Skin microbiome imbalance in patients with STAT1/STAT3 defects impairs innate host defense responses

Journal of Innate Immunity

Volumn 6, Issue 3, 2014, Pages 253-262

  Smeekens, Sanne P ^a   Huttenhower, Curtis ^b,d   Riza, Anca ^a   Van De Veerdonk, Frank L ^a   Zeeuwen, Patrick L J M ^a   Schalkwijk, Joost ^a   Van Der Meer, Jos W M ^a   Xavier, Ramnik J ^b,c   Netea, Mihai G ^a   Gevers, Dirk ^b  

^a RADBOUD UNIVERSITY MEDICAL CENTER   (Netherlands)

^b HARVARD UNIVERSITY   (United States)

^c MASSACHUSETTS GENERAL HOSPITAL   (United States)

^d HARVARD SCHOOL OF PUBLIC HEALTH   (United States)

Author keywords

Candida; Chronic mucocutaneous candidiasis; Hyper IgE syndrome; Immunodeficiency; Microbiome

Indexed keywords

INTERLEUKIN 17; INTERLEUKIN 1BETA; INTERLEUKIN 22; RNA 16S; STAT1 PROTEIN; STAT3 PROTEIN; TUMOR NECROSIS FACTOR ALPHA; CYTOKINE; GAMMA INTERFERON;

ACINETOBACTER INFECTION; ADULT; ARTICLE; CANDIDA ALBICANS; CLINICAL ARTICLE; CONTROLLED STUDY; CORYNEBACTERIUM; CORYNEBACTERIUM INFECTION; CYTOKINE RESPONSE; FEMALE; GRAM NEGATIVE BACTERIUM; HOST RESISTANCE; HUMAN; HUMAN CELL; HYPER IGE SYNDROME; IMMUNE RESPONSE; IN VITRO STUDY; INNATE IMMUNITY; LEUKOCYTE; MALE; MICROBIOME; MUCOCUTANEOUS CANDIDIASIS; PRIORITY JOURNAL; PROTEIN DEFECT; RNA SEQUENCE; STAPHYLOCOCCUS; STAPHYLOCOCCUS INFECTION; ACINETOBACTER; BACTERIAL INFECTION; CELL CULTURE; DNA SEQUENCE; GENETICS; IMMUNOLOGY; IMMUNOSUPPRESSIVE TREATMENT; LYMPHOCYTE ACTIVATION; METABOLISM; MICROBIOLOGY; MICROFLORA; MIDDLE AGED; MONONUCLEAR CELL; MOUTH; MUTATION; SKIN; STAPHYLOCOCCUS AUREUS; CELL ISOLATION; DNA ISOLATION; FUSOBACTERIUM; GENE EXPRESSION PROFILING; GENE SEQUENCE; INFECTION RISK; INTERFERON PRODUCTION; MICROBIAL COMMUNITY; MOUTH FLORA; NONHUMAN; PERIPHERAL BLOOD MONONUCLEAR CELL; SKIN FLORA; STREPTOCOCCUS;

ACINETOBACTER; ADULT; BACTERIAL INFECTIONS; CANDIDA ALBICANS; CANDIDIASIS, CHRONIC MUCOCUTANEOUS; CELLS, CULTURED; CORYNEBACTERIUM; CYTOKINES; FEMALE; HUMANS; IMMUNITY, INNATE; IMMUNOSUPPRESSION; JOB SYNDROME; LEUKOCYTES, MONONUCLEAR; LYMPHOCYTE ACTIVATION; MALE; MICROBIOTA; MIDDLE AGED; MOUTH; MUTATION; RNA, RIBOSOMAL, 16S; SEQUENCE ANALYSIS, DNA; SKIN; STAPHYLOCOCCUS AUREUS; STAT1 TRANSCRIPTION FACTOR; STAT3 TRANSCRIPTION FACTOR;

EID: 84897458643     PISSN: 1662811X     EISSN: 16628128     Source Type: Journal    
DOI: 10.1159/000351912     Document Type: Article

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