Thrombin-induced platelet-fibrin clot strength: Relation to high on-clopidogrel platelet reactivity, genotype, and post-percutaneous coronary intervention outcomes

Thrombosis and Haemostasis

Volumn 111, Issue 4, 2013, Pages 713-724

  Jeong, Young Hoon ^a,b   Bliden, Kevin P ^a   Shuldiner, Alan R ^c   Tantry, Udaya S ^a   Gurbel, Paul A ^a  

^a SINAI CENTER FOR THROMBOSIS RESEARCH   (United States)

^b Gyeongsang National University   (South Korea)

^c UNIVERSITY OF MARYLAND SCHOOL OF MEDICINE   (United States)

Author keywords

Clopidogrel; Clot strength; Cytochrome P450; Percutaneous coronary intervention; Platelet

Indexed keywords

ACETYLSALICYLIC ACID; ACETYLSALICYLIC ACID PLUS CLOPIDOGREL; ADENOSINE DIPHOSPHATE; CLOPIDOGREL; CYTOCHROME P450 2C19; FIBRIN; THROMBIN; TICLOPIDINE;

ADULT; AGED; ARTICLE; CARDIOVASCULAR DISEASE; CARDIOVASCULAR RISK; CLINICAL TRIAL; DRUG ELUTING STENT; FEMALE; FIBRIN CLOT; FOLLOW UP; GENE FREQUENCY; GENOTYPE; GENOTYPING TECHNIQUE; HEMATOLOGICAL PROCEDURE; HEMOSTASIS; HUMAN; LIGHT TRANSMITTANCE AGGREGOMETRY; MAJOR CLINICAL STUDY; MALE; PERCUTANEOUS CORONARY INTERVENTION; PLATELET REACTIVITY; PRIORITY JOURNAL; SINGLE NUCLEOTIDE POLYMORPHISM; THROMBIN INDUCED PLATELET FIBRIN CLOT STRENGTH; THROMBOCYTE AGGREGATION; THROMBOELASTOGRAPHY; ANALOGS AND DERIVATIVES; BLOOD CLOTTING; CARDIOVASCULAR DISEASES; GENETIC POLYMORPHISM; GENETIC SCREENING; GENETICS; METABOLISM; MIDDLE AGED; PHYSIOLOGY; PREDICTIVE VALUE; PROGNOSIS; THROMBOCYTE; TREATMENT OUTCOME;

AGED; ASPIRIN; BLOOD COAGULATION; BLOOD PLATELETS; CARDIOVASCULAR DISEASES; CYTOCHROME P-450 CYP2C19; FEMALE; FIBRIN; GENETIC TESTING; GENOTYPE; HUMANS; MALE; MIDDLE AGED; PERCUTANEOUS CORONARY INTERVENTION; PLATELET AGGREGATION; POLYMORPHISM, GENETIC; PREDICTIVE VALUE OF TESTS; PROGNOSIS; THROMBELASTOGRAPHY; THROMBIN; TICLOPIDINE; TREATMENT OUTCOME;

EID: 84897521869     PISSN: 03406245     EISSN: None     Source Type: Journal    
DOI: 10.1160/TH13-08-0643     Document Type: Article

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