Differentiating malignant from benign thrombosis in hepatocellular carcinoma: Contrast-enhanced ultrasound

Abdominal Imaging

Volumn 39, Issue 1, 2014, Pages 153-161

  Raza, S Arsalan ^a,b   Jang, Hyun Jung ^a   Kim, Tae Kyoung ^a  

^a UNIVERSITY OF TORONTO   (Canada)

^b Cape Breton Regional Hospital   (Canada)

Author keywords

Contrast enhanced ultrasound; Hepatocellular carcinoma; Portal vein thrombosis

Indexed keywords

ANTINEOPLASTIC AGENT; PERFLUTREN;

ADULT; AGED; ARTICLE; BENIGN LIVER VEIN THROMBOSIS; BENIGN PORTAL VEIN THROMBOSIS; CANCER DIAGNOSIS; CANCER RADIOTHERAPY; CANCER SURGERY; CHEMOEMBOLIZATION; COMPUTER ASSISTED TOMOGRAPHY; CONTRAST ENHANCED ULTRASONOGRAPHY; CONTROLLED STUDY; DIAGNOSTIC ACCURACY; DIAGNOSTIC TEST ACCURACY STUDY; ECHOGRAPHY; FEMALE; FOLLOW UP; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; IMAGE GUIDED BIOPSY; LIVER CELL CARCINOMA; LIVER VEIN THROMBOSIS; MAJOR CLINICAL STUDY; MALE; MALIGNANT LIVER VEIN THROMBOSIS; MALIGNANT PORTAL VEIN THROMBOSIS; MULTIMODALITY CANCER THERAPY; NUCLEAR MAGNETIC RESONANCE IMAGING; PORTAL VEIN THROMBOSIS; PREDICTIVE VALUE; PRIORITY JOURNAL; RADIOFREQUENCY ABLATION; RECEIVER OPERATING CHARACTERISTIC; RETROSPECTIVE STUDY; SENSITIVITY AND SPECIFICITY; TUMOR DIAGNOSIS; TUMOR THROMBUS; ULTRASOUND SCANNER; VERY ELDERLY; BUDD CHIARI SYNDROME; COMPLICATION; IMAGE ENHANCEMENT; LIVER TUMOR; MIDDLE AGED; PORTAL VEIN; PROCEDURES; VEIN THROMBOSIS;

AGED; AGED, 80 AND OVER; BUDD-CHIARI SYNDROME; CARCINOMA, HEPATOCELLULAR; FEMALE; HUMANS; IMAGE ENHANCEMENT; LIVER NEOPLASMS; MALE; MIDDLE AGED; PORTAL VEIN; RETROSPECTIVE STUDIES; SENSITIVITY AND SPECIFICITY; ULTRASONOGRAPHY; VENOUS THROMBOSIS;

EID: 84897584352     PISSN: 09428925     EISSN: 14320509     Source Type: Journal    
DOI: 10.1007/s00261-013-0034-4     Document Type: Article

References (38)

1. Pirisi M, Avellini C, Fabris C, et al. (1998) Portal vein thrombosis in hepatocellular carcinoma: age and sex distribution in an autopsy study. J Cancer Res Clin Oncol 124(7):397-400. doi: 10.1007/s004320050189
2. Pawarode A, Voravud N, Sriuranpong V, Kullavanijaya P, Patt YZ (1998) Natural history of untreated primary hepatocellular carcinoma: a retrospective study of 157 patients. Am J Clin Oncol 21(4):386-391
3. Takizawa D, Kakizaki S, Sohara N, et al. (2007) Hepatocellular carcinoma with portal vein tumor thrombosis: clinical characteristics, prognosis, and patient survival analysis. Dig Dis Sci 52(11):3290-3295. doi: 10.1007/s10620-007-9808-2
4. Sakata J, Shirai Y, Wakai T, et al. (2008) Preoperative predictors of vascular invasion in hepatocellular carcinoma. Eur J Surg Oncol (EJSO) 34(8):900-905. doi: 10.1016/j.ejso.2008.01.031
5. Ogren M, Bergqvist D, Bjorck M, et al. (2006) Portal vein thrombosis: prevalence, patient characteristics and lifetime risk: a population study based on 23,796 consecutive autopsies. World J Gastroenterol 12(13):2115-2119
6. Francoz C, Valla D, Durand F (2012) Portal vein thrombosis, cirrhosis, and liver transplantation. J Hepatol 57(1):203-212. doi: 10.1016/j.jhep.2011.12. 034
7. Sotiropoulos G, Radtke A, Schmitz K, et al. (2008) Liver transplantation in the setting of hepatocellular carcinoma and portal vein thrombosis: a challenging dilemma? Dig Dis Sci 53(7):1994-1999. doi: 10.1007/s10620-007-0099-4
8. Lim JH, Auh YH (1992) Hepatocellular carcinoma presenting only as portal venous tumor thrombosis: CT demonstration. J Comput Assist Tomogr 16(1):103-106
9. Tanaka K, Numata K, Okazaki H, et al. (1993) Diagnosis of portal vein thrombosis in patients with hepatocellular carcinoma: efficacy of color Doppler sonography compared with angiography. AJR Am J Roentgenol 160(6):1279-1283
10. Van Gansbeke D, Avni EF, Delcour C, Engelholm L, Struyven J (1985) Sonographic features of portal vein thrombosis. AJR Am J Roentgenol 144(4):749-752
11. Dodd GD 3rd, Memel DS, Baron RL, Eichner L, Santiguida LA (1995) Portal vein thrombosis in patients with cirrhosis: does sonographic detection of intrathrombus flow allow differentiation of benign and malignant thrombus? AJR Am J Roentgenol 165(3):573-577
12. Ricci P, Cantisani V, Biancari F, et al. (2000) Contrast-enhanced color Doppler US in malignant portal vein thrombosis. Acta Radiol 41(5):470-473
13. Tublin ME, Dodd GD, Baron RL (1997) Benign and malignant portal vein thrombosis: differentiation by CT characteristics. ARJ Am J Roentgenol 168(3):719-723
14. Levy HM, Newhouse JH (1988) MR imaging of portal vein thrombosis. AJR Am J Roentgenol 151(2):283-286
15. Zirinsky K, Markisz JA, Rubenstein WA, et al. (1988) MR imaging of portal venous thrombosis: correlation with CT and sonography. AJR Am J Roentgenol 150(2):283-288
16. Okumura A, Watanabe Y, Dohke M, et al. (1999) Contrast-enhanced three-dimensional MR portography. Radiographics 19(4):973-987
17. Rossi S, Rosa L, Ravetta V, et al. (2006) Contrast-enhanced versus conventional and color Doppler sonography for the detection of thrombosis of the portal and hepatic venous systems. AJR Am J Roentgenol 186(3):763-773. doi: 10.2214/AJR.04.1218
18. Rossi S, Ghittoni G, Ravetta V, et al. (2008) Contrast-enhanced ultrasonography and spiral computed tomography in the detection and characterization of portal vein thrombosis complicating hepatocellular carcinoma. Eur Radiol 18(8):1749-1756. doi: 10.1007/s00330-008-0931-z
19. Sorrentino P, D'Angelo S, Tarantino L, et al. (2009) Contrast-enhanced sonography versus biopsy for the differential diagnosis of thrombosis in hepatocellular carcinoma patients. World J Gastroenterol 15(18):2245-2251
20. Song ZZ, Huang M, Jiang TA, et al. (2010) Diagnosis of portal vein thrombosis discontinued with liver tumors in patients with liver cirrhosis and tumors by contrast-enhanced US: a pilot study. Eur J Radiol 75(2):185-188. doi: 10.1016/j.ejrad.2009.04.021
21. Piscaglia F, Gianstefani A, Ravaioli M, et al. (2010) Criteria for diagnosing benign portal vein thrombosis in the assessment of patients with cirrhosis and hepatocellular carcinoma for liver transplantation. Liver Transpl 16(5):658-667. doi: 10.1002/lt.22044
22. Obuchowski NA (2005) ROC analysis. AJR Am J Roentgenol 184(2):364-372
23. Cicchetti DV, Sparrow SA (1981) Developing criteria for establishing interrater reliability of specific items: applications to assessment of adaptive behavior. Am J Ment Defic 86(2):127-137
24. Minagawa M, Makuuchi M (2006) Treatment of hepatocellular carcinoma accompanied by portal vein tumor thrombus. World J Gastroenterol 12(47):7561-7567
25. Minagawa M, Makuuchi M, Takayama T, Ohtomo K (2001) Selection criteria for hepatectomy in patients with hepatocellular carcinoma and portal vein tumor thrombus. Ann Surg 233(3):379-384
26. Shah ZK, McKernan MG, Hahn PF, Sahani DV (2007) Enhancing and expansile portal vein thrombosis: value in the diagnosis of hepatocellular carcinoma in patients with multiple hepatic lesions. AJR Am J Roentgenol 188(5):1320-1323. doi: 10.2214/AJR.06.0134
27. Vilgrain V, Lebrec D, Menu Y, Scherrer A, Nahum H (1990) Comparison between ultrasonographic signs and the degree of portal hypertension in patients with cirrhosis. Gastrointest Radiol 15(3):218-222
28. Barrett BJ, Parfrey PS (2006) Clinical practice. Preventing nephropathy induced by contrast medium. N Engl J Med 354(4):379-386. doi: 10.1056/NEJMcp050801
29. Peak AS, Sheller A (2007) Risk factors for developing gadolinium-induced nephrogenic systemic fibrosis. Ann Pharmacother 41(9):1481-1485. doi: 10.1345/aph.1K295
30. Burns PN, Wilson SR, Simpson DH (2000) Pulse inversion imaging of liver blood flow: improved method for characterizing focal masses with microbubble contrast. Investig Radiol 35(1):58-71
31. Choi BI, Kim TK, Han JK, et al. (1996) Power versus conventional color Doppler sonography: comparison in the depiction of vasculature in liver tumors. Radiology 200(1):55-58
32. Marshall MM, Beese RC, Muiesan P, et al. (2002) Assessment of portal venous system patency in the liver transplant candidate: a prospective study comparing ultrasound, microbubble-enhanced colour Doppler ultrasound, with arteriography and surgery. Clin Radiol 57(5):377-383. doi: 10.1053/crad.2001. 0839
33. Tarantino L, Francica G, Sordelli I, et al. (2006) Diagnosis of benign and malignant portal vein thrombosis in cirrhotic patients with hepatocellular carcinoma: color Doppler US, contrast-enhanced US, and fine-needle biopsy. Abdom Imaging 31(5):537-544. doi: 10.1007/s00261-005-0150-x
34. Danila M, Sporea I, Popescu A, Sirli R, Sendroiu M (2011) The value of contrast enhanced ultrasound in the evaluation of the nature of portal vein thrombosis. Med Ultrasonogr 13(2):102-107
35. Dusenbery D, Dodd GD, Carr BI (1995) Percutaneous fine-needle aspiration of portal vein thrombi as a staging technique for hepatocellular carcinoma. Cytologic findings of 46 patients. Cancer 75(8):2057-2062. doi:10.1002/1097- 0142(19950415)75:8<2057::aid-cncr2820750805>3.0.co;2-k
36. Kubo S, Takemura S, Yamamoto S, et al. (2007) Risk factors for massive blood loss during liver resection for hepatocellular carcinoma in patients with cirrhosis. Hepatogastroenterology 54(75):830-833
37. Bravo AA, Sheth SG, Chopra S (2001) Liver biopsy. N Engl J Med 344(7):495-500. doi: 10.1056/NEJM200102153440706
38. Vilana R, Bru C, Bruix J, et al. (1993) Fine-needle aspiration biopsy of portal vein thrombus: value in detecting malignant thrombosis. AJR Am J Roentgenol 160(6):1285-1287