Dysregulation of ubiquitin homeostasis and β-catenin signaling promote spinal muscular atrophy

Journal of Clinical Investigation

Volumn 124, Issue 4, 2014, Pages 1821-1834

  Wishart, Thomas M ^a,b   Mutsaers, Chantal A ^a   Riessland, Markus ^c   Reimer, Michell M ^a   Hunter, Gillian ^a   Hannam, Marie L ^d   Eaton, Samantha L ^b   Fuller, Heidi R ^e,f   Roche, Sarah L ^a   Somers, Eilidh ^a   Morse, Robert ^g   Young, Philip J ^g   Lamont, Douglas J ^h   Hammerschmidt, Matthias ^c   Joshi, Anagha ^b   Hohenstein, Peter ^b   Morris, Glenn E ^e,f   Parson, Simon H ^a,i   Skehel, Paul A ^a   Becker, Thomas ^a   Robinson, Iain M ^d   Becker, Catherina G ^a   Wirth, Brunhilde ^c   Gillingwater, Thomas H ^a   more..

^a UNIVERSITY OF EDINBURGH   (United Kingdom)

^b UNIVERSITY OF EDINBURGH   (United Kingdom)

^c UNIVERSITY OF COLOGNE   (Germany)

^d PENINSULA MEDICAL SCHOOL   (United Kingdom)

^e ROBERT JONES AND AGNES HUNT ORTHOPAEDIC HOSPITAL   (United Kingdom)

^f KEELE UNIVERSITY   (United Kingdom)

^g UNIVERSITY OF EXETER   (United Kingdom)

^h UNIVERSITY OF DUNDEE   (United Kingdom)

ⁱ UNIVERSITY OF ABERDEEN   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

BETA CATENIN; MESSENGER RNA; QUERCETIN; SURVIVAL MOTOR NEURON PROTEIN; UBIQUITIN; UBIQUITIN LIKE MODIFIER ACTIVATING ENZYME 1; UBIQUITIN PROTEIN LIGASE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DROSOPHILA; DRUG DOSE INCREASE; ENZYME REPRESSION; GENE DISRUPTION; GENE REPRESSION; MOLECULAR PATHOLOGY; MOUSE; NERVE CELL; NEUROMUSCULAR SYSTEM; NONHUMAN; PRIORITY JOURNAL; PROTEIN HOMEOSTASIS; PROTEIN PROTEIN INTERACTION; RNA SPLICING; SIGNAL TRANSDUCTION; SPINAL CORD; SPINAL MUSCULAR ATROPHY; UBIQUITINATION; ZEBRA FISH;

ALTERNATIVE SPLICING; ANIMALS; BETA CATENIN; DISEASE MODELS, ANIMAL; DROSOPHILA; HOMEOSTASIS; HUMANS; ISOENZYMES; MICE; MICE, KNOCKOUT; MICE, MUTANT STRAINS; MICE, TRANSGENIC; MUSCLE, SKELETAL; MUSCULAR ATROPHY, SPINAL; RATS; RNA, MESSENGER; SIGNAL TRANSDUCTION; SPINAL CORD; SURVIVAL OF MOTOR NEURON 1 PROTEIN; UBIQUITIN; UBIQUITIN-ACTIVATING ENZYMES; ZEBRAFISH;

EID: 84897548490     PISSN: 00219738     EISSN: 15588238     Source Type: Journal    
DOI: 10.1172/JCI71318     Document Type: Article

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