Treatment of osteomyelitis by liposomal gentamicin-impregnated calcium sulfate

Archives of Orthopaedic and Trauma Surgery

Volumn 129, Issue 10, 2009, Pages 1301-1308

  Hui, Tang ^a,b   Yongqing, Xu ^a   Tiane, Zheng ^a   Gang, Li ^a   Yonggang, You ^a   Muyao, Jiang ^a   Jun, Li ^a   Jing, Ding ^a  

^a KUNMING GENERAL HOSPITAL   (China)

^b THIRD MILITARY MEDICAL UNIVERSITY   (China)

Author keywords

Bacterial biofilms; Cationic liposomes; Gentamicin; Osteomyelitis; Staphylococcus aureus

Indexed keywords

CALCIUM SULFATE; GENTAMICIN; LIPOSOME;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIMICROBIAL ACTIVITY; ARTICLE; BIOFILM; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG DELIVERY SYSTEM; DRUG DOSAGE FORM COMPARISON; DRUG EFFICACY; DRUG RELEASE; ERADICATION THERAPY; IN VITRO STUDY; IN VIVO STUDY; LIPOSOMAL DELIVERY; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN; OSTEOMYELITIS; PRIORITY JOURNAL; STAPHYLOCOCCUS AUREUS;

ANIMALS; CALCIUM SULFATE; CATIONS; DRUG CARRIERS; GENTAMICINS; LIPOSOMES; MICROBIAL SENSITIVITY TESTS; OSTEOMYELITIS; RABBITS; STAPHYLOCOCCAL INFECTIONS; TREATMENT OUTCOME;

EID: 69249248222     PISSN: 09368051     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00402-008-0782-8     Document Type: Article

References (33)

1. Berestein GL (1987) Liposomes as carriers of antimicrobial agents. Antimicrob Agents Chemother 31:675-678
2. Ceri H, Olson ME, Stremick C, Read RR, Morck D, Buret A (1999) The Calgary biofilm device: New technology for rapid determination of antibiotic susceptibilities of bacterial biofilms. J Clin Microbiol 37:1771-1776
3. Chang W, Colangeli M, Colangeli S, Di Bella C, Gozzi E, Donati D (2007) Adult osteomyelitis: Debridement versus debridement plus Osteoset T pellets. Acta Orthop Belg 73:238-243
4. Costerton JW, Stewart PS, Greenberg EP (1999) Bacterial biofilms: A common cause of persistent infections. Science 284:1318-1322. doi: 10.1126/science.284.5418.1318
5. Dunne WM Jr (2002) Bacterial adhesion: Seen any good biofilms lately? Clin Microbiol Rev 15:155-166. doi: 10.1128/CMR.15.2.155-166.2002
6. Eng RH, Padberg FT, Smith SM, Tan EN, Cherubin CE (1991) Bactericidal effects of antibiotics on slowly growing and nongrowing bacteria. Antimicrob Agents Chemother 35:1824-1828
7. Faber C, Stallmann HP, Lyaruu DM, de Blieck JM, Bervoets TJ, van Nieuw Amerongen A, Wuisman PI (2003) Release of antimicrobial peptide Dhvar-5 from polymethylmethacrylate beads. J Antimicrob Chemother 51:1359-1364. doi: 10.1093/jac/dkg258
8. Furneri PM, Fresta M, Puglisi G, Tempera G (2000) Ofloxacinloaded liposomes: In vitro activity and drug accumulation in bacteria. Antimicrob Agents Chemother 44:2458-2464. doi: 10.1128/ AAC.44.9.2458-2464.2000
9. Hienz SA, Sakamoto H, Flock JI, Mörner AC, Reinholt FP, Heimdahl A, Nord CE (1995) Development and characterization of a new model of hematogenous osteomyelitis in the rat. J Infect Dis 171:1230-1236
10. Illera JC, González Gil A, Silván G, Illera M (2000) The effects of different anaesthetic treatments on the adreno-cortical functions and glucose levels in NZW rabbits. J Physiol Biochem 56:329-336
11. Ince A, Schütze N, Hendrich C, Jakob F, Eulert J, Löhr JF (2007) Effect of polyhexanide and gentamycin on human osteoblasts and endothelial cells. Swiss Med Wkly 137:139-145
12. Jones MN (2005) Use of liposomes to deliver bactericides to bacterial biofilms. Methods Enzymol 391:211-228. doi: 10.1016/S0076-6879(05)91013-6
13. Kadry AA, Al-Suwayeh SA, Abd-Allah AR, Bayomi MA (2004) Treatment of experimental osteomyelitis by liposomal antibiotics. J Antimicrob Chemother 54:1103-1108. doi: 10.1093/jac/dkh465
14. Kim HJ, Jones MN (2004) The delivery of benzyl penicillin to Staphylococcus aureus biofilms by use of liposomes. J Liposome Res 14:123-139. doi: 10.1081/LPR-200029887
15. Kim HJ, Michael GE, Jones MN (1999) The adsorption of cationic liposomes to S. aureus biofilms. Colloids Surf A Physicochem Eng Asp 149:561-570
16. Lambe DW Jr, Ferguson KP, Mayberry-Carson KJ, Tober-Meyer B, Costerton JW (1991) Foreign-body-associated experimental osteomyelitis induced with Bacteroides fragilis and Staphylococcus epidermidis in rabbits. Clin Orthop Relat Res 266:285-294
17. Matl FD, Obermeier A, Repmann S, Friess W, Stemberger A, Kuehn KD (2008) New anti-infective coatings of medical implants based on lipid-like drug carriers. Antimicrob Agents Chemother (Epub ahead of print)
18. Moghimi SM, Porter CJ, Illum L, Davis SS (1991) The effect of poloxamer-407 on liposome stability and targeting to bone marrow: comparison with polystyrene microspheres. Int J Pharm 68:121-126. doi: 10.1016/0378-5173(91)90134-A
19. Morgan JR, Williams KE (1980) Preparation and properties of liposome-associated gentamicin. Antimicrob Agents Chemother 17:544-548
20. Norden CW (1971) Experimental osteomyelitis. II. Therapeutic trials and measurement of antibiotic levels in bone. J Infect Dis 124:565-571
21. Norden CW (1975) Experimental osteomyelitis. IV. Therapeutic trials with rifampin alone and in combination with gentamicin, sisomicin, and cephalothin. J Infect Dis 132:493-499
22. Norden CW (1983) Experimental chronic staphylococcal osteomyelitis in rabbits: Treatment with rifampin alone and in combination with other antimicrobial agents. Rev Infect Dis 5:S491-S494
23. Norden CW, Keleti E (1980) Treatment of experimental staphylococcal osteomyelitis with rifampin and trimethoprim, alone and in combination. Antimicrob Agents Chemother 17:591-594
24. Norden CW, Keleti E (1980) Experimental osteomyelitis caused by Pseudomonas aeruginosa. J Infect Dis 141:71-75
25. Norden CW, Shaffer M (1983) Treatment of experimental chronic osteomyelitis due to S. aureus with gentamicin and rifampin. J Infect Dis 147:352-357
26. Norden CW, Shinners E (1985) Ciprofloxacin as therapy for experimental osteomyelitis caused by Pseudomonas aeruginosa. J Infect Dis 151:291-294
27. Norden CW, Shinners E, Niederriter K (1986) Clindamycin treatment of experimental chronic osteomyelitis due to S. aureus. J Infect Dis 153:956-959
28. Power ME, Olson ME, Domingue PA, Costerton JW (1990) A rat model of S. aureus chronic osteomyelitis that provides a suitable system for studying the human infection. J Med Microbiol 33:189-198
29. Ravaoarinoro M, Toma E, Agbaba O, Morisset R (1993) Efficient entrapment of amikacin and teicoplanin in liposomes. J Drug Target 1:191-195. doi: 10.3109/10611869308996076
30. Schafer JA, Hovde LB, Rotschafer JC (2006) Consistent rates of kill of Staphylococcus aureus by gentamicin over a 6-fold clinical concentration range in an in vitro pharmacodynamic model (IVPDM). J Antimicrob Chemother 58:108-111. doi: 10.1093/jac/dkl216
31. Schiffelers R, Storm G, Bakker-Woudenberg I (2001) Liposome-encapsulated aminoglycosides in pre-clinical and clinical studies. J Antimicrob Chemother 48:333-344. doi: 10.1093/jac/48.3.333
32. Spagnolo N, Greco F, Rossi A, Ciolli L, Teti A, Posteraro P (1993) Chronic staphylococcal osteomyelitis: A new experimental rat model. Infect Immun 61:5225-5230
33. Stallmann HP, Faber C, Slotema ET, Lyaruu DM, Bronckers AL, Amerongen AV, Wuisman PI (2003) Continuous-release or burst-release of the antimicrobial peptide human lactoferrin 1-11 (hLF1-11) from calcium phosphate bone substitutes. J Antimicrob Chemother 52:853-855. doi: 10.1093/jac/dkg443