A novel injectable borate bioactive glass cement as an antibiotic delivery vehicle for treating osteomyelitis

PLoS ONE

Volumn 9, Issue 1, 2014, Pages

  Ding, Hao ^a   Zhao, Cun Ju ^b   Cui, Xu ^c   Gu, Yi Fei ^c   Jia, Wei Tao ^a   Rahaman, Mohamed N ^d   Wang, Yang ^a   Huang, Wen Hai ^c   Zhang, Chang Qing ^a  

^a SHANGHAI JIAO TONG UNIVERSITY   (China)

^b LIAOCHENG PEOPLE'S HOSPITAL   (China)

^c TONGJI UNIVERSITY   (China)

^d Architectural and Environmental Engineering   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BORATE BIOACTIVE GLASS CEMENT; CALCIUM SULFATE; CEMENT; GLASS; PHOSPHATE BUFFERED SALINE; UNCLASSIFIED DRUG; VANCOMYCIN;

ADULT; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BIOCOMPATIBILITY; BONE DEFECT; BONE RADIOGRAPHY; BONE REGENERATION; COMPRESSIVE STRENGTH; CONTROLLED STUDY; DRUG BLOOD LEVEL; METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS INFECTION; MINIMUM INHIBITORY CONCENTRATION; NEW ZEALAND WHITE (RABBIT); NONHUMAN; OSTEOMYELITIS; SUSTAINED DRUG RELEASE; TIBIA;

ANIMALS; ANTI-BACTERIAL AGENTS; BIOCOMPATIBLE MATERIALS; BORATES; COMPRESSIVE STRENGTH; DISEASE MODELS, ANIMAL; DRUG CARRIERS; GLASS; KINETICS; MATERIALS TESTING; METHICILLIN-RESISTANT STAPHYLOCOCCUS AUREUS; MICROBIAL SENSITIVITY TESTS; OSTEOMYELITIS; RABBITS; STAPHYLOCOCCAL INFECTIONS; VANCOMYCIN;

EID: 84897569436     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0085472     Document Type: Article

References (40)

1. Simpson AH, Deakin M, Latham JM (2001) Chronic osteomyelitis. The effect of the extent of surgical resection on infection-free survival. J Bone Joint Surg Br 83: 403-407.
2. Cierny G, Mader JT, Penninck JJ (2003) A clinical staging system for adult osteomyelitis. Clin Orthop Relat Res 414: 7-24.
3. Hanssen AD (2005) Local antibiotic delivery vehicles in the treatment of musculoskeletal infection. Clin Orthop Relat Res 437: 91-96.
4. Joosten U, Joist A, Frebel T, Brandt B, Diederichs S, et al. (2004) Evaluation of an in situ setting injectable calcium phosphate as a new carrier material for gentamicin in the treatment of chronic osteomyelitis: studies in vitro and in vivo. Biomaterials 25: 4287-4295. (Pubitemid 38388590)
5. Jiang JL, Li YF, Fang YL, Zhou J, Li XL, et al. (2012) Vancomycin-loaded nano-hydroxyapatite pellets to treat MRSA-induced chronic osteomyelitis with bone defect in rabbits. Inflamm Res 61: 207-215.
6. Kluin OS, van der Mer HC, Busscher HJ, Neut D (2013) Biodegradable vs non-biodegradable antibiotic delivery devices in the treatment of osteomyelitis. Expert Opin Drug Deliv 10: 341-351.
7. McLaren AC (2004) Alternative materials to acrylic bone cement for delivery of depot antibiotics in orthopaedic infections. Clin Orthop Relat Res 427: 101- 106.
8. Marion NW, Liang W, Reilly G, Day DE, Rahaman MN, et al. (2005) Borate glass supports the in vitro osteogenic differentiation of human mesenchymal stem cells. Mech Adv Mater Struct 12: 1-8.
9. Yao A, Wang D, Fu Q, Huang W, Rahaman MN (2007) Preparation of bioactive glasses with controllable degradation behavior and their bioactive characterization. China Sci Bull 52: 272-276. (Pubitemid 46361022)
10. Brown RF, Rahaman MN, Dwilewicz AB, Huang W, Day DE, et al. (2009) Effect of borate glass composition on its conversion to hydroxyapatite and on the proliferation of MC3T3-E1 Cells. J Biomed Mater Res A 88: 392-400.
11. Yao A, Wang D, Huang W, Fu Q, Rahaman MN, et al. (2007) In vitro bioactive characteristics of borate-based glasses with controllable degradation behavior. J Am Ceram Soc 90: 303-306. (Pubitemid 46087976)
12. Xie Z, Liu X, Jia W, Zhang C, Huang W, et al. (2009) Treatment of osteomyelitis and repair of bone defect by degradable bioactive borate glass releasing vancomycin. J Control Release 139: 118-126.
13. Jia WT, Zhang X, Zhang CQ, Liu X, Huang WH, et al. (2010) Elution characteristics of teicoplanin-loaded biodegradable borate glass/chitosan composite. Int J Pharm 387: 184-186.
14. Jia WT, Zhang X, Luo SH, Liu X, Huang WH, et al. (2010) Novel borate glass/chitosan composite as a delivery vehicle for teicoplanin in the treatment of chronic osteomyelitis. Acta Biomater 6: 812-819.
15. Hui T, Yongqing X, Tiane Z, Gang L, Yongqang Y, et al. (2009) Treatment of osteomyelitis by liposomal gentamicin-impregnated calcium sulfate. Arch Orthop Trauma Surg 129: 1301-1308.
16. Kanellakopoulou K, Galanopoulos I, Soranoqlou V, Tsaganos T, Tziortzioti V, et al. (2009) Treatment of experimental osteomyelitis caused by methicillin-resistant Staphylococcus aureus with a synthetic carrier of calcium sulphate (Stimulan) releasing moxifloxacin. Int J Antimicrob Agents 33: 354-359.
17. Jia WT, Luo SH, Zhang CQ, Wang JQ (2010) In vitro and in vivo efficacies of teicoplanin-loaded calcium sulfate for treatment of chronic methicillin-resistant Staphylococcus aureus osteomyelitis. Antimicrob Agents Chemother 54: 170- 176.
18. Rauschmann MA, Wichelhaus TA, Stirnal V, Dingeldein E, Zichner L, et al. (2005) Nanocrystalline hydroxyapatite and calcium sulphate as biodegradable composite carrier material for local delivery of antibiotics in bone infections. Biomaterials 26: 2677-2684. (Pubitemid 39600720)
19. Englert C, Angele P, Fierlbeck J, Dendorfer S, Schubert T, et al. (2007) Conductive bone substitute material with variable antibiotic delivery. Un-fallchirurg 110: 408-413. (Pubitemid 46980453)
20. Cevher E, Orhan Z, Mulazimoglu L, Sensoy D, Alper M, et al. (2006) Characterization of biodegradable chitosan microspheres containing vancomycin and treatment of experimental osteomyelitis caused by methicillin-resistant Staphylococcus aureus with prepared microspheres. Int J Pharm 317: 127-135.
21. Zhang Y, Zhang M (2002) Calcium phosphate/chitosan composite scaffolds for controlled in vitro antibiotic drug release. J Biomed Mater Res 62: 378-386. (Pubitemid 35332201)
22. Murakami K, Minamide W, Wada K (1991) Identification of methicillin-resistant strains of staphylococci by polymerase chain reaction. J Clin Microbiol 29: 2240-2244.
23. ASTM International C266-99- Standard test method for time of setting of hydraulic-cement paste by Gillmore needles (2007).
24. Ginebra M, Rilliard A, Fernández E, Elvira C, San Román J, et al. (2001) Mechanical and rheological improvement of a calcium phosphate cement by the addition of a polymeric drug. J Biomed Mater Res 57: 113-118. (Pubitemid 32661259)
25. McCann SJ, White LO, Keevil B (2002) Assay of teicoplanin in serum: comparison of high-performance liquid chromatography and fluorescence polarization immunoassay. J Antimicrob Chemother 50: 107-110. (Pubitemid 34785262)
26. National Committee for Clinical Laboratory Standards (2000) Methods for dilution antimicrobial susceptibility tests for bacteria that grow aerobically, 5th ed. Approved standard M7-A5. NCCLS, Wayne, PA.
27. Norden CW, Myerowitz RL, Keleti E (1980) Experimental osteomyelitis due to Staphylococcus aureus or Pseudomonas aeruginosa: a radiographic-pathological correlative analysis. Br J Exp Pathol 61: 451-460. (Pubitemid 10024409)
28. Smeltzer MS, Thomas JR, Hickmon SG, Skinner RA, Nelson CL, et al. (1997) Characterization of a rabbit model of staphylococcal osteomyelitis. J Orthop Res 15: 414-421. (Pubitemid 27327618)
29. Chang W, Colangeli M, Colangeli S, Di Bella C, Gozzi E, et al. (2007) Adult osteomyelitis: debridement versus debridement plus osteoset T pellets. Acta Orthop Belq 73: 238-243.
30. Yokoyama A, Yamamoto S, Kawasaki T, Kohgo T, Nakasu M (2002) Development of calcium phosphate cement using chitosan and citric acid for bone substitute materials. Biomaterials 23: 1091-1101. (Pubitemid 33109040)
31. Buranapanitkit B, Srinilta V, Ingviga N, Oungbho K, Geater A, et al. (2004) The efficacy of a hydroxyapatite composite as a biodegradable antibiotic delivery system. Clin Orthop Relat Res 424: 244-252. (Pubitemid 38890886)
32. Liu H, Li H, Cheng W, Yang Y, Zhu M, et al. (2006) Novel injectable calcium phosphate/chitosan composites for bone substitute materials. Acta Biomater 2: 557-565. (Pubitemid 44177339)
33. Goldstein SA (1987) The mechanical properties of trabecular bone: dependence on anatomic location and function. J Biomech 20: 1055-1061.
34. Arcos D, Ragel CV, Vallet-Regi M (2001) Bioactivity in glass/PMAA composites used as drug delivery system. Biomaterials 22: 701-708. (Pubitemid 32114124)
35. Phaechamud T, Charoenteeraboon J (2008) Antibacterial activity and drug release of chitosan sponge containing doxycycline hyclate. AAPS Pharm Sci Tech 9: 829-835.
36. Haleem AA, Rouse MS, Lewallen DG, HanssenAD, Steckelberg JM, et al. (2004) Gentamicin and vancomycin do not impair experimental fracture healing. Clin Orthop Relat Res 427: 22-24. (Pubitemid 39362825)
37. Antoci V Jr, Adams CS, Hickok NJ, Shapiro IM, Parvizi J (2007) Antibiotics for local delivery systems cause skeletal cell toxicity in vitro. Clin Orthop Relat Res 462: 200-206. (Pubitemid 47367864)
38. Patwardhan S, Shyam AK, Mody RA, Sancheti PK, Mehta R, et al. (2013) Reconstruction of bone defects after osteomyelitis with nonvascularized fibular graft: a retrospective stuyd in twenty-six children. J Bone Joint Surg Am 95: e561-566.
39. Chang W, Colangeli M, Colangeli S, Di Bella C, Gozzi E, et al. (2007) Adult osteomyelitis: debridement versus debridement plus Osteoset T pellets. Acta Orthop Belg 73: 238-243.
40. Sanicola SM, Albert SF (2005) The in vitro elution characteristics of vancomycin and tobramycin from calcium sulfate beads. J Foot Ankle Surg 44: 121-124. (Pubitemid 40321545)