Pros and cons of phospholipid asymmetry in erythrocytes

Journal of Pharmacy and Bioallied Sciences

Volumn 6, Issue 2, 2014, Pages 81-85

  Sathi, Aiswarya ^a   Viswanad, Vidya ^a   Aneesh, T P ^a   Kumar, B Anil ^a  

^a AMRITA INSTITUTE OF MEDICAL SCIENCES   (India)

Author keywords

Erythrocytes; lipid asymmetry; phosphatidyl serine; phospholipids

Indexed keywords

CALCIUM; CARRIER PROTEIN; DRUG CARRIER; FLIPPASE; FLOPPASE; LIPOCORTIN 5; PHOSPHOLIPID; SCRAMBLASE; SPECTRIN; UNCLASSIFIED DRUG;

BETA THALASSEMIA; BINDING AFFINITY; BINDING SITE; BIOLOGICAL PHENOMENA AND FUNCTIONS CONCERNING ORGAN SYSTEMS; BLOOD CLOTTING; BLOOD VESSEL OCCLUSION; CELL TRANSPORT; CHRONIC MYELOID LEUKEMIA; CONFOCAL MICROSCOPY; DISEASE ACTIVITY; ENZYME ACTIVITY; ENZYME ASSAY; ERYTHROCYTE; FLUORESCENCE ACTIVATED CELL SORTING; FLUORESCENCE ANALYSIS; HUMAN; HYPERBILIRUBINEMIA; IN VITRO STUDY; INFLAMMATION; LIPID ANALYSIS; MACROPHAGE; MOLECULAR DYNAMICS; MOLECULAR PATHOLOGY; MONONUCLEAR PHAGOCYTE; PHOSPHOLIPID ASYMMETRY; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN FUNCTION; PROTEIN LOCALIZATION; RETICULOENDOTHELIAL SYSTEM; REVIEW; SICKLE CELL ANEMIA; UREMIA;

EID: 84897554649     PISSN: None     EISSN: 09757406     Source Type: Journal    
DOI: 10.4103/0975-7406.129171     Document Type: Review

References (29)

1. Antony GL. Structure and function of cell membranes. In: John BT, editor. Comprehensive Medicinal Chemistry. Delhi: Elsevier Publication; 2005. p. 13-43
2. Daleke DL. Regulation of phospholipid asymmetry in the erythrocyte membrane. Curr Opin Hematol 2008;15:191-5
3. Sugihara T, Sugihara K, Hebbel RP. Phospholipid asymmetry during erythrocyte deformation: Maintenance of the unit membrane. Biochim Biophys Acta 1992;1103:303-6
4. Bitbol M, Fellmann P, Zachowski A, Devaux PF. Ion regulation of phosphatidylserine and phosphatidylethanolamine outside-inside translocation in human erythrocytes. Biochim Biophys Acta 1987;904:268-82
5. Manno S, Takakuwa Y, Mohandas N. Identification of a functional role for lipid asymmetry in biological membranes: Phosphatidylserine-skeletal protein interactions modulate membrane stability. Proc Natl Acad Sci U S A 2002;99:1943-8
6. Schroeder F. Role of membrane lipid asymmetry in aging. Neurobiol Aging 1984;5:323-33
7. Fadok VA, de Cathelineau A, Daleke DL, Henson PM, Bratton DL. Loss of phospholipid asymmetry and surface exposure of phosphatidylserine is required for phagocytosis of apoptotic cells by macrophages and fibroblasts. J Biol Chem 2001;276:1071-7
8. Kong QY, Wu X, Li J, Peng WX, Ye R, Lindholm B, et al. Loss of phospholipids asymmetry in red blood cells contributes to anemia in uremic patients. Adv Perit Dial 2001;17:58-60
9. Bonomini M, Sirolli V, Settefrati N, Dottori S, Di Liberato L, Arduini A. Increased erythrocyte phosphatidylserine exposure in chronic renal failure. J Am Soc Nephrol 1999;10:1982-90
10. Williamson P, Algarin L, Bateman J, Choe HR, Schlegel RA. Phospholipid asymmetry in human erythrocyte ghosts. J Cell Physiol 1985;123:209-14
11. Connor J, Gillum K, Schroit AJ. Maintenance of lipid asymmetry in red blood cells and ghosts: Effect of divalent cations and serum albumin on the transbilayer distribution of phosphatidylserine. Biochim Biophys Acta 1990;1025:82-6
12. Mehrdad H, Mahshid F, Abdolhossein Z, Ahmadreza M. Erythrocytes: From oxygen delivery to drug delivery. Control Release J 2012;1:1-33
13. Setty BN, Betal SG. Microvascular endothelial cells express a phosphatidylserine receptor: A functionally active receptor for phosphatidylserine-positive erythrocytes. Blood 2008;111:905-14
14. Lubin B, Chiu D, Bastacky J, Roelofsen B, Van Deenen LL. Abnormalities in membrane phospholipid organization in sickled erythrocytes. J Clin Invest 1981;67:1643-9
15. Blumenfeld N, Zachowski A, Galacteros F, Beuzard Y, Devaux PF. Transmembrane mobility of phospholipids in sickle erythrocytes: Effect of deoxygenation on diffusion and asymmetry. Blood 1991;77:849-54
16. Larson MC, Woodliff JE, Hillery CA, Kearl TJ, Zhao M. Phosphatidylethanolamine is externalized at the surface of microparticles. Biochim Biophys Acta 2012;1821:1501-7
17. Lim KM, Kim S, Noh JY, Kim K, Jang WH, Bae ON, et al. Low-level mercury can enhance procoagulant activity of erythrocytes: A new contributing factor for mercury-related thrombotic disease. Environ Health Perspect 2010;118:928-35
18. Setty BN, Kulkarni S, Rao AK, Stuart MJ. Fetal hemoglobin in sickle cell disease: Relationship to erythrocyte phosphatidylserine exposure and coagulation activation. Blood 2000;96:1119-24
19. Robert AS, Susan K, Patrick W. Functional and pathological significance of phospholipid asymmetry in erythrocyte membranes. J Biosci 1990;15:187-91
20. Kumar A, Daniel S, Agarwal SS, Gupta CM. Abnormal erythrocyte membrane phospholipid organization in chronic myeloid leukemia. J Biosci 1987;11:543-8
21. Reed JA, Kough RH, Williamson PL, Schlegel RA. Merocyanine 540 recognizes membrane abnormalities of erythrocytes in chronic myelogenous leukemia. Cell Biol Int Rep 1985;9:43-9
22. Brito MA, Silva RF, Brites D. Bilirubin induces loss of membrane lipids and exposure of phosphatidylserine in human erythrocytes. Cell Biol Toxicol 2002;18:181-92
23. Zhang X, Inukai T, Hirose K, Akahane K, Nemoto A, Takahashi K, et al. Induction of impaired membrane phospholipid asymmetry in mature erythrocytes after chemotherapy. Int J Hematol 2005;82:132-6
24. Kuypers FA, Yuan J, Lewis RA, Snyder LM, Kiefer CR, Bunyaratvej A, et al. Membrane phospholipid asymmetry in human thalassemia. Blood 1998;91:3044-51
25. Lizarbe MA, Barrasa JI, Olmo N, Gavilanes F, Turnay J. Annexin-phospholipid interactions. Functional implications. Int J Mol Sci 2013;14:2652-83
26. Wang T, Bai J, Jiang X, Nienhaus GU. Cellular uptake of nanoparticles by membrane penetration: A study combining confocal microscopy with FTIR spectroelectrochemistry. ACS Nano 2012;6:1251-9
27. Fatemeh M, Staffan L, Ulo L, Shiroh F, Astrid G. Mechanisms of cellular uptake of cell-penetrating peptides. J Biophys 2011;2011:414729
28. Richard JP, Melikov K, Vives E, Ramos C, Verbeure B, Gait MJ, et al. Cell-penetrating peptides. A reevaluation of the mechanism of cellular uptake. J Biol Chem 2003;278:585-90
29. van der Meer PF, Cancelas JA, Cardigan R, Devine DV, Gulliksson H, Sparrow RL, et al. Evaluation of overnight hold of whole blood at room temperature before component processing: Effect of red blood cell (RBC) additive solutions on in vitro RBC measures. Transfusion 2011;51 Suppl 1:15S-24