell line. Biochem. Pharmacol. 48, 1265-1272
    • (1994) Biochem. Pharmacol. , vol.48 , pp. 1265-1272
    • Liu, Y.1    Bhalla, K.2    Hill, C.3    Priest, D.G.4
  • 45
    • 0028792355 scopus 로고
    • Safety and effectiveness of leflunomide in the treatment of patients with active rheumatoid arthritis
    • Madenovic, V., Domljian, Z., Rozman, B., et al., 1995. Safety and effectiveness of leflunomide in the treatment of patients with active rheumatoid arthritis. Arthritis Rheum. 38, 1595-1603
    • (1995) Arthritis Rheum , vol.38 , pp. 1595-1603
    • Madenovic, V.1    Domljian, Z.2    Rozman, B.3
  • 46
    • 0024447105 scopus 로고
    • 10- N nonyl-acridine orange: a fluorescent probe which stains mitochondria independently of their energetic state
    • Maftah, A., Petit, J.M., Ratinaud, M.H., Julien, R., 1989. 10-N nonyl-acridine orange: a fluorescent probe which stains mitochondria independently of their energetic state. Biochem. Biophys. Res. Commun. 164, 185-190
    • (1989) Biochem. Biophys. Res. Commun. , vol.164 , pp. 185-190
    • Maftah, A.1    Petit, J.M.2    Ratinaud, M.H.3    Julien, R.4
  • 47
    • 0030792850 scopus 로고    scopus 로고
    • Mitochondrial proliferation and paradoxical membrane depolarization during terminal differentiation and apoptosis in human colon carcinoma cell line
    • Mancini, M., Anderson, B.O., Caldwell, E., Sedghinasab, M., Paty, P.B., Hockenbery, D.M., 1997. Mitochondrial proliferation and paradoxical membrane depolarization during terminal differentiation and apoptosis in human colon carcinoma cell line. J. Cell Biol. 138, 449-469
    • (1997) J. Cell Biol. , vol.138 , pp. 449-469
    • Mancini, M.1    Anderson, B.O.2    Caldwell, E.3    Sedghinasab, M.4    Paty, P.B.5    Hockenbery, D.M.6
  • 48
    • 0026670898 scopus 로고
    • Taxol increases steady-state levels of lipopolysaccharide-inducible genes and protein-tyrosine phosporylation in murine macrophages
    • Manthey, C.L., Brandes, M.E., Perera, P.Y., Vogel, S.N., 1992. Taxol increases steady-state levels of lipopolysaccharide-inducible genes and protein-tyrosine phosporylation in murine macrophages. J. Immunol. 149, 2459-2465
    • (1992) J. Immunol. , vol.149 , pp. 2459-2465
    • Manthey, C.L.1    Brandes, M.E.2    Perera, P.Y.3    Vogel, S.N.4
  • 49
    • 0028861992 scopus 로고
    • Axonal transport of mitochondria along micritubules and actin in living vertebrate neurons
    • Morris, R.J., Hollenbeck, P.J., 1995. Axonal transport of mitochondria along micritubules and actin in living vertebrate neurons. J. Cell Biol. 131, 1315-1326
    • (1995) J. Cell Biol. , vol.131 , pp. 1315-1326
    • Morris, R.J.1    Hollenbeck, P.J.2
  • 50
    • 0020469904 scopus 로고
    • Putative association of mitochondria with asubpopulation of intermediate-sized filaments in cultured human skin fibroblasts
    • Mose Larsen, P., Bravo, R., Fey, S.J., Small, J.V., Celis, J.E., 1982. Putative association of mitochondria with asubpopulation of intermediate-sized filaments in cultured human skin fibroblasts. Cell 31, 681-692
    • (1982) Cell , vol.31 , pp. 681-692
    • Mose Larsen, P.1    Bravo, R.2    Fey, S.J.3    Small, J.V.4    Celis, J.E.5
  • 52
    • 0028641560 scopus 로고
    • KIF1B, a novel microtubule plus end-directed monomeric motor protein for transport of mitochondria
    • Nangaku, M., Sato-Yoshitake, R., Okada, Y., et al., 1994. KIF1B, a novel microtubule plus end-directed monomeric motor protein for transport of mitochondria. Cell 79, 1209-1220
    • (1994) Cell , vol.79 , pp. 1209-1220
    • Nangaku, M.1    Sato-Yoshitake, R.2    Okada, Y.3
  • 53
    • 0025995324 scopus 로고
    • Long-term potentiation in the hippocampus is blocked by tyrosine kinase inhibitors
    • O'Dell, T.J., Kandel, E.R., Grant, S.G., 1991. Long-term potentiation in the hippocampus is blocked by tyrosine kinase inhibitors. Nature 353, 558-560
    • (1991) Nature , vol.353 , pp. 558-560
    • O'Dell, T.J.1    Kandel, E.R.2    Grant, S.G.3
  • 54
    • 0027179465 scopus 로고
    • Genistein inhibits tumour cell growth in vitro but enhances mitochondrial reduction of tetrazorium salts: a further pitfall in the use of the MTT assay for evaluating cell growth and survival
    • Pagliacci, M.C., Spinozzi, F., Migliorati, G., et al., 1993. Genistein inhibits tumour cell growth in vitro but enhances mitochondrial reduction of tetrazorium salts: a further pitfall in the use of the MTT assay for evaluating cell growth and survival. Eur. J. Cancer 29A, 1573-1577
    • (1993) Eur. J. Cancer , vol.29 A , pp. 1573-1577
    • Pagliacci, M.C.1    Spinozzi, F.2    Migliorati, G.3
  • 55
    • 3242842321 scopus 로고    scopus 로고
    • Analysis of mitochondrial morphology and function with novel fixable fluorescent stains
    • Poot, M., Zhang, Y.-Z., Kramer, J.A., et al., 1996. Analysis of mitochondrial morphology and function with novel fixable fluorescent stains. J. Histochem. Cytochem. 44, 1363-1372
    • (1996) J. Histochem. Cytochem. , vol.44 , pp. 1363-1372
    • Poot, M.1    Zhang, Y.-Z.2    Kramer, J.A.3
  • 56
    • 0028866042 scopus 로고
    • Changes of mitochondrial mass in the hemopoietic stem cell line FDCP-mix after treatment with etoposide: a correlative study by multiparameter flow cytometry and confocal and electron microscopy
    • Reipert, S., Berry, J., Hughes, M.F., Hickman, J.A., Allen, T.D., 1995. Changes of mitochondrial mass in the hemopoietic stem cell line FDCP-mix after treatment with etoposide: a correlative study by multiparameter flow cytometry and confocal and electron microscopy. Exp. Cell Res. 221, 281-288
    • (1995) Exp. Cell Res. , vol.221 , pp. 281-288
    • Reipert, S.1    Berry, J.2    Hughes, M.F.3    Hickman, J.A.4    Allen, T.D.5
  • 57
    • 0021135281 scopus 로고
    • Association of elements of the Golgi apparatus with microtubules
    • Rogalski, A.A., Singer, S.J., 1984. Association of elements of the Golgi apparatus with microtubules. J. Cell Biol. 99, 1092-1100
    • (1984) J. Cell Biol. , vol.99 , pp. 1092-1100
    • Rogalski, A.A.1    Singer, S.J.2
  • 58
    • 0029811256 scopus 로고    scopus 로고
    • Mechanism of action of leflunomide: in vivo uridine administration reverses its inhibition of lymphoid proliferation
    • Silva, H.T., Cao, W., Shorthouse, R., Morris, R.E., 1996. Mechanism of action of leflunomide: in vivo uridine administration reverses its inhibition of lymphoid proliferation. Transpl. Proc. 28, 1996-3084
    • (1996) Transpl. Proc. , vol.28 , pp. 1996-3084
    • Silva, H.T.1    Cao, W.2    Shorthouse, R.3    Morris, R.E.4
  • 59
    • 0029078227 scopus 로고
    • Actin-dependent mitochondrial motility in mitotic yeast and cell-free systems: identification of a motor activity on the mitochondrial surface
    • Simon, V.R., Swayne, T.C., Pon, L.A., 1995. Actin-dependent mitochondrial motility in mitotic yeast and cell-free systems: identification of a motor activity on the mitochondrial surface. J. Cell Biol. 130, 345-354
    • (1995) J. Cell Biol. , vol.130 , pp. 345-354
    • Simon, V.R.1    Swayne, T.C.2    Pon, L.A.3
  • 60
    • 0014307096 scopus 로고
    • The replication of mitochondrial DNA during the cell cycle in Saccharomyces lactis
    • Smith, D., Tauro, P., Schweizer, E., Halvorsen, H.O., 1968. The replication of mitochondrial DNA during the cell cycle in Saccharomyces lactis. Proc. Natl Acad. Sci. USA 60, 936-942
    • (1968) Proc. Natl Acad. Sci. USA , vol.60 , pp. 936-942
    • Smith, D.1    Tauro, P.2    Schweizer, E.3    Halvorsen, H.O.4
  • 62
    • 0025082774 scopus 로고
    • Immunocytochemical identification of cytoskeletal linkages to smooth muscle cell nuclei and mitochondria
    • Stromer, M.H., Bendayan, M., 1990. Immunocytochemical identification of cytoskeletal linkages to smooth muscle cell nuclei and mitochondria. Cell Motil. Cytoskelet. 17, 11-18
    • (1990) Cell Motil. Cytoskelet. , vol.17 , pp. 11-18
    • Stromer, M.H.1    Bendayan, M.2
  • 63
    • 0020760101 scopus 로고
    • Effect of microtubules and intermediate filaments on mitochondrial distribution
    • Summerhayes, I.C., Wong, D., Chen, L.B., 1983. Effect of microtubules and intermediate filaments on mitochondrial distribution. J. Cell Sci. 61, 87-105
    • (1983) J. Cell Sci. , vol.61 , pp. 87-105
    • Summerhayes, I.C.1    Wong, D.2    Chen, L.B.3
  • 65
    • 0033137350 scopus 로고    scopus 로고
    • Effects of coenzyme Q10 on changes in the membrane potential and rate of generation of reactive oxygen species in hydrazine- and chloramphenicol-treated rat liver mitochondria
    • Teranishi, M., Karbowski, M., Kurono, C., et al., 1999. Effects of coenzyme Q10 on changes in the membrane potential and rate of generation of reactive oxygen species in hydrazine- and chloramphenicol-treated rat liver mitochondria. Arch. Biochem. Biophys. 366, 157-167
    • (1999) Arch. Biochem. Biophys. , vol.366 , pp. 157-167
    • Teranishi, M.1    Karbowski, M.2    Kurono, C.3
  • 66
    • 0027987340 scopus 로고
    • Interaction among endoplasmic reticulum, microtubules, and retrograde movements of the cell surface
    • Terasaki, M., Reese, T.S., 1994. Interaction among endoplasmic reticulum, microtubules, and retrograde movements of the cell surface. Cell Motil. Cytoskelet. 29, 291-300
    • (1994) Cell Motil. Cytoskelet. , vol.29 , pp. 291-300
    • Terasaki, M.1    Reese, T.S.2
  • 67
    • 0033080404 scopus 로고    scopus 로고
    • Microtubules and the organization of the Golgi complex
    • Thyberg, J., Moskalewski, S., 1999. Microtubules and the organization of the Golgi complex. Exp. Cell Res. 246, 263-279
    • (1999) Exp. Cell Res. , vol.246 , pp. 263-279
    • Thyberg, J.1    Moskalewski, S.2
  • 68
    • 0021910658 scopus 로고
    • Movement of organelles along filaments dissociated from the axoplasm of the squid giant axon
    • Vale, R.D., Schnapp, B.J., Reese, T.S., Sheetz, M.P., 1995. Movement of organelles along filaments dissociated from the axoplasm of the squid giant axon. Cell 40, 449-454
    • (1995) Cell , vol.40 , pp. 449-454
    • Vale, R.D.1    Schnapp, B.J.2    Reese, T.S.3    Sheetz, M.P.4
  • 70
    • 0027258955 scopus 로고
    • MAP kinase becomes stably activated at metaphase and is associated with microtubule-organizing centers during meiotic maturation of mouse oocytes
    • Verhac, M.H., de Pennart, H., Maro, B., Cobb, M.H., Clarke, H.J., 1993. MAP kinase becomes stably activated at metaphase and is associated with microtubule-organizing centers during meiotic maturation of mouse oocytes. Dev. Biol. 158, 330-340
    • (1993) Dev. Biol. , vol.158 , pp. 330-340
    • Verhac, M.H.1    de Pennart, H.2    Maro, B.3    Cobb, M.H.4    Clarke, H.J.5
  • 71
    • 0021258307 scopus 로고
    • Mechanism of hepatic megamitochondria formation by ammonia derivatives Correlation between structures of chemicals and their ability to induce the formation of megamitochondria
    • Wakabayashi, T., Horiuchi, M., Sakaguchi, M., et al., 1984. Mechanism of hepatic megamitochondria formation by ammonia derivatives. Correlation between structures of chemicals and their ability to induce the formation of megamitochondria. Eur. J. Biochem. 143, 455-465
    • (1984) Eur. J. Biochem. , vol.143 , pp. 455-465
    • Wakabayashi, T.1    Horiuchi, M.2    Sakaguchi, M.3
  • 72
    • 0040735749 scopus 로고    scopus 로고
    • Structural changes of mitochondria during free radical-induced apoptosis
    • Wakabayashi, T., Spodnik, J.H., 2000. Structural changes of mitochondria during free radical-induced apoptosis. Folia Morphol. 59, 61-75
    • (2000) Folia Morphol , vol.59 , pp. 61-75
    • Wakabayashi, T.1    Spodnik, J.H.2
  • 73
    • 0016247959 scopus 로고
    • Mitochondrial DNA synthesis during the cell cycle of saccharomyces cerevisiae
    • Wells, J.R., 1974. Mitochondrial DNA synthesis during the cell cycle of saccharomyces cerevisiae. Exp. Cell Res. 85, 278-286
    • (1974) Exp. Cell Res. , vol.85 , pp. 278-286
    • Wells, J.R.1
  • 74
    • 0029973294 scopus 로고    scopus 로고
    • Stable and specific binding of heat shock protein 90 by geldanamycin disrupts glucocorticoid receptor function in intact cells
    • Whitesell, L., Cook, P., 1996. Stable and specific binding of heat shock protein 90 by geldanamycin disrupts glucocorticoid receptor function in intact cells. Mol. Endocrinol. 10, 705-712
    • (1996) Mol. Endocrinol. , vol.10 , pp. 705-712
    • Whitesell, L.1    Cook, P.2
  • 76
    • 0029052321 scopus 로고
    • Inhibition of protein tyrosine phosphorylation in T cells by a novel immunosuppressive agent, leflunomide
    • Xu, X., Williams, J.W., Bremer, E.G., Finnegan, A., Chong, A.S., 1995. Inhibition of protein tyrosine phosphorylation in T cells by a novel immunosuppressive agent, leflunomide. J. Biol. Chem. 270, 12398-12403
    • (1995) J. Biol. Chem. , vol.270 , pp. 12398-12403
    • Xu, X.1    Williams, J.W.2    Bremer, E.G.3    Finnegan, A.4    Chong, A.S.5
  • 77
    • 0030014489 scopus 로고    scopus 로고
    • Two activities of the immunosuppressive metabolite of leflunomide A77 1726
    • Xu, X., Williams, J.W., Gong, H., Finnegan, A., Chong, A. S.-F., 1996. Two activities of the immunosuppressive metabolite of leflunomide, A77 1726. Biochem. Pharmacol. 52, 527-534
    • (1996) Biochem. Pharmacol. , vol.52 , pp. 527-534
    • Xu, X.1    Williams, J.W.2    Gong, H.3    Finnegan, A.4    Chong, A.-F.5
  • 78
    • 0033525615 scopus 로고    scopus 로고
    • The machinery of mitochondrial inheritance and behavior
    • Yaffe, M.P., 1999. The machinery of mitochondrial inheritance and behavior. Science 283, 1493-1497
    • (1999) Science , vol.283 , pp. 1493-1497
    • Yaffe, M.P.1
  • 79
    • 0023245267 scopus 로고
    • Adhesion and growth of rat liver epithelial cells on an extracellular matrix proteins from fibroblast conditioned medium
    • Yamada, M., Okigaki, T., Awai, M., 1987. Adhesion and growth of rat liver epithelial cells on an extracellular matrix proteins from fibroblast conditioned medium. Cell Struct. Funct. 12, 53-62
    • (1987) Cell Struct. Funct. , vol.12 , pp. 53-62
    • Yamada, M.1    Okigaki, T.2    Awai, M.3
  • 80
    • 0029101644 scopus 로고
    • Sequential reduction of mitochondrial transmembrane potential and generation of reactive oxygen species in early programmed cell death
    • Zamzami, M., Marchetti, P., Castedo, M., et al., 1995. Sequential reduction of mitochondrial transmembrane potential and generation of reactive oxygen species in early programmed cell death. J. Exp. Med. 182, 367-377
    • (1995) J. Exp. Med. , vol.182 , pp. 367-377
    • Zamzami, M.1    Marchetti, P.2    Castedo, M.3
  • 81
    • 0025197060 scopus 로고
    • 2 and vanadate concomitantly stimulates protein tyrosine phosphorylation and polyphosphoinositide breakdown in different cell lines
    • 2 and vanadate concomitantly stimulates protein tyrosine phosphorylation and polyphosphoinositide breakdown in different cell lines. Biochemistry 29, 10240-10245
    • (1990) Biochemistry , vol.29 , pp. 10240-10245
    • Zick, Y.1    Sagi-Eisenberg, R.A.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.