Promoter hypermethylation and suppression of glutathione peroxidase 3 are associated with inflammatory breast carcinogenesis

Oxidative Medicine and Cellular Longevity

Volumn 2014, Issue , 2014, Pages

  Mohamed, Mona M ^a   Sabet, Salwa ^a   Peng, Dun Fa ^b   Nouh, M Akram ^c   El Shinawi, Mohamed ^d   El Rifai, Wael ^b  

^a CAIRO UNIVERSITY   (Egypt)

^b VANDERBILT UNIVERSITY MEDICAL CENTER   (United States)

^c NATIONAL CANCER INSTITUTE   (Egypt)

^d AIN SHAMS UNIVERSITY   (Egypt)

Author keywords

[No Author keywords available]

Indexed keywords

ALKYLATION; DISEASES; ENZYME INHIBITION; GENES; HISTOLOGY; PEPTIDES;

ANTIOXIDANT ENZYME; DISEASE PROGRESSION; EPIGENETIC REGULATION; GLUTATHIONE PEROXIDASE; INFLAMMATORY BREAST CANCERS; INVASIVE DUCTAL CARCINOMATA; PROTEIN EXPRESSION LEVELS; REACTIVE OXYGEN SPECIES;

TISSUE;

GLUTATHIONE PEROXIDASE 3; MESSENGER RNA; GLUTATHIONE PEROXIDASE;

ADULT; ARTICLE; BREAST CARCINOGENESIS; BREAST CARCINOMA; CANCER TISSUE; CLINICAL ARTICLE; CONTROLLED STUDY; DNA METHYLATION; DOWN REGULATION; ENZYME INHIBITION; ENZYME REGULATION; EPIGENETICS; FEMALE; HUMAN; HUMAN TISSUE; INFLAMMATORY BREAST CANCER; PROMOTER REGION; PROTEIN EXPRESSION; BREAST; BREAST TUMOR; ENZYMOLOGY; GENETICS; METABOLISM; MIDDLE AGED; PATHOLOGY;

BREAST; BREAST NEOPLASMS; DNA METHYLATION; DOWN-REGULATION; FEMALE; GLUTATHIONE PEROXIDASE; HUMANS; MIDDLE AGED; PROMOTER REGIONS, GENETIC; RNA, MESSENGER;

EID: 84897521025     PISSN: 19420900     EISSN: 19420994     Source Type: Journal    
DOI: 10.1155/2014/787195     Document Type: Article

References (38)

1. Sipe H. J. Jr., Jordan S. J., Hanna P. M., Mason R. P., The metabolism of 17 β -estradiol lactoperoxidase: a possible source of oxidative stress in breast cancer. Carcinogenesis 1994 15 11 2637 2643 2-s2.0-0028171376
2. Plak K., Czarnecka A. M., Krawczyk T., Golik P., Bartnik E., Breast cancer as a mitochondrial disorder (review). Oncology Reports 2009 21 4 845 851 2-s2.0-67449093464 10.3892/or-00000293
3. Fulton A. M., Chong Y. C., The role of macrophage-derived TNFa in the induction of sublethal tumor cell DNA damage. Carcinogenesis 1992 13 1 77 81 2-s2.0-0026567346
4. Brown N. S., Bicknell R., Oxidative stress: its effects on the growth, metastatic potential and response to therapy of breast cancer. Oxidative stress: its effects on the growth, metastatic potential and response to therapy of breast cancer. Breast Cancer Research 2001 3 5 323 327 2-s2.0-0034855105 10.1186/bcr315 (Pubitemid 32851163)
5. Kang D.-H., Oxidative stress, DNA damage, and breast cancer. AACN clinical issues 2002 13 4 540 549 2-s2.0-0036832196
6. Brigelius-Flohé R., Kipp A., Glutathione peroxidases in different stages of carcinogenesis. Biochimica et Biophysica Acta 2009 1790 11 1555 1568 2-s2.0-72649092649 10.1016/j.bbagen.2009.03.006
7. Rayman M. P., Selenium in cancer prevention: a review of the evidence and mechanism of action. Proceedings of the Nutrition Society 2005 64 4 527 542 2-s2.0-28244462778 10.1079/PNS2005467 (Pubitemid 41705454)
8. Wang J.-Y., Yang I.-P., Wu D.-C., Huang S.-W., Wu J.-Y., Juo S.-H. H., Functional glutathione peroxidase 3 polymorphisms associated with increased risk of Taiwanese patients with gastric cancer. Clinica Chimica Acta 2010 411 19-20 1432 1436 2-s2.0-77955053926 10.1016/j.cca.2010.05.026
9. Pawlowicz Z., Zachara B. A., Trafikowska U., Maciag A., Marchaluk E., Nowicki A., Blood selenium concentrations and glutathione peroxidase activities in patients with breast cancer and with advanced gastrointestinal cancer. Journal of Trace Elements and Electrolytes in Health and Disease 1991 5 4 275 277 2-s2.0-0026337386
10. Yu Y. P., Yu G., Tseng G., Cieply K., Nelson J., Defrances M., Zarnegar R., Michalopoulos G., Luo J.-H., Glutathione peroxidase 3, deleted or methylated in prostate cancer, suppresses prostate cancer growth and metastasis. Cancer Research 2007 67 17 8043 8050 2-s2.0-34548572037 10.1158/0008-5472.CAN-07-0648 (Pubitemid 47395138)
11. Hasegawa Y., Takano T., Miyauchi A., Matsuzuka F., Yoshida H., Kuma K., Amino N., Decreased expression of glutathione peroxidase mRNA in thyroid anaplastic carcinoma. Cancer Letters 2002 182 1 69 74 2-s2.0-0037043605 10.1016/S0304-3835(02)00069-1 (Pubitemid 34518658)
12. Lee O.-J., Schneider-Stock R., McChesney P. A., Kuester D., Roessner A., Vieth M., Moskaluk C. A., El-Rifai W., Hypermethylation and loss of expression of glutathione peroxidase-3 in Barrett's tumorigenesis. Neoplasia 2005 7 9 854 861 2-s2.0-33644874224 10.1593/neo.05328
13. He Y., Wang Y., Li P., Zhu S., Wang J., Zhang S., Identification of GPX3 epigenetically silenced by CpG methylation in human esophageal squamous cell carcinoma. Digestive Diseases and Sciences 2011 56 3 681 688 2-s2.0-79952444349 10.1007/s10620-010-1369-0
14. Chen B., Rao X., House M. G., Nephew K. P., Cullen K. J., Guo Z., GPx3 promoter hypermethylation is a frequent event in human cancer and is associated with tumorigenesis and chemotherapy response. Cancer Letters 2011 309 1 37 45 2-s2.0-79959838676 10.1016/j.canlet.2011.05.013
15. Lodygin D., Epanchintsev A., Menssen A., Diebold J., Hermeking H., Functional epigenomics identifies genes frequently silenced in prostate cancer. Cancer Research 2005 65 10 4218 4227 2-s2.0-20144383392 10.1158/0008-5472.CAN- 04-4407 (Pubitemid 40775660)
16. Falck E., Karlsson S., Carlsson J., Helenius G., Karlsson M., Klinga-Levan K., Loss of glutathione peroxidase 3 expression is correlated with epigenetic mechanisms in endometrial adenocarcinoma. Cancer Cell International 2010 10, article 46 2-s2.0-78549258157 10.1186/1475-2867-10-46
17. Zhang X., Yang J.-J., Kim Y. S., Kim K.-Y., Ahn W. S., Yang S., An 8-gene signature, including methylated and down-regulated glutathione peroxidase 3, of gastric cancer. International Journal of Oncology 2010 36 2 405 414 2-s2.0-75449099529 10.3892/ijo-00000513
18. Qu Y., Dang S., Hou P., Gene methylation in gastric cancer. Clinica Chimica Acta 2013 424 53 65
19. Kaiser M. F., Johnson D. C., Wu P., Walker B. A., Brioli A., Mirabella F., Wardell C. P., Melchor L., Davies F. E., Morgan G. J., Global methylation analysis identifies prognostically important epigenetically inactivated tumor suppressor genes in multiple myeloma. Blood 2013 122 2 219 226
20. Peng D. F., Hu T. L., Schneider B. G., Chen Z., Xu Z. K., El-Rifai W., Silencing of glutathione peroxidase 3 through DNA hypermethylation is associated with lymph node metastasis in gastric carcinomas. PLoS ONE 2012 7 10 e46214
21. Nouh M. A., Mohamed M. M., El-Shinawi M., Shaalan M. A., Cavallo-Medved D., Khaled H. M., Sloane B. F., Cathepsin b: a potential prognostic marker for inflammatory breast cancer. Journal of Translational Medicine 2011 9, article 1 2-s2.0-78650727555 10.1186/1479-5876-9-1
22. Bonnier P., Charpin C., Lejeune C., Romain S., Tubiana N., Beedassy B., Martin P. M., Serment H., Piana L., Inflammatory carcinomas of the breast: a clinical, pathological, or a clinical and pathological definition? International Journal of Cancer 1995 62 4 382 385 2-s2.0-0029083919 10.1002/ijc.2910620404
23. Gong Y., Pathologic aspects of inflammatory breast cancer: part 2. Biologic insights into its aggressive phenotype. Seminars in Oncology 2008 35 1 33 40 2-s2.0-39549106867 10.1053/j.seminoncol.2007.11.014 (Pubitemid 351282394)
24. Mohamed M. M., Al-Raawi D., Sabet S. F., El-Shinawi M., Inflammatory breast cancer: new factors contribute to disease etiology (Review). Journal of Advanced Research 2013 10.1016/j.jare.2013.06.004
25. Storz P., Reactive oxygen species in tumor progression. Frontiers in Bioscience 2005 10 2 1881 1896 2-s2.0-17244367828 (Pubitemid 40529044)
26. Lo I.-C., Shih J.-M., Jiang M. J., Reactive oxygen species and ERK 1/2 mediate monocyte chemotactic protein-1-stimulated smooth muscle cell migration. Journal of Biomedical Science 2005 12 2 377 388 2-s2.0-21244497185 10.1007/s11373-005-1703-2 (Pubitemid 40897643)
27. Wu W.-S., The signaling mechanism of ROS in tumor progression. Cancer and Metastasis Reviews 2006 25 4 695 705 2-s2.0-33846117134 10.1007/s10555-006- 9037-8 (Pubitemid 46071872)
28. Genestie C., Zafrani B., Asselain B., Fourquet A., Rozan S., Validire P., Vincent-Salomon A., Sastre-Garau X., Comparison of the prognostic value of Scarff-Bloom-Richardson and Nottingham histological grades in a series of 825 cases of breast cancer: major importance of the mitotic count as a component of both grading systems. Anticancer Research 1998 18 1 571 576 2-s2.0-0031948563 (Pubitemid 28174874)
29. Peng D. F., Razvi M., Chen H., Washington K., Roessner A., Schneider-Stock R., El-Rifai W., DNA hypermethylation regulates the expression of members of the Mu-class glutathione S-transferases and glutathione peroxidases in Barrett's adenocarcinoma. Gut 2009 58 1 5 15 2-s2.0-58249084836 10.1136/gut.2007.146290
30. Christians A., Hartmann C., Benner A., Meyer J., von Deimling A., Weller M., Wick W., Weiler M., Prognostic value of three different methods of MGMT promoter methylation analysis in a prospective trial on newly diagnosed glioblastoma. PLoS ONE 2012 7 3 2-s2.0-84858116907 10.1371/journal.pone.0033449 e33449
31. Hu Y. J., Diamond A. M., Role of glutathione peroxidase 1 in breast cancer: loss of heterozygosity and allelic differences in the response to selenium. Cancer Research 2003 63 12 3347 3351 2-s2.0-0038068938 (Pubitemid 36735893)
32. Cejas P., García-Cabezas M. A., Casado E., Belda-Iniesta C., De Castro J., Fresno J. A., Sereno M., Barriuso J., Espinosa E., Zamora P., Feliu J., Redondo A., Hardisson D. A., Renart J., González-Barón M., Phospholipid Hydroperoxide Glutathione Peroxidase (PHGPx) expression is downregulated in poorly differentiated breast invasive ductal carcinoma. Free Radical Research 2007 41 6 681 687 2-s2.0-34249790862 10.1080/10715760701286167 (Pubitemid 46845589)
33. Woolston C. M., Al-Attar A., Storr S. J., Ellis I. O., Morgan D. A. L., Martin S. G., Redox protein expression predicts radiotherapeutic response in early-stage invasive breast cancer patients. International Journal of Radiation Oncology Biology Physics 2011 79 5 1532 1540 2-s2.0-79952633051 10.1016/j.ijrobp.2010.11.002
34. Ambrosone C. B., Oxidants and antioxidants in breast cancer. Antioxidants and Redox Signaling 2000 2 4 903 917 2-s2.0-0034531005 (Pubitemid 32062336)
35. Perwez Hussain S., Hollstein M. H., Harris C. C., p53 tumor suppressor gene: at the crossroads of molecular carcinogenesis, molecular epidemiology, and human risk assessment. Annals of the New York Academy of Sciences 2000 919 79 85 2-s2.0-0033695273
36. Robertson F. M., Bondy M., Yang W., Yamauchi H., Wiggins S., Kamrudin S., Krishnamurthy S., Le-Petross H., Bidaut L., Player A. N., Barsky S. H., Woodward W. A., Buchholz T., Lucci A., Ueno N., Cristofanilli M., Inflammatory breast cancer the disease, the biology, the treatment. CA Cancer Journal for Clinicians 2010 60 6 351 375 2-s2.0-78649359184 10.3322/caac.20082
37. Mohamed M. M., El-Ghonaimy E. A., Nouh M. A., Schneider R. J., Sloane B. F., El-Shinawi M., Cytokines secreted by macrophages isolated from tumor microenvironment of inflammatory breast cancer patients possess chemotactic properties. The International Journal of Biochemistry & Cell Biology 2014 46 138 147
38. Barrett C. W., Ning W., Chen X., Smith J. J., Washington M. K., Hill K. E., Coburn L. A., Peek R. M., Chaturvedi R., Wilson K. T., Burk R. F., Williams C. S., Tumor suppressor function of the plasma glutathione peroxidase gpx3 in colitis-associated carcinoma. Cancer Research 2013 73 3 1245 1255