Evaluation of Mdh1 protein as an antigenic candidate for a vaccine against candidiasis

Biocontrol Science

Volumn 19, Issue 1, 2014, Pages 51-55

  Shibasaki, Seiji ^a   Aoki, Wataru ^b   Nomura, Takashi ^c   Karasaki, Miki ^a   Sewaki, Tomomitsu ^c   Ueda, Mitsuyoshi ^b  

^a HYOGO COLLEGE OF MEDICINE   (Japan)

^b KYOTO UNIVERSITY   (Japan)

^c Genolac BL Corporation Okinawa Industry Support Center 4F   (Japan)

Author keywords

Candida albicans; Candidiasis; Mdh1p; Vaccine

Indexed keywords

ANTIGENS; CANDIDA; ESCHERICHIA COLI; MAMMALS; RECOMBINANT PROTEINS; YEAST;

ANTIBODY RESPONSE; CANDIDA ALBICANS; CANDIDIASIS; INTRANASAL; LETHAL DOSE; MALATE DEHYDROGENASE; MDH1P; SURVIVAL TESTS;

VACCINES;

CANDIDA ALBICANS VACCINE; CHOLERA TOXIN; FREUND ADJUVANT; FUNGUS ANTIGEN; HYBRID PROTEIN; MALATE DEHYDROGENASE; RECOMBINANT DNA; RECOMBINANT PROTEIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIBODY RESPONSE; ANTIBODY TITER; ARTICLE; CANDIDA ALBICANS; CANDIDIASIS; CONTROLLED STUDY; DRUG ANTIGENICITY; ESCHERICHIA COLI; FEMALE; FUNGAL GENOME; IMMUNE RESPONSE; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; SURVIVAL; VACCINATION; VACCINE PRODUCTION;

ANIMALS; ANTIBODIES, FUNGAL; CANDIDA ALBICANS; CANDIDIASIS; DRUG EVALUATION, PRECLINICAL; FEMALE; FUNGAL PROTEINS; FUNGAL VACCINES; HUMANS; MALATE DEHYDROGENASE; MICE; MICE, INBRED C57BL; VACCINATION;

EID: 84897562532     PISSN: 13424815     EISSN: 18840205     Source Type: Journal    
DOI: 10.4265/bio.19.51     Document Type: Article

References (18)

1. Aoki, W., Kitahara, N., Miura, N., Morisaka, H., Yamamoto, Y., Kuroda, K., and Ueda, M.(2011) Comprehensive characterization of secreted aspartic proteases encoded by a virulence gene family in Candida albicans. J. Biochem., 150, 431-438.
2. Aoki, W., Ueda, T., Tatsukami, Y., Kitahara, N., Morisaka, H., Kuroda, K., and Ueda, M. (2013) Time-course proteomic profile of Candida albicans during adaptation to a fetal serum. Pathog. Dis., 67, 67-75.
3. Brown, A.J., Odds, F.C., and Gow, N.A. (2007) Infection-related gene expression in Candida albicans. Curr. Opin. Microbiol., 10, 307-313.
4. Fernández-Arenas, E., Molero, G., Nombela, C., Diez-Orejas, R, and Gil C. (2004) Low virulent strains of Candida albicans: unravelling the antigens for a future vaccine. Proteomics, 4, 3007-3020.
5. Hanahan, D. (1983) Studies on transformation of Escherichia coli with plasmids. J. Mol. Biol., 166, 557-580.
6. Heilmann, C.J., Sorgo, A.G., Siliakus, A.R., Dekker, H.L., Brul, S., de Koster, C.G., de Koning, L.J., and Klis, F.M. (2011) Hyphal induction in the human fungal pathogen Candida albicans reveals a characteristic wall protein profile. Microbiology, 157, 2297-2307.
7. Inaoka, T., Matsumura, Y., and Tsuchido, T. (1999) Metal-mediated control of the activity of Bacillus subtilis superoxide dismutase. Biocontrol. Sci., 4, 55-58.
8. Luo, G., Ibrahim, A.S., Spellberg, B., Nobile, C.J., Mitchell, A.P., and Fu, Y. (2010) Candida albicans Hyr1p confers resistance to neutrophil killing and is a potential vaccine target. J. Infect. Dis., 201, 1718-1728.
9. Matsumura, K., Furukawa, S., Ogihara, H., and Morinaga, Y. (2011) Roles of multidrug efflux pumps on the biofilm formation of Escherichia coli K-12. Biocontrol. Sci., 16, 69-72.
10. Morschhauser, J. (2002) The genetic basis of fluconazole resistance development in Candida albicans. Biochim. Biophys. Acta., 1587, 240-248.
11. Pfaller, M.A., and Diekema, D.J. (2007) Epidemiology of invasive candidiasis: a persistent public health problem. Clin. Microbiol. Rev., 20, 133-163.
12. Rodloff, C., Koch, D., and Schaumann, R. (2011) Epidemiology and antifungal resistance in invasive candidiasis. Eur. J. Med. Res., 16, 187-195.
13. Shibasaki, S., Kawabata, A., Tanino, T., Kondo, A., Ueda, M., and Tanaka, M. (2009) Evaluation of the biodegradability of polyurethane and its derivatives by using lipase-displaying arming yeast. Biocontrol. Sci., 14, 171-175.
14. Shibasaki, S., and Ueda, M. (2010) Development of yeast molecular display systems focused on therapeutic proteins, enzymes, and foods: functional analysis of proteins and its application to bioconversion. Recent Pat. Biotechnol., 4, 198-213.
15. Suido, El., and Miyao, M. (2008) Bifidobacterium longum-fermented broccoli supernatant inhibited the growth of Candida albicans and some pathogenic bacteria in vitro. Biocontrol. Sci., 13, 41-48.
16. Tamaru, Y., Ohtsuka, M., Kato, K., Manabe, S., Kuroda, K., Sanada, M., and Ueda, M. (2006) Application of the arming system for the expression of the 380R antigen from red sea bream iridovirus (RSIV) on the surface of yeast cells: a first step for the development of an oral vaccine. Biotechnol. Prog., 22, 949-953.
17. Xin, H., and Cutler, J.E. (2011) Vaccine and monoclonal antibody that enhance mouse resistance to candidiasis. Clin. Vaccine. Immunol., 18, 1656-1667.
18. Zaoutis, T. E., Argon, J., Chu, J., Berlin, J. A., Walsh, T. J., and Feudtner, C. (2005) The epidemiology and attributable outcomes of candidemia in adults and children hospitalized in the United States: a propensity analysis. Clin. Infect. Dis., 41, 1232-1239.