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Volumn 41, Issue 4, 2014, Pages 285-291

Topical valproic acid increases the hair count in male patients with androgenetic alopecia: A randomized, comparative, clinical feasibility study using phototrichogram analysis

Author keywords

androgenetic alopecia; glycogen synthase kinase 3; hair; valproic acid; Wnt; catenin

Indexed keywords

PLACEBO; VALPROIC ACID; DERMATOLOGICAL AGENT;

EID: 84897544427     PISSN: 03852407     EISSN: 13468138     Source Type: Journal    
DOI: 10.1111/1346-8138.12422     Document Type: Article
Times cited : (42)

References (42)
  • 1
    • 0016771059 scopus 로고
    • Male pattern baldness: Classification and incidence
    • Norwood OT,. Male pattern baldness: classification and incidence. South Med J 1975; 68: 1359-1365.
    • (1975) South Med J , vol.68 , pp. 1359-1365
    • Norwood, O.T.1
  • 2
    • 0026650528 scopus 로고
    • The psychological effects of androgenetic alopecia in men
    • Cash TF,. The psychological effects of androgenetic alopecia in men. J Am Acad Dermatol 1992; 26: 926-931.
    • (1992) J Am Acad Dermatol , vol.26 , pp. 926-931
    • Cash, T.F.1
  • 3
    • 0031975932 scopus 로고    scopus 로고
    • Balding hair follicle dermal papilla cells contain higher levels of androgen receptors than those from non-balding scalp
    • Hibberts N,. Balding hair follicle dermal papilla cells contain higher levels of androgen receptors than those from non-balding scalp. J Endocrinol 1998; 156: 59-65.
    • (1998) J Endocrinol , vol.156 , pp. 59-65
    • Hibberts, N.1
  • 4
    • 77955292679 scopus 로고    scopus 로고
    • Efficacy, safety, and tolerability of dutasteride 0.5 mg once daily in male patients with male pattern hair loss: A randomized, double-blind, placebo-controlled, phase III study
    • Eun HC, Kwon OS, Yeon JH, et al,. Efficacy, safety, and tolerability of dutasteride 0.5 mg once daily in male patients with male pattern hair loss: a randomized, double-blind, placebo-controlled, phase III study. J Am Acad Dermatol 2010; 63: 252-258.
    • (2010) J Am Acad Dermatol , vol.63 , pp. 252-258
    • Eun, H.C.1    Kwon, O.S.2    Yeon, J.H.3
  • 5
    • 38149041638 scopus 로고    scopus 로고
    • Dihydrotestosterone-inducible dickkopf 1 from balding dermal papilla cells causes apoptosis in follicular keratinocytes
    • Kwack MH, Sung YK, Chung EJ, et al,. Dihydrotestosterone-inducible dickkopf 1 from balding dermal papilla cells causes apoptosis in follicular keratinocytes. J Invest Dermatol 2008; 128: 262-269.
    • (2008) J Invest Dermatol , vol.128 , pp. 262-269
    • Kwack, M.H.1    Sung, Y.K.2    Chung, E.J.3
  • 6
    • 65249158612 scopus 로고    scopus 로고
    • Keratinocyte growth inhibition through the modification of Wnt signaling by androgen in balding dermal papilla cells
    • Kitagawa T, Matsuda K, Inui S, et al,. Keratinocyte growth inhibition through the modification of Wnt signaling by androgen in balding dermal papilla cells. J Clin Endocrinol Metab 2009; 94: 1288-1294.
    • (2009) J Clin Endocrinol Metab , vol.94 , pp. 1288-1294
    • Kitagawa, T.1    Matsuda, K.2    Inui, S.3
  • 7
    • 84860320828 scopus 로고    scopus 로고
    • Hair follicle stem cell differentiation is inhibited through a cross talk between Wnt/β-catenin and androgen signalling in dermal papilla cells from patients with androgenetic alopecia
    • Leirõs G, Attorresi A, Balañá M,. Hair follicle stem cell differentiation is inhibited through a cross talk between Wnt/β-catenin and androgen signalling in dermal papilla cells from patients with androgenetic alopecia. Br J Dermatol 2012; 166: 1035-1042.
    • (2012) Br J Dermatol , vol.166 , pp. 1035-1042
    • Leirõs, G.1    Attorresi, A.2    Balañá, M.3
  • 8
    • 0036178229 scopus 로고    scopus 로고
    • Molecular mechanisms regulating hair follicle development
    • Millar SE,. Molecular mechanisms regulating hair follicle development. J Invest Dermatol 2002; 118: 216-225.
    • (2002) J Invest Dermatol , vol.118 , pp. 216-225
    • Millar, S.E.1
  • 9
    • 1442323632 scopus 로고    scopus 로고
    • Wnt signaling through the β-catenin pathway is sufficient to maintain, but not restore, anagen-phase characteristics of dermal papilla cells
    • Shimizu H, Morgan BA,. Wnt signaling through the β-catenin pathway is sufficient to maintain, but not restore, anagen-phase characteristics of dermal papilla cells. J Invest Dermatol 2004; 122: 239-245.
    • (2004) J Invest Dermatol , vol.122 , pp. 239-245
    • Shimizu, H.1    Morgan, B.A.2
  • 10
    • 67651158849 scopus 로고    scopus 로고
    • Inhibition of glycogen synthase kinase-3 enhances the expression of alkaline phosphatase and insulin-like growth factor-1 in human primary dermal papilla cell culture and maintains mouse hair bulbs in organ culture
    • Yamauchi K, Kurosaka A,. Inhibition of glycogen synthase kinase-3 enhances the expression of alkaline phosphatase and insulin-like growth factor-1 in human primary dermal papilla cell culture and maintains mouse hair bulbs in organ culture. Arch Dermatol Res 2009; 301: 357-365.
    • (2009) Arch Dermatol Res , vol.301 , pp. 357-365
    • Yamauchi, K.1    Kurosaka, A.2
  • 11
    • 0034257051 scopus 로고    scopus 로고
    • Mechanisms of action of valproate: A commentatory
    • Johannessen CU,. Mechanisms of action of valproate: a commentatory. Neurochem Int 2000; 37: 103-110.
    • (2000) Neurochem Int , vol.37 , pp. 103-110
    • Johannessen, C.U.1
  • 12
    • 0036401554 scopus 로고    scopus 로고
    • Pharmacological and therapeutic properties of valproate: A summary after 35 years of clinical experience
    • Perucca E,. Pharmacological and therapeutic properties of valproate: a summary after 35 years of clinical experience. CNS Drugs 2002; 16: 695-714.
    • (2002) CNS Drugs , vol.16 , pp. 695-714
    • Perucca, E.1
  • 13
    • 28144456841 scopus 로고    scopus 로고
    • Mode of action: Inhibition of histone deacetylase, altering WNT-dependent gene expression, and regulation of beta-catenin-developmental effects of valproic acid
    • Wiltse J,. Mode of action: inhibition of histone deacetylase, altering WNT-dependent gene expression, and regulation of beta-catenin-developmental effects of valproic acid. Crit Rev Toxicol 2005; 35: 727-738.
    • (2005) Crit Rev Toxicol , vol.35 , pp. 727-738
    • Wiltse, J.1
  • 14
    • 5144226319 scopus 로고    scopus 로고
    • Examining the correlations between GSK-3 inhibitory properties and anti-convulsant efficacy of valproate and valproate-related compounds
    • Werstuck GH, Kim AJ, Brenstrum T, Ohnmacht SA, Panna E, Capretta A,. Examining the correlations between GSK-3 inhibitory properties and anti-convulsant efficacy of valproate and valproate-related compounds. Bioorg Med Chem Lett 2004; 14: 5465-5467.
    • (2004) Bioorg Med Chem Lett , vol.14 , pp. 5465-5467
    • Werstuck, G.H.1    Kim, A.J.2    Brenstrum, T.3    Ohnmacht, S.A.4    Panna, E.5    Capretta, A.6
  • 15
    • 35248894933 scopus 로고    scopus 로고
    • The mechanisms of action of valproate in neuropsychiatric disorders: Can we see the forest for the trees?
    • Rosenberg G,. The mechanisms of action of valproate in neuropsychiatric disorders: can we see the forest for the trees? Cell Mol Life Sci 2007; 64: 2090-2103.
    • (2007) Cell Mol Life Sci , vol.64 , pp. 2090-2103
    • Rosenberg, G.1
  • 16
    • 0036311668 scopus 로고    scopus 로고
    • Valproate regulates GSK-3-mediated axonal remodeling and synapsin i clustering in developing neurons
    • Hall AC, Brennan A, Goold RG, et al,. Valproate regulates GSK-3-mediated axonal remodeling and synapsin I clustering in developing neurons. Mol Cell Neurosci 2002; 20: 257-270.
    • (2002) Mol Cell Neurosci , vol.20 , pp. 257-270
    • Hall, A.C.1    Brennan, A.2    Goold, R.G.3
  • 17
    • 84883817133 scopus 로고    scopus 로고
    • Valproic acid promotes human hair growth in in vitro culture model
    • Jo SJ, Choi SJ, Yoon SY, et al,. Valproic acid promotes human hair growth in in vitro culture model. J Dermatol Sci 2013; 72: 16-24.
    • (2013) J Dermatol Sci , vol.72 , pp. 16-24
    • Jo, S.J.1    Choi, S.J.2    Yoon, S.Y.3
  • 18
    • 84859604498 scopus 로고    scopus 로고
    • Valproic acid induces hair regeneration in murine model and activates alkaline phosphatase activity in human dermal papilla cells
    • Lee SH, Yoon J, Shin SH, et al,. Valproic acid induces hair regeneration in murine model and activates alkaline phosphatase activity in human dermal papilla cells. PLoS One 2012; 7: e34152.
    • (2012) PLoS One , vol.7
    • Lee, S.H.1    Yoon, J.2    Shin, S.H.3
  • 19
    • 0842325787 scopus 로고    scopus 로고
    • Histone deacetylase is a target of valproic acid-mediated cellular differentiation
    • Gurvich N,. Histone deacetylase is a target of valproic acid-mediated cellular differentiation. Cancer Res 2004; 64: 1079-1086.
    • (2004) Cancer Res , vol.64 , pp. 1079-1086
    • Gurvich, N.1
  • 20
    • 0035965343 scopus 로고    scopus 로고
    • Histone deacetylase is a direct target of valproic acid, a potent anticonvulsant, mood stabilizer, and teratogen
    • Phiel CJ, Zhang F, Huang EY, Guenther MG, Lazar MA, Klein PS,. Histone deacetylase is a direct target of valproic acid, a potent anticonvulsant, mood stabilizer, and teratogen. J Biol Chem 2001; 276: 36734-36741.
    • (2001) J Biol Chem , vol.276 , pp. 36734-36741
    • Phiel, C.J.1    Zhang, F.2    Huang, E.Y.3    Guenther, M.G.4    Lazar, M.A.5    Klein, P.S.6
  • 21
    • 0036721055 scopus 로고    scopus 로고
    • Anti-tumor mechanisms of valproate: A novel role for an old drug
    • Blaheta RA, Cinatl J Jr,. Anti-tumor mechanisms of valproate: a novel role for an old drug. Med Res Rev 2002; 22: 492-511.
    • (2002) Med Res Rev , vol.22 , pp. 492-511
    • Blaheta, R.A.1    Cinatl, Jr.J.2
  • 22
    • 0141644176 scopus 로고    scopus 로고
    • Multiple congenital malformations including generalized hypertrichosis with gum hypertrophy in a child exposed to valproic acid in utero
    • Stoll C, Audeoud F, Gaugler C, Bernardin A, Messer J,. Multiple congenital malformations including generalized hypertrichosis with gum hypertrophy in a child exposed to valproic acid in utero. Genet Couns 2003; 14: 289-298.
    • (2003) Genet Couns , vol.14 , pp. 289-298
    • Stoll, C.1    Audeoud, F.2    Gaugler, C.3    Bernardin, A.4    Messer, J.5
  • 23
    • 0028045747 scopus 로고
    • Valproic acid. A reappraisal of its pharmacological properties and clinical efficacy in epilepsy
    • Davis R, Peters DH, McTavish D,. Valproic acid. A reappraisal of its pharmacological properties and clinical efficacy in epilepsy. Drugs 1994; 47: 332-372.
    • (1994) Drugs , vol.47 , pp. 332-372
    • Davis, R.1    Peters, D.H.2    McTavish, D.3
  • 27
    • 67349219165 scopus 로고    scopus 로고
    • The effects of biotin supplementation on serum and liver tissue biotinidase enzyme activity and alopecia in rats which were administrated to valproic acid
    • Arslan M, Vurucu S, Balamtekin N, et al,. The effects of biotin supplementation on serum and liver tissue biotinidase enzyme activity and alopecia in rats which were administrated to valproic acid. Brain Dev 2009; 31: 405-410.
    • (2009) Brain Dev , vol.31 , pp. 405-410
    • Arslan, M.1    Vurucu, S.2    Balamtekin, N.3
  • 29
    • 0025022511 scopus 로고
    • Low biotinidase activities in the sera of patients with impaired liver function: Evidence that the liver is the source of serum biotinidase
    • Grier RE, Heard GS, Watkins P, Wolf B,. Low biotinidase activities in the sera of patients with impaired liver function: evidence that the liver is the source of serum biotinidase. Clin Chim Acta 1990; 186: 397-400.
    • (1990) Clin Chim Acta , vol.186 , pp. 397-400
    • Grier, R.E.1    Heard, G.S.2    Watkins, P.3    Wolf, B.4
  • 30
    • 68349113676 scopus 로고    scopus 로고
    • The influence of valproic acid treatment on hair and serum zinc levels and serum biotinidase activity
    • Yilmaz Y, Tasdemir HA, Paksu MS,. The influence of valproic acid treatment on hair and serum zinc levels and serum biotinidase activity. Eur J Paediatr Neurol 2009; 13: 439-443.
    • (2009) Eur J Paediatr Neurol , vol.13 , pp. 439-443
    • Yilmaz, Y.1    Tasdemir, H.A.2    Paksu, M.S.3
  • 31
    • 0031683562 scopus 로고    scopus 로고
    • Finasteride in the treatment of men with androgenetic alopecia. Finasteride Male Pattern Hair Loss Study Group
    • Kaufman KD, Olsen EA, Whiting D, et al,. Finasteride in the treatment of men with androgenetic alopecia. Finasteride Male Pattern Hair Loss Study Group. J Am Acad Dermatol 1998; 39: 578-589.
    • (1998) J Am Acad Dermatol , vol.39 , pp. 578-589
    • Kaufman, K.D.1    Olsen, E.A.2    Whiting, D.3
  • 32
    • 0023107896 scopus 로고
    • Use of topical minoxidil in the treatment of male pattern baldness
    • Savin RC,. Use of topical minoxidil in the treatment of male pattern baldness. J Am Acad Dermatol 1987; 16: 696-704.
    • (1987) J Am Acad Dermatol , vol.16 , pp. 696-704
    • Savin, R.C.1
  • 34
    • 0025967573 scopus 로고
    • Seasonal changes in human hair growth
    • Randall VA, Ebling FJ,. Seasonal changes in human hair growth. Br J Dermatol 1991; 124: 146-151.
    • (1991) Br J Dermatol , vol.124 , pp. 146-151
    • Randall, V.A.1    Ebling, F.J.2
  • 35
    • 16844379225 scopus 로고    scopus 로고
    • Severe valproic acid intoxication is associated with atrial tachycardia: Secondary detoxication by hemoperfusion
    • Meyer S, Kuhlmann MK, Peters FT, Limbach HG, Lindinger A,. Severe valproic acid intoxication is associated with atrial tachycardia: secondary detoxication by hemoperfusion. Klin Padiatr 2005; 217: 82-85.
    • (2005) Klin Padiatr , vol.217 , pp. 82-85
    • Meyer, S.1    Kuhlmann, M.K.2    Peters, F.T.3    Limbach, H.G.4    Lindinger, A.5
  • 36
    • 0018959587 scopus 로고
    • Valproic acid in childhood epilepsy: Anticonvulsive efficacy in relation to its plasma levels
    • Klotz U, Schweizer C,. Valproic acid in childhood epilepsy: anticonvulsive efficacy in relation to its plasma levels. Int J Clin Pharmacol Ther Toxicol 1980; 18: 461-465.
    • (1980) Int J Clin Pharmacol Ther Toxicol , vol.18 , pp. 461-465
    • Klotz, U.1    Schweizer, C.2
  • 37
    • 68749093201 scopus 로고    scopus 로고
    • Randomized clinical trial comparing 5% and 1% topical minoxidil for the treatment of androgenetic alopecia in Japanese men
    • Tsuboi R, Arano O, Nishikawa T, Yamada H, Katsuoka K,. Randomized clinical trial comparing 5% and 1% topical minoxidil for the treatment of androgenetic alopecia in Japanese men. J Dermatol 2009; 36: 437-446.
    • (2009) J Dermatol , vol.36 , pp. 437-446
    • Tsuboi, R.1    Arano, O.2    Nishikawa, T.3    Yamada, H.4    Katsuoka, K.5
  • 38
    • 35148828103 scopus 로고    scopus 로고
    • Efficacy of 5% minoxidil versus combined 5% minoxidil and 0.01% tretinoin for male pattern hair loss: A randomized, double-blind, comparative clinical trial
    • Shin HS, Won CH, Lee SH, Kwon OS, Kim KH, Eun HC,. Efficacy of 5% minoxidil versus combined 5% minoxidil and 0.01% tretinoin for male pattern hair loss: a randomized, double-blind, comparative clinical trial. Am J Clin Dermatol 2007; 8: 285-290.
    • (2007) Am J Clin Dermatol , vol.8 , pp. 285-290
    • Shin, H.S.1    Won, C.H.2    Lee, S.H.3    Kwon, O.S.4    Kim, K.H.5    Eun, H.C.6
  • 39
    • 33847713689 scopus 로고    scopus 로고
    • A randomized, placebo-controlled trial of 1% topical minoxidil solution in the treatment of androgenetic alopecia in Japanese women
    • Tsuboi R, Tanaka T, Nishikawa T, et al,. A randomized, placebo-controlled trial of 1% topical minoxidil solution in the treatment of androgenetic alopecia in Japanese women. Eur J Dermatol 2007; 17: 37-44.
    • (2007) Eur J Dermatol , vol.17 , pp. 37-44
    • Tsuboi, R.1    Tanaka, T.2    Nishikawa, T.3
  • 40
    • 35148886772 scopus 로고    scopus 로고
    • A multicenter, randomized, placebo-controlled, double-blind clinical trial of a novel formulation of 5% minoxidil topical foam versus placebo in the treatment of androgenetic alopecia in men
    • Olsen EA, Whiting D, Bergfeld W, et al,. A multicenter, randomized, placebo-controlled, double-blind clinical trial of a novel formulation of 5% minoxidil topical foam versus placebo in the treatment of androgenetic alopecia in men. J Am Acad Dermatol 2007; 57: 767-774.
    • (2007) J Am Acad Dermatol , vol.57 , pp. 767-774
    • Olsen, E.A.1    Whiting, D.2    Bergfeld, W.3
  • 41
    • 0036737739 scopus 로고    scopus 로고
    • A randomized clinical trial of 5% topical minoxidil versus 2% topical minoxidil and placebo in the treatment of androgenetic alopecia in men
    • Olsen EA, Dunlap FE, Funicella T, et al,. A randomized clinical trial of 5% topical minoxidil versus 2% topical minoxidil and placebo in the treatment of androgenetic alopecia in men. J Am Acad Dermatol 2002; 47: 377-385.
    • (2002) J Am Acad Dermatol , vol.47 , pp. 377-385
    • Olsen, E.A.1    Dunlap, F.E.2    Funicella, T.3


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