The role of the hospital environment in preventing healthcare-associated infections caused by pathogens transmitted through the air

Health Environments Research and Design Journal

Volumn 7, Issue SUPPL.1, 2013, Pages 74-98

  Jacob, Jesse T ^a   Kasali, Altug ^b   Steinberg, James P ^a   Zimring, Craig ^b   Denham, Megan E ^b  

^a EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b GEORGIA INSTITUTE OF TECHNOLOGY   (United States)

Author keywords

Built environment; Evidence based design; Healthcare association infection; Hospital; Infection control

Indexed keywords

EID: 84897584644     PISSN: 19375867     EISSN: None     Source Type: Journal    
DOI: 10.1177/193758671300701s07     Document Type: Article

References (52)

1. Ahl, T., Dalen, N., Jorbeck, H., & Hoborn, J. (1995). Air contamination during hip and knee arthroplasties. Horizontal laminar-flow randomized vs. conventional ventilation. Acta Orthopaedica Scandinavica, 66(1), 17-20. doi:10.3109/17453679508994632
2. American Society of Heating, Refrigerating, and Air-Conditioning Engineers. (2012). Ventilation of Health Care Facilities. ANSI/ASHRAE/ASHE Addendum l to ANSI/ASHRAE/ ASHE Standard 170-2008. Retrieved from https://www.ashrae.org/File Library/docLib/ StdsAddenda/170_2008_l_published.pdf
3. Assadian, O., Kuelpmann, R., Zhumadilova, A., Kobayashi, H., Heidecke, C. D., & Kramer, A. (2009). Protective effect of HEPA filtered operating room air ventilation with or without laminar airflow on surgical site infections. Annals of Surgery, 250(4), 659-660.
4. Balocco, C. (2011). Hospital ventilation simulation for the study of potential exposure to contaminants. Building Simulation, 4(1), 5-20. doi:10.1007/s12273-011-0019-6
5. Beggs, C. B., Kerr, K. G., Noakes, C. J., Hathway, E. A., & Sleigh, P. A. (2008). The ventilation of multiple-bed hospital wards: Review and analysis. American Journal of Infection Control, 36(4), 250-259. doi:10.1016/j.ajic.2007.07.012
6. Berrouk, A. S., Lai, A. C. K., Cheung, A. C. T., & Wong, S. L. (2010). Experimental measurements and large eddy simulation of expiratory droplet dispersion in a mechanically ventilated enclosure with thermal effects. Building and Environment, 45(2), 371-379. Retrieved from http:// dx.doi.org/10.1016/j.buildenv.2009.06.016
7. Berthelot, P., Loulergue, P., Raberin, H., Turco, M., Mounier, C., Tran Manh Sung, R., Guyotat, D. (2006). Efficacy of environmental measures to decrease the risk of hospital-acquired aspergillosis in patients hospitalised in haematology wards. Clinical Microbiology and Infection, 12(8), 738-744.
8. Brandt, C., Hott, U., Sohr, D., Daschner, F., Gastmeier, P., & Ruden, H. (2008). Operating room ventilation with laminar airflow shows no protective effect on the surgical site infection rate in orthopedic and abdominal surgery. Annals of Surgery, 248(5), 695-700. doi:10.1097/ SLA.0b013e31818b757d
9. Breier, A. C., Brandt, C., Sohr, D., Geffers, C., & Gastmeier, P. (2011). Laminar airflow ceiling size: No impact on infection rates following hip and knee prosthesis. Infection Control and Hospital Epidemiology, 32(11), 1097-1102. doi:10.1086/662182
10. Chuaybamroong, P., Chotigawin, R., Supothina, S., Sribenjalux, P., Larpkiattaworn, S., & Wu, C. Y. (2010). Efficacy of photocatalytic HEPA filter on microorganism removal. Indoor Air, 20(3), 246-254. doi:10.1111/j.1600-0668.2010.00651.x
11. Cornet, M., Levy, V., Fleury, L., Lortholary, J., Barquins, S., Coureul, M. H., Bouvet, A. (1999). Efficacy of prevention by high-efficiency particulate air filtration or laminar airflow against Aspergillus airborne contamination during hospital renovation. Infection Control and Hospital Epidemiology, 20(7), 508-513. doi:10.1086/501661
12. Denham, M. E., Kasali, A., Steinberg, J. P., Cowan, D. Z., Zimring, C., & Jacob, J. T. (2013). The role of water in the transmission of healthcare-associated infections: Opportunities for intervention through the environment. Health Environments Research & Design Journal, 7(Suppl), 99-126.
13. Diab-Elschahawi, M., Berger, J., Blacky, A., Kimberger, O., Oguz, R., Kuelpmann, R., Assadian, O. (2011). Impact of different-sized laminar air flow versus no laminar air flow on bacterial counts in the operating room during orthopedic surgery. American Journal of Infection Control, 39(7), E25-E29. doi:10.1016/j.ajic.2010.10.035
14. Evans, R. P. (2011). Current concepts for clean air and total joint arthroplasty: Laminar airflow and ultraviolet radiation: a systematic review. Clinical Orthopaedics and Related Research, 469(4), 945-953. doi:10.1007/s11999-010-1688-7
15. Friberg, B., & Friberg, S. (2005). Aerobiology in the operating room and its implications for working standards. Proceedings of the Institution of Mechanical Engineers Part H-Journal of Engineering in Medicine, 219(H2), 153-160. doi:10.1243/095441105x9282
16. Friberg, B., Friberg, S., Burman, L. G., Lundholm, R., & Ostensson, R. (1996). Inefficiency of upward displacement operating theatre ventilation. Journal of Hospital Infection, 33(4), 263-272. doi:10.1016/s0195-6701(96)90012-2
17. Howorth, F. H. (1986). Prevention of airborne infections in operating rooms. Hospital Engineering, 40(8), 17-23.
18. Lenfestey, N. F., Denham, M. E., Hall, K. K., & Kamerow, D. B. (2013). Expert opinions on the role of facility design in the acquisition and prevention of healthcare-associated infections. Health Environments Research & Design Journal, 7(Suppl), 31-45.
19. Lim, T., Cho, J., & Kim, B. S. (2010). The influence of ward ventilation on hospital cross infection by varying the location of supply and exhaust air diffuser using CFD. Journal of Asian Architecture and Building Engineering, 9(1), 259-266.
20. Lowen, A. C, Mubareka, S., Steel, J., & Palese, P. (2007). Influenza virus transmission is dependent on relative humidity and temperature. PLoS Pathogens, 3(10), e151.
21. Memarzadeh, F. (2010). Health and safety risk assessment methodology to calculate reverse airflow tolerance in a biosafety level 3 (BSL-3) or airborne infection isolation room (AII) environment. International Journal of Risk Assessment and Management, 14(1-2), 157-175.
22. Memarzadeh, F. (2011). The environment of care and health care-associated infections: An engineering perspective. Chicago, IL: American Society of Healthcare Engineering.
23. Memarzadeh, F. (2012). Literature review of the effect of temperature and humidity on viruses. ASHRAE Transactions, 118(1), 1049-1060.
24. Miller, S. L., & Macher, J. M. (2000). Evaluation of a methodology for quantifying the effect of room air ultraviolet germicidal irradiation on airborne bacteria. Aerosol Science and Technology, 33(3), 274-295. doi:10.1080/027868200416259
25. Miner, A. L., Losina, E., Katz, J. N., Fossel, A. H., & Platt, R. (2005). Infection control practices to reduce airborne bacteria during total knee replacement: A hospital survey in four states. Infection Control and Hospital Epidemiology, 26(12), 910-915. doi:10.1086/505452
26. Montecalvo, M. A., Jarvis, W. R., Uman, J., Shay, D. K., Petrullo, C., Rodney, K., Wormser, G. P. (1999). Infection-control measures reduce transmission of vancomycin-resistant Enterococci in an endemic setting. Annals of Internal Medicine, 131(4), 269-272.
27. National Institute for Occupational Safety and Health. (2009). Environmental control for tuberculosis: Basic upper-room ultraviolet germicidal irradiation guidelines for healthcare settings. Atlanta, GA: Author. Retrieved from http://www.cdc.gov/niosh/docs/2009-105/pdfs/2009-105.pdf
28. Nielsen, P. V. (2009). Control of airborne infectious diseases in ventilated spaces. Journal of the Royal Society Interface, 6, S747-S755. doi:10.1098/rsif.2009.0228.focus
29. Nolard, N. (1994). Links between risks of aspergillosis and environmental contamination-review of the literature. Pathologie Biologie, 42(7), 706-710.
30. Ostrowsky, B. E., Trick, W. E., Sohn, A. H., Quirk, S. B., Holt, S., Carson, L. A., Jarvis, W. R. (2001). Control of vancomycin-resistant Enterococcus in health care facilities in a region. The New England Journal of Medicine, 344(19), 1427-1433.
31. Petrova, N. A., Klyasova, G. A., & Funygina, L. P. (2003). Prevalence of mycelial fungi in a hematological hospital. Terapevticheskii Arkhiv, 75(7), 58-63.
32. Pryor, F., & Messmer, P. R. (1998). The effect of traffic patterns in the OR on surgical site infections. AORN Journal, 68(4), 649-660.
33. Riley, R.L., Wells, W.F., Mills, C.C., Nyka, W., & McLean, R.L. (1957). Air hygiene in tuberculosis: Quantitative studies of infectivity and control in a pilot ward. American Review of Tuberculosis, 75, 420-431.
34. Ritter, M. A., Eitzen, H. E., French, M. L., & Hart, J. B. (1976). The effect that time, touch and environment have upon bacterial contamination of instruments during surgery. Annals of Surgery, 184(5), 642-644.
35. Ritter, M. A., French, M. L. V., & Hart, J. B. (1973). Microbiological studies in a horizontal wall less laminar air flow operating room during actual surgery. Clinical Orthopaedics and Related Research, 97, 16-18.
36. Roberts, K., Hathway, A., Fletcher, L. A., Beggs, C. B., Elliott, M. W., & Sleigh, P. A. (2006). Bioaerosol production on a respiratory ward. Indoor and Built Environment, 15(1), 35-40. doi:10.1177/1420326x06062562
37. Ryan, R. M., Wilding, G. E., Wynn, R. J., Welliver, R. C., Holm, B. A., & Leach, C. L. (2011). Effect of enhanced ultraviolet germicidal irradiation in the heating ventilation and air conditioning system on ventilator-associated pneumonia in a neonatal intensive care unit. Journal of Perinatology, 31(9), 607-614. doi:10.1038/jp.2011.16
38. Saravia, S. A., Raynor, P. C., & Streifel, A. J. (2007). A performance assessment of airborne infection isolation rooms. American Journal of Infection Control, 35(5), 324-331.
39. Scaltriti, S., Cencetti, S., Rovesti, I., Marchesi, I., Bargellini, A., & Borella, P. (2007). Risk factors for particulate and microbial contamination of air in operating theatres. Journal of Hospital Infection, 66(4), 320326. doi:10.1016/j.jhin.2007.05.019
40. Sehulster, L., & Chinn, R. Y. (2003). Guidelines for environmental infection control in healthcare facilities. Recommendations of CDC and the Healthcare Infection Control Practices Advisory Committee (HICPAC). MMWR Recomendations and Reports, 52(RR-10), 1-42.
41. Sherertz, R. J., Belani, A., Kramer, B. S., Elfenbein, G. J., Weiner, R. S., Sullivan, M. L., Samsa, G. P. (1987). Impact of air filtration on nosocomial Aspergillus infections. Unique risk of bone marrow transplant recipients. The American Journal of Medicine, 83(4), 709-718.
42. Shiomori, T., Miyamoto, H., Makishima, K., Yoshida, M., Fujiyoshi, T., Udaka, T., Hiraki, N. (2002). Evaluation of bedmaking-related airborne and surface methicillin-resistant Staphylococcus aureus contamination. Journal of Hospital Infection, 50(1), 30-35.
43. Stelfox, H. T., Bates, D. W., & Redelmeier, D. A. (2003). Safety of patients isolated for infection control. Journal of the American Medical Association, 290(14), 1899-1905. doi:10.1001/ jama.290.14.1899
44. U.S. Department of Energy. (2005). Technical standard: Specification for HEPA filters used by DOE contractors. Washington, DC: U.S. Department of Health & Human Services.
45. Van Der Waaij, D., Heidt, P. J., & Hendriks, W. D. H. (1974). Bacteriological evaluation of a laminar cross flow tunnel for surgery under operational conditions. Journal of Hygiene (London), 72(2), 145-153.
46. Verdenelli, M. C., Cecchini, C., Orpianesi, C., Dadea, G. M., & Cresci, A. (2003). Efficacy of antimicrobial filter treatments on microbial colonization of air panel filters. Journal of Applied Microbiology, 94(1), 9-15. doi:10.1046/j.1365-2672.2003.01820.x
47. Wang, B., Mortazavi, R., & Haghighat, F. (2009). Evaluation of modeling and measurement techniques of ultraviolet germicidal irradiation effectiveness-Towards the design of immune buildings. Indoor and Built Environment, 18(2), 101-112. doi:10.1177/1420326x09103024
48. Whyte, W., Shaw, B. H., & Barnes, R. (1973). A bacteriological evaluation of laminar-flow systems for orthopaedic surgery. Journal of Hygiene (London), 71(3), 559-564.
49. Whyte, W., Shaw, B. H., & Freeman, M. A. (1974). An evaluation of a partial-walled laminar-flow operating room. Journal of Hygiene (London), 73(1), 61-74.
50. World Health Organization. (1999). Guidelines for the prevention of tuberculosis in health care facilities in resource-limited settings. Geneva, Switzerland: Author. Retrieved from http:// www.who.int/tb/publications/who_tb_99_269.pdf
51. Yang, W., & Marr, L. C. (2011). Dynamics of airborne influenza A viruses indoors and dependence on humidity. PLoS One, 6(6), e21481.
52. Zimring, C., Jacob, J. T., Denham, M. E., Kamerow, D. B., Hall, K. K., Cowan, D. Z., Steinberg, J. P. (2013). The role of facility design in preventing the transmission of healthcare-associated infections: Background and conceptual framework. Health Environments Research & Design Journal, 7(Suppl), 18-30.