Evidence informing the intersection of HIV, aging and health: A scoping review

AIDS and Behavior

Volumn 18, Issue 4, 2014, Pages 661-675

  Chambers, Lori A ^a,b   Wilson, Michael G ^a,b,c,d   Rueda, Sergio ^a,e   Gogolishvili, David ^a   Shi, Maggie Qiyun ^a   Rourke, Sean B ^a,e,f   Team, The Positive Aging Review ^a  

^a ONTARIO HIV TREATMENT NETWORK   (Canada)

^b MCMASTER UNIVERSITY   (Canada)

^c MCMASTER UNIVERSITY   (Canada)

^d MCMASTER UNIVERSITY   (Canada)

^e UNIVERSITY OF TORONTO   (Canada)

^f ST MICHAEL'S HOSPITAL   (Canada)

Author keywords

Aging; Health; Health care utilization; Sexual health; Social participation

Indexed keywords

AGED; AGING; ATTITUDE TO HEALTH; DISEASE COURSE; FEMALE; HIGH RISK BEHAVIOR; HIV INFECTIONS; HUMAN; MALE; MANAGEMENT; MEDICATION COMPLIANCE; MIDDLE AGED; PATIENT ATTITUDE; PSYCHOLOGY; SEXUAL BEHAVIOR; SOCIAL STIGMA; SOCIAL SUPPORT; STATISTICS AND NUMERICAL DATA;

AGED; AGING; DISEASE PROGRESSION; FEMALE; HEALTH KNOWLEDGE, ATTITUDES, PRACTICE; HIV INFECTIONS; HUMANS; MALE; MEDICATION ADHERENCE; MIDDLE AGED; PATIENT ACCEPTANCE OF HEALTH CARE; POLICY MAKING; RISK-TAKING; SEXUAL BEHAVIOR; SOCIAL STIGMA; SOCIAL SUPPORT;

EID: 84897471562     PISSN: 10907165     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10461-013-0627-5     Document Type: Review

References (102)

1. Karpiak SE, Shippy RA, Cantor M. Research on older adults with HIV. New York: AIDS Community Research Initiative of America; 2006.
2. World Health Organization. Impact of HIV/AIDS on older people in Africa: WHO. http://www.who.int/ageing/projects/hiv/en/index.html (2012). Accessed 24 May 2012.
3. Centers for Disease Control and Prevention. Diagnoses of HIV infection among adults aged 50 years and older in the United States and dependent areas, 2007-2010. HIV Surveillance Supplemental Report. http://www.cdc.gov/hiv/library/ reports/surveillance/index.html (2013). Accessed 15 May 2013.
4. Effros RB, Fletcher CV, Gebo K, Halter JB, Hazzard WR, Horne FM, et al. Workshop on HIV infection and aging: what is known and future research directions. Clin Infect Dis. 2008;47(4):542-53.
5. Public Health Agency of Canada. HIV/AIDS Epi Updates N. HIV/AIDS Epi Updates, November 2007. Ottawa: Surveillance and Risk Assessment Division, Centre for Infectious Disease Prevention and Control, Public Health Agency of Canada; 2007.
6. AVERTing HIV and AIDS. United Kingdom statistics by race, age and gender: AVERT. http://www.avert.org/uk-race-age-gender.htm (2010). Accessed 25 May 2012.
7. Terrence Higgins Trust (THT): Information resources: HIV and AIDS: Personal experiences of HIV: 50 plus London, UK: Author. http://www.tht.org.uk/ informationresources/hivandaids/personal-experiences-of-hiv/50plus/ (2012). Accessed 25 May 2012.
8. Health Protection Agency. United Kingdom: New HIV Diagnoses data to end December 2011. Tables No.2:2011 (2012). http://www.hpa.org.uk/webc/HPAwebFile/ HPAweb-C/1237970242135. Accessed 8 Apr 2012.
9. Public Health Agency of Canada. HIV and AIDS in Canada. Surveillance Report to December 31, 2009. Ottawa: Surveillance and Risk Assessment Division, Centre for Communicable Diseases and Infection Control, Public Health Agency of Canada; 2010.
10. Health Protection Agency (HPK). HIV in the United Kingdom: 2008 Report. London: HPK; 2008.
11. Mutevedzi PC, Newell ML. A missing piece in the puzzle: HIV in mature adults in sub-Saharan Africa. Future Virol. 2011;6(6):755-67.
12. Pearline RV, Tucker JD, Yuan LF, Bu J, Yin YP, Chen XS, et al. Sexually transmitted infections among individuals over fifty years of age in China. AIDS Patient Care STDs. 2010;24(6):345.
13. Negin J, Cumming RG. HIV infection in older adults in sub-Saharan Africa: extrapolating prevalence from existing data. Bull WHO. 2010;88(11):847-53.
14. Brasileiro M, Freitas MIF. Social representations about AIDS in people over 50, infected by HIV. Revista Latino-Americana de Enfermagem (RLAE). 2006;14(5):789-95.
15. Canadian Working Group on HIV and Rehabilitation. HIV and aging background paper for the partners in Aging National Forum. 6th Canadian HIV/AIDS Skills Building Symposium, Montreal, QC2010, 22 Feb 2010.
16. Önen NF, Overton ET. HIV and aging: two converging epidemics. Mo Med. 2009;106(4):269-73.
17. High KP, Brennan-Ing M, Clifford DB, Cohen MH, Currier J, Deeks SG, et al. HIV and aging: state of knowledge and areas of critical need for research. A report to the NIH Office of AIDS Research by the HIV and aging working group. J Acquir Immune Defic Syndr. 2012;60(Suppl 1):S1-18.
18. Gebo KA. HIV and aging: implications for patient management. Drugs Aging. 2006;23(11):897-913.
19. Shah S, Mildvan D. HIV and aging. Curr Infect Dis Rep. 2006;8(3):241-7.
20. Gonzalez R, Cherner M. Co-factors in HIV neurobehavioural disturbances: substance abuse, hepatitis C and aging. Int Rev Psychiatry. 2008;20(1):49-60.
21. Capeau J. From lipodystrophy and insulin resistance to metabolic syndrome: HIV infection, treatment and aging. Curr Opin HIV AIDS. 2007;2(4):247-52.
22. Casau NC. Perspective on HIV infection and aging: emerging research on the horizon. Clin Infect Dis. 2005;41(6):855-63.
23. Smith RD, Delpech VC, Brown AE, Rice BD. HIV transmission and high rates of late diagnoses among adults aged 50 years and over. AIDS. 2010;24(13):2109-15.
24. Mutevedzi PC, Lessells RJ, Rodger AJ, Newell M-L. Association of age with mortality and virological and immunological response to antiretroviral therapy in rural South African adults. PLoS One. 2011;6(7):e21795.
25. Althoff K, Justice A, Gange S, Deeks S, Saag M, Silverberg M, et al. Virologic and immunologic response to HAART, by age and regimen class. AIDS. 2010;24(16):2469-79.
26. Grabar S, Kousignian I, Sobel A, Le Bras P, Gasnault J, Enel P, et al. Immunologic and clinical responses to highly active antiretroviral therapy over 50 years of age. Results from the French Hospital Database on HIV. AIDS. 2004;18(15):2029-38.
27. Peate I. Human immunodeficiency virus and the older person. Br J Nurs. 2007;16(10):606-10.
28. Vance DE, Struzick TC. Addressing risk factors of cognitive impairment in adults aging with HIV: a social work model. J Gerontol Soc Work. 2007;49(4):51-77.
29. Valcour V, Shikuma C, Shiramizu B, Watters M, Poff P, Selnes O, et al. Higher frequency of dementia in older HIV-1 individuals: the Hawaii aging with HIV-1 cohort. Neurology. 2004;63(5):822-7.
30. McMurtray A, Nakamoto B, Shikuma C, Valcour V. Cortical atrophy and white matter hyperintensities in HIV: the Hawaii Aging with HIV Cohort Study. J Stroke Cerebrovasc Dis. 2008;17(4):212-7.
31. Valcour V, Shikuma C, Shiramizu B, Watters M, Poff P, Selnes OA, et al. Age, apolipoprotein E4, and the risk of HIV dementia: the Hawaii aging with HIV cohort. J Neuroimmunol. 2004;157(1-2 Spec Iss):197-202.
32. Vance DE, Moneyham L, Farr KF. Suicidal ideation in adults aging with HIV: neurological and cognitive considerations. J Psychosoc Nurs Ment Health Serv. 2008;46(11):33-8.
33. Heckman TG, Kochman A, Sikkema KJ. Depressive symptoms in older adults living with HIV disease: application of the chronic illness quality of life model. J Ment Health Aging. 2002;8(4):267-79.
34. Shippy RA, Karpiak SE. Aging HIV/AIDS population: fragile social networks. Aging Ment Health. 2005;9(3):246-54.
35. Emlet CA. An examination of the social networks and social isolation in older and younger adults living with HIV/AIDS. Health Soc Work. 2006;31(4):299-308.
36. Vance DE, Moneyham L, Fordham P, Struzick TC. A model of suicidal ideation in adults aging with HIV. J Assoc Nurses AIDS Care. 2008;5:375-84.
37. Shippy RA, Karpiak SE. Perceptions of support among older adults with HIV. Res Aging. 2005;27(3):290-306.
38. Vance DE, Woodley RA. Strengths and distress in adults who are aging with HIV: a pilot study. Psychol Rep. 2005;96(2):383-6.
39. Schrimshaw EW, Siegel K. Perceived barriers to social support from family and friends among older adults with HIV/AIDS. J Health Psychol. 2003;8(6):738-52.
40. Schmid GP, Williams BG, Garcia-Calleja JM, Miller C, Segar E, Southworth M, et al. The unexplored story of HIV and ageing. Bull WHO. 2009;87(3):162. doi: 10.2471/BLT.09.064030.
41. Schick V, Herbenick D, Reece M, Sanders SA, Dodge B, Middlestadt SE, et al. Sexual behaviors, condom use, and sexual health of Americans over 50: implications for sexual health promotion for older adults. J Sex Med. 2010;7:315-29.
42. Lindau ST, Schumm LP, Laumann EO, Levinson W, O'Muircheartaigh CA, Waite LJ. A study of sexuality and health among older adults in the United States. New Engl J Med. 2007;357(8):762-74.
43. Lovejoy TI, Heckman TG, Sikkema KJ, Hansen NB, Kochman A, Suhr JA, et al. Patterns and correlates of sexual activity and condom use behavior in persons 50-plus years of age living with HIV/AIDS. AIDS Behav. 2008;6:943-56.
44. Cooperman NA, Arnsten JH, Klein RS. Current sexual activity and risky sexual behavior in older men with or at risk for HIV infection. AIDS Educ Prev. 2007;19(4):321-33.
45. Crum NF, Furtek KJ, Olson PE, Amling CL, Wallace MR. A review of hypogonadism and erectile dysfunction among HIV-infected men during the pre- and post-HAART eras: diagnosis, pathogenesis, and management. AIDS Patient Care STDs. 2005;19(10):655-71.
46. Centers for Disease Control and Prevention. CDC HIV/AIDS Facts: HIV/AIDS among persons aged 50 and older [Fact Sheet]. Atlanta: US: DHHS, CDC, 2008.
47. Arksey H, O'Malley L. Scoping studies: towards a methodological framework. Int J Soc Res Methodol. 2005;8(1):19-32.
48. Mays N, Roberts E, Popay J. Synthesising research evidence. In: Fulop N, Allen P, Clarke A, Black N, editors. Studying the organisation and delivery of health services: research methods. London: Routlidge; 2001. p. 188-220.
49. Straus SE, Holroyd-Leduc J. Knowledge-to-action cycle. Evid Based Med. 2008;13(4):98-100.
50. Shea B, Grimshaw J, Wells G, Boers M, Andersson N, Hamel C, et al. Development of AMSTAR: a measurement tool to assess the methodological quality of systematic reviews. BMC Med Res Methodol. 2007;7(1):10-6.
51. Oxman AD, Fretheim A, Schünemann HJ. Improving the use of research evidence in guideline development: introduction. Health Res Policy Syst. 2006;4(1):12.
52. Canadian Coordinating Office for Health Technology Assessment. Evaluation tools for COMPUS. http://www.cadth.ca/media/compus/pdf/COMPUS-Evaluation- Methodology-final-e.pdf: 2005.
53. Kearney F, Moore AR, Donegan CF, Lambert J. The ageing of HIV: implications for geriatric medicine. Age Ageing. 2010;39(5):536-41.
54. Sankar A, Nevedal A, Neufeld S, Berry R, Luborsky M. What do we know about older adults and HIV? A review of social and behavioral literature. AIDS Care. 2011;23(10):1187-207.
55. Cochrane Handbook for Systematic Reviews of Interventions: The Cochrane Collaboration; 2011. Available from: www.cochrane-handbook.org. Accessed 15 May 2013.
56. Brennan M, Strauss SM, Karpiak SE. Religious congregations and the growing needs of older adults with HIV. J Relig Spiritual Aging. 2010;22(4):307-28.
57. Poindexter CC, Shippy RA. HIV diagnosis disclosure: stigma management and stigma Resistance. J Gerontol Soc Work. 2010;53(4):366-81.
58. Grov C, Golub SA, Parsons JT, Brennan M, Karpiak SE. Loneliness and HIV-related stigma explain depression among older HIV-positive adults. AIDS Care. 2010;22(5):630-9.
59. Poindexter C, Shippy RA. Networks of older New Yorkers with HIV: fragility, resilience, and transformation. AIDS Patient Care STDs. 2008;22(9):723-33.
60. Golub SA, Tomassilli JC, Pantalone DW, Brennan M, Karpiak SE, Parsons JT. Prevalence and correlates of sexual behavior and risk management among HIV-positive adults over 50. Sex Transm Dis. 2010;37(10):615.
61. Sacktor N, Skolasky R, Selnes OA, Watters M, Poff P, Shiramizu B, et al. Neuropsychological test profile differences between young and old human immunodeficiency virus-positive individuals. J Neurovirol. 2007;13(3):203-9.
62. Valcour V, Watters M, Williams A, Sacktor N, McMurtray A, Shikuma C. Aging exacerbates extrapyramidal motor signs in the era of highly active antiretroviral therapy. J Neurovirol. 2008;14(5):362-7.
63. Valcour V, Yee P, Williams AE, Shiramizu B, Watters M, Selnes O, et al. Lowest ever CD4 lymphocyte count (CD4 nadir) as a predictor of current cognitive and neurological status in human immunodeficiency virus type 1 infection - the Hawaii aging with HIV cohort. J Neurovirol. 2006;12(5):387-91.
64. Watters MR, Poff PW, Shiramizu BT, Holck PS, Fast KMS, Shikuma CM, et al. Symptomatic distal sensory polyneuropathy in HIV after age 50. Neurology. 2004;62(8):1378-83.
65. McMurtray A, Nakamoto B, Shikuma C, Valcour V. Small-vessel vascular disease in human immunodeficiency virus infection: the Hawaii aging with HIV cohort study. Cerebrovasc Dis. 2007;24(2-3):236-41.
66. Valcour V, Paul R, Neuhaus J, Shikuma C. The effects of age and HIV on neuropsychological performance. J Int Neuropsychol Soc. 2011;17(1):190-5.
67. Valcour V, Shikuma C, Shiramizu B, Williams A, Watters M, Grove JS, et al. Diabetes, insulin resistance, and dementia among HIV-1-infected patients. JAIDS. 2005;38(1):31-6.
68. Braithwaite RS, Roberts MS, Chang CCH, Goetz MB, Gibert CL, Rodriguez-Barradas MC, et al. Influence of alternative thresholds for initiating HIV treatment on quality-adjusted life expectancy: a decision model. Ann Intern Med. 2008;148(3):178-85.
69. Oursler KK, Goulet JL, Leaf DA, Akingicil A, Katzel LI, Justice A, et al. Association of comorbidity with physical disability in older HIV-infected adults. AIDS Patient Care STDs. 2006;20(11):782-91.
70. Green TC, Kershaw T, Lin H, Heimer R, Goulet JL, Kraemer KL, et al. Patterns of drug use and abuse among aging adults with and without HIV: a latent class analysis of a US Veteran cohort. Drug Alcohol Depend. 2010;110(3):208-20.
71. Justice AC, Zingmond DS, Gordon KS, Fultz SL, Goulet JL, King Jr, et al. Drug toxicity, HIV progression, or comorbidity of aging: does tipranavir use increase the risk of intracranial hemorrhage? Clin Infect Dis. 2008;47(9):1226-30.
72. Zingmond DS, Kilbourne AM, Justice AC, Wenger NS, Rodriguez-Barradas M, Rabeneck L, et al. Differences in symptom expression in older HIV-positive patients: the veterans aging cohort 3 site study and HIV cost and service utilization study experience. J Acquir Immune Defic Syndr. 2003;33(Suppl. 2):S84-92.
73. Braithwaite RS, Goulet J, Kudel I, Tsevat J, Justice AC. Quantifying the decrement in utility from perceived side effects of combination antiretroviral therapies in patients with HIV. Value Health. 2008;11(5):975-9.
74. Goulet JL, Fultz SL, Rimland D, Butt A, Gibert C, Rodriguez-Barradas M, et al. Aging and infectious diseases: do patterns of comorbidity vary by HIV status, age, and HIV severity? Clin Infect Dis. 2007;45(12):1593-601.
75. Butt AA, McGinnis K, Rodriguez-Barradas MC, Crystal S, Simberkoff M, Goetz MB, et al. HIV infection and the risk of diabetes mellitus. AIDS. 2009;23(10):1227-34.
76. Oursler KK, Goulet JL, Crystal S, Justice AC, Crothers K, Butt AA, et al. Association of age and comorbidity with physical function in HIV-infected and uninfected patients: results from the Veterans Aging Cohort Study. AIDS Patient Care STDs. 2011;25(1):13-20.
77. Nokes KM, Coleman CL, Hamilton MJ, Corless IB, Sefcik E, Kirksey KM, et al. Age-related effects on symptom status and health-related quality of life in persons with HIV/AIDS. Appl Nurs Res. 2011;24(1):10-6.
78. Worm SW, De Wit S, Weber R, Sabin CA, Reiss P, El-Sadr W, et al. Diabetes mellitus, preexisting coronary heart disease, and the risk of subsequent coronary heart disease events in patients infected with human immunodeficiency virus: the data collection on adverse events of anti-HIV drugs (D:A:D Study). Circulation. 2009;119(6):805-11.
79. Sabin C. Response to combination antiretroviral therapy: variation by age. AIDS. 2008;22(12):1463-73.
80. Carr A, Grund B, Neuhaus J, El-Sadr WM, Grandits G, Gibert C, et al. Asymptomatic myocardial ischaemia in HIV-infected adults. AIDS. 2008;22(2):237-47.
81. Popay J, Rogers A, Williams G. Rationale and standards for the systematic review of qualitative literature in health services research. Qual Health Res. 1998;8(3):341-51.
82. Grypdonck MHF. Qualitative health research in the era of evidence-based practice. Qual Health Res. 2006;16(10):1371-85.
83. Malterud K. The art and science of clinical knowledge: evidence beyond measures and numbers. The Lancet. 2001;358(9279):397-400.
84. Barbour RS. The case for combining qualitative and quantitative approaches in health services research. J Health Serv Res Policy. 1999;4(1):39-43.
85. Murray J, Adam BD. Aging, sexuality, and HIV issues among older gay men. Can J Hum Sex. 2001;10(3-4):75-90.
86. Lichtenstein B. Stigma as a barrier to treatment of sexually transmitted infection in the American deep south: issues of race, gender and poverty. Soc Sci Med. 2003;57(12):2435-45.
87. Gott M, Hinchliff S. How important is sex in later life? The views of older people. Soc Sci Med. 2003;56(8):1617-28.
88. Heckman T, Sikkema K, Hansen N, Kochman A, Heh V. A randomized clinical trial evaluating a coping improvement group intervention for HIV-infected older adults. J Behav Med. 2009;34(Suppl 1):102-11.
89. Heckman TG, Barcikowski R, Ogles B, Suhr J, Carlson B, Holroyd K, et al. A telephone-delivered coping improvement group intervention for middle-aged and older adults living with HIV/AIDS. Ann Behav Med. 2006;32(1):27-38.
90. Heckman TG, Kochman A, Sikkema KJ, Kalichman SC, Masten J, Bergholte J, et al. Pilot coping improvement intervention for late middle-aged and older adults living with HIV/AIDS in the USA. AIDS Care. 2001;13(1):129-39.
91. Neundorfer MM, Camp CJ, Lee MM, Skrajner MJ, Malone ML, Carr JR. Compensating for cognitive deficits in persons aged 50 and over with HIV/AIDS: a pilot study of a cognitive intervention. J HIV/AIDS Soc Serv. 2004;3(1):79-97.
92. Vance DE, Burrage J, Couch A Jr, Raper J. Promoting successful aging with HIV through hardiness: implications for nursing practice and research. J Gerontol Nurs. 2008;34(6):22-9.
93. Jimenez AD. Triple jeopardy: targeting older men of color who have sex with men. J Acquir Immune Defic Syndr. 2003;33(Suppl 2):S222-5.
94. Jacobs RJ, Thomlison B. Self-silencing and age as risk factors for sexually acquired HIV in midlife and older women. J Aging Health. 2009;21(1):102-28.
95. Appay V, Sauce D. Immune activation and inflammation in HIV-1 infection: causes and consequences. J Pathol. 2008;214(2):231-41.
96. Gandhi RT, Sax PE, Grinspoon SK. Metabolic and cardiovascular complications in HIV-infected patients: new challenges for a new age. J Infect Dis. 2012;205(suppl 3):S353-4.
97. Deeks SG, Verdin E, McCune JM. Immunosenescence and HIV. Curr Opin Immunol. 2012;24(4):501-6.
98. Pineda JA, Alcamí J, Blanco JR, Blanco J, Boix V, Casado JL, et al. Hot immunological topics in HIV infection. J AIDS Clin Res. 2011;2(118):2.
99. Ances BM, Ortega M, Vaida F, Heaps J, Paul R. Independent effects of HIV, aging, and HAART on brain volumetric measures. JAIDS. 2012;59(5):469-77.
100. Guaraldi G, Orlando G, Zona S, Menozzi M, Carli F, Garlassi E, et al. Premature age-related comorbidities among HIV-infected persons compared with the general population. Clin Infect Dis. 2011;53(11):1120-6.
101. Deeks SG. HIV infection, inflammation, immunosenescence, and aging. Annu Rev Med. 2011;62:141-55.
102. World Health Organization. Preamble to the Constitution of the World Health Organization as adopted by the International Health Conference, New York, 19-22 June, 1946; signed on 22 July 1946 by the representatives of 61 States (Official Records of the World Health Organization, no. 2, p. 100) and entered into force on 7 April 1948.