Major Facilitator Superfamily (MFS) evolved without 3-transmembrane segment unit rearrangements

Proceedings of the National Academy of Sciences of the United States of America

Volumn 111, Issue 13, 2014, Pages

  Västermark, Ake ^a   Saier, Milton H ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

LACTOSE PERMEASE; XYLOSE;

HIDDEN MARKOV MODEL; LETTER; MAJOR FACILITATOR SUPERFAMILY; MICROBIOLOGY; NULL HYPOTHESIS; PRIORITY JOURNAL;

ESCHERICHIA COLI; ESCHERICHIA COLI PROTEINS; EVOLUTION, MOLECULAR; SYMPORTERS;

EID: 84897546618     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1400016111     Document Type: Letter

References (5)

1. Madej MG, Dang S, Yan N, Kaback HR (2013) Evolutionary mixand-match with MFS transporters. Proc Natl Acad Sci USA 110(15): 5870-5874.
2. Vastermark A, Lunt B, Saier M (2014) Major Facilitator Superfamily (MFS) porters, LacY, FucP and XylE of Escherichia coli appear to have evolved positionally dissimilar catalytic residues without rearrangement of 3-TMS repeat units. J Mol Microbiol Biotechnol 24(2):82-90.
3. Madej MG, Kaback HR (2013) Evolutionary mix-and-match with MFS transporters II. Proc Natl Acad Sci USA 110(50):E4831-E4838.
4. Doki S, et al. (2013) Structural basis for dynamic mechanism of proton-coupled symport by the peptide transporter POT. Proc Natl Acad Sci USA 110(28):11343-11348.
5. Pedersen BP, et al. (2013) Crystal structure of a eukaryotic phosphate transporter. Nature 496(7446):533-536.