Predictors of systemic inflammatory response syndrome in ischemic stroke undergoing systemic thrombolysis with intravenous tissue plasminogen activator

Journal of Stroke and Cerebrovascular Diseases

Volumn 23, Issue 4, 2014, Pages

  Boehme, Amelia K ^a   Kapoor, Niren ^b   Albright, Karen C ^a,c,d   Lyerly, Michael J ^b,e   Rawal, Pawan V ^b   Bavarsad Shahripour, Reza ^b   Alvi, Muhammad ^b   Houston, J Thomas ^b   Sisson, April ^b   Beasley, T Mark ^a   Alexandrov, Anne W ^a,b   Alexandrov, Andrei V ^b   Miller, David W ^f  

^a UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

^b University of Alabama at Birmingham   (United States)

^c Center for Outcomes and Effectiveness Research   (United States)

^d UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

^e BIRMINGHAM VA MEDICAL CENTER   (United States)

^f UNIVERSITY OF ALABAMA SCHOOL OF MEDICINE   (United States)

Author keywords

inflammation; stroke outcome; systemic inflammatory response syndrome; Thrombolysis

Indexed keywords

CHOLESTEROL; TISSUE PLASMINOGEN ACTIVATOR;

ADULT; AFRICAN AMERICAN; AGED; ARTICLE; BODY TEMPERATURE; BRAIN ISCHEMIA; BREATHING RATE; CHOLESTEROL BLOOD LEVEL; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; HEART RATE; HOSPITAL ADMISSION; HOSPITALIZATION; HUMAN; HYPERTENSION; INFECTION; LEUKOCYTE COUNT; MALE; MEDICAL RECORD REVIEW; NEGRO; PREDICTION; PRIORITY JOURNAL; RETROSPECTIVE STUDY; SCORING SYSTEM; STROKE PATIENT; SYSTEMIC INFLAMMATORY RESPONSE SYNDROME;

INFLAMMATION; STROKE OUTCOME; SYSTEMIC INFLAMMATORY RESPONSE SYNDROME; THROMBOLYSIS;

ADMINISTRATION, INTRAVENOUS; ADULT; AGED; AGED, 80 AND OVER; BRAIN ISCHEMIA; FEMALE; FIBRINOLYTIC AGENTS; HUMANS; MALE; MIDDLE AGED; PREDICTIVE VALUE OF TESTS; PREVALENCE; PROGNOSIS; RETROSPECTIVE STUDIES; STROKE; SYSTEMIC INFLAMMATORY RESPONSE SYNDROME; TISSUE PLASMINOGEN ACTIVATOR; YOUNG ADULT;

EID: 84897539566     PISSN: 10523057     EISSN: 15328511     Source Type: Journal    
DOI: 10.1016/j.jstrokecerebrovasdis.2013.11.022     Document Type: Article

References (21)

1. American College of Chest Physicians/Society of Critical Care Medicine Consensus Conference: definitions for sepsis and organ failure and guidelines for the use of innovative therapies in sepsis Crit Care Med 20 1992 864 874
2. G.H. Danton, and W.D. Dietrich Inflammatory mechanisms after ischemia and stroke J Neuropathol Exp Neurol 62 2003 127 136 (Pubitemid 36176947)
3. P.J. Lindsberg, and A.J. Grau Inflammation and infections as risk factors for ischemic stroke Stroke 34 2003 2518 2532 (Pubitemid 37221976)
4. A.L. D'Ambrosio, D.J. Pinsky, and E.S. Connolly The role of the complement cascade in ischemia/reperfusion injury: implications for neuroprotection Mol Med 7 2001 367 382 (Pubitemid 33701972)
5. E.D. Pedersen, U. Waje-Andreassen, and C.A. Vedeler et al. Systemic complement activation following human acute ischaemic stroke Clin Exp Immunol 137 2004 117 122 (Pubitemid 38869785)
6. H.J. Audebert, M.M. Rott, and T. Eck et al. Systemic inflammatory response depends on initial stroke severity but is attenuated by successful thrombolysis Stroke 35 2004 2128 2133 (Pubitemid 39129573)
7. A.D. Kumar, A.K. Boehme, and J.E. Siegler et al. Leukocytosis in patients with neurologic deterioration after acute ischemic stroke is associated with poor outcomes J Stroke Cerebrovasc Dis 22 2013 e111 e117
8. G. Boysen, and H. Christensen Stroke severity determines body temperature in acute stroke Stroke 32 2001 413 417 (Pubitemid 32155227)
9. A.K. Boehme, N. Kapoor, and K.C. Albright et al. Systemic inflammatory response syndrome in tissue-type plasminogen activator-treated patients is associated with worse short-term functional outcome Stroke 44 2013 2321 2323
10. D.J. Muckart, and S. Bhagwanjee American College of Chest Physicians/Society of Critical Care Medicine Consensus Conference definitions of the systemic inflammatory response syndrome and allied disorders in relation to critically injured patients Crit Care Med 25 1997 1789 1795 (Pubitemid 27483955)
11. R. Bender, and S. Lange Adjusting for multiple testing - when and how? J Clin Epidemiol 54 2001 343 349 (Pubitemid 32303457)
12. J.L. Saver, and B. Yafeh Confirmation of tPA treatment effect by baseline severity-adjusted end point reanalysis of the NINDS-tPA stroke trials Stroke 38 2007 414 416 (Pubitemid 46184318)
13. R. Dhar, and M.N. Diringer The burden of the systemic inflammatory response predicts vasospasm and outcome after subarachnoid hemorrhage Neurocrit Care 8 2008 404 412
14. B.R. Gordon, T.S. Parker, and D.M. Levine et al. Relationship of hypolipidemia to cytokine concentrations and outcomes in critically ill surgical patients Crit Care Med 29 2001 1563 1568 (Pubitemid 32762337)
15. B.R. Gordon, T.S. Parker, and D.M. Levine et al. Low lipid concentrations in critical illness: implications for preventing and treating endotoxemia Crit Care Med 24 1996 584 589 (Pubitemid 26133790)
16. X.Z. Ruan, Z. Varghese, and S.H. Powis et al. Dysregulation of LDL receptor under the influence of inflammatory cytokines: a new pathway for foam cell formation Kidney Int 60 2001 1716 1725 (Pubitemid 32999976)
17. H. Gierens, M. Nauck, and M. Roth et al. Interleukin-6 stimulates LDL receptor gene expression via activation of sterol-responsive and Sp1 binding elements Arterioscler Thromb Vasc Biol 20 2000 1777 1783 (Pubitemid 30470593)
18. D.A. Bonville, T.S. Parker, and D.M. Levine et al. The relationships of hypocholesterolemia to cytokine concentrations and mortality in critically ill patients with systemic inflammatory response syndrome Surg Infect (Larchmt) 5 2004 39 49 (Pubitemid 38745054)
19. H.E. Wang, N.I. Shapiro, and R. Griffin et al. Chronic medical conditions and risk of sepsis PLoS One 7 2012 e48307
20. H.E. Wang, R. Griffin, and S. Judd et al. Obesity and risk of sepsis: a population-based cohort study Obesity (Silver Spring) 21 2013 E762 E769
21. E.G. NeSmith, S.P. Weinrich, and J.O. Andrews et al. Demographic differences in systemic inflammatory response syndrome score after trauma Am J Crit Care 21 2012 35 41 quiz 2