Targeting the splicing of mRNA in autoimmune diseases: BAFF inhibition in sjögren's syndrome as a proof of concept

Molecular Therapy

Volumn 22, Issue 4, 2014, Pages 821-827

  Roescher, N ^a,b   Vosters, J L ^a,b   Alsaleh, G ^c   Dreyfus, P ^d   Jacques, S ^e   Chiocchia, G ^e   Sibilia, J ^c   Tak, P P ^a   Chiorini, J A ^b   Mariette, X ^f   Gottenberg, Jacques Eric ^c  

^a ACADEMIC MEDICAL CENTER   (Netherlands)

^b NATIONAL INSTITUTE OF DENTAL AND CRANIOFACIAL RESEARCH   (United States)

^c UNIVERSITÉ DE STRASBOURG   (France)

^d Sorbonne Université   (France)

^e INSERM   (France)

^f UNIVERSITÉ PARIS SACLAY   (France)

Author keywords

[No Author keywords available]

Indexed keywords

B CELL ACTIVATING FACTOR; DELTA B CELL ACTIVATING FACTOR; GENE THERAPY AGENT; LYMPHOCYTE ANTIGEN; MESSENGER RNA; PARVOVIRUS VECTOR; U7 RNA; UNCLASSIFIED DRUG; SMALL NUCLEAR RNA; TNFSF13B PROTEIN, MOUSE; U7 SMALL NUCLEAR RNA;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; EPITHELIUM CELL; EXON SKIPPING; FEMALE; IN VITRO STUDY; IN VIVO STUDY; LYMPHOCYTIC INFILTRATION; MOUSE; MUCOSAL DRYNESS; NONHUMAN; PROTEIN EXPRESSION; PROTEIN SECRETION; SALIVATION; SJOEGREN SYNDROME; VIRAL GENE DELIVERY SYSTEM; VIRAL GENE THERAPY; ANIMAL; ANTAGONISTS AND INHIBITORS; B LYMPHOCYTE; BIOSYNTHESIS; DEPENDOPARVOVIRUS; EXON; GENETICS; HUMAN; LYMPHOCYTE ACTIVATION; METABOLISM; NONOBESE DIABETIC MOUSE; PATHOLOGY; RNA SPLICING; SJOGREN'S SYNDROME;

ADENO-ASSOCIATED VIRUS; MUS;

ANIMALS; B-CELL ACTIVATING FACTOR; B-LYMPHOCYTES; DEPENDOVIRUS; EXONS; HUMANS; LYMPHOCYTE ACTIVATION; MICE; MICE, INBRED NOD; RNA SPLICING; RNA, MESSENGER; RNA, SMALL NUCLEAR; SJOGREN'S SYNDROME;

EID: 84897569619     PISSN: 15250016     EISSN: 15250024     Source Type: Journal    
DOI: 10.1038/mt.2013.275     Document Type: Article

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