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Volumn 123, Issue 12, 2014, Pages 1917-1926

Molecular mechanisms underlying synergistic adhesion of sickle red blood cells by hypoxia and low nitric oxide bioavailability

Author keywords

[No Author keywords available]

Indexed keywords

MITOGEN ACTIVATED PROTEIN KINASE P38; NITRIC OXIDE; PADGEM PROTEIN;

EID: 84897496884     PISSN: 00064971     EISSN: 15280020     Source Type: Journal    
DOI: 10.1182/blood-2013-06-510180     Document Type: Article
Times cited : (28)

References (49)
  • 1
    • 0018885938 scopus 로고
    • Erythrocyte adherence to endothelium in sickle-cell anemia. A possible determinant of disease severity
    • Hebbel RP, Boogaerts MA, Eaton JW, Steinberg MH. Erythrocyte adherence to endothelium in sickle-cell anemia. A possible determinant of disease severity. N Engl J Med. 1980;302(18):992-995. (Pubitemid 10125408)
    • (1980) New England Journal of Medicine , vol.302 , Issue.18 , pp. 992-995
    • Hebbel, R.P.1    Boogaerts, M.A.B.2    Eaton, J.W.3    Steinberg, M.H.4
  • 2
    • 0021815445 scopus 로고
    • Kinetics of sickle hemoglobin polymerization. I. Studies using temperature-jump and laser photolysis techniques
    • DOI 10.1016/0022-2836(85)90174-3
    • Ferrone FA, Hofrichter J, Eaton WA. Kinetics of sickle hemoglobin polymerization. I. Studies using temperature-jump and laser photolysis techniques. J Mol Biol. 1985;183(4):591-610. (Pubitemid 15036850)
    • (1985) Journal of Molecular Biology , vol.183 , Issue.4 , pp. 591-610
    • Ferrone, F.A.1    Hofrichter, J.2    Eaton, W.A.3
  • 3
    • 43249105788 scopus 로고    scopus 로고
    • Efficacy and safety of the Gardos channel blocker, senicapoc (ICA-17043), in patients with sickle cell anemia
    • ICA-17043-05 Investigators
    • Ataga KI, Smith WR, De Castro LM, et al. ICA-17043-05 Investigators. Efficacy and safety of the Gardos channel blocker, senicapoc (ICA-17043), in patients with sickle cell anemia. Blood. 2008;111(8):3991-3997.
    • (2008) Blood , vol.111 , Issue.8 , pp. 3991-3997
    • Ataga, K.I.1    Smith, W.R.2    De Castro, L.M.3
  • 4
    • 0036177721 scopus 로고    scopus 로고
    • Sickle cell vaso-occlusion: Multistep and multicellular paradigm
    • DOI 10.1097/00062752-200203000-00003
    • Frenette PS. Sickle cell vaso-occlusion: multistep and multicellular paradigm. Curr Opin Hematol. 2002;9(2):101-106. (Pubitemid 34171484)
    • (2002) Current Opinion in Hematology , vol.9 , Issue.2 , pp. 101-106
    • Frenette, P.S.1
  • 5
    • 0034321784 scopus 로고    scopus 로고
    • Patterns of arginine and nitric oxide in patients with sickle cell disease with vaso-occlusive crisis and acute chest syndrome
    • Morris CR, Kuypers FA, Larkin S, Vichinsky EP, Styles LA. Patterns of arginine and nitric oxide in patients with sickle cell disease with vaso-occlusive crisis and acute chest syndrome. J Pediatr Hematol Oncol. 2000;22(6):515-520.
    • (2000) J Pediatr Hematol Oncol , vol.22 , Issue.6 , pp. 515-520
    • Morris, C.R.1    Kuypers, F.A.2    Larkin, S.3    Vichinsky, E.P.4    Styles, L.A.5
  • 7
    • 65349087881 scopus 로고    scopus 로고
    • Endogenous nitric oxide synthase inhibitors in sickle cell disease: Abnormal levels and correlations with pulmonary hypertension, desaturation, haemolysis, organ dysfunction and death
    • Kato GJ, Wang Z, Machado RF, Blackwelder WC, Taylor JG VI, Hazen SL. Endogenous nitric oxide synthase inhibitors in sickle cell disease: abnormal levels and correlations with pulmonary hypertension, desaturation, haemolysis, organ dysfunction and death. Br J Haematol. 2009;145(4):506-513.
    • (2009) Br J Haematol , vol.145 , Issue.4 , pp. 506-513
    • Kato, G.J.1    Wang, Z.2    Machado, R.F.3    Blackwelder, W.C.4    Taylor VI, J.G.5    Hazen, S.L.6
  • 9
    • 0028825749 scopus 로고
    • Regulation of bovine endothelial constitutive nitric oxide synthase by oxygen
    • Liao JK, Zulueta JJ, Yu FS, Peng HB, Cote CG, Hassoun PM. Regulation of bovine endothelial constitutive nitric oxide synthase by oxygen. J Clin Invest. 1995;96(6):2661-2666.
    • (1995) J Clin Invest , vol.96 , Issue.6 , pp. 2661-2666
    • Liao, J.K.1    Zulueta, J.J.2    Yu, F.S.3    Peng, H.B.4    Cote, C.G.5    Hassoun, P.M.6
  • 11
    • 0034989750 scopus 로고    scopus 로고
    • Inhaled nitric oxide improves survival rates during hypoxia in a sickle cell (SAD) mouse model
    • Martinez-Ruiz R, Montero-Huerta P, Hromi J, Head CA. Inhaled nitric oxide improves survival rates during hypoxia in a sickle cell (SAD) mouse model. Anesthesiology. 2001;94(6):1113-1118. (Pubitemid 32506141)
    • (2001) Anesthesiology , vol.94 , Issue.6 , pp. 1113-1118
    • Martinez-Ruiz, R.1    Montero-Huerta, P.2    Hromi, J.3    Head, C.A.4
  • 14
    • 79955890832 scopus 로고    scopus 로고
    • Nitric oxide reduces sickle hemoglobin polymerization: Potential role of nitric oxide-induced charge alteration in depolymerization
    • Ikuta T, Thatte HS, Tang JX, et al. Nitric oxide reduces sickle hemoglobin polymerization: potential role of nitric oxide-induced charge alteration in depolymerization. Arch Biochem Biophys. 2011;510(1):53-61.
    • (2011) Arch Biochem Biophys , vol.510 , Issue.1 , pp. 53-61
    • Ikuta, T.1    Thatte, H.S.2    Tang, J.X.3
  • 15
    • 0034102968 scopus 로고    scopus 로고
    • Nitric oxide attenuates normal and sickle red blood cell adherence to pulmonary endothelium
    • DOI 10.1002/(SICI)1096-8652(200004)63:4<200::AID
    • Space SL, Lane PA, Pickett CK, Weil JV. Nitric oxide attenuates normal and sickle red blood cell adherence to pulmonary endothelium. Am J Hematol. 2000;63(4):200-204. (Pubitemid 30165407)
    • (2000) American Journal of Hematology , vol.63 , Issue.4 , pp. 200-204
    • Space, S.L.1    Lane, P.A.2    Pickett, C.K.3    Weil, J.V.4
  • 16
    • 0030725279 scopus 로고    scopus 로고
    • Knockout-transgenic mouse model of sickle cell disease
    • DOI 10.1126/science.278.5339.873
    • Ryan TM, Ciavatta DJ, Townes TM. Knockout-transgenic mouse model of sickle cell disease. Science. 1997;278(5339):873-876. (Pubitemid 27467926)
    • (1997) Science , vol.278 , Issue.5339 , pp. 873-876
    • Ryan, T.M.1    Ciavatta, D.J.2    Townes, T.M.3
  • 18
    • 78751507531 scopus 로고    scopus 로고
    • Inhibition of cell adhesion by anti-P-selectin aptamer: A new potential therapeutic agent for sickle cell disease
    • Gutsaeva DR, Parkerson JB, Yerigenahally SD, et al. Inhibition of cell adhesion by anti-P-selectin aptamer: a new potential therapeutic agent for sickle cell disease. Blood. 2011;117(2):727-735.
    • (2011) Blood , vol.117 , Issue.2 , pp. 727-735
    • Gutsaeva, D.R.1    Parkerson, J.B.2    Yerigenahally, S.D.3
  • 19
    • 1542267418 scopus 로고    scopus 로고
    • Negative regulation of γ-globin gene expression by cyclic AMP-dependent pathway in erythroid cells
    • DOI 10.1016/j.exphem.2003.12.006, PII S0301472X03004223
    • Inoue A, Kuroyanagi Y, Terui K, Moi P, Ikuta T. Negative regulation of γ-globin gene expression by cyclic AMP-dependent pathway in erythroid cells. Exp Hematol. 2004;32(3):244-253. (Pubitemid 38328529)
    • (2004) Experimental Hematology , vol.32 , Issue.3 , pp. 244-253
    • Inoue, A.1    Kuroyanagi, Y.2    Terui, K.3    Moi, P.4    Ikuta, T.5
  • 21
    • 0034658663 scopus 로고    scopus 로고
    • Perfusion with sickle erythrocytes up-regulates ICAM-1 and VCAM-1 gene expression in cultured human endothelial cells
    • Shiu YT, Udden MM, McIntire LV. Perfusion with sickle erythrocytes up-regulates ICAM-1 and VCAM-1 gene expression in cultured human endothelial cells. Blood. 2000;95(10):3232-3241. (Pubitemid 30321179)
    • (2000) Blood , vol.95 , Issue.10 , pp. 3232-3241
    • Shiu, Y.-T.1    Udden, M.M.2    McIntire, L.V.3
  • 22
    • 45949101608 scopus 로고    scopus 로고
    • The vessel wall and its interactions
    • Wagner DD, Frenette PS. The vessel wall and its interactions. Blood. 2008;111(11):5271-5281.
    • (2008) Blood , vol.111 , Issue.11 , pp. 5271-5281
    • Wagner, D.D.1    Frenette, P.S.2
  • 23
    • 0022221113 scopus 로고
    • A platelet alpha-granule membrane protein (GMP-140) is expressed on the plasma membrane after activation
    • DOI 10.1083/jcb.101.3.880
    • Stenberg PE, McEver RP, Shuman MA, Jacques YV, Bainton DF. A platelet alpha-granule membrane protein (GMP-140) is expressed on the plasma membrane after activation. J Cell Biol. 1985;101(3):880-886. (Pubitemid 16256841)
    • (1985) Journal of Cell Biology , vol.101 , Issue.3 , pp. 880-886
    • Stenberg, P.E.1    McEver, R.P.2    Shuman, M.A.3
  • 24
    • 0033551609 scopus 로고    scopus 로고
    • Selective activation of p38α and p38γ by hypoxia. Role in regulation of cyclin D1 by hypoxia in PC12 cells
    • Conrad PW, Rust RT, Han J, Millhorn DE, Beitner-Johnson D. Selective activation of p38α and p38γ by hypoxia. Role in regulation of cyclin D1 by hypoxia in PC12 cells. J Biol Chem. 1999; 274(33):23570-23576.
    • (1999) J Biol Chem , vol.274 , Issue.33 , pp. 23570-23576
    • Conrad, P.W.1    Rust, R.T.2    Han, J.3    Millhorn, D.E.4    Beitner-Johnson, D.5
  • 26
    • 0033198521 scopus 로고    scopus 로고
    • Sickle cell acute chest syndrome: Pathogenesis and rationale for treatment
    • Stuart MJ, Setty BNY. Sickle cell acute chest syndrome: pathogenesis and rationale for treatment. Blood. 1999;94(5):1555-1560. (Pubitemid 29411305)
    • (1999) Blood , vol.94 , Issue.5 , pp. 1555-1560
    • Stuart, M.J.1    Setty, B.N.Y.2
  • 27
    • 0032738619 scopus 로고    scopus 로고
    • Nitric oxide successfully used to treat acute chest syndrome of sickle cell disease in a young adolescent
    • Sullivan KJ, Goodwin SR, Evangelist J, Moore RD, Mehta P. Nitric oxide successfully used to treat acute chest syndrome of sickle cell disease in a young adolescent. Crit Care Med. 1999;27(11):2563-2568.
    • (1999) Crit Care Med , vol.27 , Issue.11 , pp. 2563-2568
    • Sullivan, K.J.1    Goodwin, S.R.2    Evangelist, J.3    Moore, R.D.4    Mehta, P.5
  • 28
    • 0037420269 scopus 로고    scopus 로고
    • Preliminary Assessment of Inhaled Nitric Oxide for Acute Vaso-occlusive Crisis in Pediatric Patients with Sickle Cell Disease
    • DOI 10.1001/jama.289.9.1136
    • Weiner DL, Hibberd PL, Betit P, Cooper AB, Botelho CA, Brugnara C. Preliminary assessment of inhaled nitric oxide for acute vaso-occlusive crisis in pediatric patients with sickle cell disease [published correction appears in JAMA. 2004;292(8):925]. JAMA. 2003;289(9):1136-1142. (Pubitemid 37430328)
    • (2003) Journal of the American Medical Association , vol.289 , Issue.9 , pp. 1136-1142
    • Weiner, D.L.1    Hibberd, P.L.2    Betit, P.3    Cooper, A.B.4    Botelho, C.A.5    Brugnara, C.6
  • 29
    • 77957656805 scopus 로고    scopus 로고
    • Beneficial effects of nitric oxide breathing in adult patients with sickle cell crisis
    • Head CA, Swerdlow P, McDade WA, et al. Beneficial effects of nitric oxide breathing in adult patients with sickle cell crisis. Am J Hematol. 2010;85(10):800-802.
    • (2010) Am J Hematol , vol.85 , Issue.10 , pp. 800-802
    • Head, C.A.1    Swerdlow, P.2    McDade, W.A.3
  • 30
    • 0035885941 scopus 로고    scopus 로고
    • P-selectin mediates the adhesion of sickle erythrocytes to the endothelium
    • Matsui NM, Borsig L, Rosen SD, Yaghmai M, Varki A, Embury SH. P-selectin mediates the adhesion of sickle erythrocytes to the endothelium. Blood. 2001;98(6):1955-1962.
    • (2001) Blood , vol.98 , Issue.6 , pp. 1955-1962
    • Matsui, N.M.1    Borsig, L.2    Rosen, S.D.3    Yaghmai, M.4    Varki, A.5    Embury, S.H.6
  • 33
    • 27144476793 scopus 로고    scopus 로고
    • Activated platelets induce Weibel-Palade-body secretion and leukocyte rolling in vivo: Role of P-selectin
    • DOI 10.1182/blood-2005-04-1530
    • Dole VS, Bergmeier W, Mitchell HA, Eichenberger SC, Wagner DD. Activated platelets induce Weibel-Palade-body secretion and leukocyte rolling in vivo: role of P-selectin. Blood. 2005;106(7):2334-2339. (Pubitemid 41510804)
    • (2005) Blood , vol.106 , Issue.7 , pp. 2334-2339
    • Dole, V.S.1    Bergmeier, W.2    Mitchell, H.A.3    Eichenberger, S.C.4    Wagner, D.D.5
  • 34
    • 79952233719 scopus 로고    scopus 로고
    • Nitric oxide for inhalation in the acute treatment of sickle cell pain crisis: A randomized controlled trial
    • DeNOVO Investigators
    • Gladwin MT, Kato GJ, Weiner D, et al; DeNOVO Investigators. Nitric oxide for inhalation in the acute treatment of sickle cell pain crisis: a randomized controlled trial. JAMA. 2011;305(9):893-902.
    • (2011) JAMA , vol.305 , Issue.9 , pp. 893-902
    • Gladwin, M.T.1    Kato, G.J.2    Weiner, D.3
  • 35
    • 0029025475 scopus 로고
    • Effect of hydroxyurea on the frequency of painful crises in sickle cell anemia
    • Investigators of the Multicenter Study of Hydroxyurea in Sickle Cell Anemia
    • Charache S, Terrin ML, Moore RD, et al Investigators of the Multicenter Study of Hydroxyurea in Sickle Cell Anemia. Effect of hydroxyurea on the frequency of painful crises in sickle cell anemia. N Engl J Med. 1995;332(20):1317-1322.
    • (1995) N Engl J Med , vol.332 , Issue.20 , pp. 1317-1322
    • Charache, S.1    Terrin, M.L.2    Moore, R.D.3
  • 37
    • 49349104104 scopus 로고    scopus 로고
    • A cell stress signaling model of fetal hemoglobin induction: What doesn't kill red blood cells may make them stronger
    • Mabaera R, West RJ, Conine SJ, et al. A cell stress signaling model of fetal hemoglobin induction: what doesn't kill red blood cells may make them stronger. Exp Hematol. 2008;36(9):1057-1072.
    • (2008) Exp Hematol , vol.36 , Issue.9 , pp. 1057-1072
    • Mabaera, R.1    West, R.J.2    Conine, S.J.3
  • 39
    • 35548943647 scopus 로고    scopus 로고
    • Thalidomide induces gamma-globin gene expression through increased reactive oxygen species-mediated p38 MAPK signaling and histone H4 acetylation in adult erythropoiesis
    • DOI 10.1182/blood-2007-01-065201
    • Aerbajinai W, Zhu J, Gao Z, Chin K, Rodgers GP. Thalidomide induces gamma-globin gene expression through increased reactive oxygen species-mediated p38 MAPK signaling and histone H4 acetylation in adult erythropoiesis. Blood. 2007;110(8):2864-2871. (Pubitemid 350006939)
    • (2007) Blood , vol.110 , Issue.8 , pp. 2864-2871
    • Aerbajinai, W.1    Zhu, J.2    Gao, Z.3    Chin, K.4    Rodgers, G.P.5
  • 40
    • 84863421480 scopus 로고    scopus 로고
    • Erythrocyte plasma membrane-bound ERK1/2 activation promotes ICAM-4-mediated sickle red cell adhesion to endothelium
    • Zennadi R, Whalen EJ, Soderblom EJ, et al. Erythrocyte plasma membrane-bound ERK1/2 activation promotes ICAM-4-mediated sickle red cell adhesion to endothelium. Blood. 2012;119(5):1217-1227.
    • (2012) Blood , vol.119 , Issue.5 , pp. 1217-1227
    • Zennadi, R.1    Whalen, E.J.2    Soderblom, E.J.3
  • 41
    • 33646137140 scopus 로고    scopus 로고
    • cAMP differentially regulates g-globin gene expression in erythroleukemic cells and primary erythroblasts through c-Myb expression
    • Kuroyanagi Y, Kaneko Y, Muta K, et al. cAMP differentially regulates g-globin gene expression in erythroleukemic cells and primary erythroblasts through c-Myb expression. Biochem Biophys Res Commun. 2006;344(3):1038-1047.
    • (2006) Biochem Biophys Res Commun , vol.344 , Issue.3 , pp. 1038-1047
    • Kuroyanagi, Y.1    Kaneko, Y.2    Muta, K.3
  • 42
    • 0033789442 scopus 로고    scopus 로고
    • Acetylcholine prevents intercellular adhesion molecule 1 (CD54)-induced focal adhesion complex assembly in endothelial cells via a nitric oxide-cGMP-dependent pathway
    • Clancy RM, Abramson SB. Acetylcholine prevents intercellular adhesion molecule 1 (CD54)-induced focal adhesion complex assembly in endothelial cells via a nitric oxide-cGMP-dependent pathway. Arthritis Rheum. 2000;43(10):2260- 2264.
    • (2000) Arthritis Rheum , vol.43 , Issue.10 , pp. 2260-2264
    • Clancy, R.M.1    Abramson, S.B.2
  • 43
    • 77956582086 scopus 로고    scopus 로고
    • GMI-1070, a novel pan-selectin antagonist, reverses acute vascular occlusions in sickle cell mice
    • Chang J, Patton JT, Sarkar A, Ernst B, Magnani JL, Frenette PS. GMI-1070, a novel pan-selectin antagonist, reverses acute vascular occlusions in sickle cell mice. Blood. 2010;116(10):1779-1786.
    • (2010) Blood , vol.116 , Issue.10 , pp. 1779-1786
    • Chang, J.1    Patton, J.T.2    Sarkar, A.3    Ernst, B.4    Magnani, J.L.5    Frenette, P.S.6
  • 44
    • 0029832409 scopus 로고    scopus 로고
    • Tumor necrosis factor-induced E-selectin expression on vascular endothelial cells
    • Gedeit RG. Tumor necrosis factor-induced E-selectin expression on vascular endothelial cells. Crit Care Med. 1996;24(9):1543-1546. (Pubitemid 26313758)
    • (1996) Critical Care Medicine , vol.24 , Issue.9 , pp. 1543-1546
    • Gedeit, R.G.1
  • 45
    • 0030892382 scopus 로고    scopus 로고
    • Interleukin-4 suppression of tumor necrosis factor alpha-stimulated E- selectin gene transcription is mediated by STAT6 antagonism of NF-kappaB
    • DOI 10.1074/jbc.272.15.10212
    • Bennett BL, Cruz R, Lacson RG, Manning AM. Interleukin-4 suppression of tumor necrosis factor alpha-stimulated E-selectin gene transcription is mediated by STAT6 antagonism of NF-kappaB. J Biol Chem. 1997;272(15):10212-10219. (Pubitemid 27171700)
    • (1997) Journal of Biological Chemistry , vol.272 , Issue.15 , pp. 10212-10219
    • Bennett, B.L.1    Cruz, R.2    Lacson, R.G.3    Manning, A.M.4
  • 46
    • 0031439514 scopus 로고    scopus 로고
    • Adhesive interactions of sickle erythrocytes with endothelium
    • Hebbel RP. Adhesive interactions of sickle erythrocytes with endothelium. J Clin Invest. 1997;100(11, suppl):S83-S86. (Pubitemid 28009552)
    • (1997) Journal of Clinical Investigation , vol.100 , Issue.11 SUPPL.
    • Hebbel, R.P.1
  • 47
    • 50049113011 scopus 로고    scopus 로고
    • Sodium nitrite promotes regional blood flow in patients with sickle cell disease: A phase I/II study
    • Mack AK, McGowan Ii VR, Tremonti CK, et al. Sodium nitrite promotes regional blood flow in patients with sickle cell disease: a phase I/II study. Br J Haematol. 2008;142(6):971-978.
    • (2008) Br J Haematol , vol.142 , Issue.6 , pp. 971-978
    • Mack, A.K.1    McGowan Ii, V.R.2    Tremonti, C.K.3
  • 48
    • 78049238308 scopus 로고    scopus 로고
    • Dietary inorganic nitrate reverses features of metabolic syndrome in endothelial nitric oxide synthasedeficient mice
    • Carlström M, Larsen FJ, Nyström T, et al. Dietary inorganic nitrate reverses features of metabolic syndrome in endothelial nitric oxide synthasedeficient mice. Proc Natl Acad Sci USA. 2010;107(41):17716-17720.
    • (2010) Proc Natl Acad Sci USA , vol.107 , Issue.41 , pp. 17716-17720
    • Carlström, M.1    Larsen, F.J.2    Nyström, T.3
  • 49
    • 0021270306 scopus 로고
    • Effects of oxygen inhalation on endogenous erythropoietin kinetics, erythropoiesis, and properties of blood cells in sickle-cell anemia
    • Embury SH, Garcia JF, Mohandas N, Pennathur-Das R, Clark MR. Effects of oxygen inhalation on endogenous erythropoietin kinetics, erythropoiesis, and properties of blood cells in sickle-cell anemia. N Engl J Med. 1984;311(5):291-295. (Pubitemid 14091207)
    • (1984) New England Journal of Medicine , vol.311 , Issue.5 , pp. 291-295
    • Embury, S.H.1    Garcia, J.F.2    Mohandas, N.3


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